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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

STK33 Gene

protein-coding   GIFtS: 54
GCID: GC11M008369

Serine/Threonine Kinase 33

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Serine/Threonine Kinase 331 2
Serine/Threonine-Protein Kinase 332
EC 2.7.11.13
EC 2.7.118

External Ids:    HGNC: 145681   Entrez Gene: 659752   Ensembl: ENSG000001304137   OMIM: 6076705   UniProtKB: Q9BYT33   

Export aliases for STK33 gene to outside databases

Previous GC identifers: GC11M009197 GC11M008873 GC11M008372 GC11M008377 GC11M008081


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for STK33 Gene: 
STK33 (serine/threonine kinase 33) is a protein-coding gene. Diseases associated with STK33 include thyroiditis, and prostatitis, and among its related super-pathways are Cellular Effects of Sildenafil. GO annotations related to this gene include protein serine/threonine kinase activity and ATP binding. An important paralog of this gene is DCLK3.

UniProtKB/Swiss-Prot: STK33_HUMAN, Q9BYT3
Function: Serine/threonine protein kinase which phosphorylates VIME. May play a specific role in the dynamic
behavior of the intermediate filament cytoskeleton by phosphorylation of VIME (By similarity). Not essential for
the survival of KRAS-dependent AML cell lines




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NT_009237.18  NC_018922.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the STK33 gene promoter:
         GR   ATF-2   GR-beta   FAC1   POU2F1   FOXO4   POU2F1a   c-Myb   c-Jun   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSTK33 promoter sequence
   Search SABiosciences Chromatin IP Primers for STK33

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat STK33


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.3   Ensembl cytogenetic band:  11p15.4   HGNC cytogenetic band: 11p15.3

STK33 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
STK33 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M008369:  view genomic region     (about GC identifiers)

Start:
8,413,418 bp from pter      End:
8,615,836 bp from pter
Size:
202,419 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: STK33_HUMAN, Q9BYT3 (See protein sequence)
Recommended Name: Serine/threonine-protein kinase 33  
Size: 514 amino acids; 57831 Da
Subunit: Interacts with VIME (By similarity)
Subcellular location: Cytoplasm, perinuclear region (By similarity)
Secondary accessions: Q658S6 Q8NEF5
Alternative splicing: 2 isoforms:  Q9BYT3-1   Q9BYT3-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for STK33: NX_Q9BYT3

Explore proteomics data for STK33 at MOPED 

Post-translational modifications:

  • UniProtKB: Autophosphorylated (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BYT3

  • 2 DME Specific Peptides for STK33 (Q9BYT3)
     RDLKLEN  IVHRDLK 

    STK33 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    STK33 Protein Expression
    REFSEQ proteins: NP_112168.1  
    ENSEMBL proteins: 
     ENSP00000416750   ENSP00000320754   ENSP00000379905   ENSP00000351743   ENSP00000415688  
     ENSP00000436418   ENSP00000436905   ENSP00000391362   ENSP00000411510   ENSP00000403599  
     ENSP00000397569   ENSP00000397874   ENSP00000432822   ENSP00000379906  

    Human Recombinant Protein Products for STK33: 
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    Novus Biologicals STK33 Protein
    Novus Biologicals STK33 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for STK33 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005794Golgi apparatus IDA--
    GO:0048471perinuclear region of cytoplasm IEA--

    STK33 for ontologies           About GeneDecksing



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    Assay Products for STK33: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    IUPHAR Guide to PHARMACOLOGY protein family classification: serine/threonine kinase 33 
    CAMK-unique family

    5/6 InterPro protein domains (see all 6):
     IPR017441 Protein_kinase_ATP_BS
     IPR002290 Ser/Thr_dual-sp_kinase_dom
     IPR011009 Kinase-like_dom
     IPR008271 Ser/Thr_kinase_AS
     IPR000719 Prot_kinase_cat_dom

    Graphical View of Domain Structure for InterPro Entry Q9BYT3

    ProtoNet protein and cluster: Q9BYT3

    UniProtKB/Swiss-Prot: STK33_HUMAN, Q9BYT3
    Similarity: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily
    Similarity: Contains 1 protein kinase domain


    STK33 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: STK33_HUMAN, Q9BYT3
    Function: Serine/threonine protein kinase which phosphorylates VIME. May play a specific role in the dynamic
    behavior of the intermediate filament cytoskeleton by phosphorylation of VIME (By similarity). Not essential for
    the survival of KRAS-dependent AML cell lines
    Catalytic activity: ATP + a protein = ADP + a phosphoprotein

         Enzyme Numbers (IUBMB): EC 2.7.112 EC 2.7.11.11

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004672protein kinase activity ----
    GO:0004674protein serine/threonine kinase activity ISS--
    GO:0004713protein tyrosine kinase activity ----
    GO:0005515protein binding ----
    GO:0005524ATP binding IEA--
         
    STK33 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for STK33:
     Decreased Salmonella enterica   Decreased substrate adherent c  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for STK33 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for STK33

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for STK33 
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    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat STK33
    8/31 QIAGEN miScript miRNA Assays for microRNAs that regulate STK33 (see all 31):
    hsa-miR-15a hsa-miR-106a hsa-miR-301a hsa-miR-944 hsa-miR-885-5p hsa-miR-519a hsa-miR-424 hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidSTK33 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STK33


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for STK33 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Sweet Taste Signaling
    Sperm Motility0.37

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for STK33
        Sperm Motility



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for STK33

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for STK33 (Q9BYT33 ENSP000003207544) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EEF1DP296923I2D: score=1 
    HDAC3ENSP000003029674STRING: ENSP00000302967
    GLYCTKENSP000003891754STRING: ENSP00000389175
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006468protein phosphorylation ----
    GO:0046777protein autophosphorylation ISS--

    STK33 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for STK33

    Search CenterWatch for drugs/clinical trials and news about STK33

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for STK33 gene: 
    NM_030906.2  

    Unigene Cluster for STK33:

    Serine/threonine kinase 33
    Hs.501833  [show with all ESTs]
    Unigene Representative Sequence: AK122808
    18 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000473980 ENST00000486305 ENST00000447869(uc001mgi.1) ENST00000315204(uc001mgj.1)
    ENST00000396672(uc001mgk.1 uc010rbn.1) ENST00000358872(uc001mgl.3)
    ENST00000444064 ENST00000534493 ENST00000526517(uc009yfp.3) ENST00000524760
    ENST00000418597 ENST00000422559 ENST00000457885 ENST00000532336 ENST00000431279
    ENST00000454443 ENST00000526360 ENST00000396673
    miRNA
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    8/31 QIAGEN miScript miRNA Assays for microRNAs that regulate STK33 (see all 31):
    hsa-miR-15a hsa-miR-106a hsa-miR-301a hsa-miR-944 hsa-miR-885-5p hsa-miR-519a hsa-miR-424 hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidSTK33 3' UTR sequence
    Inhib. RNA
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for STK33
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat STK33
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat STK33
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat STK33

    Additional mRNA sequence: 

    AJ303380.2 AK092720.1 AK093251.1 AK122808.1 AK293193.1 AK310754.1 AL833011.1 BC031231.1 

    11 DOTS entries:

    DT.100774894  DT.106654  DT.91658602  DT.100774896  DT.95100842  DT.99927657  DT.120683471  DT.86847843 
    DT.91743568  DT.100774347  DT.92066347 

    24/89 AceView cDNA sequences (see all 89):

    CB306028 AL041049 AI818743 AA297313 AI818734 AA886440 AW118625 NM_030906 
    AI267885 BI830742 BE218817 AJ303380 N67346 BE327549 BE326215 CA312615 
    BM975518 AI818733 BE670014 BE504022 BE219074 BI464341 AW268879 AI198872 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    STK33 expression in normal human tissues (normalized intensities)      STK33 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGTTCGTGAG
    STK33 Expression
    About this image


    STK33 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Epithelium (Respiratory System)    fully expand to see all 2 entries
             bronchial epithelial cells   
     
     Pancreas (Endocrine System)
             Posterior foregut-like cells ( A scalable, suspension protocol for derivation of...
     
     Testis (Reproductive System)

    See STK33 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for STK33

    SOURCE GeneReport for Unigene cluster: Hs.501833

    UniProtKB/Swiss-Prot: STK33_HUMAN, Q9BYT3
    Tissue specificity: Highly expressed in testis, fetal lung and heart, followed by pituitary gland, kidney,
    interventricular septum, pancreas, heart, trachea, thyroid gland and uterus. Weak hybridization signals were
    observed in the following tissues: amygdala, aorta, esophagus, colon ascending, colon transverse, skeletal
    muscle, spleen, peripheral blood leukocyte, lymph node, bone marrow, placenta, prostate, liver, salivary gland,
    mammary gland, some tumor cell lines, fetal brain, fetal liver, fetal spleen and fetal thymus. No signal at all
    was detectable in RNA from tissues of the nervous system

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STK33

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for STK33 gene from 4/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Stk331 , 5 serine/threonine kinase 331, 5 78.84(n)1
    71.63(a)1
      7 (57.21 cM)5
    1172291  NM_054103.11  NP_473444.11 
     1092792235 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia 1420182302   -- 72.53(n)    142018230 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.187682 Transcribed sequence with weak similarity to protein more 72.57(n)    BQ617398.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes NNK16
    Protein kinase; implicated in proteasome function;...
    8(a)
    1 → many
    XI(127475-130261)


    ENSEMBL Gene Tree for STK33 (if available)
    TreeFam Gene Tree for STK33 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for STK33 gene
    DCLK32  DCX2  PRKD32  PRKD22  DCLK22  DCLK12  PRKD12  
    18/64 SIMAP similar genes for STK33 using alignment to 12 protein entries:     STK33_HUMAN (see all proteins) (see all similar genes):
    BRSK2    STK36    MARK4    HUNK    CAMK1D    NUAK1
    RPS6KA1    MAPKAPK3    CAMK1    PLK4    RPS6KA4    PRKAA1
    MARK2    CAMK1G    CAMKV    MST094    RPS6KA2    RPS6KA3

    STK33 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for STK33
    PGOHUM00000236668


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/4126 SNPs in STK33 are shown (see all 4126)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0411734
    A lung large cell carcinoma sample4--see VAR_0411732 L V mis40--------
    rs1386670211,2
    --8413135(+) CTTTAC/TGAAGG 1 -- ds50010--------
    rs1428674691,2
    C--8413150(+) AGCAAC/TTGCAA 1 -- ds50010--------
    rs1469953721,2
    --8413205(+) TTCAAC/TCAGTT 1 -- ds50010--------
    rs1381042891,2
    C--8413332(+) TACCAC/TTGCAG 1 -- ds50010--------
    rs734020671,2
    C,F--8413360(+) AATTTG/CCATAA 1 -- ds50014Minor allele frequency- C:0.14WA CSA NA 242
    rs1877117811,2
    --8413396(+) ACCTCC/TTGTTA 1 -- ds50010--------
    rs734020681,2
    C,F--8413407(+) ACATAA/CAAATT 1 -- ds50014Minor allele frequency- C:0.15WA CSA NA 242
    rs1435320581,2
    C--8413528(+) AAGCTA/GTCTTA 1 -- ut310--------
    rs1926260721,2
    --8413561(+) TCTCAC/TGAACA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for STK33 (8413418 - 8615836 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for STK33:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2667808CNV Deletion23128226
    esv2657808CNV Deletion23128226
    esv2751035CNV Loss17911159
    nsv519052CNV Loss19592680
    nsv471747CNV Loss16327809
    nsv896983CNV Loss21882294
    esv32551CNV Loss17666407
    nsv7215OTHER Inversion18451855
    nsv499766OTHER Inversion21111241


    Human Gene Mutation Database (HGMD): STK33
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing STK33
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607670    OMIM disorders: --

    3 diseases for STK33:    About MalaCards
    thyroiditis    prostatitis    neuronitis


    STK33 for disorders           About GeneDecksing

    Genetic Association Database (GAD): STK33
    Human Genome Epidemiology (HuGE) Navigator: STK33 (2 documents)

    Export disorders for STK33 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for STK33 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with STK33)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel serine/threonine kinase gene, STK33, on human chromosome 11p15.3. (PubMed id 11738831)1, 2, 3 Mujica A.O.... Schmidt E.R. (2001)
    2. STk33 kinase activity is non-essential in KRAS-dependent cancer cells. (PubMed id 21742770)1, 2 Babij C.... Dussault I. (2011)
    3. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. (PubMed id 20935630)1, 4 Speliotes E.K....Loos R.J. (2010)
    4. Evaluating the discriminative power of multi-trait ge netic risk scores for type 2 diabetes in a northern Swedish population. (PubMed id 20571754)1, 4 Fontaine-Bisson B....Franks P.W. (2010)
    5. Analyses of shared genetic factors between asthma and obesity in children. (PubMed id 20816195)1, 4 MelAcn E....Lasky-Su J. (2010)
    6. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. (PubMed id 19079261)1, 4 Willer C.J....Hirschhorn J.N. (2009)
    7. Differential expression pattern of the novel serine/threonine kinase, STK33, in mice and men. (PubMed id 16176263)1, 2 Mujica A.O....Schmidt E.R. (2005)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    10. Targeting of KRAS mutant tumors by HSP90 inhibitors in volves degradation of STK33. (PubMed id 22451720)1 Azoitei N....Scholl C. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 65975 HGNC: 14568 AceView: STK33 Ensembl:ENSG00000130413 euGenes: HUgn65975
    ECgene: STK33 H-InvDB: STK33

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for STK33 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for STK33 gene:
    Search GeneIP for patents involving STK33

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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