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Aliases for STK32C Gene

Aliases for STK32C Gene

  • Serine/Threonine Kinase 32C 2 3
  • Yet Another Novel Kinase 3 3 4
  • EC 2.7.11.1 4 63
  • YANK3 3 4
  • PKE 3 4
  • Serine/Threonine-Protein Kinase 32C 3
  • Protein Kinase (PKE) 3
  • PKE Protein Kinase 3
  • EC 2.7.11 63

External Ids for STK32C Gene

Previous GeneCards Identifiers for STK32C Gene

  • GC10M133456
  • GC10M133870
  • GC10M134020
  • GC10M127572

Summaries for STK32C Gene

Entrez Gene Summary for STK32C Gene

  • The protein encoded by this gene is a member of the serine/threonine protein kinase family. The specific function of this kinase is not known. [provided by RefSeq, Jul 2008]

GeneCards Summary for STK32C Gene

STK32C (Serine/Threonine Kinase 32C) is a Protein Coding gene. Among its related pathways are Sweet Taste Signaling. GO annotations related to this gene include protein serine/threonine kinase activity. An important paralog of this gene is STK32B.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for STK32C Gene

Genomics for STK32C Gene

Regulatory Elements for STK32C Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for STK32C Gene

Start:
132,207,482 bp from pter
End:
132,331,847 bp from pter
Size:
124,366 bases
Orientation:
Minus strand

Genomic View for STK32C Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for STK32C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for STK32C Gene

Proteins for STK32C Gene

  • Protein details for STK32C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86UX6-ST32C_HUMAN
    Recommended name:
    Serine/threonine-protein kinase 32C
    Protein Accession:
    Q86UX6
    Secondary Accessions:
    • Q5T0Q5
    • Q86UE1

    Protein attributes for STK32C Gene

    Size:
    486 amino acids
    Molecular mass:
    54994 Da
    Cofactor:
    Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for STK32C Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for STK32C Gene

Proteomics data for STK32C Gene at MOPED

Selected DME Specific Peptides for STK32C Gene

Post-translational modifications for STK32C Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for STK32C Gene

Domains for STK32C Gene

Suggested Antigen Peptide Sequences for STK32C Gene

Graphical View of Domain Structure for InterPro Entry

Q86UX6

UniProtKB/Swiss-Prot:

ST32C_HUMAN :
  • Q86UX6
Domain:
  • Contains 1 protein kinase domain.
Family:
  • Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
genes like me logo Genes that share domains with STK32C: view

Function for STK32C Gene

Molecular function for STK32C Gene

UniProtKB/Swiss-Prot CatalyticActivity: ATP + a protein = ADP + a phosphoprotein.

Enzyme Numbers (IUBMB) for STK32C Gene

Gene Ontology (GO) - Molecular Function for STK32C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004672 protein kinase activity --
GO:0004674 protein serine/threonine kinase activity IEA --
GO:0004713 protein tyrosine kinase activity --
GO:0005524 ATP binding IEA --
GO:0016772 transferase activity, transferring phosphorus-containing groups --
genes like me logo Genes that share ontologies with STK32C: view

Phenotypes for STK32C Gene

genes like me logo Genes that share phenotypes with STK32C: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for STK32C

In Situ Assay Products

Flow Cytometry Products

No data available for Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for STK32C Gene

Localization for STK32C Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for STK32C Gene COMPARTMENTS Subcellular localization image for STK32C gene
Compartment Confidence
cytosol 3
nucleus 2
mitochondrion 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for STK32C Gene

Pathways for STK32C Gene

SuperPathways for STK32C Gene

Superpath Contained pathways
1 Sweet Taste Signaling
genes like me logo Genes that share pathways with STK32C: view

Pathways by source for STK32C Gene

1 Qiagen pathway for STK32C Gene

Gene Ontology (GO) - Biological Process for STK32C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006468 protein phosphorylation IEA --
genes like me logo Genes that share ontologies with STK32C: view

Compounds for STK32C Gene

(3) HMDB Compounds for STK32C Gene

Compound Synonyms Cas Number PubMed IDs
Adenosine triphosphate
  • 5'-(tetrahydrogen triphosphate) Adenosine
56-65-5
ADP
  • adenosindiphosphorsaeure
58-64-0
Magnesium
  • Magnesium
7439-95-4
genes like me logo Genes that share compounds with STK32C: view

Transcripts for STK32C Gene

Unigene Clusters for STK32C Gene

Serine/threonine kinase 32C:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for STK32C

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for STK32C

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for STK32C Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16
SP1: - -
SP2: - - - - - - - - -
SP3: - - - - - - -
SP4: -
SP5:
SP6: - -
SP7: - - - -
SP8: - - - -

Relevant External Links for STK32C Gene

GeneLoc Exon Structure for
STK32C
ECgene alternative splicing isoforms for
STK32C

Expression for STK32C Gene

mRNA expression in normal human tissues for STK32C Gene

mRNA differential expression in normal tissues according to GTEx for STK32C Gene

This gene is overexpressed in Brain - Cortex (4.6).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for STK32C Gene

SOURCE GeneReport for Unigene cluster for STK32C Gene Hs.469002

genes like me logo Genes that share expressions with STK32C: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for STK32C Gene

Orthologs for STK32C Gene

This gene was present in the common ancestor of animals.

Orthologs for STK32C Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia STK32C 35
  • 99.31 (n)
  • 99.38 (a)
STK32C 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia STK32C 35
  • 90.44 (n)
  • 92.65 (a)
STK32C 36
  • 92 (a)
OneToOne
dog
(Canis familiaris)
Mammalia STK32C 35
  • 89.06 (n)
  • 91.73 (a)
STK32C 36
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Stk32c 35
  • 87.52 (n)
  • 91.36 (a)
Stk32c 16
Stk32c 36
  • 91 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia STK32C 36
  • 87 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia STK32C 36
  • 86 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Stk32c 35
  • 87.72 (n)
  • 91.77 (a)
chicken
(Gallus gallus)
Aves STK32C 35
  • 80.85 (n)
  • 82.69 (a)
STK32C 36
  • 80 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia STK32C 36
  • 84 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia stk32c 35
  • 71.45 (n)
  • 79.06 (a)
zebrafish
(Danio rerio)
Actinopterygii CABZ01072625.1 36
  • 88 (a)
OneToMany
CABZ01092745.1 36
  • 49 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG32944 36
  • 37 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea M03C11.1 36
  • 42 (a)
OneToMany
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.12751 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 38 (a)
OneToMany
Species with no ortholog for STK32C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for STK32C Gene

ENSEMBL:
Gene Tree for STK32C (if available)
TreeFam:
Gene Tree for STK32C (if available)

Paralogs for STK32C Gene

Paralogs for STK32C Gene

genes like me logo Genes that share paralogs with STK32C: view

Variants for STK32C Gene

Sequence variations from dbSNP and Humsavar for STK32C Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs15711 -- 132,207,688(+) CCTCC(A/G)GGCTG utr-variant-3-prime, nc-transcript-variant
rs870427 -- 132,226,387(-) AGAGC(C/T)GGTGT intron-variant
rs902628 -- 132,225,143(+) CCTGG(A/G)CACTG intron-variant
rs902629 -- 132,225,211(+) AGCCC(A/G)GGGGC intron-variant
rs902630 -- 132,255,265(-) CAGGA(C/G)CCCCG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for STK32C Gene

Variant ID Type Subtype PubMed ID
nsv896120 CNV Loss 21882294
nsv896122 CNV Loss 21882294
nsv832030 CNV Loss 17160897
dgv839n71 CNV Loss 21882294
dgv841n71 CNV Loss 21882294
nsv896140 CNV Loss 21882294
nsv896141 CNV Loss 21882294
dgv843n71 CNV Loss 21882294
dgv844n71 CNV Loss 21882294
dgv845n71 CNV Loss 21882294
esv272068 CNV Insertion 20981092
esv2661595 CNV Deletion 23128226
esv2743637 CNV Deletion 23290073
nsv896149 CNV Loss 21882294
nsv470975 CNV Gain 18288195
nsv896150 CNV Loss 21882294
esv2743638 CNV Deletion 23290073
esv2743639 CNV Deletion 23290073
esv2109501 CNV Deletion 18987734
esv2743640 CNV Deletion 23290073
esv2676420 CNV Deletion 23128226
esv2743642 CNV Deletion 23290073
esv2743643 CNV Deletion 23290073
esv2743644 CNV Deletion 23290073
nsv467490 CNV Loss 19166990
nsv896151 CNV Loss 21882294
esv2743645 CNV Deletion 23290073
esv2743646 CNV Deletion 23290073
nsv24619 CNV Insertion 16902084
esv1920267 CNV Deletion 18987734
dgv135e201 CNV Deletion 23290073
esv2676196 CNV Deletion 23128226
esv1302998 CNV Insertion 17803354
esv2743649 CNV Deletion 23290073
esv2490403 CNV Deletion 19546169
esv2743650 CNV Deletion 23290073
esv2743651 CNV Deletion 23290073
esv2743653 CNV Deletion 23290073
esv1144814 CNV Insertion 17803354

Relevant External Links for STK32C Gene

HapMap Linkage Disequilibrium report
STK32C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for STK32C Gene

Disorders for STK32C Gene

Relevant External Links for STK32C

Genetic Association Database (GAD)
STK32C
Human Genome Epidemiology (HuGE) Navigator
STK32C
genes like me logo Genes that share disorders with STK32C: view

No data available for UniProtKB/Swiss-Prot for STK32C Gene

Publications for STK32C Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Replication of recently described type 2 diabetes gene variants in a South Indian population. (PMID: 20580033) Chidambaram M. … Mohan V. (Metab. Clin. Exp. 2010) 3 48
  4. The protein kinase complement of the human genome. (PMID: 12471243) Manning G. … Sudarsanam S. (Science 2002) 3 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for STK32C Gene

  • antibodies-online proteins for STK32C
  • antibodies-online antibodies for STK32C
  • antibodies-online kits for STK32C

Sources for STK32C Gene

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