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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

STK19 Gene

protein-coding   GIFtS: 58
GCID: GC06P031938

Serine/Threonine Kinase 19

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Serine/Threonine Kinase 191 2     MHC Class III HLA-RP12
G112 3     Nuclear Serine/Threonine Protein Kinase2
RP12 3     Serine/Threonine-Protein Kinase 192
D6S602     EC 2.7.11.13
D6S60E2     Protein G113
HLA-RP12     Protein RP13

External Ids:    HGNC: 113981   Entrez Gene: 88592   Ensembl: ENSG000002043447   OMIM: 6049775   UniProtKB: P498423   
ORGUL members:         
NONCODE14:n407254      

Export aliases for STK19 gene to outside databases

Previous GC identifers: GC06P032001 GC06P031710 GC06P032043 GC06P032047 GC06P031725


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for STK19 Gene:
This gene encodes a serine/threonine kinase which localizes predominantly to the nucleus. Its specific function is
unknown; it is possible that phosphorylation of this protein is involved in transcriptional regulation. This gene
localizes to the major histocompatibility complex (MHC) class III region on chromosome 6 and expresses two
transcript variants. (provided by RefSeq, Jul 2008)

GeneCards Summary for STK19 Gene: 
STK19 (serine/threonine kinase 19) is a protein-coding gene, and is affiliated with the lncRNA class. Diseases associated with STK19 include orchitis, and 21-hydroxylase deficiency, and among its related super-pathways are Cellular Effects of Sildenafil. GO annotations related to this gene include protein serine/threonine kinase activity and ATP binding.

UniProtKB/Swiss-Prot: STK19_HUMAN, P49842
Function: Seems to be a protein kinase. In vitro it can phosphorylate casein-alpha on serine and threonine
residues and histones on serine residues

Gene Wiki entry for STK19 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.2  NT_007592.15  NT_113891.2  NT_167245.1  NT_167247.1  NT_167248.1  NT_167249.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the STK19 gene promoter:
         E2F-4   Max   E2F-5   Pax-5   AP-1   NF-kappaB   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): STK19 promoter sequence
   Search SABiosciences Chromatin IP Primers for STK19

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat STK19


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p21.33   HGNC cytogenetic band: 6p21.33

STK19 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
STK19 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P031938:  view genomic region     (about GC identifiers)

Start:
31,938,868 bp from pter      End:
31,950,598 bp from pter
Size:
11,731 bases      Orientation:
plus strand

5 alternative locations:
Chr6+,NT_167247 3,318,796-3,329,068      Chr6+,NT_167249 3,271,662-3,281,933      Chr6+,NT_167248 3,232,741-3,243,013     
Chr6+,NT_167245 3,224,535-3,234,804      Chr6+,NT_113891.2 3,448,708-3,458,979     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: STK19_HUMAN, P49842 (See protein sequence)
Recommended Name: Serine/threonine-protein kinase 19  
Size: 368 amino acids; 40916 Da
Cofactor: Divalent cations. Has a preference for manganese
Subunit: The N-terminus interacts with BAG1
Subcellular location: Nucleus
Secondary accessions: A6NF95 A6NFW8 B0QZR5 Q13159 Q31617 Q5JP77 Q5ST72 Q5ST75
Alternative splicing: 4 isoforms:  P49842-1   P49842-2   P49842-3   P49842-4   

Explore the universe of human proteins at neXtProt for STK19: NX_P49842

Explore proteomics data for STK19 at MOPED 

STK19 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

STK19 Protein Expression

REFSEQ proteins (2 alternative transcripts): 
NP_004188.1  NP_115830.1  

ENSEMBL proteins: 
 ENSP00000418350   ENSP00000364480   ENSP00000364482   ENSP00000418866   ENSP00000454870  

Human Recombinant Protein Products for STK19: 
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Novus Biologicals STK19 Lysates
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Browse Sino Biological Cell Lysates 
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for STK19 

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IEA--

STK19 for ontologies           About GeneDecksing



STK19 Antibody Products: 
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Cloud-Clone Corp. ELISAs for STK19 
Cloud-Clone Corp. CLIAs for STK19


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
IUPHAR Guide to PHARMACOLOGY protein family classification: serine/threonine kinase 19 
G11 family

1 InterPro protein domain:
 IPR018865 Ser/Thr_kinase_19

Graphical View of Domain Structure for InterPro Entry P49842

ProtoNet protein and cluster: P49842

UniProtKB/Swiss-Prot: STK19_HUMAN, P49842
Similarity: Belongs to the STK19 family


STK19 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: STK19_HUMAN, P49842
Function: Seems to be a protein kinase. In vitro it can phosphorylate casein-alpha on serine and threonine
residues and histones on serine residues
Catalytic activity: ATP + a protein = ADP + a phosphoprotein

     Genatlas biochemistry entry for STK19:
serine/threonine 19,widely expressed

     Enzyme Number (IUBMB): EC 2.7.11.11

     Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0004674protein serine/threonine kinase activity IEA--
GO:0005524ATP binding IEA--
     
STK19 for ontologies           About GeneDecksing


Phenotypes:
     5 GenomeRNAi human phenotypes for STK19:
 Decreased 12E8 and total tau p  Decreased focal adhesion (FA)   Decreased nuclei size in G2M  Decreased substrate adherent c 
 Decreased telomerase activity 

Animal Models:
   inGenious Targeting Laboratory - Custom generated mouse model solutions for STK19 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for STK19

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for STK19 
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for STK19 

miRNA
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QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat STK19
5 QIAGEN miScript miRNA Assays for microRNAs that regulate STK19:
hsa-miR-182 hsa-miR-3202 hsa-miR-1271 hsa-miR-4290 hsa-miR-96
SwitchGear 3'UTR luciferase reporter plasmidSTK19 3' UTR sequence
Inhib. RNA
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Gene Editing
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Clone
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OriGene ORF clones in mouse, rat for STK19
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector (see all 2): STK19 (NM_004197)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for STK19
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat STK19
Sirion Biotech Customized lentivirus for stable overexpression of STK19 
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Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STK19


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for STK19 About                                                                                                See pathways by source

SuperPathContained pathways About
1Sweet Taste Signaling
Sperm Motility0.37

1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for STK19
    Sperm Motility


Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for STK19

STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

5/7 Interacting proteins for STK19 (P498422, 3 ENSP000003644824) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
InteractantInteraction Details
GeneCardExternal ID(s)
POLR2GP624872, 3, ENSP000003017884MINT-62582 MINT-62756 MINT-62680 I2D: score=5 STRING: ENSP00000301788
SLC29A1Q998082, 3, ENSP000003607734MINT-62585 MINT-62759 MINT-62683 I2D: score=5 STRING: ENSP00000360773
PRAMEP783952, 3MINT-62760 MINT-62684 MINT-62586 I2D: score=5 
SF3B4Q154272, 3, ENSP000002716284MINT-62583 MINT-62681 MINT-62757 I2D: score=4 STRING: ENSP00000271628
SP3Q024472, 3, ENSP000003103014MINT-62758 MINT-62584 MINT-62682 I2D: score=5 STRING: ENSP00000310301
About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006468protein phosphorylation TAS9812991

STK19 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

STK19 for compounds           About GeneDecksing

Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for STK19

1 HMDB Compound for STK19    About this table
CompoundSynonyms CAS #PubMed Ids
Manganesemanganese 7439-96-5--

3 Novoseek inferred chemical compound relationships for STK19 gene    About this table
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
threonine 50.6 2 14730433 (1), 9812991 (1)
leucine 40.7 1 11487501 (1)
serine 37.7 2 14730433 (1), 9812991 (1)

Search CenterWatch for drugs/clinical trials and news about STK19

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for STK19 gene (2 alternative transcripts): 
NM_004197.1  NM_032454.1  

Unigene Cluster for STK19:

Serine/threonine kinase 19
Hs.654371  [show with all ESTs]
Unigene Representative Sequence: BC110347
17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000466132(uc003nyt.3 uc011dox.1) ENST00000460018 ENST00000479644(uc011dow.2)
ENST00000375331(uc003nyv.3 uc003nyw.3) ENST00000492583 ENST00000375333
ENST00000473983 ENST00000478486 ENST00000463823 ENST00000483801 ENST00000519179(uc010jtn.1)
ENST00000466336 ENST00000471028 ENST00000491861 ENST00000484540 ENST00000469907
ENST00000490822
miRNA
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5 QIAGEN miScript miRNA Assays for microRNAs that regulate STK19:
hsa-miR-182 hsa-miR-3202 hsa-miR-1271 hsa-miR-4290 hsa-miR-96
SwitchGear 3'UTR luciferase reporter plasmidSTK19 3' UTR sequence
Inhib. RNA
Products:
     
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QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat STK19
Clone
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GenScript: all cDNA clones in your preferred vector (see all 2): STK19 (NM_004197)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for STK19
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat STK19
Sirion Biotech Customized lentivirus for stable overexpression of STK19 
                     Customized lentivirus expression plasmids for stable overexpression of STK19 
Primer
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OriGene qSTAR qPCR primer pairs in human, mouse for STK19
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat STK19
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat STK19
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat STK19

Additional mRNA sequence: 

AK302111.1 AK303438.1 AK307198.1 BC016916.1 BC110347.1 BC121128.1 BC121129.1 BC143833.1 
BC143835.1 L26260.1 NR_026717.1 X77386.1 

19 DOTS entries:

DT.100816356  DT.447275  DT.121361862  DT.112296  DT.91752624  DT.100651903  DT.91886413  DT.121361941 
DT.95376283  DT.99971224  DT.70105173  DT.91752622  DT.95296222  DT.75104153  DT.91680425  DT.95344329 
DT.97808774  DT.121361728  DT.121361950 

24/86 AceView cDNA sequences (see all 86):

BQ438873 BU190873 BQ709330 CR605584 AI973206 CB140909 BM706985 BU684299 
BE645152 BU624370 BQ925245 W81583 CD742645 BI754476 AI245636 AL552424 
BC016916 CD673228 BG339903 CB528746 L26260 NM_032454 BX646605 BQ009080 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

STK19 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: TTAAAATTGC
STK19 Expression
About this image


See STK19 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for STK19

SOURCE GeneReport for Unigene cluster: Hs.654371

UniProtKB/Swiss-Prot: STK19_HUMAN, P49842
Tissue specificity: Monocytes, hepatocytes, epithelial cells, T- and B-lymphocytes

    SABiosciences Custom PCR Arrays for STK19
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QIAGEN QuantiFast Probe-based Assays in human, mouse, rat STK19
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STK19

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for STK19 gene from 6/14 species (see all 14)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Stk191 , 5 serine/threonine kinase 191, 5 82.41(n)1
85.83(a)1
  17 (18.38 cM)5
544021  NM_019442.31  NP_062315.11 
 348239935 
lizard
(Anolis carolinensis)
Reptilia STK196
serine/threonine kinase 19
53(a)
1 ↔ 1
2(194130739-194139791)
African clawed frog
(Xenopus laevis)
Amphibia Xl.225072 Xenopus laevis transcribed sequence with weak similarity more 74.82(n)    48033996 
zebrafish
(Danio rerio)
Actinopterygii LOC1001504971 serine/threonine-protein kinase 19-like 58.57(n)
53.91(a)
  100150497  XM_001923271.3  XP_001923306.1 
thale cress
(Arabidopsis thaliana)
eudicotyledons AT2G204951 hypothetical protein 45.48(n)
35.47(a)
  816570  NM_179670.3  NP_850001.3 
rice
(Oryza sativa)
Liliopsida Os07g04588001 hypothetical protein 44.12(n)
34.03(a)
  4343157  NM_001066106.1  NP_001059571.1 


ENSEMBL Gene Tree for STK19 (if available)
TreeFam Gene Tree for STK19 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/107 SNPs in STK19 are shown (see all 107)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 6 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
VAR_0423614
A metastatic melanoma sample4--see VAR_0423612 D N mis40--------
VAR_0513874
----see VAR_0513872 A D mis40--------
VAR_0423634
----see VAR_0423632 A V mis40--------
VAR_0423624
----see VAR_0423622 S G mis40--------
rs114044311,2
C--31942057(+) AAAAA-/AGTAAC 3 -- int1 trp31Minor allele frequency- A:0.00NA 2
rs3773701,2
C,F,A,H--31942514(-) tctgtT/Caccca 3 -- int17Minor allele frequency- C:0.25NA CSA WA 248
rs1807458781,2
--31942550(+) AAAACA/CACAAC 3 -- int10--------
rs557126381,2
C--31942732(+) AAGGAA/GTATTT 3 -- int10--------
rs742905271,2
C--31942872(+) AAACTA/GTAGAA 3 -- int10--------
rs1413466721,2
--31943008(+) GAGTGC/TCGCTC 3 -- int10--------

HapMap Linkage Disequilibrium report for STK19 (31938868 - 31950598 bp)

Structural Variations
     Database of Genomic Variants (DGV) 10/49 variations for STK19 (see all 49):    About this table     
Variant IDTypeSubtypePubMed ID
esv2731825CNV Deletion23290073
esv2666636CNV Deletion23128226
dgv20n31CNV Duplication19718026
nsv884665CNV Loss21882294
dgv6631n71CNV Loss21882294
nsv884626CNV Loss21882294
nsv285CNV Loss15895083
dgv6609n71CNV Loss21882294
nsv884514CNV Loss21882294
dgv6624n71CNV Loss21882294


Human Gene Mutation Database (HGMD): STK19
SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing STK19
DNA2.0 Custom Variant and Variant Library Synthesis for STK19

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 604977    OMIM disorders: --

8 diseases for STK19:    About MalaCards
orchitis    21-hydroxylase deficiency    diarrhea    meningioma
systemic lupus erythematosus    lupus erythematosus    schizophrenia    leukemia


STK19 for disorders           About GeneDecksing

Genetic Association Database (GAD): STK19
Human Genome Epidemiology (HuGE) Navigator: STK19 (11 documents)

Export disorders for STK19 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for STK19 gene, integrated from 9 sources (see all 26):
(articles sorted by number of sources associating them with STK19)
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  1. The G11 gene located in the major histocompatibility complex encodes a novel nuclear serine/threonine protein kinase. (PubMed id 9812991)1, 2, 3, 9 Gomez-Escobar N.... Campbell R.D. (1998)
  2. Characterisation of the novel gene G11 lying adjacent to the complement C4A gene in the human major histocompatibility complex. (PubMed id 8012361)1, 2, 3, 9 Sargent C.A.... Campbell R.D. (1994)
  3. Polymorphisms in innate immunity genes and risk of ch ildhood leukemia. (PubMed id 20438785)1, 4 Han S....Kang D. (2010)
  4. Risk of meningioma and common variation in genes rela ted to innate immunity. (PubMed id 20406964)1, 4 Rajaraman P....Inskip P.D. (2010)
  5. Host determinants of HIV-1 control in African America ns. (PubMed id 20205591)1, 4 Pelak K....Weintrob A.C. (2010)
  6. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
  7. High-density SNP screening of the major histocompatib ility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PubMed id 19851445)1, 4 Barcellos L.F....Criswell L.A. (2009)
  8. Characterization of Hap/BAG-1 variants as RP1 binding proteins with antiapoptotic activity. (PubMed id 15986447)1, 2 Wadle A.... Renner C. (2005)
  9. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
  10. Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. (PubMed id 14656967)1, 2 Xie T.... Hood L. (2003)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 8859 HGNC: 11398 AceView: STK19 Ensembl:ENSG00000204344 euGenes: HUgn8859
ECgene: STK19 H-InvDB: STK19

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for STK19 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for STK19 gene:
Search GeneIP for patents involving STK19

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