Aliases for STK16 Gene
External Ids for STK16 Gene
GeneCards Summary for STK16 Gene
STK16 (Serine/Threonine Kinase 16) is a Protein Coding gene. Diseases associated with STK16 include essential thrombocythemia and diffuse mesangial sclerosis. Among its related pathways are Sweet Taste Signaling. GO annotations related to this gene include protein serine/threonine kinase activity and non-membrane spanning protein tyrosine kinase activity.
UniProtKB/Swiss-Prot for STK16 Gene
Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.