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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

STEAP1 Gene

protein-coding   GIFtS: 56
GCID: GC07P089779

six transmembrane epithelial antigen of the prostate 1

(Previous name: six transmembrane epithelial antigen of the prostate )
(Previous symbol: STEAP)
 Explore 6 diseases affiliated with
STEAP1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for STEAP1    

Aliases
for STEAP1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Six Transmembrane Epithelial Antigen Of The Prostate 11 2     Six Transmembrane Epithelial Antigen Of The Prostate1
STEAP1 2 3 5     Metalloreductase STEAP12
PRSS241 2 3     EC 1.16.1.-3
Six-Transmembrane Epithelial Antigen Of Prostate 12 3     

External Ids:    HGNC: 113781   Entrez Gene: 268722   Ensembl: ENSG000001646477   OMIM: 6044155   UniProtKB: Q9UHE83   

Export aliases for STEAP1 gene to outside databases

Previous GC identifers: GC07P089430 GC07P089622 GC07P084394


Summaries
for STEAP1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for STEAP1:
This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines.
The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen
significantly expressed at cell-cell junctions. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: STEA1_HUMAN, Q9UHE8
Function: Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as
acceptor (By similarity)

Gene Wiki entry for STEAP1


Genomic Views
for STEAP1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.1  NT_007933.15  NT_079595.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the STEAP1 gene promoter:
         TBP   NRSF form 1   HTF   MyoD   NRSF form 2   NF-AT   C/EBPalpha   CREB   TFIID   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: STEAP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for STEAP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat STEAP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q21   Ensembl cytogenetic band:  7q21.13   HGNC cytogenetic band: 7q21

STEAP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
STEAP1 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P089779:  view genomic region     (about GC identifiers)

Start:
 89,783,689 bp from pter      End:
 89,794,143 bp from pter
Size:
 10,455 bases      Orientation:
 plus strand

1 alternative location:
Chr7+,CRA_TCAG 89,114,457-89,124,907     

Proteins
for STEAP1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: STEA1_HUMAN, Q9UHE8 (See protein sequence)
Recommended Name: Metalloreductase STEAP1  
Size: 339 amino acids; 39851 Da
Cofactor: FAD (By similarity)
Subcellular location: Endosome membrane; Multi-pass membrane protein (By similarity)
Secondary accessions: A4D1E0 O95034

Explore the universe of human proteins at neXtProt for STEAP1: NX_Q9UHE8

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9UHE8

    • STEAP1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_036581.1  
    ENSEMBL proteins: 
     ENSP00000297205   ENSP00000394402  

    Human Recombinant Protein Products: 
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    Novus Biologicals STEAP1 Proteins
    Novus Biologicals STEAP1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for STEAP1

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS10588738
    GO:0005887integral to plasma membrane TAS10588738
    GO:0005911cell-cell junction TAS10588738
    GO:0010008endosome membrane IEA--


    STEAP1 for ontologies           About GeneDecksing



    STEAP1 Antibody Products: 
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    Uscn ELISAs and CLIAs for STEAP1

    Protein Domains /
    Families
    for STEAP1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    STEAP1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR013130 Fe3_Rdtase_TM_dom

    Graphical View of Domain Structure for InterPro Entry Q9UHE8

    ProtoNet protein and cluster: Q9UHE8

    UniProtKB/Swiss-Prot: STEA1_HUMAN, Q9UHE8
    Similarity: Belongs to the STEAP family
    Similarity: Contains 1 ferric oxidoreductase domain


    Function
    for STEAP1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: STEA1_HUMAN, Q9UHE8
    Function: Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as
    acceptor (By similarity)

    Enzyme Number (IUBMB): EC 1.16.1.-1

    miRNA
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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate STEAP1:
    hsa-miR-203 hsa-miR-16-2* hsa-miR-195*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for STEAP1 (see all 7)
    OriGene shRNA RFP: STEAP1
    OriGene siRNA: STEAP1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat STEAP1

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for STEAP1

    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for STEAP1

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STEAP1

    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215transporter activity TAS10588738
    GO:0015267channel activity TAS10588738
    GO:0016491oxidoreductase activity IEA--
    GO:0046872metal ion binding IEA--


    STEAP1 for ontologies           About GeneDecksing



    Pathways & Interactions
    for STEAP1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Mineral absorption
    		Mineral absorption1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways



    1         Kegg Pathway  (Kegg details for STEAP1):
        Mineral absorption


    STEAP1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for STEAP1

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for STEAP1 (ENSP000002972054) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport ----
    GO:0006811ion transport IEA--
    GO:0022900electron transport chain IEA--
    GO:0055072iron ion homeostasis IEA--


    STEAP1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for STEAP1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for STEAP1

    3 HMDB Compounds for STEAP1    About this table
    CompoundSynonyms CAS #PubMed Ids
    FAD1H-Purin-6-amine flavin dinucleotide (see all 21)146-14-5--
    Heme(protoporphyrinato)iron (see all 19)14875-96-8--
    NAD3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)53-84-9--
    Search CenterWatch for drugs/clinical trials and news about STEAP1 / STEA1 

    Transcripts
    for STEAP1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for STEAP1 gene: 
    NM_012449.2  

    Unigene Cluster for STEAP1:

    Six transmembrane epithelial antigen of the prostate 1
    Hs.61635  [show with all ESTs]
    Unigene Representative Sequence: BF673939
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000297205(uc003ujx.3) ENST00000475789(uc010lem.3) ENST00000412573


    miRNA
    Products:             		 OriGene 3'-UTR Clone: STEAP1
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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate STEAP1:
    hsa-miR-203 hsa-miR-16-2* hsa-miR-195*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for STEAP1 (see all 7)
    OriGene shRNA RFP: STEAP1
    OriGene siRNA: STEAP1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat STEAP1
    Clone
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    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: STEAP1 (NM_012449)
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat STEAP1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat STEAP1

    Additional cDNA sequence: 

    AF186249.1 AK304076.1 AK308452.1 BC011802.2 

    7 DOTS entries:

    DT.442086  DT.75102235  DT.121114898  DT.100722967  DT.97781382  DT.100728980  DT.310260 

    24/55 AceView cDNA sequences (see all 55):

    BQ014747 BQ722891 AA888312 BM738424 BQ082502 NM_012449 CB049384 AF186249 
    BX476756 CA446381 BF003144 BC011802 CA488012 BI552907 BX103101 BM675259 
    AA316181 AI167942 BG104394 BM968995 CB119996 AI184070 CD677954 AI686139 

    GeneLoc Exon Structure


    Expression
    for STEAP1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    STEAP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GTTGGGAAGA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    STEAP1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Extraembryonic MesodermExtraembryonic Capillary PlexusExtraembryonic AngioblastsEndothelium
    Head MesenchymeBranchial Arch 1Cranial Neural Crest CellsNeural Crest
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 3 LifeMap Cells 
    NameCategory
    PureStem™ mesenchymal progenitor MEL2 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    PureStem™ progenitor E44 (Embryonic Progenitor Cell)
    PureStem™ progenitor F15 (Embryonic Progenitor Cell)

    See STEAP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for STEAP1

    SOURCE GeneReport for Unigene cluster: Hs.61635

    UniProtKB/Swiss-Prot: STEA1_HUMAN, Q9UHE8
    Tissue specificity: Ubiquitously expressed. Highly expressed in prostate tumors

        SABiosciences Expression via Pathway-Focused PCR Array including STEAP1: 
              Epithelial to Mesenchymal Transition (EMT) in human mouse rat

    Primer
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    In Situ
    Assay Products:     
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    Orthologs
    for STEAP1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for STEAP1 gene from 2/9 species (see all 9)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves STEAP11 six transmembrane epithelial antigen of the prostate more 71.8(n)
    66.16(a)    		   420540  XM_418642.2  XP_418642.2 
    lizard
    (Anolis carolinensis)    		 Reptilia --
    		 --
    		 68(a)
    		 1 → many
    		 6(20297925-20301959)


    ENSEMBL Gene Tree for STEAP1 (if available)
    TreeFam Gene Tree for STEAP1 (if available) 

    Paralogs
    for STEAP1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for STEAP1 gene
    STEAP22  STEAP1B2  STEAP42  STEAP32  
    6 SIMAP similar genes for STEAP1 using alignment to 2 protein entries:     STEA1_HUMAN (see all proteins):
    LOC392745    MGC87042    STEAP1B    STEAP2    STEAP3    STEAP4

    STEAP1 for paralogs           About GeneDecksing



    Genomic Variants
    for STEAP1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/241 NCBI SNPs in STEAP1 are shown (see all 241)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 7 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1851035801,2
    		--89781774(+) TAATTA/CGAAAA 1 -- us2k10--------
    rs281641,2
    		C,A,--89781826(+) CATATC/GAATAT 1 -- us2k14Minor allele frequency- G:0.01NA MN WA 270
    rs38577921,2
    		C,F,H,--89781950(+) TTTGTC/GTGACC 1 -- us2k1 tfbs312Minor allele frequency- G:0.35NS EA NA 528
    rs1878605841,2
    		--89782089(+) GTTTCA/TCTAGA 1 -- us2k10--------
    rs1915722121,2
    		--89782125(+) CACCAC/TAAGGT 1 -- us2k10--------
    rs102763141,2
    		--89782151(+) TTTAAC/GCTTCA 1 -- us2k1 tfbs30--------
    rs21902291,2
    		C--89782461(+) TAATTA/C/Taaaaa 1 -- us2k1 tfbs3 trp31NA 2
    rs1837145571,2
    		--89782517(+) TCTTCA/GGTGCC 1 -- us2k10--------
    rs1896773521,2
    		--89782528(+) CTAGCA/TGTGAA 1 -- us2k10--------
    rs1457063671,2
    		--89782555(+) AAAATA/GTGGTT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for STEAP1 (89783689 - 89794143 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for STEAP1
         2 CNVs: 2704 8573

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing STEAP1
    DNA2.0 Custom Variant and Variant Library Synthesis for STEAP1

    Disorders / Diseases
    for STEAP1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    STEAP1 for disorders           About GeneDecksing

    OMIM gene information: 604415    OMIM disorders: --

    6 diseases for STEAP1:    About MalaCards
    prostatitis    ewing's family of tumors    ovarian cancer    prostate cancer
    breast cancer    adenocarcinoma

    1 disease from the University of Copenhagen DISEASES database for STEAP1:
    Prostate cancer
    Human Genome Epidemiology (HuGE) Navigator: STEAP1 (2 documents)

    Export disorders for STEAP1 gene to outside databases

    Publications
    for STEAP1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for STEAP1 gene, integrated from 9 sources (see all 23):
    (articles sorted by number of sources associating them with STEAP1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. STEAP: a prostate-specific cell-surface antigen highly expressed in human prostate tumors. (PubMed id 10588738)1, 2, 9 Hubert R.S.... Afar D.E.H. (1999)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
    4. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
    5. Zoledronic acid decreases mRNA six-transmembrane epit helial antigen of prostate protein expression in prostate cancer cells. (PubMed id 19915386)1, 9 Valenti M.T....Dalle Carbonare L. (2010)
    6. Six-transmembrane epithelial antigen of the prostate (STEAP1 and STEAP2)-differentially expressed by murine and human mesenchymal st em cells. (PubMed id 19196137)1, 9 Vaghjiani R.J....Murphy C.L. (2009)
    7. STEAP1 is associated with the invasive and oxidative stress phenotype of Ewing tumors. (PubMed id 22080479)1 Grunewald T.G....Burdach S. (2012)
    8. High STEAP1 expression is associated with improved out come of Ewing's sarcoma patients. (PubMed id 22317770)1 Grunewald T.G....Burdach S. (2012)
    9. Activated human gd T cells induce peptide-specific CD8 + T-cell responses to tumor-associated self-antigens. (PubMed id 21928126)1 Altvater B....Rossig C. (2012)
    10. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)

    External Searches for STEAP1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing STEAP1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26872 HGNC: 11378 AceView: STEAP Ensembl:ENSG00000164647 euGenes: HUgn26872
    ECgene: STEAP1 Kegg: 26872 H-InvDB: STEAP1

    Other Databases showing STEAP1 gene

    (According to HUGE)
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    Specialized Databases showing STEAP1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for STEAP1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for STEAP1 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
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    Licensable technologies from WIS Yeda, Salk, Tufts,
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    		Patent Information for STEAP1 gene:
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