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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

STAU1 Gene

protein-coding   GIFtS: 55
GCID: GC20M047729

staufen, RNA binding protein, homolog 1 (Drosophila)

(Previous names: staufen (Drosophila, RNA-binding protein), staufen, RNA...)
(Previous symbol: STAU)
 Explore 6 diseases affiliated with
STAU1 via our new
 Human Malady Compendium 
Biological research products
for STAU1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Staufen, RNA Binding Protein, Homolog 1 (Drosophila)1 2
STAU1 2 3 5
Staufen (Drosophila, RNA-Binding Protein)1
Staufen, RNA Binding Protein (Drosophila)1
Double-Stranded RNA-Binding Protein Staufen Homolog 12

External Ids:    HGNC: 113701   Entrez Gene: 67802   Ensembl: ENSG000001242147   OMIM: 6017165   UniProtKB: O957933   

Export aliases for STAU1 gene to outside databases

Previous GC identifers: GC20M047164 GC20M044479


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for STAU1:
Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or
localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the
presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary
structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar
to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in
the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of
mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from
alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the
same isoform, however, differ in their 5'UTR. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: STAU1_HUMAN, O95793
Function: Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning
of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their
translation at the site

Gene Wiki entry for STAU1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NC_018931.1  NT_011362.10  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the STAU1 gene promoter:
         AML1a   Olf-1   LUN-1   RelA   POU6F1 (c2)   NF-kappaB   MEF-2A   Ik-2   aMEF-2   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSTAU1 promoter sequence
   Search SABiosciences Chromatin IP Primers for STAU1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat STAU1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.1   Ensembl cytogenetic band:  20q13.13   HGNC cytogenetic band: 20q13.1

STAU1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
STAU1 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M047729:  view genomic region     (about GC identifiers)

Start:
47,729,876 bp from pter      End:
47,804,904 bp from pter
Size:
75,029 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: STAU1_HUMAN, O95793 (See protein sequence)
Recommended Name: Double-stranded RNA-binding protein Staufen homolog 1  
Size: 577 amino acids; 63182 Da
Subunit: Binds tubulin. Binds with low affinity single-stranded RNA or DNA homopolymers. Interacts with CASC3 in an
RNA-dependent manner (By similarity). Identified in a mRNP complex, at least composed of DHX9, DDX3X, ELAVL1, HNRNPU,
IGF2BP1, ILF3, PABPC1, PCBP2, PTBP2, STAU1, STAU2, SYNCRIP and YBX1. Interacts with the influenza virus nonstructural
protein NS1
Subcellular location: Cytoplasm. Rough endoplasmic reticulum. Note=Localizes exclusively with the rough reticulum
endoplasmic (RER)
Secondary accessions: A8K9Z4 E1P5Y1 E1P608 Q5JW29 Q6GTM4 Q9H5B4 Q9H5B5 Q9Y3Q2
Alternative splicing: 3 isoforms:  O95793-1   O95793-2   O95793-3   

Explore the universe of human proteins at neXtProt for STAU1: NX_O95793

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O95793

  • STAU1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (5 alternative transcripts): 
    NP_001032405.1  NP_004593.2  NP_059346.2  NP_059347.2  NP_059348.2  

    ENSEMBL proteins: 
     ENSP00000360922   ENSP00000353604   ENSP00000323443   ENSP00000360870   ENSP00000360867  
     ENSP00000360857   ENSP00000416779   ENSP00000398785   ENSP00000360893   ENSP00000345425  

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    Uscn Proteins for STAU1

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005737cytoplasm IDA19029303
    GO:0005791rough endoplasmic reticulum IEA--
    GO:0005875microtubule associated complex TAS10022909
    GO:0010494cytoplasmic stress granule ISS--


    STAU1 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    STAU1 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR001159 Ds-RNA-bd
     IPR014720 dsRNA-bd-like_dom

    Graphical View of Domain Structure for InterPro Entry O95793

    ProtoNet protein and cluster: O95793

    1 Blocks protein family: IPB001159 Double-stranded RNA binding (DsRBD) domain

    UniProtKB/Swiss-Prot: STAU1_HUMAN, O95793
    Domain: One of the DRDB could be involved in RER binding
    Domain: The C-terminal contains the tubulin binding domain (TBD) (By similarity)
    Similarity: Contains 3 DRBM (double-stranded RNA-binding) domains


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: STAU1_HUMAN, O95793
    Function: Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning
    of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their
    translation at the site

         Genatlas biochemistry entry for STAU1:
    Drosophila Staufen homolog 1,involved,in mRNA transport and localization

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    hsa-miR-142-5p hsa-miR-142-3p hsa-miR-181c hsa-miR-3150a-3p hsa-miR-330-3p hsa-miR-1208 hsa-miR-181b hsa-miR-198
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding ----
    GO:0003725double-stranded RNA binding IEA--
    GO:0005515protein binding IPI15680326


    STAU1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for STAU1:
     Upregulation of Wnt/beta-caten 

    Animal Models:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Stau1):
     behavior/neurological  nervous system 

    STAU1 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for STAU1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/74 Interacting proteins for STAU1 (O957931, 2, 3 ENSP000003609224) via UniProtKB, MINT, STRING, and/or I2D (see all 74)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PPP1CAP621362, 3, ENSP000003260314MINT-62193 I2D: score=5 STRING: ENSP00000326031
    RPLP0P053881, 3, ENSP000003390274EBI-366174,EBI-354101 I2D: score=4 STRING: ENSP00000339027
    UPF1Q929001, 3, ENSP000002628034EBI-366174,EBI-373471 I2D: score=3 STRING: ENSP00000262803
    UBE2D3P610772, 3, ENSP000003497224MINT-8276152 I2D: score=2 STRING: ENSP00000349722
    CSNK2BP678702, 3MINT-8253649 I2D: score=2 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008298intracellular mRNA localization IEA--


    STAU1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for STAU1
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    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for STAU1 gene (5 alternative transcripts): 
    NM_001037328.1  NM_004602.2  NM_017452.2  NM_017453.2  NM_017454.2  

    Unigene Cluster for STAU1:

    Staufen, RNA binding protein, homolog 1 (Drosophila)
    Hs.596704  [show with all ESTs]
    Unigene Representative Sequence: NM_017453
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000371856(uc002xud.3 uc002xug.3) ENST00000360426 ENST00000347458
    ENST00000371805 ENST00000371802 ENST00000371792 ENST00000437404 ENST00000456866
    ENST00000371828(uc002xub.3 uc002xuf.3) ENST00000340954(uc002xua.3 uc002xuc.3 uc002xue.3)


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    hsa-miR-142-5p hsa-miR-142-3p hsa-miR-181c hsa-miR-3150a-3p hsa-miR-330-3p hsa-miR-1208 hsa-miR-181b hsa-miR-198
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    Additional cDNA sequence: 

    AB209561.1 AF061938.1 AF061939.1 AF061940.1 AF061941.1 AJ132258.1 AK025519.1 AK057739.1 
    AK091405.1 AK291487.1 AK292859.1 AK298372.1 AL136601.2 AY529074.1 AY546099.1 BC000830.1 
    BC001893.1 BC007532.1 BC010169.2 BC050432.1 BC095397.1 

    24/36 DOTS entries (see all 36):

    DT.92449625  DT.100827903  DT.418633  DT.95293366  DT.95325331  DT.100827909  DT.92449630  DT.101983819 
    DT.120795743  DT.120795675  DT.120795501  DT.100827898  DT.95243773  DT.100827899  DT.120795655  DT.100658186 
    DT.95184160  DT.100648489  DT.100827904  DT.100827905  DT.120795628  DT.120795694  DT.100827900  DT.120795585 

    24/454 AceView cDNA sequences (see all 454):

    BC001893 CB240978 AI687569 Z41528 AI383429 AA043331 BF447947 AW207234 
    BM141844 BU622917 CF541112 BX390983 BE328721 AA043332 BU158599 AW105669 
    BM142141 AW166420 BU194741 AA903609 CF594111 AI802592 BE348298 BM542783 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for STAU1 (see all 11)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d ^ 9 ^ 10 ^ 11a · 11b · 11c ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b
    SP1:        -     -     -                 -     -                                         -                       -                                             
    SP2:                    -                 -     -                                         -                       -                                             
    SP3:                    -           -     -     -                                                                 -                                             
    SP4:                    -           -     -     -                                         -                       -                                             
    SP5:                                -     -     -                                                                                                               


    ECgene alternative splicing isoforms for STAU1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    STAU1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GAATGTAAGT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See STAU1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for STAU1

    SOURCE GeneReport for Unigene cluster: Hs.596704

    UniProtKB/Swiss-Prot: STAU1_HUMAN, O95793
    Tissue specificity: Widely expressed. Expressed in brain, pancreas, heart, skeletal muscles, liver, lung, kidney and
    placenta

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for STAU1 gene from 6/18 species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves STAU11 staufen, RNA binding protein, homolog 1 (Drosophila) 81.68(n)
    90.28(a)
      419213  NM_001012831.1  NP_001012849.1 
    lizard
    (Anolis carolinensis)
    Reptilia STAU16
    --
    65(a)
    1 ↔ 1
    4(146429616-146453270)
    African clawed frog
    (Xenopus laevis)
    Amphibia LOC3989372 hypothetical protein LOC398937 78.88(n)    BC060382.1 
    zebrafish
    (Danio rerio)
    Actinopterygii stau11 staufen, RNA binding protein, homolog 1 (Drosophila) 70.05(n)
    75.75(a)
      334440  NM_205561.1  NP_991124.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta stau6
    staufen
    17(a)
    1 → many
    2R(14005401-14013337)
    worm
    (Caenorhabditis elegans)
    Secernentea stau-16
    STAUfen (dsRNA binding protein) homolog family mem...
    20(a)
    1 → many
    X(1027668-1035241)


    ENSEMBL Gene Tree for STAU1 (if available)
    TreeFam Gene Tree for STAU1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for STAU1 gene
    TARBP22  STAU22  PRKRA2  
    3 SIMAP similar genes for STAU1 using alignment to 5 protein entries:     STAU1_HUMAN (see all proteins):
    STAU2    STAU2 variant protein    TARBP2

    STAU1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for STAU1
    PGOHUM00000234180


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1428 NCBI SNPs in STAU1 are shown (see all 1428    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1390018401,2
    --47729491(+) TTCAGC/TTATTC 5 -- ds50010--------
    rs1498843001,2
    --47729530(+) AGTGAA/CGCCTT 5 -- ds50010--------
    rs1829934421,2
    --47729555(+) ACTTCC/TTCTAA 5 -- ds50010--------
    rs1465024771,2
    --47729640(+) GGTGAA/GAGATG 5 -- ds50010--------
    rs1131088031,2
    --47729709(+) GGTAGC/TAATGT 5 -- ds50012Minor allele frequency- T:0.03CSA WA 120
    rs1878864481,2
    --47729790(+) GAGGGA/GCTGGC 5 -- ds50010--------
    rs1447965091,2
    --47729849(+) ATTTT-/AAGTTA 5 -- ds50010--------
    rs1913047431,2
    --47729918(+) AAAGTA/TATTTC 5 -- ut310--------
    rs2005606811,2
    C--47729968(+) ACAAAA/GTTTTT 5 -- ut310--------
    rs30923351,2
    C,F,--47729969(+) CAAAG-/TTTTTT 5 -- ut31 trp33Minor allele frequency- T:0.33NA CSA 6

    HapMap Linkage Disequilibrium report for STAU1 (47729876 - 47804904 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for STAU1
         1 CNV: 22989

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    STAU1 for disorders           About GeneDecksing

    OMIM gene information: 601716    OMIM disorders: --

    6 diseases for STAU1:    About MalaCards
    metastasis efficiency    influenza    prostate cancer    prostatitis
    immunodeficiency    neuronitis


    Export disorders for STAU1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for STAU1 gene, integrated from 9 sources (see all 64):
    (articles sorted by number of sources associating them with STAU1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay. (PubMed id 15680326)1, 3, 9 Kim Y.K....Maquat L.E. (2005)
    2. Localization of a human double-stranded RNA-binding protein gene (STAU) to band 20q13.1 by fluorescence in situ hybridization. (PubMed id 8884277)1, 3, 9 DesGroseillers L. and Lemieux N. (1996)
    3. Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs. (PubMed id 19029303)1, 2 Weidensdorfer D....HA1ttelmaier S. (2009)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    7. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    8. Interaction of influenza virus NS1 protein and the human homologue of Staufen in vivo and in vitro. (PubMed id 10325410)1, 2 Falcon A.M.... Ortin J. (1999)
    9. Mammalian Staufen is a double-stranded-RNA- and tubulin-binding protein which localizes to the rough endoplasmic reticulum. (PubMed id 10022909)1, 2 Wickham L.... DesGroseillers L. (1999)
    10. The host protein Staufen1 interacts with the Pr55Gag zinc fingers and regulates HIV-1 assembly via its N-terminus. (PubMed id 18498651)1, 9 Chatel-Chaix L....Desgroseillers L. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6780 HGNC: 11370 AceView: STAU Ensembl:ENSG00000124214 euGenes: HUgn6780
    ECgene: STAU1 H-InvDB: STAU1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for STAU1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for STAU1 gene:
    Search GeneIP for patents involving STAU1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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