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Aliases for STARD9 Gene

Aliases for STARD9 Gene

  • StAR-Related Lipid Transfer (START) Domain Containing 9 2 3
  • START Domain-Containing Protein 9 3 4
  • START Domain Containing 9 2 3
  • KIAA1300 4 6
  • StAR-Related Lipid Transfer Protein 9 3
  • KIF16A 3
  • StARD9 4

External Ids for STARD9 Gene

Summaries for STARD9 Gene

GeneCards Summary for STARD9 Gene

STARD9 (StAR-Related Lipid Transfer (START) Domain Containing 9) is a Protein Coding gene. GO annotations related to this gene include microtubule binding and microtubule motor activity. An important paralog of this gene is KIF14.

UniProtKB/Swiss-Prot for STARD9 Gene

  • Microtubule-dependent motor protein required for spindle pole assembly during mitosis. Required to stabilize the pericentriolar material (PCM).

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for STARD9 Gene

Genomics for STARD9 Gene

Genomic Location for STARD9 Gene

Start:
42,575,634 bp from pter
End:
42,720,998 bp from pter
Size:
145,365 bases
Orientation:
Plus strand

Genomic View for STARD9 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for STARD9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for STARD9 Gene

Regulatory Elements for STARD9 Gene

Proteins for STARD9 Gene

  • Protein details for STARD9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9P2P6-STAR9_HUMAN
    Recommended name:
    StAR-related lipid transfer protein 9
    Protein Accession:
    Q9P2P6
    Secondary Accessions:
    • Q68DG2
    • Q6AI01
    • Q6ZWK0
    • Q9UF70

    Protein attributes for STARD9 Gene

    Size:
    4700 amino acids
    Molecular mass:
    516343 Da
    Quaternary structure:
    • Interacts with ATAD3A.
    SequenceCaution:
    • Sequence=CAH18258.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAH18258.1; Type=Erroneous termination; Positions=2903; Note=Translated as Gln.; Evidence={ECO:0000305};

    Alternative splice isoforms for STARD9 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for STARD9 Gene

Proteomics data for STARD9 Gene at MOPED

Post-translational modifications for STARD9 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for STARD9 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for STARD9 Gene

Domains for STARD9 Gene

Gene Families for STARD9 Gene

HGNC:
  • StARD :StAR-related lipid transfer (START) domain containing

UniProtKB/Swiss-Prot:

STAR9_HUMAN
Domain:
  • Contains 1 FHA domain.:
    • Q9P2P6
  • Contains 1 kinesin motor domain.:
    • Q9P2P6
  • Contains 1 START domain.:
    • Q9P2P6
Family:
  • Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.:
    • Q9P2P6
genes like me logo Genes that share domains with STARD9: view

Function for STARD9 Gene

Molecular function for STARD9 Gene

UniProtKB/Swiss-Prot Function: Microtubule-dependent motor protein required for spindle pole assembly during mitosis. Required to stabilize the pericentriolar material (PCM).

Gene Ontology (GO) - Molecular Function for STARD9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003777 microtubule motor activity IDA 22153075
GO:0005515 protein binding --
GO:0005524 ATP binding IEA --
GO:0008017 microtubule binding IDA 22153075
GO:0008289 lipid binding IEA --
genes like me logo Genes that share ontologies with STARD9: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for STARD9 Gene

Localization for STARD9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for STARD9 Gene

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Nucleus. Note=Localizes throughout the cytoplasm and nucleus during interphase. Localizes to the daughter centriole during mitosis. Disappears in cytokinesis.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for STARD9 Gene COMPARTMENTS Subcellular localization image for STARD9 gene
Compartment Confidence
cytoskeleton 5
nucleus 5
cytosol 3
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for STARD9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA 22153075
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IDA --
GO:0005794 Golgi apparatus IDA --
GO:0005814 centriole IDA 22153075
genes like me logo Genes that share ontologies with STARD9: view

Pathways for STARD9 Gene

SuperPathways for STARD9 Gene

No Data Available

Interacting Proteins for STARD9 Gene

Gene Ontology (GO) - Biological Process for STARD9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006200 obsolete ATP catabolic process --
GO:0007018 microtubule-based movement IBA --
GO:0008152 metabolic process IDA 22153075
GO:0051225 spindle assembly IMP 22153075
genes like me logo Genes that share ontologies with STARD9: view

No data available for Pathways by source for STARD9 Gene

Transcripts for STARD9 Gene

mRNA/cDNA for STARD9 Gene

(11) REFSEQ mRNAs :
(10) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for STARD9 Gene

StAR-related lipid transfer (START) domain containing 9:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for STARD9 Gene

No ASD Table

Relevant External Links for STARD9 Gene

GeneLoc Exon Structure for
STARD9
ECgene alternative splicing isoforms for
STARD9

Expression for STARD9 Gene

mRNA expression in normal human tissues for STARD9 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for STARD9 Gene

SOURCE GeneReport for Unigene cluster for STARD9 Gene Hs.122061

mRNA Expression by UniProt/SwissProt for STARD9 Gene

Q9P2P6-STAR9_HUMAN
Tissue specificity: Expressed in the central nervous system, muscle cells (heart and skeletal muscle), pancreas, prostate and lung.
genes like me logo Genes that share expressions with STARD9: view

Orthologs for STARD9 Gene

This gene was present in the common ancestor of animals.

Orthologs for STARD9 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia STARD9 36
  • 99.29 (n)
  • 98.72 (a)
STARD9 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 63 (a)
OneToMany
-- 37
  • 65 (a)
OneToMany
STARD9 36
  • 75.95 (n)
  • 63.27 (a)
dog
(Canis familiaris)
Mammalia STARD9 36
  • 80.16 (n)
  • 68.88 (a)
STARD9 37
  • 68 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Stard9 36
  • 73.73 (n)
  • 60.94 (a)
Stard9 37
  • 60 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia STARD9 37
  • 37 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 29 (a)
ManyToMany
chicken
(Gallus gallus)
Aves STARD9 37
  • 34 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia STARD9 37
  • 33 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii stard9 37
  • 31 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta unc-104 37
  • 24 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea unc-104 37
  • 24 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 20 (a)
OneToMany
Species with no ortholog for STARD9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for STARD9 Gene

ENSEMBL:
Gene Tree for STARD9 (if available)
TreeFam:
Gene Tree for STARD9 (if available)

Paralogs for STARD9 Gene

Paralogs for STARD9 Gene

Selected SIMAP similar genes for STARD9 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with STARD9: view

Variants for STARD9 Gene

Sequence variations from dbSNP and Humsavar for STARD9 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs9269 -- 42,720,076(+) TTTAA(A/G)AAACA utr-variant-3-prime
rs479519 -- 42,600,611(-) gaggc(A/G)gaggt intron-variant
rs537731 -- 42,625,617(-) gcatg(C/G)gggct intron-variant
rs565298 -- 42,600,994(+) gtttt(A/C)ctagg intron-variant
rs623271 -- 42,636,010(+) TGGTC(A/G)GGGTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for STARD9 Gene

Variant ID Type Subtype PubMed ID
nsv528725 CNV Gain 19592680
esv2749624 CNV Deletion 23290073
nsv1509 CNV Insertion 18451855
esv2657104 CNV Deletion 23128226
nsv457122 CNV Loss 19166990
nsv517553 CNV Gain+Loss 19592680
esv2662746 CNV Deletion 23128226
esv25347 CNV Loss 19812545
esv1651282 CNV Insertion 17803354

Relevant External Links for STARD9 Gene

HapMap Linkage Disequilibrium report
STARD9

Disorders for STARD9 Gene

Relevant External Links for STARD9

Genetic Association Database (GAD)
STARD9
Human Genome Epidemiology (HuGE) Navigator
STARD9
genes like me logo Genes that share disorders with STARD9: view

No data available for UniProtKB/Swiss-Prot for STARD9 Gene

Publications for STARD9 Gene

  1. Identification and characterization of the human StARD9 gene in the LGMD2A-region on chromosome 15q15 by in silico methods. (PMID: 16964419) Halama N. … Jager D. (Int. J. Mol. Med. 2006) 3 4 23
  2. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10718198) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4
  3. A genome-wide association study identifies protein quantitative trait loci (pQTLs). (PMID: 18464913) Melzer D. … Ferrucci L. (PLoS Genet. 2008) 3 49
  4. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 49
  5. The STARD9/Kif16a kinesin associates with mitotic microtubules and regulates spindle pole assembly. (PMID: 22153075) Torres J.Z. … Jackson P.K. (Cell 2011) 3 4

Products for STARD9 Gene

Sources for STARD9 Gene

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