STARD8 Gene

Aliases
for STARD8 gene

Previous GC identifers: GC0XP064091 GC0XP065390 GC0XP066100 GC0XP066734 GC0XP067650 GC0XP067784 GC0XP061695

Summaries
for STARD8 gene

Genomic Views
for STARD8 gene

RefSeq DNA sequence:

NC_000023.10  NC_018934.1  NT_011669.17  

SwitchGear Promoter luciferase reporter plasmid: STARD8 promoter sequence

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat STARD8

STARD8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP067867:  view genomic region     (about GC identifiers)

Proteins
for STARD8 gene

Explore the universe of human proteins at neXtProt for STARD8: NX_Q92502

Post-translational modifications:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate: STARD8 OriGene Custom Protein Services for STARD8
	GenScript Custom Purified and Recombinant Proteins Services for STARD8
	Novus Biologicals STARD8 Protein Novus Biologicals STARD8 Lysates
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for STARD8

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for STARD8
	GenScript Custom Superior Antibodies Services for STARD8
	Novus Biologicals STARD8 Antibodies
	Search for Antibodies for STARD8 at Abcam
	Uscn Antibodies for STARD8
	Search ThermoFisher Antibodies for STARD8

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for STARD8
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for STARD8

Protein Domains /
Families
for STARD8 gene

ProtoNet protein and cluster: Q92502

Function
for STARD8 gene

miRNA Products:		OriGene 3'-UTR Clone (see all 3): STARD8 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat STARD8
		8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate STARD8 (see all 9):
		hsa-miR-185* hsa-miR-16-1* hsa-let-7a-2* hsa-miR-548s hsa-miR-3926 hsa-miR-144 hsa-let-7g* hsa-miR-101
		SwitchGear 3'UTR luciferase reporter plasmid: STARD8 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for STARD8 (see all 7) OriGene shRNA RFP: STARD8 OriGene siRNA: STARD8
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat STARD8

Gene Editing Products:

DNA2.0 Custom Protein Engineering Service for STARD8

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for STARD8 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for STARD8 (see all 4) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 3): STARD8 (NM_001142504)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for STARD8
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat STARD8

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for STARD8
		Search LifeMap BioReagents cell lines for STARD8

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STARD8

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

Pathways & Interactions
for STARD8 gene

	Super-pathway	contained gene-specific pathways
1	Cell death signalling via NRAGE, NRIF and NADE	Signaling by Rho GTPases 0.25 Rho GTPase cycle 0.25
2	Signaling by GPCR	Signal Transduction 0.56

3        Reactome Pathways for STARD8

	Signaling by Rho GTPases
	Signal Transduction
	Rho GTPase cycle

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

Drugs & Compounds
for STARD8 gene

Transcripts
for STARD8 gene

Expression
for STARD8 gene

STARD8 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

Stem Cell Differentiation: 6 LifeMap Cells
	Name			Category
	PureStem™ endothelial progenitor 30-MV2-12 (Embryonic Progenitor Cell)			Blood, Endothelium
	PureStem™ endothelial Progenitor 30-SM2-3 (Embryonic Progenitor Cell)			Blood, Endothelium
	PureStem™ mesenchymal progenitor SM30 (Embryonic Progenitor Cell)			Adipose, Bone, Cartilage
	PureStem™ progenitor W10 (Embryonic Progenitor Cell)
	PureStem™ progenitor Z1 (Embryonic Progenitor Cell)
	Extraembryonic endoderm-like cells (Generation of extrae...)
Expression: Positive    Negative     Selective marker Experimental details: Curated     Microarrays     In-situ hybridization

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for STARD8 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT2 qPCR Primer Assay in human, mouse, rat STARD8
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat STARD8
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat STARD8

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STARD8

Orthologs
for STARD8 gene

Paralogs
for STARD8 gene

Paralogs for STARD8 gene

ARHGAP36²  ARHGAP6²  STARD13²  ARHGAP40²  ARHGAP18²  ARHGAP11A²  DLC1²  ARHGAP28²  

ARHGAP11B²  

2 SIMAP similar genes for STARD8 using alignment to 2 protein entries:     STAR8_HUMAN (see all proteins):

DLC1    STARD13

STARD8 for paralogs           About GeneDecksing

Genomic Variants
for STARD8 gene

10/1020 NCBI SNPs in STARD8 are shown (see all 1020)     About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr X pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs1474149101,2		--	67865584(+)	AGGCCC/TAAGGT	2	--	us2k1		0	--	--	--	--
rs78843921,2	A,H	--	67865694(+)	CAGAAT/CTGAAA	2	--	us2k1 tfbs3		4		NS EA	418
rs1391444331,2		--	67865740(+)	GCTGCA/GCACTA	2	--	us2k1		0	--	--	--	--
rs1495434171,2		--	67865805(+)	TGGAAC/TGGAAA	2	--	us2k1		0	--	--	--	--
rs1872642881,2		--	67865908(+)	CCTCAC/GGTCTC	2	--	us2k1		0	--	--	--	--
rs78846781,2	A	--	67865910(+)	TCAGGC/TCTCTG	2	--	us2k1		0	--	--	--	--
rs1441606211,2		--	67865976(+)	TCCTCA/GTGTTA	2	--	us2k1		0	--	--	--	--
rs1901739011,2		--	67866001(+)	GCAGAA/GGGCTT	2	--	us2k1		0	--	--	--	--
rs78797851,2	C,A,H	--	67866002(+)	CAGAGG/AGCTTC	2	--	us2k1		4		NS EA	418
rs78807631,2	C,A,H	--	67866034(+)	CTGGAC/GGTGGG	2	--	us2k1		4		NS EA	412

HapMap Linkage Disequilibrium report for STARD8 (67867508 - 67945684 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for STARD8
     3 CNVs: 53025 53024 53026
Locus Specific Mutation Databases (LSDB): STARD8

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing STARD8

DNA2.0 Custom Variant and Variant Library Synthesis for STARD8

Disorders / Diseases
for STARD8 gene

Publications
for STARD8 gene

PubMed articles for STARD8 gene, integrated from 9 sources (see all 13): (articles sorted by number of sources associating them with STARD8)

Utopia: connect your pdf to the dynamic world of online information

1. Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 8724849)^{1, 2, 3} Nagase T.... Nomura N. (1996)
2. Oncogenic inhibition by a deleted in liver cancer gene requires cooperation between tensin binding and Rho-specific GTPase-activating protein activities. (PubMed id 17517630)^{1, 2} Qian X....Lowy D.R. (2007)
3. START-GAP3/DLC3 is a GAP for RhoA and Cdc42 and is localized in focal adhesions regulating cell morphology. (PubMed id 17976533)^{1, 2} Kawai K.... Yagisawa H. (2007)
4. Deleted in liver cancer 3 (DLC-3), a novel Rho GTPase-activating protein, is downregulated in cancer and inhibits tumor cell growth. (PubMed id 17297465)^{1, 2} Durkin M.E.... Popescu N.C. (2007)
5. The DNA sequence of the human X chromosome. (PubMed id 15772651)^{1, 2} Ross M.T.... Bentley D.R. (2005)
6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
7. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)¹ Bailey S.D....Anand S. (2010)
8. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)¹ Talmud P.J.... . (2009)
9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
10. The origin of EFNB1 mutations in craniofrontonasal syndrome: frequent somatic mosaicism and explanation of the paucity of carrier males. (PubMed id 16685650)¹ Twigg S.R....Wilkie A.O. (2006)

External Searches for STARD8 gene

Genome Databases showing STARD8 gene

Other Databases showing STARD8 gene

Specialized Databases showing STARD8 gene

Products
for STARD8 gene