Aliases for STARD8 Gene
External Ids for STARD8 Gene
Previous GeneCards Identifiers for STARD8 Gene
This gene encodes a member of a subfamily of Rho GTPase activating proteins that contain a steroidogenic acute regulatory protein related lipid transfer domain. The encoded protein localizes to focal adhesions and may be involved in regulating cell morphology. This protein may also function as a tumor suppressor. [provided by RefSeq, Mar 2010]
GeneCards Summary for STARD8 Gene
STARD8 (StAR-Related Lipid Transfer (START) Domain Containing 8) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Rho GTPase cycle. GO annotations related to this gene include GTPase activator activity. An important paralog of this gene is ARHGAP11A.
UniProtKB/Swiss-Prot for STARD8 Gene
Accelerates GTPase activity of RHOA and CDC42, but not RAC1. Stimulates the hydrolysis of phosphatidylinositol 4,5-bisphosphate by PLCD1.