Aliases for STARD8 Gene
External Ids for STARD8 Gene
Previous GeneCards Identifiers for STARD8 Gene
This gene encodes a member of a subfamily of Rho GTPase activating proteins that contain a steroidogenic acute regulatory protein related lipid transfer domain. The encoded protein localizes to focal adhesions and may be involved in regulating cell morphology. This protein may also function as a tumor suppressor. [provided by RefSeq, Mar 2010]
GeneCards Summary for STARD8 Gene
STARD8 (StAR Related Lipid Transfer Domain Containing 8) is a Protein Coding gene. Among its related pathways are p75 NTR receptor-mediated signalling and Signaling by Rho GTPases. GO annotations related to this gene include GTPase activator activity and lipid binding. An important paralog of this gene is STARD13.
UniProtKB/Swiss-Prot for STARD8 Gene
Accelerates GTPase activity of RHOA and CDC42, but not RAC1. Stimulates the hydrolysis of phosphatidylinositol 4,5-bisphosphate by PLCD1.