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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

STARD8 Gene

protein-coding   GIFtS: 56
GCID: GC0XP067867

StAR-Related Lipid Transfer (START) Domain Containing 8

(Previous name: START domain containing 8)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
StAR-Related Lipid Transfer (START) Domain Containing 81 2     ARHGAP382
DLC32 3 5     StAR-Related Lipid Transfer Protein 82
START Domain Containing 81 2     DLC-33
Deleted In Liver Cancer 3 Protein2 3     START-GAP33
STARTGAP32 5     StARD83
KIAA01893 5     START Domain-Containing Protein 83

External Ids:    HGNC: 191611   Entrez Gene: 97542   Ensembl: ENSG000001300527   OMIM: 3006895   UniProtKB: Q925023   

Export aliases for STARD8 gene to outside databases

Previous GC identifers: GC0XP064091 GC0XP065390 GC0XP066100 GC0XP066734 GC0XP067650 GC0XP067784 GC0XP061695


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for STARD8 Gene:
This gene encodes a member of a subfamily of Rho GTPase activating proteins that contain a steroidogenic acute
regulatory protein related lipid transfer domain. The encoded protein localizes to focal adhesions and may be
involved in regulating cell morphology. This protein may also function as a tumor suppressor. (provided by
RefSeq, Mar 2010)

GeneCards Summary for STARD8 Gene: 
STARD8 (StAR-related lipid transfer (START) domain containing 8) is a protein-coding gene. Diseases associated with STARD8 include craniofrontonasal syndrome, and among its related super-pathways are Signaling by Rho GTPases and Signaling by GPCR. GO annotations related to this gene include GTPase activator activity. An important paralog of this gene is STARD13.

UniProtKB/Swiss-Prot: STAR8_HUMAN, Q92502
Function: Accelerates GTPase activity of RHOA and CDC42, but not RAC1. Stimulates the hydrolysis of
phosphatidylinositol 4,5-bisphosphate by PLCD1

Gene Wiki entry for STARD8 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NT_011669.17  NC_018934.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the STARD8 gene promoter:
         SRF   FOXF2   Brachyury   SRF (504 AA)   HSF1 (long)   Ik-3   PPAR-gamma1   Ik-2   HSF1short   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSTARD8 promoter sequence
   Search SABiosciences Chromatin IP Primers for STARD8

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat STARD8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq13.1   Ensembl cytogenetic band:  Xq13.1   HGNC cytogenetic band: Xq13.1

STARD8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
STARD8 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP067867:  view genomic region     (about GC identifiers)

Start:
67,867,508 bp from pter      End:
67,945,684 bp from pter
Size:
78,177 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: STAR8_HUMAN, Q92502 (See protein sequence)
Recommended Name: StAR-related lipid transfer protein 8  
Size: 1023 amino acids; 112601 Da
Subunit: Binds both the SH2 and PTB domains of TNS1
Subcellular location: Cell junction, focal adhesion
Sequence caution: Sequence=BAA11506.2; Type=Erroneous initiation;
Secondary accessions: A8K6T2 D3DVT9 Q5JST0 Q68DG7
Alternative splicing: 2 isoforms:  Q92502-1   Q92502-2   (Ref.3 (CAH18253) sequence is in conflict in position: 71:D->G. No experimental confirmation available)

Explore the universe of human proteins at neXtProt for STARD8: NX_Q92502

Explore proteomics data for STARD8 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q92502

  • STARD8 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    STARD8 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001135975.1  NP_001135976.1  NP_055540.2  

    ENSEMBL proteins: 
     ENSP00000428031   ENSP00000363727   ENSP00000363725   ENSP00000252336  
    Reactome Protein details: Q92502
    Human Recombinant Protein Products for STARD8: 
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    Novus Biologicals STARD8 Protein
    Novus Biologicals STARD8 Lysates
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for STARD8 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005829cytosol TAS--
    GO:0005925focal adhesion IEA--

    STARD8 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    StARD: StAR-related lipid transfer (START) domain containing
    ARHGAP: Rho GTPase activating proteins

    4 InterPro protein domains:
     IPR023393 START-like_dom
     IPR008936 Rho_GTPase_activation_prot
     IPR002913 START_lipid-bd_dom
     IPR000198 RhoGAP_dom

    Graphical View of Domain Structure for InterPro Entry Q92502

    ProtoNet protein and cluster: Q92502

    2 Blocks protein domains:
    IPB000198 RhoGAP domain
    IPB002913 Lipid-binding START


    UniProtKB/Swiss-Prot: STAR8_HUMAN, Q92502
    Similarity: Contains 1 Rho-GAP domain
    Similarity: Contains 1 START domain


    STARD8 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: STAR8_HUMAN, Q92502
    Function: Accelerates GTPase activity of RHOA and CDC42, but not RAC1. Stimulates the hydrolysis of
    phosphatidylinositol 4,5-bisphosphate by PLCD1

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005096GTPase activator activity IEA--
         
    STARD8 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for STARD8:
     Upregulation of Wnt/beta-caten 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for STARD8 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for STARD8

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for STARD8 
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    miRNA
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    hsa-miR-185* hsa-miR-16-1* hsa-let-7a-2* hsa-miR-548s hsa-miR-3926 hsa-miR-144 hsa-let-7g* hsa-miR-101
    SwitchGear 3'UTR luciferase reporter plasmidSTARD8 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for STARD8 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Rho GTPase cycle
    Rho GTPase cycle1.00
    Signaling by Rho GTPases1.00
    2Signaling by GPCR
    Signal Transduction0.55

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3        Reactome Pathways for STARD8
        Signaling by Rho GTPases
    Signal Transduction
    Rho GTPase cycle



    STARD8 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for STARD8

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/34 Interacting proteins for STARD8 (ENSP000003637274) via UniProtKB, MINT, STRING, and/or I2D (see all 34)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARHGAP4ENSP000002037864STRING: ENSP00000203786
    ARHGEF6ENSP000002506174STRING: ENSP00000250617
    ARHGEF9ENSP000002534014STRING: ENSP00000253401
    FGD1ENSP000003642774STRING: ENSP00000364277
    RHOUENSP000003556524STRING: ENSP00000355652
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction ----
    GO:0007264small GTPase mediated signal transduction TAS--
    GO:0051056regulation of small GTPase mediated signal transduction TAS--

    STARD8 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for STARD8 (STAR8)

    Search CenterWatch for drugs/clinical trials and news about STARD8 / STAR8

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for STARD8 gene (3 alternative transcripts): 
    NM_001142503.2  NM_001142504.2  NM_014725.4  

    Unigene Cluster for STARD8:

    StAR-related lipid transfer (START) domain containing 8
    Hs.95140  [show with all ESTs]
    Unigene Representative Sequence: NM_001142503
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000488088 ENST00000523864(uc004dxb.3 uc004dxa.3) ENST00000374599
    ENST00000374597(uc004dxc.4) ENST00000252336
    miRNA
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    8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate STARD8 (see all 9):
    hsa-miR-185* hsa-miR-16-1* hsa-let-7a-2* hsa-miR-548s hsa-miR-3926 hsa-miR-144 hsa-let-7g* hsa-miR-101
    SwitchGear 3'UTR luciferase reporter plasmidSTARD8 3' UTR sequence
    Inhib. RNA
    Products:
         
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat STARD8
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat STARD8

    Additional mRNA sequence: 

    AK291747.1 BC035587.1 CR749411.1 D80011.1 

    4 DOTS entries:

    DT.405776  DT.99968796  DT.100670258  DT.100754990 

    24/32 AceView cDNA sequences (see all 32):

    BX102921 BC035587 CD365748 CR749411 D80011 BM463579 CA390286 AI880296 
    CD519156 CD558954 NM_014725 BX398261 BX504204 BX397171 BX327875 BI769131 
    CD626005 BX458684 BX390445 CD626008 BI114834 BQ723269 AA027138 AI752271 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for STARD8 (see all 8)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d · 8e · 8f ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16
    SP1:                    -     -     -                       -     -     -     -     -     -     -                                             
    SP2:              -     -     -     -                                                                                                         
    SP3:                                                        -                                                                                 
    SP4:                                                                                                                                          
    SP5:                                                        -                                                                                 


    ECgene alternative splicing isoforms for STARD8

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    STARD8 expression in normal human tissues (normalized intensities)      STARD8 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    STARD8 Expression
    About this image


    STARD8 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Brain (Nervous System)
             Cerebral Cortex
     
     Placenta (Extraembryonic Tissues)

    See STARD8 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for STARD8

    SOURCE GeneReport for Unigene cluster: Hs.95140

    UniProtKB/Swiss-Prot: STAR8_HUMAN, Q92502
    Tissue specificity: Widely expressed with highest levels in kidney, lung and placenta

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STARD8

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for STARD8 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Stard81 , 5 START domain containing 81, 5 84.9(n)1
    86.65(a)1
      X (43.19 cM)5
    2369201  NM_199018.21  NP_950183.11 
     990032485 
    chicken
    (Gallus gallus)
    Aves STARD81 START domain containing 8 68.59(n)
    64.94(a)
      768976  XM_001232149.2  XP_001232150.2 
    lizard
    (Anolis carolinensis)
    Reptilia STARD86
    StAR-related lipid transfer (START) domain contain...
    59(a)
    1 ↔ 1
    GL343465.1(57718-75842)
    zebrafish
    (Danio rerio)
    Actinopterygii stard81 StAR-related lipid transfer (START) domain containing more 57.99(n)
    57.07(a)
      558476  NM_001126477.1  NP_001119949.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta cv-c6
    crossveinless c
    13(a)
    1 → many
    3R(10217402-10307410)
    worm
    (Caenorhabditis elegans)
    Secernentea gei-16
    Protein GEI-1, isoform a
    17(a)
    1 → many
    III(3344875-3363427)


    ENSEMBL Gene Tree for STARD8 (if available)
    TreeFam Gene Tree for STARD8 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for STARD8 gene
    STARD132  ARHGAP362  ARHGAP62  ARHGAP402  ARHGAP182  DLC12  ARHGAP11A2  ARHGAP282  
    ARHGAP11B2  
    2 SIMAP similar genes for STARD8 using alignment to 2 protein entries:     STAR8_HUMAN (see all proteins):
    STARD13    DLC1

    STARD8 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1256 SNPs in STARD8 are shown (see all 1256)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0365884
    A breast cancer sample4--see VAR_0365882 G S mis40--------
    VAR_0365894
    A breast cancer sample4--see VAR_0365892 E K mis40--------
    rs1474149101,2
    --67872926(+) AGGCCC/TAAGGT 2 -- us2k10--------
    rs78843921,2
    A,H--67873036(+) CAGAAT/CTGAAA 2 -- us2k1 tfbs34Minor allele frequency- C:0.00NS EA 418
    rs1391444331,2
    --67873082(+) GCTGCA/GCACTA 2 -- us2k10--------
    rs1495434171,2
    --67873147(+) TGGAAC/TGGAAA 2 -- us2k10--------
    rs1872642881,2
    --67873250(+) CCTCAC/GGTCTC 2 -- us2k10--------
    rs78846781,2
    A--67873252(+) TCAGGC/TCTCTG 2 -- us2k10--------
    rs1441606211,2
    C--67873318(+) TCCTCA/GTGTTA 2 -- us2k10--------
    rs1901739011,2
    --67873343(+) GCAGAA/GGGCTT 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for STARD8 (67867508 - 67945684 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for STARD8:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2669195CNV Deletion23128226
    nsv6943CNV Insertion18451855
    nsv6944CNV Loss18451855
    nsv516469CNV Gain19592680
    esv1584074OTHER Inversion17803354


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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 300689    OMIM disorders: --

    2 diseases for STARD8:    About MalaCards
    craniofrontonasal syndrome    

    1 disease from the University of Copenhagen DISEASES database for STARD8:
    Craniofrontonasal syndrome

    STARD8 for disorders           About GeneDecksing

    Genetic Association Database (GAD): STARD8
    Human Genome Epidemiology (HuGE) Navigator: STARD8 (3 documents)

    Export disorders for STARD8 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for STARD8 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with STARD8)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 8724849)1, 2, 3 Nagase T.... Nomura N. (1996)
    2. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    3. Oncogenic inhibition by a deleted in liver cancer gene requires cooperation between tensin binding and Rho-specific GTPase-activating protein activities. (PubMed id 17517630)1, 2 Qian X....Lowy D.R. (2007)
    4. START-GAP3/DLC3 is a GAP for RhoA and Cdc42 and is localized in focal adhesions regulating cell morphology. (PubMed id 17976533)1, 2 Kawai K.... Yagisawa H. (2007)
    5. Deleted in liver cancer 3 (DLC-3), a novel Rho GTPase-activating protein, is downregulated in cancer and inhibits tumor cell growth. (PubMed id 17297465)1, 2 Durkin M.E.... Popescu N.C. (2007)
    6. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
    9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    10. The origin of EFNB1 mutations in craniofrontonasal syndrome: frequent somatic mosaicism and explanation of the paucity of carrier males. (PubMed id 16685650)1 Twigg S.R....Wilkie A.O. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9754 HGNC: 19161 AceView: STARD8 Ensembl:ENSG00000130052 euGenes: HUgn9754
    ECgene: STARD8 H-InvDB: STARD8

    (According to HUGE)
    About This Section
    HUGE: KIAA0189

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for STARD8 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for STARD8 gene:
    Search GeneIP for patents involving STARD8

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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