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Aliases for STARD7 Gene

Aliases for STARD7 Gene

  • StAR-Related Lipid Transfer (START) Domain Containing 7 2 3
  • Gestational Trophoblastic Tumor Protein 1 3 4
  • START Domain-Containing Protein 7 3 4
  • START Domain Containing 7 2 3
  • GTT1 3 4
  • StAR-Related Lipid Transfer Protein 7, Mitochondrial 3
  • StARD7 4

External Ids for STARD7 Gene

Previous GeneCards Identifiers for STARD7 Gene

  • GC02M094722
  • GC02M095304
  • GC02M096318
  • GC02M096335
  • GC02M096272
  • GC02M096850
  • GC02M090811

Summaries for STARD7 Gene

Entrez Gene Summary for STARD7 Gene

  • Although the function of this gene is not known, its existence is supported by mRNA and EST data. The predicted gene product contains a region similar to the STAR-related lipid transfer (START) domain, which is often present in proteins involved in the cell signaling mediated by lipid binding. Alternatively spliced transcript variants have been described, although some transcripts occur only in cancer cell lines. [provided by RefSeq, Jul 2008]

GeneCards Summary for STARD7 Gene

STARD7 (StAR-Related Lipid Transfer (START) Domain Containing 7) is a Protein Coding gene. Diseases associated with STARD7 include gestational trophoblastic tumor and gestational trophoblastic neoplasm. An important paralog of this gene is PCTP.

Gene Wiki entry for STARD7 Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for STARD7 Gene

Genomics for STARD7 Gene

Regulatory Elements for STARD7 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for STARD7 Gene

96,184,859 bp from pter
96,208,835 bp from pter
23,977 bases
Minus strand

Genomic View for STARD7 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for STARD7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for STARD7 Gene

Proteins for STARD7 Gene

  • Protein details for STARD7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    StAR-related lipid transfer protein 7, mitochondrial
    Protein Accession:
    Secondary Accessions:
    • D3DXG9
    • Q53T44
    • Q6GU43
    • Q969M6

    Protein attributes for STARD7 Gene

    370 amino acids
    Molecular mass:
    43113 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAF81750.1; Type=Frameshift; Positions=53; Evidence={ECO:0000305}; Sequence=AAH07894.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH08894.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH09998.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH12774.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH12793.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH13279.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH14076.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH14274.3; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH32106.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for STARD7 Gene

Proteomics data for STARD7 Gene at MOPED

Post-translational modifications for STARD7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for STARD7 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for STARD7 Gene

Domains for STARD7 Gene

Protein Domains for STARD7 Gene

Suggested Antigen Peptide Sequences for STARD7 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 START domain.
  • Contains 1 START domain.
genes like me logo Genes that share domains with STARD7: view

Function for STARD7 Gene

Gene Ontology (GO) - Molecular Function for STARD7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008289 lipid binding IEA --
genes like me logo Genes that share ontologies with STARD7: view

Phenotypes for STARD7 Gene

genes like me logo Genes that share phenotypes with STARD7: view

Animal Model Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for STARD7

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for STARD7 Gene

Localization for STARD7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for STARD7 Gene


Subcellular locations from

Jensen Localization Image for STARD7 Gene COMPARTMENTS Subcellular localization image for STARD7 gene
Compartment Confidence
mitochondrion 3
peroxisome 1

Gene Ontology (GO) - Cellular Components for STARD7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion IEA --
genes like me logo Genes that share ontologies with STARD7: view

Pathways for STARD7 Gene

SuperPathways for STARD7 Gene

No Data Available

Interacting Proteins for STARD7 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000338030 Q9NQZ5-STAR7_HUMAN for STARD7 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for STARD7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903955 positive regulation of protein targeting to mitochondrion IMP 24270810
genes like me logo Genes that share ontologies with STARD7: view

No data available for Pathways by source for STARD7 Gene

Transcripts for STARD7 Gene

Unigene Clusters for STARD7 Gene

StAR-related lipid transfer (START) domain containing 7:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for STARD7

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for STARD7 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c
SP1: - -
SP2: - -
SP3: -

Relevant External Links for STARD7 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for STARD7 Gene

mRNA expression in normal human tissues for STARD7 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for STARD7 Gene

This gene is overexpressed in Neutrophil (29.3), Breast (10.8), and Tlymphocyte (7.6).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for STARD7 Gene

SOURCE GeneReport for Unigene cluster for STARD7 Gene Hs.469331

genes like me logo Genes that share expressions with STARD7: view

Expression partners for STARD7 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for STARD7 Gene

Orthologs for STARD7 Gene

This gene was present in the common ancestor of animals.

Orthologs for STARD7 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia STARD7 35
  • 88.85 (n)
  • 91.82 (a)
  • 92 (a)
(Canis familiaris)
Mammalia STARD7 35
  • 92.58 (n)
  • 95.66 (a)
  • 92 (a)
(Mus musculus)
Mammalia Stard7 35
  • 89.1 (n)
  • 92.16 (a)
Stard7 16
Stard7 36
  • 91 (a)
(Pan troglodytes)
Mammalia STARD7 35
  • 99.46 (n)
  • 99.73 (a)
  • 100 (a)
(Rattus norvegicus)
Mammalia Stard7 35
  • 89.72 (n)
  • 96.28 (a)
(Monodelphis domestica)
Mammalia STARD7 36
  • 68 (a)
(Ornithorhynchus anatinus)
Mammalia STARD7 36
  • 84 (a)
(Anolis carolinensis)
Reptilia STARD7 36
  • 62 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia stard7 35
  • 67.01 (n)
  • 71.18 (a)
(Danio rerio)
Actinopterygii si:dkey-200l5.5 35
  • 64.58 (n)
  • 65 (a)
  • 51 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG6565 37
  • 37 (a)
CG6565 35
  • 45.59 (n)
  • 34.27 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004792 35
  • 45.97 (n)
  • 36.93 (a)
(Caenorhabditis elegans)
Secernentea C06H2.2 36
  • 26 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.7984 36
  • 30 (a)
Species with no ortholog for STARD7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for STARD7 Gene

Gene Tree for STARD7 (if available)
Gene Tree for STARD7 (if available)

Paralogs for STARD7 Gene

Paralogs for STARD7 Gene

genes like me logo Genes that share paralogs with STARD7: view

Variants for STARD7 Gene

Sequence variations from dbSNP and Humsavar for STARD7 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs4826 -- 96,185,147(-) AGGGA(A/G)GAGTC utr-variant-3-prime
rs997547 -- 96,193,296(-) GTGAT(C/T)GAGAG synonymous-codon, reference
rs997548 -- 96,193,176(-) CCTGC(C/T)CCTCC intron-variant
rs1020052 -- 96,186,333(+) CTTTC(C/G)AGGTG utr-variant-3-prime
rs1043708 -- 96,185,080(-) CATAA(A/G)AGAGA utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for STARD7 Gene

Variant ID Type Subtype PubMed ID
dgv650e201 CNV Deletion 23290073
esv5003 CNV Complex 18987735
nsv874677 CNV Loss 21882294
nsv834305 CNV Gain 17160897
nsv525780 CNV Loss 19592680
nsv874679 CNV Gain 21882294

Relevant External Links for STARD7 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for STARD7 Gene

Disorders for STARD7 Gene

(2) University of Copenhagen DISEASES for STARD7 Gene

genes like me logo Genes that share disorders with STARD7: view

No data available for OMIM , UniProtKB/Swiss-Prot , Novoseek inferred disease relationships , Genatlas and External Links for STARD7 Gene

Publications for STARD7 Gene

  1. GTT1/StarD7, a novel phosphatidylcholine transfer protein-like highly expressed in gestational trophoblastic tumour: cloning and characterization. (PMID: 15013637) Durand S. … Genti-Raimondi S. (Placenta 2004) 3 4 23
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns. (PMID: 17672918) Szafranski K. … Platzer M. (Genome Biol. 2007) 3
  4. Activation of beta-catenin signalling increases StarD7 gene expression in JEG-3 cells. (PMID: 19679347) Rena V. … Genti-Raimondi S. (Placenta 2009) 3
  5. StarD7 mediates the intracellular trafficking of phosphatidylcholine to mitochondria. (PMID: 20042613) Horibata Y. … Sugimoto H. (J. Biol. Chem. 2010) 3

Products for STARD7 Gene

Sources for STARD7 Gene

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