Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



STARD5 Gene

protein-coding   GIFtS: 54
GCID: GC15M081601

StAR-Related Lipid Transfer (START) Domain Containing 5

(Previous name: START domain containing 5)
  Search for STARD5
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
StAR-Related Lipid Transfer (START) Domain Containing 51 2
START Domain Containing 51 2
START Domain-Containing Protein 52 3
StAR-Related Lipid Transfer Protein 52
StARD53

External Ids:    HGNC: 180651   Entrez Gene: 807652   Ensembl: ENSG000001723457   OMIM: 6070505   UniProtKB: Q9NSY23   

Export aliases for STARD5 gene to outside databases

Previous GC identifers: GC15M077563 GC15M074762 GC15M079180 GC15M079320 GC15M079392 GC15M058363


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for STARD5 Gene:
Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g.,
SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive
and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol
biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as
steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing
a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD5 (Soccio et al., 2002
(PubMed 12011452)).(supplied by OMIM, Mar 2008)

GeneCards Summary for STARD5 Gene:
STARD5 (StAR-related lipid transfer (START) domain containing 5) is a protein-coding gene. GO annotations related to this gene include lipid binding. An important paralog of this gene is STARD4.

UniProtKB/Swiss-Prot: STAR5_HUMAN, Q9NSY2
Function: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other
sterols (By similarity)

Gene Wiki entry for STARD5 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000015.9  NT_010194.18  NC_018926.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the STARD5 gene promoter:
         STAT5B   GR   HSF1 (long)   N-Myc   HFH-1   FOXO4   c-Myb   HSF1short   GR-alpha   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSTARD5 promoter sequence
   Search Chromatin IP Primers for STARD5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat STARD5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q26   Ensembl cytogenetic band:  15q25.1   HGNC cytogenetic band: 15q26

STARD5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
STARD5 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M081601:  view genomic region     (about GC identifiers)

Start:
81,601,394 bp from pter      End:
81,616,524 bp from pter
Size:
15,131 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: STAR5_HUMAN, Q9NSY2 (See protein sequence)
Recommended Name: StAR-related lipid transfer protein 5  
Size: 213 amino acids; 23794 Da
1 PDB 3D structure from and Proteopedia for STARD5:
2R55 (3D)    
Secondary accessions: P59094
Alternative splicing: 2 isoforms:  Q9NSY2-1   Q9NSY2-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for STARD5: NX_Q9NSY2

Explore proteomics data for STARD5 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See STARD5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_871629.1  
    ENSEMBL proteins: 
     ENSP00000304032   ENSP00000317519   ENSP00000453368  
    Reactome Protein details: Q9NSY2

    STARD5 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for STARD5
    OriGene Protein Over-expression Lysate for STARD5
    OriGene MassSpec for STARD5
    OriGene Custom Protein Services for STARD5
    GenScript Custom Purified and Recombinant Proteins Services for STARD5
    Novus Biologicals STARD5 Proteins
    Novus Biologicals STARD5 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for STARD5

     
    Search eBioscience for Proteins for STARD5 

    STARD5 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for STARD5
    Novus Biologicals STARD5 Antibodies
    Abcam antibodies for STARD5
    Cloud-Clone Corp. Antibodies for STARD5
    Search ThermoFisher Antibodies for STARD5
    LSBio Antibodies in human, mouse, rat for STARD5

    STARD5 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for STARD5
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for STARD5
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for STARD5
    Cloud-Clone Corp. CLIAs for STARD5
    Search eBioscience for ELISAs for STARD5 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    StARD: StAR-related lipid transfer (START) domain containing

    2 InterPro protein domains:
     IPR023393 START-like_dom
     IPR002913 START_lipid-bd_dom

    Graphical View of Domain Structure for InterPro Entry Q9NSY2

    ProtoNet protein and cluster: Q9NSY2

    UniProtKB/Swiss-Prot: STAR5_HUMAN, Q9NSY2
    Similarity: Contains 1 START domain


    Find genes that share domains with STARD5           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: STAR5_HUMAN, Q9NSY2
    Function: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other
    sterols (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008289lipid binding IEA--
         
    Find genes that share ontologies with STARD5           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for STARD5:
     Decreased cilium length after   Decreased influenza A virus in  Upregulation of Wnt/beta-caten 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Stard5):
     skeleton 

    Find genes that share phenotypes with STARD5           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for STARD5
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for STARD5

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for STARD5
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for STARD5

    miRNA
    Products:
        
    miRTarBase miRNAs that target STARD5:
    hsa-mir-26b-5p (MIRT029733), hsa-mir-335-5p (MIRT018134), hsa-mir-30c-5p (MIRT047946)

    Block miRNA regulation of human, mouse, rat STARD5 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate STARD5
    SwitchGear 3'UTR luciferase reporter plasmidSTARD5 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for STARD5
    Predesigned siRNA for gene silencing in human, mouse, rat STARD5

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for STARD5

    Clone
    Products:
         
    OriGene clones in human, mouse for STARD5 (see all 7)
    OriGene ORF clones in mouse, rat for STARD5
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: STARD5 (NM_181900)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for STARD5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat STARD5

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for STARD5
    Browse ESI BIO Cell Lines and PureStem Progenitors for STARD5 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STARD5


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol4
    extracellular2
    endoplasmic reticulum1
    endosome1
    nucleus1
    peroxisome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--

    Find genes that share ontologies with STARD5           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for STARD5 About    
    See pathways by source

    SuperPathContained pathways About
    1Metabolism
    Metabolism0.38
    Metabolism of lipids and lipoproteins0.37
    2Metabolism of steroid hormones and vitamin D
    Pregnenolone biosynthesis0.00
    Metabolism of steroid hormones and vitamin D
    3Cholesterol and Sphingolipids transport Distribution to the intracellular membrane compartments normal and CF
    Cholesterol and Sphingolipids transport Distribution to the intracellular membrane compartments normal and CF


    Find genes that share SuperPaths with STARD5           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for STARD5
        Cholesterol and Sphingolipids transport / Distribution to the intracellular membrane compartments (normal and CF)

    1 Reactome Pathway for STARD5
        Pregnenolone biosynthesis


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for STARD5
    Interactions:

        GeneGlobe Interaction Network for STARD5

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006700C21-steroid hormone biosynthetic process TAS--
    GO:0006869lipid transport IEA--
    GO:0008202steroid metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--

    Find genes that share ontologies with STARD5           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for STARD5 (STAR5)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for STARD5 gene (2 alternative transcripts): 
    NM_030574.2  NM_181900.2  

    Unigene Cluster for STARD5:

    StAR-related lipid transfer (START) domain containing 5
    Hs.513075  [show with all ESTs]
    Unigene Representative Sequence: AK097024
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000302824 ENST00000560916 ENST00000560723(uc002bgm.3) ENST00000325346(uc002bgn.3)
    ENST00000560156 ENST00000559913
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat STARD5 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate STARD5
    SwitchGear 3'UTR luciferase reporter plasmidSTARD5 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for STARD5
    Predesigned siRNA for gene silencing in human, mouse, rat STARD5
    Clone
    Products:
         
    OriGene clones in human, mouse for STARD5 (see all 7)
    OriGene ORF clones in mouse, rat for STARD5
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: STARD5 (NM_181900)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for STARD5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat STARD5
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for STARD5
    OriGene qSTAR qPCR primer pairs in human, mouse for STARD5
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat STARD5
      QuantiTect SYBR Green Assays in human, mouse, rat STARD5
      QuantiFast Probe-based Assays in human, mouse, rat STARD5

    Additional mRNA sequence: 

    AF480304.1 AK026352.1 AK097024.1 AK225479.1 BC004365.1 

    5 DOTS entries:

    DT.100026835  DT.442856  DT.315277  DT.100882542  DT.75132688 

    Selected AceView cDNA sequences (see all 54):

    AF480304 AL137657 BQ672042 H00306 BQ670477 NM_030574 AI380196 BU838609 
    AA888089 BM772811 NM_181900 CF136461 BC004365 CA312327 BU630161 C05110 
    AK026352 N33777 AL709542 BM771732 BU607469 BG681559 AK097024 AI143439 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for STARD5 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b · 6c · 6d
    SP1:                    -           -                                                         
    SP2:                    -     -     -                                                         
    SP3:                    -     -     -                                                         
    SP4:                                -                                                         
    SP5:                                                                                          


    ECgene alternative splicing isoforms for STARD5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    STARD5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TACCGCTCCC
    STARD5 Expression
    About this image


    STARD5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Brain (Nervous System)    fully expand to see all 17 entries
             Thalamus
             Septum   
    STARD5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    STARD5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.513075
        Custom PCR Arrays for STARD5
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for STARD5
    OriGene qSTAR qPCR primer pairs in human, mouse for STARD5
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat STARD5
    QuantiTect SYBR Green Assays in human, mouse, rat STARD5
    QuantiFast Probe-based Assays in human, mouse, rat STARD5
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STARD5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for STARD5 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Stard51 , 5 StAR-related lipid transfer (START) domain containing more1, 5 83.96(n)1
    83.96(a)1
      7 (47.43 cM)5
    1704601  NM_023377.41  NP_075866.21 
     836319595 
    chicken
    (Gallus gallus)
    Aves STARD51 StAR-related lipid transfer (START) domain containing more 66.18(n)
    60.68(a)
      770108  XM_001232611.3  XP_001232612.1 
    lizard
    (Anolis carolinensis)
    Reptilia STARD56
    StAR-related lipid transfer (START) domain contain...
    54(a)
    1 ↔ 1
    GL343894.1(61621-70956)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia stard51 StAR-related lipid transfer (START) domain containing more 64.24(n)
    63.11(a)
      100490468  XM_002932248.2  XP_002932294.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC7968441 stAR-related lipid transfer protein 5-like 59.75(n)
    63.52(a)
      796844  XM_001337204.4  XP_001337240.3 


    ENSEMBL Gene Tree for STARD5 (if available)
    TreeFam Gene Tree for STARD5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for STARD5 gene
    STARD42  STARD62  
    2 SIMAP similar genes for STARD5 using alignment to 2 protein entries:     STAR5_HUMAN (see all proteins):
    STARD4    STARD6

    Find genes that share paralogs with STARD5           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for STARD5
    PGOHUM00000247200


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for STARD5 (see all 307)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs616591951,2
    C,F--81605612(+) AATTGC/TTTCAC 2 K syn12Minor allele frequency- T:0.01WA NA 4670
    rs1926263421,2
    C--81605643(+) AAAACC/TGGGTC 2 Q R mis10--------
    rs1835820441,2
    C--81605655(+) TGCTGC/TGGGGG 2 H R mis10--------
    rs1381880911,2
    C,F--81605656(+) GCTGCG/AGGGGA 2 /R /C mis11Minor allele frequency- A:0.00NA 4552
    rs1495931841,2
    C--81605662(+) GGGGAA/GGAAGG 2 L F mis11Minor allele frequency- G:0.00NA 4552
    rs1435372931,2
    C,F--81605710(+) GGTATG/AGAAGA 2 /H /Y mis12Minor allele frequency- A:0.00NA EU 5875
    rs1491749551,2
    C--81605795(+) GCTGGA/GGACGA 1 -- int10--------
    rs1432803411,2
    --81605936(+) CCTGTC/TGGGGA 1 -- int10--------
    rs1120894651,2
    C--81605951(+) TTCCAT/CAGCCT 1 -- int12Minor allele frequency- C:0.33CSA 3
    rs178755741,2
    C,F--81605990(+) CTACTC/GCCAGC 1 -- int14Minor allele frequency- G:0.04NS WA 208

    HapMap Linkage Disequilibrium report for STARD5 (81601394 - 81616524 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for STARD5:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2749949CNV Deletion23290073

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing STARD5
    DNA2.0 Custom Variant and Variant Library Synthesis for STARD5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 607050    OMIM disorders: --


    Find genes that share disorders with STARD5           About GenesLikeMe

    Genetic Association Database (GAD): STARD5
    Human Genome Epidemiology (HuGE) Navigator: STARD5 (4 documents)

    Export disorders for STARD5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for STARD5 gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with STARD5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The cholesterol-regulated StarD4 gene encodes a StAR-related lipid transfer protein with two closely related homologues, StarD5 and StarD6. (PubMed id 12011452)1, 2, 3 Soccio R.E....Breslow J.L. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    2. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Differential gene regulation of StarD4 and StarD5 cholesterol transfer proteins. Activation of StarD4 by sterol regulatory element-binding protein-2 and StarD5 by endoplasmic reticulum stress. (PubMed id 15760897)1, 9 Soccio R.E....Breslow J.L. (J. Biol. Chem. 2005)
    6. Human StarD5, a cytosolic StAR-related lipid binding protein. (PubMed id 15897605)1, 9 Rodriguez-Agudo D....Pandak W.M. (J. Lipid Res. 2005)
    7. Comparative structural analysis of lipid binding START domains. (PubMed id 21738568)2 Thorsell A.G.... Lehtio L. (PLoS ONE 2011)
    8. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (Genes Immun. 2010)
    9. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (Am. J. Hum. Genet. 2009)
    10. Steroidogenic acute regulatory-related lipid transfer domain protein 5 localization and regulation in renal tubules. (PubMed id 19474188)1 Chen Y.C....Clark B.J. (Am. J. Physiol. Renal Physiol. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 80765 HGNC: 18065 AceView: STARD5 Ensembl:ENSG00000172345 euGenes: HUgn80765
    ECgene: STARD5 H-InvDB: STARD5

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for STARD5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for STARD5 gene:
    Search GeneIP for patents involving STARD5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for STARD5  
     OriGene qPCR primer pairs and template standards for STARD5   OriGene Protein Over-expression Lysate for STARD5  
     OriGene MassSpec something-or-other for STARD5   OriGene clones in human, mouse for STARD5  
     OriGene qSTAR qPCR primer pairs in human, mouse for STARD5   OriGene Purified Protein for STARD5  
     OriGene ORF clones in mouse, rat for STARD5   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for STARD5   OriGene Custom Protein Services for STARD5  

     
     
     Block miRNA regulation of human, mouse, rat STARD5 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing STARD5
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat STARD5 Predesigned siRNA for gene silencing in human, mouse, rat STARD5
     QuantiFast Probe-based Assays in human, mouse, rat STARD5 QuantiTect SYBR Green Assays in human, mouse, rat STARD5
     Custom PCR Arrays for STARD5 Search Chromatin IP Primers for STARD5
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat STARD5  GeneGlobe Interaction Network for STARD5
     Regulatory tfbs in STARD5 promoter
     GenScript Custom Purified and Recombinant Proteins Services for STARD5 GenScript cDNA clones with any tag delivered in your preferred vector for STARD5
     GenScript Custom Assay Services for STARD5 GenScript Custom overexpressing Cell Line Services for STARD5
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for STARD5 (STAR5)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     STARD5 antibodies
     STARD5 proteins
     STARD5 lysates
     Antibodies for STARD5
     See all of Abcam's Antibodies, Kits and Proteins for STARD5
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for STARD5
     Antibodies for STARD5
     ELISAs for STARD5
     CLIAs for STARD5



     Browse ESI BIO Cell Lines and PureStem Progenitors for STARD5
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STARD5
     SwitchGear 3'UTR luciferase reporter plasmids for STARD5
     SwitchGear Promoter luciferase reporter plasmids for STARD5
     Search ThermoFisher Antibodies for STARD5
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat STARD5
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for STARD5
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for STARD5
     LSBio Antibodies in human, mouse, rat for STARD5
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for STARD5
      Search eBioscience for proteins for STARD5
      Search eBioscience for elisas for STARD5
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      STARD5 gene at Home site.
    Version: 3.12.212 17 Sep 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4