Aliases for STARD3 Gene
External Ids for STARD3 Gene
Previous GeneCards Identifiers for STARD3 Gene
This gene encodes a member of a subfamily of lipid trafficking proteins that are characterized by a C-terminal steroidogenic acute regulatory domain and an N-terminal metastatic lymph node 64 domain. The encoded protein localizes to the membranes of late endosomes and may be involved in exporting cholesterol. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]
GeneCards Summary for STARD3 Gene
STARD3 (StAR Related Lipid Transfer Domain Containing 3) is a Protein Coding gene. Among its related pathways are Cholesterol and Sphingolipids transport / Distribution to the intracellular membrane compartments (normal and CF) and Metabolism of steroid hormones. GO annotations related to this gene include lipid binding and cholesterol transporter activity. An important paralog of this gene is STARD3NL.
UniProtKB/Swiss-Prot for STARD3 Gene
Binds and transports cholesterol. Promotes steroidogenesis in placenta and brain.