Aliases for STAP1 Gene
External Ids for STAP1 Gene
The protein encoded by this gene functions as a docking protein acting downstream of Tec tyrosine kinase in B cell antigen receptor signaling. The protein is directly phosphorylated by Tec in vitro where it participates in a postive feedback loop, increasing Tec activity. [provided by RefSeq, Jul 2008]
GeneCards Summary for STAP1 Gene
STAP1 (Signal Transducing Adaptor Family Member 1) is a Protein Coding gene. Among its related pathways are Kit Receptor Signaling Pathway and B Cell Receptor Signaling Pathway (WikiPathways). GO annotations related to this gene include phospholipid binding and SH3/SH2 adaptor activity. An important paralog of this gene is STAP2.
UniProtKB/Swiss-Prot for STAP1 Gene
In BCR signaling, appears to function as a docking protein acting downstream of TEC and participates in a positive feedback loop by increasing the activity of TEC.