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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

STAG3 Gene

protein-coding   GIFtS: 57
GCID: GC07P099775

stromal antigen 3
 Explore 6 diseases affiliated with
STAG3 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for STAG3    

Aliases
for STAG3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Stromal Antigen 31 2 3
SCC3 Homolog 32 3
Cohesin Subunit SA-32
Stromalin 32
Stromalin-33
Stromalin-33

External Ids:    HGNC: 113561   Entrez Gene: 107342   Ensembl: ENSG000000669237   OMIM: 6084895   UniProtKB: Q9UJ983   

Export aliases for STAG3 gene to outside databases

Previous GC identifers: GC07P098310 GC07P099372 GC07P099386 GC07P099419 GC07P099613 GC07P094410


Summaries
for STAG3 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: STAG3_HUMAN, Q9UJ98
Function: Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister
chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister
chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister
chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when
it dissociates from chromatin during prophase I (By similarity)




Genomic Views
for STAG3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.1  NT_007933.15  NT_079595.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the STAG3 gene promoter:
         Max1   E2F-3a   E2F-4   E2F-5   Sp1   E2F-2   AREB6   E2F   E2F-1   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): STAG3 promoter sequence
   Search SABiosciences Chromatin IP Primers for STAG3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat STAG3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q22.1   Ensembl cytogenetic band:  7q22.1   HGNC cytogenetic band: 7q22

STAG3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
STAG3 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P099775:  view genomic region     (about GC identifiers)

Start:
 99,775,186 bp from pter      End:
 99,819,111 bp from pter
Size:
 43,926 bases      Orientation:
 plus strand

1 alternative location:
Chr7+,CRA_TCAG 99,135,619-99,172,096     

Proteins
for STAG3 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: STAG3_HUMAN, Q9UJ98 (See protein sequence)
Recommended Name: Cohesin subunit SA-3  
Size: 1225 amino acids; 139034 Da
Subunit: Component of the meiosis-specific cohesin complex, which also contains the SMC1 (SMC1A or SMC1B) and SMC3
heterodimer. Such complex likely contains RAD21, or the meiosis-specific related protein REC8 (By similarity)
Subcellular location: Nucleus. Chromosome. Chromosome, centromere. Note=Associates with chromatin. In prophase I stage
of meiosis, it is found along the axial elements of synaptonemal complexes. In late-pachytene-diplotene, the bulk of
protein dissociates from the chromosome arms probably because of phosphorylation by PLK1, except at centromeres, where
cohesin complexes remain. It however remains chromatin associated at the centromeres up to metaphase I. During
anaphase I, it probably dissociates from centromeres, allowing chromosomes segregation
Secondary accessions: A6H8Z1 D6W5U8 Q8NDP3
Alternative splicing: 2 isoforms:  Q9UJ98-1   Q9UJ98-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for STAG3: NX_Q9UJ98

Post-translational modifications:

  • Phosphorylated (By similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9UJ98

    • STAG3 Protein expression data from MOPED and PaxDb:    About this image 
    STAG3 Protein Expression
    REFSEQ proteins: NP_036579.2  
    ENSEMBL proteins: 
     ENSP00000400359   ENSP00000377586   ENSP00000409283   ENSP00000319318   ENSP00000407884  
     ENSP00000397067   ENSP00000395039   ENSP00000393790  
    Reactome Protein details: Q9UJ98
    Human Recombinant Protein Products for STAG3: 
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for STAG3

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000775chromosome, centromeric region IEA--
    GO:0000795synaptonemal complex TAS10698974
    GO:0000802transverse filament IEA--
    GO:0001673male germ cell nucleus IEA--
    GO:0005634nucleus TAS10698974

    STAG3 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for STAG3

    Protein Domains /
    Families
    for STAG3 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    STAG3 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR020839 SCD
     IPR013721 STAG
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry Q9UJ98

    ProtoNet protein and cluster: Q9UJ98

    1 Blocks protein family: IPB013721 STAG

    UniProtKB/Swiss-Prot: STAG3_HUMAN, Q9UJ98
    Similarity: Belongs to the SCC3 family
    Similarity: Contains 1 SCD (stromalin conservative) domain


    Function
    for STAG3 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Molecular Function:

         UniProtKB/Swiss-Prot Summary: STAG3_HUMAN, Q9UJ98
    Function: Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister
    chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister
    chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister
    chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when
    it dissociates from chromatin during prophase I (By similarity)

    Phenotypes:
         1 GenomeRNAi human phenotype for STAG3:

     Increased cell transformation 

         1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Stag3):
     reproductive system 

    STAG3 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for STAG3 

    miRNA
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    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STAG3


    Pathways & Interactions
    for STAG3 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Meiotic Synapsis
    		Meiotic Synapsis1.00
    		Meiosis0.70
    		Telomere clustering at the nuclear membrane0.82
    		Chromosome Maintenance0.56
    2Synapsis
    		Synapsis1.00
    		Formation of Axial/Lateral Elements of Synaptonemal Complex0.56
    3Meiosis
    		Meiosis1.00
    4Oocyte meiosis
    		Oocyte meiosis1.00
    5Cell Cycle
    		Cell Cycle1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for STAG3
        Meiosis


    5/7        Reactome Pathways for STAG3 (see all 7)
        Synapsis
    Meiotic Synapsis
    Cell Cycle
    Meiosis
    Chromosome Maintenance


    1         Kegg Pathway  (Kegg details for STAG3):
        Oocyte meiosis


    STAG3 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for STAG3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    5/10 Interacting proteins for STAG3 (Q9UJ983 ENSP000003193184) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMC1AQ146833, ENSP000003234214I2D: score=1 STRING: ENSP00000323421
    SMC3Q9UQE73, ENSP000003547204I2D: score=1 STRING: ENSP00000354720
    SGOL1ENSP000002637534STRING: ENSP00000263753
    SGOL2ENSP000003504474STRING: ENSP00000350447
    SMC1BENSP000003500364STRING: ENSP00000350036
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007059chromosome segregation IEA--
    GO:0007130synaptonemal complex assembly TAS10698974

    STAG3 for ontologies           About GeneDecksing



    Drugs & Compounds
    for STAG3 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for STAG3
    Search CenterWatch for drugs/clinical trials and news about STAG3 

    Transcripts
    for STAG3 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for STAG3 gene: 
    NM_012447.2  

    Unigene Cluster for STAG3:

    Stromal antigen 3
    Hs.592283  [show with all ESTs]
    Unigene Representative Sequence: AJ007798
    18/21 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21):
    ENST00000426455 ENST00000394018 ENST00000416412 ENST00000317296(uc003utx.1 uc011kjk.1)
    ENST00000422690 ENST00000496157(uc010lgs.1) ENST00000439782 ENST00000482546
    ENST00000459699 ENST00000489373 ENST00000498547 ENST00000483309 ENST00000480871
    ENST00000491498 ENST00000440830(uc003uub.1) ENST00000477469 ENST00000476057
    ENST00000479359

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat STAG3
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    SwitchGear 3'UTR luciferase reporter plasmid: STAG3 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for STAG3 (see all 7)
    OriGene shRNA RFP: STAG3
    OriGene siRNA: STAG3
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    Sirion Biotech Custom design and validation of potent shRNA sequences against STAG3 
    Clone
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    Primer
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    Additional cDNA sequence: 

    AJ007798.2 AK056272.1 AK292394.1 AK302587.1 AK302693.1 BC028684.1 BC047490.1 BC140932.1 
    BC146806.1 

    20 DOTS entries:

    DT.95230593  DT.92469847  DT.121100082  DT.100774188  DT.75146127  DT.40238600  DT.432669  DT.95333365 
    DT.121099895  DT.92324296  DT.100776899  DT.121099824  DT.100675971  DT.121099926  DT.121099951  DT.40255185 
    DT.95109896  DT.121099893  DT.40118640  DT.426930 

    24/151 AceView cDNA sequences (see all 151):

    AI492067 AL833816 BC073861 CR596791 CR622860 AA077439 BM921510 BE045461 
    CR612233 BC047490 CR597586 BQ424845 AL044674 AL042720 AW732742 AL048960 
    BI834841 AI568276 BC001129 BG340546 AA077510 AJ007798 BE513801 BE514226 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for STAG3    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14
    SP1:                          -                                                                                                               
    SP2:                                                                                                                                          
    SP3:                    -     -                                   -     -                                                                     
    SP4:                                                  -     -     -     -     -     -     -     -     -     -     -     -     -               
    SP5:        -     -     -     -                                                                                                               


    ECgene alternative splicing isoforms for STAG3

    Expression
    for STAG3 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    STAG3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTTGAATCCA
    STAG3 Expression
    About this image

    STAG3 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    TestisSeminiferous TubulesPrimary SpermatocyteGerm Cells, Male Gametocytes
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Sox17-GFP genetically modified stem cells (Embryonic Stem Cell)Early Embryo, Inner Cell Mass

    See STAG3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for STAG3

    SOURCE GeneReport for Unigene cluster: Hs.592283

    UniProtKB/Swiss-Prot: STAG3_HUMAN, Q9UJ98
    Tissue specificity: Testis specific

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    In Situ
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    Orthologs
    for STAG3 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for STAG3 gene from 6/21 species (see all 21)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    lizard
    (Anolis carolinensis)    		 Reptilia --
    		 --
    		 55(a)
    		 1 → many
    		 GL343882.1(39323-62152)
    zebrafish
    (Danio rerio)    		 Actinopterygii si:ch211-269e2.16
    		 si:ch211-269e2.1
    		 36(a)
    		 1 → many
    		 9(35404357-35454541)
    fruit fly
    (Drosophila melanogaster)    		 Insecta SA3   -- 42(a)   27C7   --
    worm
    (Caenorhabditis elegans)    		 Secernentea scc-36
    		 yeast SCC (mitotic condensin subunit) homolog fami...
    		 30(a)
    		 1 → many
    		 V(12763928-12767921)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons SCC36
    		 cohesin complex subunit SA-1/2
    		 22(a)
    		 1 → many
    		 2(19631259-19636978)
    rice
    (Oryza sativa)    		 Liliopsida --
    		 SCC3, putative, expressed
    		 21(a)
    		 1 → many
    		 5(5424284-5433068)


    ENSEMBL Gene Tree for STAG3 (if available)
    TreeFam Gene Tree for STAG3 (if available) 

    Paralogs
    for STAG3 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for STAG3 gene
    STAG12  STAG3L32  STAG22  
    12 SIMAP similar genes for STAG3 using alignment to 8 protein entries:     STAG3_HUMAN (see all proteins):
    DKFZp434P091    STAG3L1    STAG3L2    STAG3L3    STAG1    DKFZp686C21148
    DKFZp686P16143    DKFZp686I05169    DKFZp686P168    STAG1 variant protein    STAG2    DKFZp781D1416

    STAG3 for paralogs           About GeneDecksing


    5/6 Pseudogenes.org Pseudogenes for STAG3 (see all 6)
    PGOHUM00000262475 PGOHUM00000232944 PGOHUM00000232946 PGOHUM00000263183 PGOHUM00000262489


    Genomic Variants
    for STAG3 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/647 NCBI SNPs in STAG3 are shown (see all 647)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 7 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1156602681,2
    		C,F--99773560(+) GGCCAA/GAGAAT 1 -- us2k11Minor allele frequency- G:0.09WA 118
    rs69549411,2
    		C--99773565(+) AAGAAC/TGGGGA 1 -- us2k10--------
    rs1161385801,2
    		F--99773676(+) GGGGAG/AGGCAG 1 -- us2k11Minor allele frequency- A:0.06WA 118
    rs746626311,2
    		C,F--99773879(+) GAGCCG/ACTGTC 1 -- us2k13Minor allele frequency- A:0.02WA NA EU 5897
    rs1461712631,2
    		C,F--99773974(+) ACAGAC/TCCGGA 1 -- us2k11Minor allele frequency- T:0.00NA 4552
    rs2020859891,2
    		--99774004(+) GAGACG/TTGAAG 1 -- us2k10--------
    rs1439606991,2
    		C--99774030(+) ATATCC/GTAAAA 1 -- us2k10--------
    rs125344791,2
    		C,H--99774092(+) CCTGGG/TCTCTT 1 -- us2k1 trp30--------
    rs1481964121,2
    		C--99774096(+) GTCTC-/TTTTCTA 1 -- us2k10--------
    rs127050731,2
    		C,F,A,H--99774122(+) TTCCCC/TACCTG 1 -- us2k1 trp323Minor allele frequency- T:0.49NS EA NA WA CSA 2350

    HapMap Linkage Disequilibrium report for STAG3 (99775186 - 99819111 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for STAG3
         1 CNV: 64901

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    Disorders / Diseases
    for STAG3 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    STAG3 for disorders           About GeneDecksing

    OMIM gene information: 608489    OMIM disorders: --

    6 diseases for STAG3:    About MalaCards
    williams-beuren syndrome    male infertility    epithelial ovarian cancer    ovarian cancer
    infertility    colorectal cancer

    1 disease from the University of Copenhagen DISEASES database for STAG3:
    Male infertility
    Human Genome Epidemiology (HuGE) Navigator: STAG3 (2 documents)

    Export disorders for STAG3 gene to outside databases

    Publications
    for STAG3 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for STAG3 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with STAG3)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. STAG3, a novel gene encoding a protein involved in meiotic chromosome pairing and location of STAG3-related genes flanking the Williams- Beuren syndrome deletion. (PubMed id 10698974)1, 2, 3, 9 Pezzi N.... Barbero J.L. (2000)
    2. STAG2 and Rad21 mammalian mitotic cohesins are implicated in meiosis. (PubMed id 12034751)1, 2 Prieto I.... Barbero J.L. (2002)
    3. Common alleles in candidate susceptibility genes asso ciated with risk and development of epithelial ovarian cancer. (PubMed id 20635389)1 Notaridou M.... . (2010)
    4. Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival. (PubMed id 19270026)1 Quaye L....Gayther S.A. (2009)
    5. Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers. (PubMed id 18299561)1 Barber T.D....Hieter P. (2008)
    6. [Function of cohesin in transcription] (PubMed id 18788457)1 Maeshima K....Shirahige K. (2008)
    7. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Mammalian STAG3 is a cohesin specific to sister chrom atid arms in meiosis I. (PubMed id 11483963)1 Prieto I....Barbero J.L. (2001)

    External Searches for STAG3 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
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    Genome Databases showing STAG3 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10734 HGNC: 11356 AceView: STAG3 Ensembl:ENSG00000066923 euGenes: HUgn10734
    ECgene: STAG3 Kegg: 10734 H-InvDB: STAG3

    Other Databases showing STAG3 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing STAG3 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for STAG3 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for STAG3 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for STAG3 gene:
    Search GeneIP for patents involving STAG3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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