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STAC3 Gene

protein-coding   GIFtS: 47
GCID: GC12M057637

SH3 And Cysteine Rich Domain 3

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
SH3 And Cysteine Rich Domain 31 2
NAM2 5
SH3 And Cysteine-Rich Domain-Containing Protein 32

External Ids:    HGNC: 284231   Entrez Gene: 2463292   Ensembl: ENSG000001854827   OMIM: 6155215   UniProtKB: Q96MF23   

Export aliases for STAC3 gene to outside databases

Previous GC identifers: GC12M055924 GC12M055925 GC12M054676


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for STAC3 Gene:
The protein encoded by this gene is a component of the excitation-contraction coupling machinery of muscles. This
protein is a member of the Stac gene family and contains an N-terminal cysteine-rich domain and two SH3 domains.
Mutations in this gene are a cause of Native American myopathy. (provided by RefSeq, Nov 2013)

GeneCards Summary for STAC3 Gene:
STAC3 (SH3 and cysteine rich domain 3) is a protein-coding gene. Diseases associated with STAC3 include native american myopathy. GO annotations related to this gene include identical protein binding. An important paralog of this gene is STAC.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000012.12  NC_018923.2  NT_029419.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the STAC3 gene promoter:
         Nkx3-1   Elk-1   Nkx3-1 v4   Spz1   HOXA3   Nkx3-1 v1   Evi-1   Nkx3-1 v2   HOXA5   Nkx3-1 v3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSTAC3 promoter sequence
   Search Chromatin IP Primers for STAC3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat STAC3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.3   Ensembl cytogenetic band:  12q13.3   HGNC cytogenetic band: 12q13.2

STAC3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
STAC3 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M057637:  view genomic region     (about GC identifiers)

Start:
57,637,236 bp from pter      End:
57,644,976 bp from pter
Size:
7,741 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: STAC3_HUMAN, Q96MF2 (See protein sequence)
Recommended Name: SH3 and cysteine-rich domain-containing protein 3  
Size: 364 amino acids; 41507 Da
1 PDB 3D structure from and Proteopedia for STAC3:
2DB6 (3D)    
Secondary accessions: Q96HU5
Alternative splicing: 2 isoforms:  Q96MF2-1   Q96MF2-2   

Explore the universe of human proteins at neXtProt for STAC3: NX_Q96MF2

Explore proteomics data for STAC3 at MOPED


See STAC3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (3 alternative transcripts): 
NP_001273185.1  NP_001273186.1  NP_659501.1  

ENSEMBL proteins: 
 ENSP00000452068   ENSP00000329200   ENSP00000450740   ENSP00000441515   ENSP00000452299  

STAC3 Human Recombinant Protein Products:

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Novus Biologicals STAC3 Protein
Novus Biologicals STAC3 Lysate
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Browse Sino Biological Cell Lysates
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Cloud-Clone Corp. Proteins for STAC3

STAC3 Antibody Products:

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Novus Biologicals STAC3 Antibodies
Search for Antibodies for STAC3 at Abcam
Cloud-Clone Corp. Antibodies for STAC3
Search ThermoFisher Antibodies for STAC3
LSBio Antibodies in human, mouse, rat for STAC3

STAC3 Assay Products:

Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for STAC3
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for STAC3
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for STAC3
Cloud-Clone Corp. CLIAs for STAC3


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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3 InterPro protein domains:
 IPR011511 SH3_2
 IPR002219 Prot_Kinase_C-like_PE/DAG-bd
 IPR001452 SH3_domain

Graphical View of Domain Structure for InterPro Entry Q96MF2

ProtoNet protein and cluster: Q96MF2

2 Blocks protein domains:
IPB001452 SH3 domain signature
IPB011511 Variant SH3


UniProtKB/Swiss-Prot: STAC3_HUMAN, Q96MF2
Similarity: Contains 1 phorbol-ester/DAG-type zinc finger
Similarity: Contains 2 SH3 domains


STAC3 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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     Gene Ontology (GO): 3 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005515protein binding ----
GO:0042802identical protein binding IPI16189514
GO:0046872metal ion binding IEA--
     
STAC3 for ontologies           About GeneDecksing


Phenotypes:
     2 GenomeRNAi human phenotypes for STAC3:
 Decreased influenza A virus in  Decreased nuclei size in G2M 

     5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Stac3):
 behavior/neurological  cardiovascular system  growth/size/body  mortality/aging  muscle 

STAC3 for phenotypes           About GeneDecksing

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for STAC3
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for STAC3

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for STAC3
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for STAC3

miRNA
Products:
    
Block miRNA regulation of human, mouse, rat STAC3 using miScript Target Protectors
2 qRT-PCR Assays for microRNAs that regulate STAC3:
hsa-miR-612 hsa-miR-1285
SwitchGear 3'UTR luciferase reporter plasmidSTAC3 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for STAC3
Predesigned siRNA for gene silencing in human, mouse, rat STAC3

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for STAC3

Clone
Products:
     
OriGene clones in human, mouse for STAC3 (see all 6)
OriGene ORF clones in mouse, rat for STAC3
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: STAC3 (NM_145064)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for STAC3
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat STAC3

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for STAC3
Browse ESI BIO Cell Lines and PureStem Progenitors for STAC3 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STAC3


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
cytosol3
nucleus2

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for STAC3
Interactions:

    Search GeneGlobe Interaction Network for STAC3

STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

Selected Interacting proteins for STAC3 (Q96MF21, 2, 3 ENSP000003292004) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
InteractantInteraction Details
GeneCardExternal ID(s)
ZCCHC10Q8TBK62, 3, ENSP000003242744MINT-67626 I2D: score=4 STRING: ENSP00000324274
STAC3Q96MF21, 2EBI-745680,EBI-745680 MINT-67612
PPARAQ078693, ENSP000002627354I2D: score=1 STRING: ENSP00000262735
ENKD1Q9H0I23I2D: score=1 
PLAAENSP000003804604STRING: ENSP00000380460
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Gene Ontology (GO): 1 biological process term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0035556intracellular signal transduction IEA--

STAC3 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for STAC3

Selected HMDB Compounds for STAC3 (see all 843)    About this table
CompoundSynonyms CAS #PubMed Ids
DG(14:0/14:0/0:0)DAG(14:0/14:0) (see all 9)----
DG(14:0/14:1(9Z)/0:0)DAG(14:0/14:1) (see all 15)----
DG(14:0/15:0/0:0)Diacylglycerol(29:0) (see all 9)----
DG(14:0/16:0/0:0)DAG(30:0) (see all 9)----
DG(14:0/16:1(9Z)/0:0)DG(30:1) (see all 15)----
DG(14:0/18:0/0:0)DG(14:0/18:0) (see all 9)----
DG(14:0/18:1(11Z)/0:0)Diacylglycerol (see all 15)----
DG(14:0/18:1(9Z)/0:0)1-myristoyl-2-oleoyl-sn-glycerol (see all 15)----
DG(14:0/18:2(9Z,12Z)/0:0)DAG(14:0/18:2n6) (see all 15)----
DG(14:0/18:3(6Z,9Z,12Z)/0:0)Diacylglycerol(14:0/18:3n6) (see all 16)----



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for STAC3 gene (3 alternative transcripts): 
NM_001286256.1  NM_001286257.1  NM_145064.2  

Unigene Cluster for STAC3:

SH3 and cysteine rich domain 3
Hs.417595  [show with all ESTs]
Unigene Representative Sequence: AK057013
7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000554578 ENST00000332782(uc009zpl.2 uc001snp.2 uc001snq.2 uc010srm.1)
ENST00000557176 ENST00000546246 ENST00000554003 ENST00000553489 ENST00000553294

miRNA
Products:
     
Block miRNA regulation of human, mouse, rat STAC3 using miScript Target Protectors
2 qRT-PCR Assays for microRNAs that regulate STAC3:
hsa-miR-612 hsa-miR-1285
SwitchGear 3'UTR luciferase reporter plasmidSTAC3 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for STAC3
Predesigned siRNA for gene silencing in human, mouse, rat STAC3
Clone
Products:
     
OriGene clones in human, mouse for STAC3 (see all 6)
OriGene ORF clones in mouse, rat for STAC3
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: STAC3 (NM_145064)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for STAC3
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat STAC3
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for STAC3
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat STAC3
  QuantiTect SYBR Green Assays in human, mouse, rat STAC3
  QuantiFast Probe-based Assays in human, mouse, rat STAC3

Additional mRNA sequence: 

AK057013.1 AK300688.1 AK311513.1 BC008069.2 

7 DOTS entries:

DT.92420434  DT.40117610  DT.97837688  DT.91710241  DT.100646867  DT.92420432  DT.95272720 

Selected AceView cDNA sequences (see all 62):

NM_145064 BM716925 AW410140 BC008069 AA192831 AW410547 AK057013 F31205 
CD367060 BE294470 BG829317 AW410546 BE296948 BU738507 CD364582 AI457719 
BG827109 AW247926 BE205917 BF309526 AW249168 BM713044 BF304643 BG828884 

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for STAC3    About this scheme

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13
SP1:                                                                                          
SP2:              -     -     -     -     -                                                   
SP3:              -                                                                           
SP4:                                                                                          


ECgene alternative splicing isoforms for STAC3

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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STAC3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: ATGGAGGAGG
STAC3 Expression
About this image

STAC3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

STAC3 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.417595
    Custom PCR Arrays for STAC3
Primer
Products:
OriGene qSTAR qPCR primer pairs in human, mouse for STAC3
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat STAC3
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QuantiFast Probe-based Assays in human, mouse, rat STAC3
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STAC3

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for STAC3 gene from Selected species (see all 10)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Stac31 , 5 SH3 and cysteine rich domain 31, 5 90.34(n)1
93.59(a)1
  10 (74.50 cM)5
2376111  NM_177707.31  NP_808375.11 
 1275016865 
lizard
(Anolis carolinensis)
Reptilia STAC36
SH3 and cysteine rich domain 3
71(a)
1 ↔ 1
GL343212.1(1167023-1202043)
tropical clawed frog
(Xenopus tropicalis)
Amphibia stac31 SH3 and cysteine rich domain 3 73.71(n)
81.07(a)
  493233  NM_001007506.1  NP_001007507.1 
zebrafish
(Danio rerio)
Actinopterygii stac31 SH3 and cysteine rich domain 3 66.98(n)
66.98(a)
  445111  NM_001003505.1  NP_001003505.1 
fruit fly
(Drosophila melanogaster)
Insecta CG437296
--
6(a)
1 → many
2R(11288601-11358596)


ENSEMBL Gene Tree for STAC3 (if available)
TreeFam Gene Tree for STAC3 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for STAC3 gene
STAC2  STAC22  
3 SIMAP similar genes for STAC3 using alignment to 4 protein entries:     STAC3_HUMAN (see all proteins):
STAC    ARHGEF7    STAC2

STAC3 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for STAC3 (see all 251)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 12 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1512021191,2
--57636824(+) GCCCAA/GGGTCT 1 -- ds50010--------
rs1906302311,2
C--57636861(+) CCTTAC/TCCACC 1 -- ds50010--------
rs1831487831,2
C--57636868(+) CACCCG/TCCACC 1 -- ds50010--------
rs1402713821,2
C--57636901(+) AACCGA/GGATCT 1 -- ds50010--------
rs1154469011,2
C,F--57637091(+) AGAGGC/ACTCAC 1 -- ds50011Minor allele frequency- A:0.03WA 118
rs1168113001,2
F--57637127(+) GCCAAC/ACTCAG 1 -- ds50011Minor allele frequency- A:0.05WA 118
rs1453852671,2
C--57637163(+) TGGTAA/CCGAGG 1 -- ds50010--------
rs1874124991,2
--57637525(+) GCCCCC/GCTCCC 1 -- ut310--------
rs3713770481,2
C--57637526(+) CCCCCA/CCCCCA 1 -- ut310--------
rs32046351,2
C,F,H--57637593(-) TTAGGC/TGTGCG 1 -- ut3127Minor allele frequency- T:0.22MN NS EA NA WA CSA EU 7378

HapMap Linkage Disequilibrium report for STAC3 (57637236 - 57644976 bp)

Structural Variations
     Database of Genomic Variants (DGV) 2 variations for STAC3:    About this table    
Variant IDTypeSubtypePubMed ID
dgv96n21CNV Loss19592680
nsv519293CNV Loss19592680

Human Gene Mutation Database (HGMD): STAC3
Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing STAC3
DNA2.0 Custom Variant and Variant Library Synthesis for STAC3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 615521   
OMIM disorders: 255995  
1 disease for STAC3:    
About MalaCards
native american myopathy


STAC3 for disorders           About GeneDecksing


Export disorders for STAC3 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for STAC3 gene integrated from 10 sources:
(articles sorted by number of sources associating them with STAC3)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  4. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (Nat. Methods 2013)
  5. Stac3 is a component of the excitation-contraction coupling machinery and mutated in Native American myopathy. (PubMed id 23736855)1 Horstick E.J....Kuwada J.Y. (Nat Commun 2013)
  6. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
  7. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (Nature 2005)
  8. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (Genome Res. 1996)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 246329 HGNC: 28423 AceView: STAC3 Ensembl:ENSG00000185482 euGenes: HUgn246329
ECgene: STAC3 H-InvDB: STAC3

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for STAC3 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for STAC3 gene:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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