Aliases for ST8SIA2 Gene
External Ids for ST8SIA2 Gene
Previous Symbols for ST8SIA2 Gene
The protein encoded by this gene is a type II membrane protein that is thought to catalyze the transfer of sialic acid from CMP-sialic acid to N-linked oligosaccharides and glycoproteins. The encoded protein may be found in the Golgi apparatus and may be involved in the production of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). This protein is a member of glycosyltransferase family 29. [provided by RefSeq, Jul 2008]
GeneCards Summary for ST8SIA2 Gene
ST8SIA2 (ST8 Alpha-N-Acetyl-Neuraminide Alpha-2,8-Sialyltransferase 2) is a Protein Coding gene. Among its related pathways are L1CAM interactions and L1CAM interactions. GO annotations related to this gene include sialic acid binding and alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity. An important paralog of this gene is ST8SIA1.
UniProtKB/Swiss-Prot for ST8SIA2 Gene
May transfer sialic acid through alpha-2,8-linkages to the alpha-2,3-linked and alpha-2,6-linked sialic acid of N-linked oligosaccharides of glycoproteins and may be involved in PSA (polysialic acid) expression