Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ST7-OT4 Gene

Subcategory (RNA class) for ST7-OT4 Gene

ncRNA

Quality Score for this RNA gene is

3

Aliases for ST7-OT4 Gene

  • ST7 Overlapping Transcript 4 2 3 5
  • ST7 Overlapping Transcript 4 (Non-Protein Coding) 2 3
  • ST7 Overlapping Transcript 4 (Non-Coding RNA) 3
  • Non-Protein Coding RNA 42 2
  • NCRNA00042 3
  • ST7OT4 3

External Ids for ST7-OT4 Gene

Previous HGNC Symbols for ST7-OT4 Gene

  • ST7OT4

Previous GeneCards Identifiers for ST7-OT4 Gene

  • GC07P116596
  • GC07P116598
  • GC07P116958
  • GC07P116963
  • GC07P116967
  • GC07P116971

Summaries for ST7-OT4 Gene

GeneCards Summary for ST7-OT4 Gene

ST7-OT4 (ST7 Overlapping Transcript 4) is an RNA Gene, and is affiliated with the ncRNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ST7-OT4 Gene

Genomics for ST7-OT4 Gene

Regulatory Elements for ST7-OT4 Gene

Enhancers for ST7-OT4 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F116575 1.7 FANTOM5 Ensembl ENCODE 10 -376.4 -376380 3.2 PKNOX1 ARNT CREB3L1 SIN3A FEZF1 ZNF2 YY1 ZNF766 ZNF302 FOS ST7-AS1 ENSG00000228368 LOC100506489 LOC100130680 LOC105375467 LOC102724407 ENSG00000237813 ENSG00000235427 CAV2 ST7-OT4
GH07F116209 1.2 ENCODE 9.9 -739.1 -739139 10.0 CREB3L1 FEZF1 DMAP1 YY1 ZNF143 ZNF548 ZNF263 SP3 NFYC MEF2D ST7-AS1 TES LOC102724407 LOC100506489 ENSG00000228368 LINC01392 TFEC ST7-OT4 LOC102724434 ENSG00000279086
GH07F116545 0.9 ENCODE 9.9 -406.5 -406515 2.9 CBX3 INSM2 SIN3A ZEB1 ZNF366 FOS ZNF362 SP3 YY2 ZEB2 ST7-OT4 CAV2 ENSG00000237813 CAV1 ENSG00000235427
GH07F116951 1.2 ENCODE 0.8 +0.3 305 5.0 HDGF PKNOX1 ARNT CREB3L1 WRNIP1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 ST7-AS1 CAPZA2 ST7-OT4
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ST7-OT4 on UCSC Golden Path with GeneCards custom track

Promoters for ST7-OT4 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000683149 1 2601 HDGF PKNOX1 ARNT CREB3L1 WRNIP1 ARID4B SIN3A FEZF1 DMAP1 ZNF2

Genomic Location for ST7-OT4 Gene

Chromosome:
7
Start:
116,953,899 bp from pter
End:
117,098,806 bp from pter
Size:
144,908 bases
Orientation:
Plus strand

Genomic View for ST7-OT4 Gene

Genes around ST7-OT4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ST7-OT4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ST7-OT4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ST7-OT4 Gene

Proteins for ST7-OT4 Gene

Post-translational modifications for ST7-OT4 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ST7-OT4 Gene

Domains & Families for ST7-OT4 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ST7-OT4 Gene

Function for ST7-OT4 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ST7-OT4 Gene

Localization for ST7-OT4 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ST7-OT4 gene
Compartment Confidence
extracellular 3
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ST7-OT4 Gene

Pathways & Interactions for ST7-OT4 Gene

SuperPathways for ST7-OT4 Gene

No Data Available

Interacting Proteins for ST7-OT4 Gene

Gene Ontology (GO) - Biological Process for ST7-OT4 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ST7-OT4 Gene

Transcripts for ST7-OT4 Gene

mRNA/cDNA for ST7-OT4 Gene

(2) Additional mRNA sequences :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ST7-OT4 Gene

ST7 overlapping transcript 4:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ST7-OT4 Gene

No ASD Table

Relevant External Links for ST7-OT4 Gene

GeneLoc Exon Structure for
ST7-OT4
ECgene alternative splicing isoforms for
ST7-OT4

Expression for ST7-OT4 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ST7-OT4 Gene

mRNA differential expression in normal tissues according to GTEx for ST7-OT4 Gene

This gene is overexpressed in Testis (x21.5).

SOURCE GeneReport for Unigene cluster for ST7-OT4 Gene:

Hs.662742
genes like me logo Genes that share expression patterns with ST7-OT4: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ST7-OT4 Gene

Orthologs for ST7-OT4 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for ST7-OT4 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ST7-OT4 35
  • 98 (a)
OneToOne
Species where no ortholog for ST7-OT4 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ST7-OT4 Gene

ENSEMBL:
Gene Tree for ST7-OT4 (if available)
TreeFam:
Gene Tree for ST7-OT4 (if available)

Paralogs for ST7-OT4 Gene

No data available for Paralogs for ST7-OT4 Gene

Variants for ST7-OT4 Gene

Sequence variations from dbSNP and Humsavar for ST7-OT4 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs10262671 -- 116,959,995(+) TTAAT(A/T)CTTAG intron-variant
rs111526408 -- 116,952,133(+) CGATC(A/C)TTTAC intron-variant, upstream-variant-2KB
rs111794617 -- 116,954,816(+) CTGGA(A/T)ATGCA intron-variant, upstream-variant-2KB
rs112231335 -- 116,958,062(+) GCTCA(C/T)TGCAG intron-variant
rs113895900 -- 116,954,163(+) GGCCG(C/G)GGAGG intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for ST7-OT4 Gene

Variant ID Type Subtype PubMed ID
dgv1324e214 CNV gain 21293372
esv2659068 CNV deletion 23128226
esv3576422 CNV gain 25503493
esv3614703 CNV gain 21293372
esv3614704 CNV gain 21293372
esv3614705 CNV loss 21293372
esv3891196 CNV gain 25118596
nsv1075053 CNV deletion 25765185
nsv1144198 CNV deletion 24896259
nsv7405 OTHER inversion 18451855
nsv831107 CNV gain 17160897

Variation tolerance for ST7-OT4 Gene

Gene Damage Index Score: 0.47; 10.30% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ST7-OT4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ST7-OT4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ST7-OT4 Gene

Disorders for ST7-OT4 Gene

Relevant External Links for ST7-OT4

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ST7-OT4

No disorders were found for ST7-OT4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ST7-OT4 Gene

Publications for ST7-OT4 Gene

  1. The RAY1/ST7 tumor-suppressor locus on chromosome 7q31 represents a complex multi-transcript system. (PMID: 12213198) Vincent J.B. … Scherer S.W. (Genomics 2002) 2 3 22 64
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for ST7-OT4 Gene

Sources for ST7-OT4 Gene

Content
Loading form....