ST6GALNAC6 Gene
protein-coding GIFtS: 52
GCID: GC09M130647
|
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide...(Previous name: sialytransferase 7 ((alpha-N-acetylneuraminyl 2,3-betagalactosyl-1,3)-N-acetyl...)
(Previous symbol: SIAT7F)
| |
Aliases
for ST6GALNAC6 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| ST6(Alpha-N-Acetyl-Neuraminyl-2,3-Beta-Galactosyl-1,3)-N-AcetylgalactosaminideAlpha-2,6-Sialyltransferase 61 2 | | ST6GalNAc VI2 3 | | SIAT7F1 2 3 | | RP11-203J24.32 | | ST6GALNACVI1 2 | | Alpha-N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 62 | | Sialytransferase 7 ((Alpha-N-Acetylneuraminyl 2,3-Betagalactosyl-1,3)-N-AcetylGalactosaminide Alpha-2,6-Sialytransferase) F1 2 | | CMP-NeuAC:(Beta)-N-Acetylgalactosaminide (Alpha)2,6-Sialyltransferase Member VI2 | | GalNAc Alpha-2,6-Sialyltransferase VI2 3 | | EC 2.4.99.-3 | | Sialyltransferase 7F2 3 | | ST6GalNAcVI3 | | SIAT7-F2 3 | | EC 2.4.998 | | HST6GalNAc VI2 3 | | EC 2.4.99.78 |
Export aliases for ST6GALNAC6 gene to outside databasesPrevious GC identifers: GC09M122294 GC09M124101 GC09M126023 GC09M127729 GC09M129687 GC09M100265 |
Summaries
for ST6GALNAC6 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ST6GALNAC6:
ST6GALNAC6 belongs to a family of sialyltransferases that modify proteins and ceramides on the cell surface to altercell-cell or cell-extracellular matrix interactions (Tsuchida et al., 2003 (PubMed 12668675)).(supplied by OMIM, Mar2008)
UniProtKB/Swiss-Prot: SIA7F_HUMAN, Q969X2Function: Alpha-2,6-sialyltransferase involved in the synthesis of alpha-series gangliosides. Has activity toward GD1a,GT1b and GM1b. Has no activity toward glycoproteins. Responsible for the biosynthesis of DSGG(disialylgalactosylgloboside) from MSGG (monosialylgalactosylgloboside) in normal and malignant kidney. Participatesin the synthesis of disialyl Lewis a (Le(a))
Gene Wiki entry for ST6GALNAC6
|
Genomic Views
for ST6GALNAC6 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_008470.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ST6GALNAC6 gene promoter:
MyoD XBP-1 ATF6 E47
Other transcription factors
Search SABiosciences Chromatin IP Primers for ST6GALNAC6
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ST6GALNAC6 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9q34.11 Ensembl cytogenetic band: 9q34.11 HGNC cytogenetic band: 9q34.13ST6GALNAC6 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09M130647: view genomic region
(about GC identifiers)
Start:
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130,647,600 bp from pter |
End:
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130,667,687 bp from pter |
Size:
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20,088 bases |
Orientation:
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minus strand |
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Proteins
for ST6GALNAC6 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SIA7F_HUMAN, Q969X2 (See
protein sequence)Recommended Name: Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 Size: 333 amino acids; 38068 Da
Subcellular location: Golgi apparatus membrane; Single-pass type II membrane protein (By similarity)
Miscellaneous: The carbohydrate antigen disialyl Lewis a, which is at least partly synthesized by ST6GALNAC6, is anormal counterpart of sialyl Lewis a, better known as CA19-9, an antigen widely used as a serum marker for diagnosisof cancers in the digestive track. Disialyl Lewis a is predominantly expressed in non-malignant epithelial cells ofthe digestive organs, while sialyl Lewis a is preferentially expressed in cancers. Disialyl Lewis a in normalepithelial cells serves as a ligand for immunosuppressive receptors, such as SIGLEC7 and SIGLEC9, expressed onresident monocytes/macrophages and maintains immunological homeostasis of mucosal membranes in digestive organs.Sialyl Lewis a, as well as its positional isomer sialyl Lewis x, serves as a ligand for vascular cell adhesionmolecule E-selectin and facilitates hematogenous metastasis through mediating adhesion of circulating cancer cells tovascular endothelium (PubMed:17760270)
Sequence caution: Sequence=CAI12610.1; Type=Erroneous gene model prediction; Sequence=CAI12611.1; Type=Erroneous genemodel prediction; Sequence=EAW87712.1; Type=Erroneous gene model prediction;
Secondary accessions: B3KQ01 Q5T9C4 Q5T9C5 Q9H8A2 Q9ULB8Alternative splicing: 2 isoforms: Q969X2-1 Q969X2-2 Explore the universe of human proteins at neXtProt for ST6GALNAC6: NX_Q969X2
4/5 DME Specific Peptides for ST6GALNAC6 (Q969X2) (see all 5)
ST6GALNAC6 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_038471.2
ENSEMBL proteins: ENSP00000362239 ENSP00000362234 ENSP00000362235 ENSP00000362237 ENSP00000405326 ENSP00000291839 ENSP00000438109
Human Recombinant Protein Products for ST6GALNAC6:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
ST6GALNAC6 for ontologies About GeneDecksing
ST6GALNAC6 Antibody Products:
Assay Products for ST6GALNAC6: |
Protein
Domains /
Families
for ST6GALNAC6 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ST6GALNAC6 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q969X2ProtoNet protein and cluster: Q969X2 1 Blocks protein family: IPB001675 Glycosyl transferase
UniProtKB/Swiss-Prot: SIA7F_HUMAN, Q969X2Similarity: Belongs to the glycosyltransferase 29 family |
Function
for ST6GALNAC6 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: SIA7F_HUMAN, Q969X2Function: Alpha-2,6-sialyltransferase involved in the synthesis of alpha-series gangliosides. Has activity toward GD1a,GT1b and GM1b. Has no activity toward glycoproteins. Responsible for the biosynthesis of DSGG(disialylgalactosylgloboside) from MSGG (monosialylgalactosylgloboside) in normal and malignant kidney. Participatesin the synthesis of disialyl Lewis a (Le(a))Biophysicochemical properties: Kinetic parameters: KM=0.33 mM for GM1b; KM=0.46 mM for sialyl-Lc4;Induction: Down-regulated in renal cancers Enzyme Numbers (IUBMB): EC 2.4.99.-1 EC 2.4.992 EC 2.4.99.72
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity |
ISS | -- | | GO:0008373 | sialyltransferase activity |
ISS | 12668675 |
ST6GALNAC6 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ST6GALNAC6 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ST6GALNAC6
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ST6GALNAC6 (NM_013443) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ST6GALNAC6 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ST6GALNAC6 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ST6GALNAC6 |
|
Pathways & Interactions
for ST6GALNAC6 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Ganglio Sphingolipid Metabolism | | | 2 | Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for ST6GALNAC6
2 
Kegg Pathways (Kegg details for ST6GALNAC6):
ST6GALNAC6 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ST6GALNAC6
STRING Interaction
Network Preview (showing 5 interactants - click image to see more details)
5 Interacting proteins for ST6GALNAC6 (Q969X23 ENSP000002918394) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table
ST6GALNAC6 for ontologies About GeneDecksing
|
Drugs & Compounds
for ST6GALNAC6 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ST6GALNAC6
1 HMDB Compound for ST6GALNAC6 About this table
Search CenterWatch for drugs/clinical trials and news about ST6GALNAC6 / SIA7F
|
Transcripts
for ST6GALNAC6 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ST6GALNAC6 gene: NM_013443.3 Unigene Cluster for ST6GALNAC6: ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 Hs.109672 [show with all ESTs]Unigene Representative Sequence: BC03610216 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000373146(uc004bso.1) ENST00000491678 ENST00000373141(uc004bsn.1 uc011man.1)
ENST00000373142(uc004bsp.1) ENST00000373144(uc004bsq.1) ENST00000485320
ENST00000463086 ENST00000480417 ENST00000447681 ENST00000494541 ENST00000483353
ENST00000481355 ENST00000478319 ENST00000494611 ENST00000291839(uc004bsr.2 uc010mxp.1)
ENST00000542456
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ST6GALNAC6 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ST6GALNAC6
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ST6GALNAC6 (NM_013443) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ST6GALNAC6 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ST6GALNAC6 |
Additional cDNA sequence: AB035173.1 AJ507293.1 AK023900.1 AK025959.1 AK057100.1 AK226174.1 AK300534.1 AK310850.1 AY358672.1 BC006564.2 BC007802.2 BC016299.2 BC036102.1 CR457318.1 24/29 DOTS entries (see all 29): DT.115492 DT.91758063 DT.101984750 DT.100708143 DT.100708596 DT.95138277 DT.86851844 DT.100818793 DT.100818790 DT.95138278 DT.121209803 DT.100829913 DT.91758062 DT.100818791 DT.100818795 DT.75176378 DT.100778413 DT.121209889 DT.121209904 DT.121209938 DT.121209944 DT.121209960 DT.91758064 DT.95138280 24/583 AceView cDNA sequences (see all 583): AU098415 BQ424678 BM982541 CA435785 BM991282 BU856356 BM999325 AI686021 BU167789 BX119193 BM662468 BE313808 AI833295 BM141809 AI341125 BM739235 BI838391 BP362195 AW294326 AA631095 BQ181606 F29391 BQ953448 N91906
GeneLoc Exon Structure
5/13 Alternative Splicing Database (ASD) splice patterns (SP) for ST6GALNAC6 (see all 13) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | ^ | 7 | ^ | 8a | · | 8b | · | 8c | · | 8d | · | 8e | · | 8f | · | 8g | ^ | 9 |
|---|
|
| SP1: | | | | | | | - | | - | | - | | - | | | | - | | - | | - | | - | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | - | | - | | - | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ST6GALNAC6
|
Expression
for ST6GALNAC6 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ST6GALNAC6 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGGCCTTGGT
About this image
See ST6GALNAC6 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ST6GALNAC6
SOURCE GeneReport for Unigene cluster: Hs.109672
UniProtKB/Swiss-Prot: SIA7F_HUMAN, Q969X2Tissue specificity: Expressed in kidney, in proximal tubule epithelial cells. Expressed in colon cell lines
SABiosciences Custom PCR Arrays for ST6GALNAC6
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ST6GALNAC6
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ST6GALNAC6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ST6GALNAC6 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ST6GALNAC6 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ST6GALNAC6 |
Orthologs
for ST6GALNAC6 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ST6GALNAC6 gene from 3/11 species (see all 11) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
ST6GALNAC61 |
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide more |
75.48(n)
75.25(a) |
|
425243 XM_423028.3 XP_423028.3 |
lizard
(Anolis carolinensis) |
Reptilia |
ST6GALNAC66 |
-- |
73(a) |
1 ↔ 1 |
AAWZ02039308(984-3325) |
zebrafish
(Danio rerio) |
Actinopterygii |
st6galnac61 |
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide more |
63.89(n)
55.4(a) |
|
407715 XM_690185.5 XP_695277.4 |
ENSEMBL Gene Tree for ST6GALNAC6 (if available)
TreeFam Gene Tree for ST6GALNAC6 (if available) |
Paralogs
for ST6GALNAC6 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ST6GALNAC6 gene
- ST6GALNAC32 ST6GAL22 ST6GAL12 ST6GALNAC52 ST6GALNAC42
3 SIMAP similar genes for ST6GALNAC6 using alignment to 2 protein entries: SIA7F_HUMAN (see all proteins):ST6GALNAC5 ST6GALNAC4 ST6GALNAC3
ST6GALNAC6 for paralogs About GeneDecksing
|
Genomic Variants
for ST6GALNAC6 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ST6GALNAC6 (130647600 - 130667687 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ST6GALNAC6
1 CNV: 52728 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ST6GALNAC6 |
|
Disorders
/ Diseases
for ST6GALNAC6 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ST6GALNAC6 for disorders About GeneDecksing
OMIM gene information: 610135
OMIM disorders: --
2  diseases for ST6GALNAC6: About MalaCardscolon cancer ataxia
Export disorders for ST6GALNAC6 gene to outside databases
|
Publications
for ST6GALNAC6 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ST6GALNAC6 gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with ST6GALNAC6) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Synthesis of disialyl Lewis a (Le(a)) structure in colon cancer cell lines by a sialyltransferase, ST6GalNAc VI, responsible for the synthesis of alpha-series gangliosides. (PubMed id 12668675)1, 2, 3 Tsuchida A.... Furukawa K. (2003)
- Identification and expression of a sialyltransferase responsible for the synthesis of disialylgalactosylgloboside in normal and malignant kidney cells: downregulation of ST6GalNAc VI in renal cancers. (PubMed id 17123352)1, 2 Senda M....Furukawa K. (2007)
- The animal sialyltransferases and sialyltransferase-related genes: a phylogenetic approach. (PubMed id 15843597)1, 2 Harduin-Lepers A.... Oriol R. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
- Carbohydrate antigen sialyl Lewis a--its pathophysiological significance and induction mechanism in cancer progression. (PubMed id 17760270)2 Kannagi R. (2007)
- Identification of linkage-specific sequence motifs in sialyltransferases. (PubMed id 16207893)2 Patel R.Y. and Balaji P.V. (2006)
- A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)1 Lim J.... Zoghbi H.Y. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)2 Humphray S.J.... Dunham I. (2004)
|
External Searches for ST6GALNAC6 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ST6GALNAC6 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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Other Databases showing ST6GALNAC6 gene
(According to HUGE)
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Specialized Databases showing ST6GALNAC6 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for ST6GALNAC6 | Pharmacogenomics, SNPs, Pathways | | GGDB | http://riodb.ibase.aist.go.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=ST6GALNAC6 | | Functional Glycomics Gateway - GTase | http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_635 |
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| Patent Information for ST6GALNAC6 gene:
Search GeneIP for patents involving ST6GALNAC6
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ST6GALNAC6 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ST6GALNAC6 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ST6GALNAC6 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ST6GALNAC6 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ST6GALNAC6 | | OriGene 3'-UTR Clone for ST6GALNAC6 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ST6GALNAC6 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ST6GALNAC6 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ST6GALNAC6 | | OriGene Custom Protein Services for ST6GALNAC6 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ST6GALNAC6 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ST6GALNAC6 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ST6GALNAC6 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ST6GALNAC6 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ST6GALNAC6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ST6GALNAC6 |
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 | | | ST6GALNAC6 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ST6GALNAC6 |
|  |  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ST6GALNAC6 |
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