Aliases for ST6GALNAC6 Gene
- ST6 (Alpha-N-Acetyl-Neuraminyl-2,3-Beta-Galactosyl-1,3)-N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 6 2 3
- Sialytransferase 7 ((Alpha-N-Acetylneuraminyl 2,3-Betagalactosyl-1,3)-N-Acetyl Galactosaminide Alpha-2,6-Sialytransferase) F 2 3
- GalNAc Alpha-2,6-Sialyltransferase VI 3 4
- Sialyltransferase 7F 3 4
- ST6GALNACVI 3 4
- SIAT7-F 3 4
- SIAT7F 3 4
External Ids for ST6GALNAC6 Gene
Previous HGNC Symbols for ST6GALNAC6 Gene
Previous GeneCards Identifiers for ST6GALNAC6 Gene
ST6GALNAC6 belongs to a family of sialyltransferases that modify proteins and ceramides on the cell surface to alter cell-cell or cell-extracellular matrix interactions (Tsuchida et al., 2003 [PubMed 12668675]).[supplied by OMIM, Mar 2008]
GeneCards Summary for ST6GALNAC6 Gene
ST6GALNAC6 (ST6 (Alpha-N-Acetyl-Neuraminyl-2,3-Beta-Galactosyl-1,3)-N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 6) is a Protein Coding gene. Among its related pathways are Transport to the Golgi and subsequent modification and Metabolism. GO annotations related to this gene include sialyltransferase activity and alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity. An important paralog of this gene is ST6GAL1.
UniProtKB/Swiss-Prot for ST6GALNAC6 Gene
Alpha-2,6-sialyltransferase involved in the synthesis of alpha-series gangliosides. Has activity toward GD1a, GT1b and GM1b. Has no activity toward glycoproteins. Responsible for the biosynthesis of DSGG (disialylgalactosylgloboside) from MSGG (monosialylgalactosylgloboside) in normal and malignant kidney. Participates in the synthesis of disialyl Lewis a (Le(a)).