ST6GALNAC1 Gene
protein-coding GIFtS: 51
GCID: GC17M074620
|
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide...(Previous name: sialyltransferase 7 ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl...) (Previous symbol: SIAT7A)
| |
Aliases for ST6GALNAC1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| ST6(Alpha-N-Acetyl-Neuraminyl-2,3-Beta-Galactosyl-1,3)-N-AcetylgalactosaminideAlpha-2,6-Sialyltransferase 11 2 | | ST6GalNAc I2 3 | | SIAT7A1 2 3 | | HSY113392 | | ST6GalNAcI1 2 3 | | STYI2 | | Sialyltransferase 7((Alpha-N-Acetylneuraminyl-2,3-Beta-Galactosyl-1,3)-N-Acetyl GalactosaminideAlpha-2,6-Sialyltransferase) A1 2 | | Alpha-N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 12 | | GalNAc Alpha-2,6-Sialyltransferase I2 3 | | GalNAc Alpha-2, 6-Sialyltransferase I, Long Form2 | | Sialyltransferase 7A2 3 | | EC 2.4.99.33 | | SIAT7-A2 3 | | |
Export aliases for ST6GALNAC1 gene to outside databasesPrevious GC identifers: GC17M072133 GC17M070050 |
Summaries for ST6GALNAC1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for ST6GALNAC1: Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions ofintracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkageto O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzedsialylation of GalNAc residues on mucins (Ikehara et al., 1999 (PubMed 10536037); Sewell et al., 2006 (PubMed16319059)).(supplied by OMIM, Mar 2008) Gene Wiki entry for ST6GALNAC1
|
Genomic Views for ST6GALNAC1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ST6GALNAC1 gene promoter: Nkx3-1 Nkx3-1 v4 GR-beta Nkx3-1 v1 RORalpha2 Nkx3-1 v2 Zic1 Nkx3-1 v3 GR-alpha Ik-1 Other transcription factors
Search SABiosciences Chromatin IP Primers for ST6GALNAC1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ST6GALNAC1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q25.1 Ensembl cytogenetic band: 17q25.1 HGNC cytogenetic band: 17q25.3ST6GALNAC1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M074620: view genomic region
(about GC identifiers)
Start:
|
74,620,843 bp from pter |
End:
|
74,639,920 bp from pter |
Size:
|
19,078 bases |
Orientation:
|
minus strand |
|
Proteins for ST6GALNAC1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: SIA7A_HUMAN, Q9NSC7 (See
protein sequence)Recommended Name: Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 Size: 600 amino acids; 68564 Da
Subcellular location: Golgi apparatus membrane; Single-pass type II membrane protein (Potential)
Secondary accessions: Q6UW90 Q9NSC6Explore the universe of human proteins at neXtProt for ST6GALNAC1: NX_Q9NSC7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NSC7 ST6GALNAC1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_060884.1 ENSEMBL proteins: ENSP00000465092 ENSP00000351991 ENSP00000156626 ENSP00000466230 ENSP00000466436 ENSP00000465116 ENSP00000468784 Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0030173 | integral to Golgi membrane |
IEA | -- |
ST6GALNAC1 for ontologies About GeneDecksing
ST6GALNAC1 Antibody Products: Assay Products for ST6GALNAC1: |
Protein
Domains / Families for ST6GALNAC1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ST6GALNAC1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9NSC7ProtoNet protein and cluster: Q9NSC7 1 Blocks protein family: IPB001675 Glycosyl transferase
UniProtKB/Swiss-Prot: SIA7A_HUMAN, Q9NSC7Similarity: Belongs to the glycosyltransferase 29 family |
Function for ST6GALNAC1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: SIA7A_HUMAN, Q9NSC7Catalytic activity: CMP-N-acetylneuraminate + glycano-(1->3)-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein = CMP +glycano-((2->6)-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoproteinEnzyme Number (IUBMB): EC 2.4.99.31
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ST6GALNAC1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ST6GALNAC1 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ST6GALNAC1 (NM_018414) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ST6GALNAC1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ST6GALNAC1  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ST6GALNAC1 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity |
IEA | -- | | GO:0008373 | sialyltransferase activity |
NAS | 10536037 |
ST6GALNAC1 for ontologies About GeneDecksing
|
Pathways & Interactions for ST6GALNAC1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Metabolism | | | 2 | Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein | |
Pathway sources See GeneCards unified pathways Show all pathways
2
Kegg Pathways (Kegg details for ST6GALNAC1): UniProtKB/Swiss-Prot: SIA7A_HUMAN, Q9NSC7Pathway: Protein modification; protein glycosylation
ST6GALNAC1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ST6GALNAC1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/25 Interacting proteins for ST6GALNAC1 (ENSP000001566264) via UniProtKB, MINT, STRING, and/or I2D (see all 25) About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
ST6GALNAC1 for ontologies About GeneDecksing
|
Drugs & Compounds for ST6GALNAC1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ST6GALNAC1 for compounds About GeneDecksing
Browse Tocris compounds for ST6GALNAC1 1 Novoseek chemical compound relationship for ST6GALNAC1 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| sialic acid |
72 |
2 |
15770530 (1), 16135558 (1) |
Search CenterWatch for drugs/clinical trials and news about ST6GALNAC1 / SIA7A 
|
Transcripts for ST6GALNAC1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for ST6GALNAC1 gene: NM_018414.3 Unigene Cluster for ST6GALNAC1: ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 Hs.105352 [show with all ESTs]Unigene Representative Sequence: BC06383011 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000592042 ENST00000359088 ENST00000156626(uc002jsh.3 uc002jsi.3 uc002jsj.3) ENST00000585633 ENST00000588375 ENST00000590784 ENST00000589004 ENST00000590878 ENST00000589813 ENST00000590915 ENST00000589992
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ST6GALNAC1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ST6GALNAC1 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ST6GALNAC1 (NM_018414) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ST6GALNAC1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ST6GALNAC1  |
Additional cDNA sequence: AK000113.1 AK310906.1 AY096001.1 AY358918.1 BC022462.1 BC063830.1 Y11339.2 8 DOTS entries: DT.95167162 DT.100023579 DT.305981 DT.436637 DT.100787208 DT.97843343 DT.100787212 DT.97783275 24/109 AceView cDNA sequences (see all 109): AL544554 CA432681 CB156507 AY358918 BG984953 BX951360 BG982591 AA514491 CB130001 AY096001 BG982580 BC063830 BG982660 AI858216 CB147534 AA494414 CF139911 CB243428 BX089008 AL709089 AI858970 AL556596 BU190870 Y11339 GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for ST6GALNAC1 (see all 7) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | ^ | 12a | · | 12b | |
| SP1: | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | - |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for ST6GALNAC1
|
Expression for ST6GALNAC1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ST6GALNAC1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: GAAAGGCAAA
About this image See ST6GALNAC1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ST6GALNAC1
SOURCE GeneReport for Unigene cluster: Hs.105352 SABiosciences Expression via Pathway-Focused PCR Array including ST6GALNAC1:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ST6GALNAC1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ST6GALNAC1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ST6GALNAC1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ST6GALNAC1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ST6GALNAC1 |
Orthologs for ST6GALNAC1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ST6GALNAC1 gene from 3/10 species (see all 10) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
ST6GALNAC11 |
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide more |
67.31(n) 64.27(a) |
  |
396168 NM_205240.1 NP_990571.1 |
lizard (Anolis carolinensis) |
Reptilia |
ST6GALNAC16 |
-- |
66(a) |
1 ↔ 1 |
2(111815826-111829428) |
zebrafish (Danio rerio) |
Actinopterygii |
st6galnac1.11 |
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide more |
52.78(n) 47.85(a) |
  |
564336 XM_003199600.1 XP_003199648.1 |
ENSEMBL Gene Tree for ST6GALNAC1 (if available) TreeFam Gene Tree for ST6GALNAC1 (if available)  |
Paralogs for ST6GALNAC1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for ST6GALNAC1 gene
- ST3GAL32 ST3GAL62 ST6GALNAC22 ST3GAL12 ST3GAL42 ST3GAL52 ST3GAL22
2 SIMAP similar genes for ST6GALNAC1 using alignment to 7 protein entries: SIA7A_HUMAN (see all proteins):ST6GALNAC2 ST3GAL1
ST6GALNAC1 for paralogs About GeneDecksing
|
Genomic Variants for ST6GALNAC1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 17 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for ST6GALNAC1 (74620843 - 74639920 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for ST6GALNAC1 1 CNV: 58816  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ST6GALNAC1 |
|
Disorders
/ Diseases for ST6GALNAC1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ST6GALNAC1 for disorders About GeneDecksing
OMIM gene information: 610138
OMIM disorders: --
3 diseases for ST6GALNAC1: About MalaCardscolon adenocarcinoma breast cancer adenocarcinoma
2 Novoseek disease relationships for ST6GALNAC1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| breast cancer |
33.5 |
7 |
16135558 (4), 12820722 (2), 15770530 (1) |
| colorectal cancer |
28.3 |
1 |
15539921 (1) |
Human Genome Epidemiology (HuGE) Navigator: ST6GALNAC1 (1 document) Export disorders for ST6GALNAC1 gene to outside databases
|
Publications for ST6GALNAC1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ST6GALNAC1 gene, integrated from 9 sources (see all 18): (articles sorted by number of sources associating them with ST6GALNAC1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Cloning and expression of a human gene encoding an N- acetylgalactosamine-alpha2,6-sialyltransferase (ST6GalNac I); a candidate for synthesis of cancer-associated sialyl-Tnantigens. (PubMed id 10536037)1, 2, 9 Ikehara Y.... Narimatsu H. (1999)
- Expression of sialyl-Tn antigen in breast cancer cells transfected with the human CMP-Neu5Ac: GalNAc alpha2,6-sialyltransferase (ST6GalNac I) cDNA. (PubMed id 12820722)1, 2, 9 Julien S.... Delannoy P. (2001)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
- The ST6GalNAc-I sialyltransferase localizes throughout the Golgi and is responsible for the synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer. (PubMed id 16319059)1, 9 Sewell R....Taylor-Papadimitriou J. (2006)
- Enhancement of metastatic ability by ectopic expressio n of ST6GalNAcI on a gastric cancer cell line in a mouse model. (PubMed id 22228572)1 Ozaki H....Narimatsu H. (2012)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Golgi N-glycosyltransferases form both homo- and hete rodimeric enzyme complexes in live cells. (PubMed id 20378551)1 Hassinen A....Kellokumpu S. (2010)
- Prognostic utility of glycosyltransferase expression in breast cancer. (PubMed id 19287074)1 Patani N....Mokbel K. (2008)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
|
External Searches for ST6GALNAC1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing ST6GALNAC1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ST6GALNAC1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ST6GALNAC1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for ST6GALNAC1 | Pharmacogenomics, SNPs, Pathways | | ATLAS Chromosomes in Cancer entry for ST6GALNAC1 | Genetics and Cytogenetics in Oncology and Haematology | | GGDB | http://riodb.ibase.aist.go.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=ST6GALNAC1 | | Functional Glycomics Gateway - GTase | http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_630 |
|
| | |
About This Section
| Patent Information for ST6GALNAC1 gene: Search GeneIP for patents involving ST6GALNAC1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for ST6GALNAC1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for ST6GALNAC1 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ST6GALNAC1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ST6GALNAC1 | | OriGene Protein Over-expression Lysate for ST6GALNAC1 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for ST6GALNAC1 | | OriGene 3'-UTR Clone for ST6GALNAC1 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ST6GALNAC1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ST6GALNAC1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for ST6GALNAC1 | | OriGene Custom Protein Services for ST6GALNAC1 | | OriGene Custom Immunoassay Development | | |
| |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ST6GALNAC1 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ST6GALNAC1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ST6GALNAC1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ST6GALNAC1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ST6GALNAC1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ST6GALNAC1 |
| |
 |  |  |  | |
| | | |  |  |  |  | | | | |
 |
 |
 |
 | | ST6GALNAC1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ST6GALNAC1 |
|  |  |  | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ST6GALNAC1 |
|
|
|
|