Aliases for ST6GAL2 Gene
External Ids for ST6GAL2 Gene
Previous Symbols for ST6GAL2 Gene
This locus encodes a sialyltransferase. The encoded type II transmembrane protein catalyzes the transfer of sialic acid from CMP to an oligosaccharide substrate. Polymorphisms at this locus may be associated with variations in risperidone response in schizophrenic patients. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012]
GeneCards Summary for ST6GAL2 Gene
ST6GAL2 (ST6 Beta-Galactosamide Alpha-2,6-Sialyltranferase 2) is a Protein Coding gene. Among its related pathways are Metabolism and Other types of O-glycan biosynthesis. GO annotations related to this gene include beta-galactoside alpha-2,6-sialyltransferase activity. An important paralog of this gene is ST6GAL1.
UniProtKB/Swiss-Prot for ST6GAL2 Gene
Transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates. Has alpha-2,6-sialyltransferase activity toward oligosaccharides that have the Gal-beta-1,4-GlcNAc sequence at the non-reducing end of their carbohydrate groups, but it has weak or no activities toward glycoproteins and glycolipids