Aliases for ST6GAL1 Gene
External Ids for ST6GAL1 Gene
Previous HGNC Symbols for ST6GAL1 Gene
Previous GeneCards Identifiers for ST6GAL1 Gene
This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described. [provided by RefSeq, Aug 2009]
GeneCards Summary for ST6GAL1 Gene
ST6GAL1 (ST6 Beta-Galactosamide Alpha-2,6-Sialyltranferase 1) is a Protein Coding gene. Diseases associated with ST6GAL1 include colon adenocarcinoma and cervical cancer, somatic. Among its related pathways are Transport to the Golgi and subsequent modification and Metabolism. GO annotations related to this gene include sialyltransferase activity and beta-galactoside alpha-2,6-sialyltransferase activity. An important paralog of this gene is ST6GAL2.
UniProtKB/Swiss-Prot for ST6GAL1 Gene
Transfers sialic acid from CMP-sialic acid to galactose-containing acceptor substrates.