Aliases for ST6GAL1 Gene
- SIAT1 3 4
- CMP-N-Acetylneuraminate Beta-Galactosamide Alpha-2,6-Sialyltransferase 3
- Sialyltransferase 1 (Beta-Galactoside Alpha-2,6-Sialyltransferase) 3
- Sialyltransferase 1 (Beta-Galactoside Alpha-2,6-Sialytransferase) 2
- ST6 N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 1 2
- Sialyltransferase 1 4
- ST6N 3
External Ids for ST6GAL1 Gene
Previous HGNC Symbols for ST6GAL1 Gene
Previous GeneCards Identifiers for ST6GAL1 Gene
This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described. [provided by RefSeq, Aug 2009]
GeneCards Summary for ST6GAL1 Gene
ST6GAL1 (ST6 Beta-Galactoside Alpha-2,6-Sialyltransferase 1) is a Protein Coding gene. Diseases associated with ST6GAL1 include Colon Adenocarcinoma and Colorectal Cancer. Among its related pathways are Transport to the Golgi and subsequent modification and Synthesis of substrates in N-glycan biosythesis. GO annotations related to this gene include sialyltransferase activity and beta-galactoside alpha-2,6-sialyltransferase activity. An important paralog of this gene is ST6GALNAC4.
UniProtKB/Swiss-Prot for ST6GAL1 Gene
Transfers sialic acid from CMP-sialic acid to galactose-containing acceptor substrates.