ST5 Gene
protein-coding GIFtS: 53
GCID: GC11M008714
|
|
suppression of tumorigenicity 5
| |
Aliases
for ST5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Suppression Of Tumorigenicity 51 2 | | HeLa Tumor Suppression 12 3 | | HTS11 2 3 5 | | DENN/MADD Domain Containing 2B2 | | DENND2B1 2 3 | | Suppression Of Tumorigenicity 5 Protein2 | | P1261 | | DENN Domain-Containing Protein 2B3 |
Export aliases for ST5 gene to outside databasesPrevious GC identifers: GC11M009485 GC11M009161 GC11M008754 GC11M008679 GC11M008671 GC11M008382 |
Summaries
for ST5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ST5:
This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encodedby this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins.This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase,which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively splicedtranscript variants of this gene encoding distinct isoforms are identified. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: ST5_HUMAN, P78524Function: Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP toGTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May be involved in cytoskeletalorganization and tumorogenicity. Isoform 1 seems to be involved in a signaling transduction pathway leading toactivation of MAPK1/ERK2. Isoform 3 may block ERK2 activation stimulated by ABL1. Isoform 3 may alter cell morphologyand cell growth
Gene Wiki entry for ST5
|
Genomic Views
for ST5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_009237.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ST5 gene promoter:
ATF-2 c-Jun HNF-4alpha1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ST5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ST5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11p15 Ensembl cytogenetic band: 11p15.4 HGNC cytogenetic band: 11p15ST5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M008714: view genomic region
(about GC identifiers)
Start:
|
8,714,898 bp from pter |
End:
|
8,932,498 bp from pter |
Size:
|
217,601 bases |
Orientation:
|
minus strand |
|
Proteins
for ST5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ST5_HUMAN, P78524 (See
protein sequence)Recommended Name: Suppression of tumorigenicity 5 protein Size: 1137 amino acids; 126485 Da
Subunit: Isoform 1 interacts with the SH3 domain of ABL1
Sequence caution: Sequence=AAC50925.1; Type=Frameshift; Positions=159, 169;
Secondary accessions: B2R6X7 B3KXQ6 P78523 Q16492 Q7KYY2 Q7KZ12 Q8NE12 Q9BQQ6Alternative promoter usage, Alternative splicing: 3 isoforms: P78524-1 P78524-2 P78524-3 (Produced by alternative promoter usage)Explore the universe of human proteins at neXtProt for ST5: NX_P78524
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P78524
ST5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_005409.3 NP_631896.1 NP_998783.1
ENSEMBL proteins: ENSP00000435097 ENSP00000433528 ENSP00000319678 ENSP00000432887 ENSP00000436808 ENSP00000435986 ENSP00000433349 ENSP00000436802 ENSP00000433043 ENSP00000436067 ENSP00000433588 ENSP00000435016 ENSP00000433793 ENSP00000437096 ENSP00000431580 ENSP00000433858 ENSP00000437006 ENSP00000431564 ENSP00000434701 ENSP00000432521 ENSP00000436506 ENSP00000435292 ENSP00000436760 ENSP00000433647 ENSP00000431252 ENSP00000434935 ENSP00000433346 ENSP00000433008 ENSP00000431332 ENSP00000431139 ENSP00000432872 ENSP00000431673 ENSP00000434332 ENSP00000431990 ENSP00000435228 ENSP00000436748 ENSP00000434930 ENSP00000435925 ENSP00000435180 ENSP00000435562 ENSP00000433175 ENSP00000436363 ENSP00000436154 ENSP00000350294
Human Recombinant Protein Products:
ST5 Antibody Products:
Assay Products for ST5: |
Protein
Domains /
Families
for ST5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ST5 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P78524ProtoNet protein and cluster: P78524 UniProtKB/Swiss-Prot: ST5_HUMAN, P78524Similarity: Contains 1 dDENN domainSimilarity: Contains 1 DENN domainSimilarity: Contains 1 uDENN domain |
Function
for ST5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ST5_HUMAN, P78524Function: Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP toGTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May be involved in cytoskeletalorganization and tumorogenicity. Isoform 1 seems to be involved in a signaling transduction pathway leading toactivation of MAPK1/ERK2. Isoform 3 may block ERK2 activation stimulated by ABL1. Isoform 3 may alter cell morphologyand cell growth
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ST5 (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ST5 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ST5 (NM_001900) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ST5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ST5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ST5 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0017112 | Rab guanyl-nucleotide exchange factor activity |
IDA | -- |
ST5 for ontologies About GeneDecksing
|
Pathways & Interactions
for ST5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ST5
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
5 Interacting proteins for ST5 (P785242, 3 ENSP000003196784) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0070374 | positive regulation of ERK1 and ERK2 cascade |
IDA | 9632734 |
ST5 for ontologies About GeneDecksing
|
Drugs & Compounds
for ST5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ST5
Search CenterWatch for drugs/clinical trials and news about ST5
|
Transcripts
for ST5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ST5 gene (3 alternative transcripts): NM_005418.3 NM_139157.2 NM_213618.1 Unigene Cluster for ST5: Suppression of tumorigenicity 5 Hs.117715 [show with all ESTs]Unigene Representative Sequence: NM_00541818/61 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 61): ENST00000526757(uc001mgu.3) ENST00000534127(uc001mgv.3) ENST00000313726(uc001mgt.3 uc009yfr.3)
ENST00000530991(uc010rbp.2) ENST00000526099 ENST00000527540 ENST00000532162
ENST00000534278 ENST00000524513 ENST00000530438 ENST00000532738 ENST00000526062
ENST00000532871 ENST00000533081 ENST00000526701(uc009yfs.3) ENST00000530922
ENST00000530559 ENST00000533020
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ST5 (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ST5 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ST5 (NM_001900) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ST5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ST5 |
Additional cDNA sequence: AK123380.1 AK126554.1 AK127763.1 AK293245.1 AK302824.1 AK307617.1 AK309929.1 AK312305.1 AK312758.1 BC036655.1 BX647431.1 BX647474.1 S45936.1 U15131.1 U15779.1 U15780.1 24/35 DOTS entries (see all 35): DT.91832935 DT.100785453 DT.101981184 DT.455736 DT.92438514 DT.100785460 DT.75188964 DT.100785456 DT.120726121 DT.99977160 DT.95148226 DT.120726016 DT.120726172 DT.97795613 DT.95148234 DT.100785461 DT.120726144 DT.120726150 DT.86853926 DT.92039293 DT.92438516 DT.100739170 DT.100785458 DT.120725943 24/301 AceView cDNA sequences (see all 301): BM471052 AI269509 AI270279 AI312826 AW300796 BU754177 BE045970 BU528932 AL043546 AU139710 AU122048 BE048030 F04298 BI918349 NM_005418 BQ024951 AI656411 F08064 NM_213618 AA131380 CD620474 BX472075 BU070318 BQ003360
GeneLoc Exon Structure
5/30 Alternative Splicing Database (ASD) splice patterns (SP) for ST5 (see all 30) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | · | 6e | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | · | 14c | · | 14d | · | 14e | · | 14f | · | 14g | · |
|---|
|
| SP1: | | | - | | - | | - | | - | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | - | | - | | - | | - | | - | | - | | - | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 14h | · | 14i | · | 14j | ^ | 15a | · | 15b | · | 15c | ^ | 16a | · | 16b | ^ | 17 | ^ | 18 | ^ | 19a | · | 19b | · | 19c | ^ | 20a | · | 20b | ^ | 21 | ^ | 22 | ^ | 23a | · | 23b | · | 23c | ^ | 24 | ^ | 25a | · | 25b | ^ | 26 | ^ | 27 | ^ | 28 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | - | | | | - | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | - | | | | - | | | | | | |
| SP3: | - | | - | | - | | - | | - | | - | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | - | | | | - | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | - | | | | - | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 29a | · | 29b | ^ | 30 | ^ | 31a | · | 31b | ^ | 32a | · | 32b | ^ | 33 | ^ | 34a | · | 34b | ^ | 35a | · | 35b | · | 35c | ^ | 36 | ^ | 37a | · | 37b |
|---|
|
| SP1: | | | | | - | | | | | | - | | | | - | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | | | - | | | | - | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | - | | | | | | - | | | | - | | - | | | | | | | | | | | | | | | | |
| SP4: | | | | | - | | | | | | - | | | | - | | - | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | | | - | | - | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ST5
|
Expression
for ST5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ST5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGAAGCCCAC
About this image
See ST5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ST5
SOURCE GeneReport for Unigene cluster: Hs.117715
UniProtKB/Swiss-Prot: ST5_HUMAN, P78524Tissue specificity: Widely expressed with the exception of peripheral blood lymphocytes. Isoform 1 is expressed inseveral epithelial and fibroblast (including tumorigenic) but absent in lymphoid cell lines (at protein level).Isoform 3 is expressed in primary cell or weakly tumorigenic but not in tumorigenic cell lines (at protein level)
SABiosciences Custom PCR Arrays for ST5
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ST5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ST5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ST5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ST5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ST5 |
Orthologs
for ST5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ST5 gene from 4/15 species (see all 15) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
ST51 |
suppression of tumorigenicity 5 |
74.43(n)
81.63(a) |
|
423055 XM_420988.2 XP_420988.2 |
lizard
(Anolis carolinensis) |
Reptilia |
ST56 |
-- |
78(a) |
1 ↔ 1 |
1(64657751-64730118) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.19162 |
Xenopus laevis transcribed sequence with strong similarity more |
80.08(n) |
|
CF285575.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.163062 |
Transcribed sequence with moderate similarity to protein more |
79.74(n) |
|
CK030181.1 |
ENSEMBL Gene Tree for ST5 (if available)
TreeFam Gene Tree for ST5 (if available) |
Paralogs
for ST5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ST5 gene
- DENND5A2 DENND2D2 DENND2A2 DENND32 DENND4A2 DENND1C2 DENND4B2 DENND1B2
- DENND1A2 DENND5B2 DENND4C2 DENND2C2
6 SIMAP similar genes for ST5 using alignment to 38 protein entries: ST5_HUMAN (see all proteins):DKFZp667I053 DENND2A DENND2D DENND2C DENND5B DENND1B
ST5 for paralogs About GeneDecksing
|
Genomic Variants
for ST5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ST5 (8714898 - 8932498 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ST5
1 CNV: 3837
Human Gene Mutation Database (HGMD): ST5
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ST5 |
|
Disorders
/ Diseases
for ST5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ST5 for disorders About GeneDecksing
OMIM gene information: 140750
OMIM disorders: --
7  diseases for ST5: About MalaCardsacute chest syndrome oral candidiasis candidiasis fanconi's anemia
meningitis mastitis anemia
3 diseases from the University of Copenhagen DISEASES database for ST5:Meningitis Candidiasis Mastitis Human Genome Epidemiology (HuGE) Navigator: ST5 (1 document)
Export disorders for ST5 gene to outside databases
|
Publications
for ST5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ST5 gene, integrated from 9 sources (see all 18):
(articles sorted by number of sources associating them with ST5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of a human chromosome 11 gene which is differentially regulated in tumorigenic and nontumorigenic somatic cell hybrids of HeLa cells. (PubMed id 1390339)1, 2, 3 Lichy J.H.... Howley P.M. (1992)
- Activation of extracellular signal-regulated kinase 2 by a novel Abl- binding protein, ST5. (PubMed id 9632734)1, 2, 9 Majidi M.... Lichy J.H. (1998)
- Differential expression of the human ST5 gene in HeLa-fibroblast hybrid cell lines mediated by YY1: evidence that YY1 plays a part in tumor suppression. (PubMed id 8972856)1, 2, 9 Lichy J.H.... Tsai M.M. (1996)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Comparative genomic sequencing reveals a strikingly similar architecture of a conserved syntenic region on human chromosome 11p15.3 (including gene ST5) and mouse chromosome 7. (PubMed id 11528127)1, 2 Amid C.... Schmidt E.R. (2001)
- Expression of an isoform of the novel signal transduction protein ST5 is linked to cell morphology. (PubMed id 10229203)1, 2 Hubbs A.E.... Lichy J.H. (1999)
- Deletion of the COOH terminus converts the ST5 p70 protein from an inhibitor of RAS signaling to an activator with transforming activity in NIH-3T3 cells. (PubMed id 10692462)1, 9 Majidi M....Lichy J.H. (2000)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Disruption of ST5 is associated with mental retardati on and multiple congenital anomalies. (PubMed id 19843505)1 GAPhring I....Rauch A. (2010)
- Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors. (PubMed id 20937701)2 Yoshimura S.... Barr F.A. (2010)
|
External Searches for ST5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing ST5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing ST5 gene
(According to HUGE)
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Specialized Databases showing ST5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Patent Information for ST5 gene:
Search GeneIP for patents involving ST5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ST5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ST5 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ST5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ST5 | | | OriGene Protein Over-expression Lysate for ST5 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ST5 | | OriGene 3'-UTR Clone for ST5 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ST5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ST5 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ST5 | | OriGene Custom Protein Services for ST5 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ST5 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ST5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ST5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ST5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ST5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ST5 |
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| | | | Search Tocris compounds for ST5 |
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 | | | ST5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ST5 |
|  |  |  | | | | Search ThermoFisher Antibodies for ST5 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ST5 |
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