Aliases for ST3GAL6 Gene
Aliases for ST3GAL6 Gene
External Ids for ST3GAL6 Gene
- HGNC: 18080
- Entrez Gene: 10402
- Ensembl: ENSG00000064225
- OMIM: 607156
- UniProtKB: Q9Y274
Previous HGNC Symbols for ST3GAL6 Gene
- SIAT10
Previous GeneCards Identifiers for ST3GAL6 Gene
- GC03P099935
- GC03P098451
- GC03P095823
Summaries for ST3GAL6 Gene
-
The protein encoded by this gene is a member of the sialyltransferase family. Members of this family are enzymes that transfer sialic acid from the activated cytidine 5'-monophospho-N-acetylneuraminic acid to terminal positions on sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. This protein has high specificity for neolactotetraosylceramide and neolactohexaosylceramide as glycolipid substrates and may contribute to the formation of selectin ligands and sialyl Lewis X, a carbohydrate important for cell-to-cell recognition and a blood group antigen. [provided by RefSeq, Apr 2016]
GeneCards Summary for ST3GAL6 Gene
ST3GAL6 (ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 6) is a Protein Coding gene. Diseases associated with ST3GAL6 include Sialuria. Among its related pathways are Keratan sulfate/keratin metabolism and Glycosaminoglycan metabolism. Gene Ontology (GO) annotations related to this gene include sialyltransferase activity and beta-galactoside alpha-2,3-sialyltransferase activity. An important paralog of this gene is ST3GAL4.
UniProtKB/Swiss-Prot for ST3GAL6 Gene
-
Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3-sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1.
Additional gene information for ST3GAL6 Gene
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ST3GAL6 Gene
Genomics for ST3GAL6 Gene
GeneHancer (GH) Regulatory Elements for ST3GAL6 Gene
Promoters and enhancers for ST3GAL6 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around ST3GAL6 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for ST3GAL6 Gene
Genomic Locations for ST3GAL6 Gene
- chr3:98,732,236-98,821,201
- (GRCh38/hg38)
- Size:
- 88,966 bases
- Orientation:
- Plus strand
- chr3:98,451,080-98,540,045
- (GRCh37/hg19)
Genomic View for ST3GAL6 Gene
Genes around ST3GAL6 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 3q12.1 by Ensembl
- 3q12.1 by Entrez Gene
- 3q12.1 by HGNC
ST3GAL6 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ST3GAL6 Gene
Proteins for ST3GAL6 Gene
-
Protein details for ST3GAL6 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9Y274-SIA10_HUMAN
- Recommended name:
- Type 2 lactosamine alpha-2,3-sialyltransferase
- Protein Accession:
- Q9Y274
- B2RCH2
- B3KMI1
- D3DN39
- F8W6U0
Protein attributes for ST3GAL6 Gene
- Size:
- 331 amino acids
- Molecular mass:
- 38214 Da
- Quaternary structure:
- No Data Available
Protein Expression for ST3GAL6 Gene
Selected DME Specific Peptides for ST3GAL6 Gene
- Q9Y274:
-
- QKPKHPTTGIIA
- YHNVTAEQLFLKDIIEKN
- RLFYPES
- LSKLQSCDL
- YGSDKFDLPYGM
- IDSYDVIIRMNNGPVLGHEEEVG
- CVVVGNGGVLKNKTLG
- EVHLAGFKYNF
- PALNLIYKPYQIRILDP
- GYLVAIFLS
- AIFLSAVFLYYVLHCILW
- HQFHPFLCAA
- CVVVGNG
- SPLHYYGNATMSLM
Post-translational modifications for ST3GAL6 Gene
- Glycosylation at isoforms=129, isoforms=2181, isoforms=2282, isoforms=2295, isoforms=2308, and posLast=327327
Other Protein References for ST3GAL6 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for ST3GAL6
- Novus Biologicals Antibodies for ST3GAL6
-
Abcam antibodies for ST3GAL6
- Invitrogen Antibodies for ST3GAL6
- Search GeneTex for Antibodies for ST3GAL6
-
Custom Antibody ServicesProSci Antibodies for ST3GAL6
Protein Products
-
OriGene Purified Proteins for ST3GAL6
- Search Origene for MassSpec and Protein Over-expression Lysates for ST3GAL6
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-
Abcam proteins for ST3GAL6
Assay Products
Domains & Families for ST3GAL6 Gene
Gene Families for ST3GAL6 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for ST3GAL6 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ST3GAL6 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9Y274- Family:
-
- Belongs to the glycosyltransferase 29 family.
Function for ST3GAL6 Gene
Molecular function for ST3GAL6 Gene
- UniProtKB/Swiss-Prot Function:
- Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3-sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1.
Enzyme Numbers (IUBMB) for ST3GAL6 Gene
Phenotypes From GWAS Catalog for ST3GAL6 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity | TAS | -- |
| GO:0008373 | sialyltransferase activity | IEA | -- |
| GO:0016740 | transferase activity | IEA | -- |
| GO:0016757 | transferase activity, transferring glycosyl groups | IEA | -- |
| GO:0052798 | beta-galactoside alpha-2,3-sialyltransferase activity | IDA | 10206952 |
Phenotypes for ST3GAL6 Gene
- MGI mutant phenotypes for ST3GAL6:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ST3GAL6:
Animal Models for ST3GAL6 Gene
- MGI Knock Outs for ST3GAL6:
-
- St3gal6 tm1.1Jxm
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ST3GAL6
-
-
ViGene Biosciences lentiviral particle packaged cDNA for ST3GAL6 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ST3GAL6 gene
- Search ViGene Biosciences for ST3GAL6
CRISPR Products
-
OriGene CRISPR knockouts for ST3GAL6
- genomics-online: gRNA clones - Search results for available ST3GAL6 gene related products
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-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ST3GAL6
- GenScript: Design CRISPR guide RNA sequences for ST3GAL6
miRNA for ST3GAL6 Gene
- miRTarBase miRNAs that target ST3GAL6
miRNA Products
- Search ViGene Biosciences for ST3GAL6
Inhibitory RNA Products
- Origene RNAi and shrna products in human, mouse, rat for ST3GAL6
- Browse OriGene Inhibitory RNA Products For ST3GAL6
- genomics-online: shRNA clones - Search results for available ST3GAL6 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for ST3GAL6 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ST3GAL6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ST3GAL6
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for ST3GAL6
- genomics-online: cdna clones - Search results for available ST3GAL6 gene related products
- orf clones - Search results for available ST3GAL6 gene related products
- Applied Biological Materials Clones for ST3GAL6
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
- R&D Systems cDNA Clones for ST3GAL6
Cell Line Products
-
Horizon Cell Lines for ST3GAL6
-
ViGene Biosciences adenoviral particle packaged cDNA for ST3GAL6 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ST3GAL6 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ST3GAL6 gene
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ST3GAL6 Gene
Localization for ST3GAL6 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ST3GAL6 Gene
- Golgi apparatus membrane; Single-pass type II membrane protein.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| golgi apparatus | 5 |
| endoplasmic reticulum | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | -- |
| GO:0005794 | Golgi apparatus | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA,NAS | 10206952 |
| GO:0070062 | extracellular exosome | HDA,IDA | 19199708 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for ST3GAL6 Gene
Pathways & Interactions for ST3GAL6 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Synthesis of substrates in N-glycan biosythesis | ||
| 2 | Metabolism |
.37
|
|
| 3 | Glycosaminoglycan metabolism | ||
| 4 | Keratan sulfate/keratin metabolism | ||
| 5 | Metabolism of proteins | ||
Pathways by source for ST3GAL6 Gene
2 KEGG pathways for ST3GAL6 Gene
Interacting Proteins for ST3GAL6 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006464 | cellular protein modification process | IDA | 10206952 |
| GO:0006486 | protein glycosylation | IEA | -- |
| GO:0006664 | glycolipid metabolic process | IDA | 10206952 |
| GO:0009311 | oligosaccharide metabolic process | IDA | 10206952 |
| GO:0018146 | keratan sulfate biosynthetic process | TAS | -- |
No data available for SIGNOR curated interactions for ST3GAL6 Gene
Drugs & Compounds for ST3GAL6 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Cytidine monophosphate | Experimental | Pharma | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| Cytidine monophosphate N-acetylneuraminic acid |
|
22-12-8 |
|
|||
| Sialyl-Lewis X |
|
98603-84-0 |
|
Transcripts for ST3GAL6 Gene
mRNA/cDNA for ST3GAL6 Gene
- (18) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (155) Selected AceView cDNA sequences:
- (28) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ST3GAL6 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ST3GAL6
- genomics-online: gRNA clones - Search results for available ST3GAL6 gene related products
- Applied Biological Materials CRISPR for ST3GAL6
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ST3GAL6
- GenScript: Design CRISPR guide RNA sequences for ST3GAL6
miRNA Products
- Search ViGene Biosciences for ST3GAL6
Inhibitory RNA Products
- Origene RNAi and shrna products in human, mouse, rat for ST3GAL6
- Browse OriGene Inhibitory RNA Products For ST3GAL6
- genomics-online: shRNA clones - Search results for available ST3GAL6 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for ST3GAL6 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ST3GAL6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ST3GAL6
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for ST3GAL6
- genomics-online: cdna clones - Search results for available ST3GAL6 gene related products
- orf clones - Search results for available ST3GAL6 gene related products
- Applied Biological Materials Clones for ST3GAL6
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
- R&D Systems cDNA Clones for ST3GAL6
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | ^ | 15 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP11: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP13: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP14: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP15: |
| ExUns: | 16 | ^ | 17 | ^ | 18a | · | 18b | · | 18c | · | 18d | · | 18e | · | 18f |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||
| SP2: | |||||||||||||||
| SP3: | |||||||||||||||
| SP4: | |||||||||||||||
| SP5: | |||||||||||||||
| SP6: | |||||||||||||||
| SP7: | |||||||||||||||
| SP8: | |||||||||||||||
| SP9: | |||||||||||||||
| SP10: | |||||||||||||||
| SP11: | |||||||||||||||
| SP12: | |||||||||||||||
| SP13: | |||||||||||||||
| SP14: | |||||||||||||||
| SP15: |
Expression for ST3GAL6 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Kidney (Urinary System)
- Podocytes Podocyte Layer
- Renal Vesicle
- Inner Cell Mass (Early Embryonic Tissues)
-
Blood (Hematopoietic System)
- Granulocytes Peripheral Blood
-
Epithelial Cells
- Podocytes Podocyte Layer
- Neural Tube (Nervous System)
mRNA differential expression in normal tissues according to GTEx for ST3GAL6 Gene
This gene is overexpressed in Liver (x5.6) and Heart - Left Ventricle (x4.7).
This gene is overexpressed in Peripheral blood mononuclear cells (30.3), Serum (27.4), and Placenta (8.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ST3GAL6 Gene
NURSA nuclear receptor signaling pathways regulating expression of ST3GAL6 Gene:
ST3GAL6SOURCE GeneReport for Unigene cluster for ST3GAL6 Gene:
Hs.148716mRNA Expression by UniProt/SwissProt for ST3GAL6 Gene:
Q9Y274-SIA10_HUMAN
Tissue specificity:
Ubiquitous.
Evidence on tissue expression from TISSUES for ST3GAL6 Gene
- Liver(4.3)
- Nervous system(4.3)
Primer Products
-
OriGene qPCR primer pairs for ST3GAL6
-
OriGene qPCR primer pairs and template standards for ST3GAL6
- genomics-online: primer clones - Search results for available ST3GAL6 gene related products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for ST3GAL6 Gene
Orthologs for ST3GAL6 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ST3GAL6 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | ST3GAL6 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | ST3GAL6 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | St3gal6 16 34 33 |
|
||
| rat (Rattus norvegicus) |
Mammalia | St3gal6 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | ST3GAL6 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
ManyToMany | |
| chicken (Gallus gallus) |
Aves | ST3GAL6 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | ST3GAL6 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | st3gal6 33 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | st3Gal-VI 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | st3gal5l 34 |
|
ManyToMany |
- Species where no ortholog for ST3GAL6 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for ST3GAL6 Gene
Paralogs for ST3GAL6 Gene
(6) SIMAP similar genes for ST3GAL6 Gene using alignment to 11 proteins:
Variants for ST3GAL6 Gene
| SNP ID | Clin | Chr 03 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000049376 | -- | 98,730,772(+) | C/T | upstream_transcript_variant | |
| rs1000067078 | -- | 98,784,633(+) | G/A | intron_variant | |
| rs1000103923 | -- | 98,731,867(+) | C/T | upstream_transcript_variant | |
| rs1000117681 | -- | 98,732,317(+) | G/A | 5_prime_UTR_variant, genic_upstream_transcript_variant, upstream_transcript_variant | |
| rs1000127715 | -- | 98,736,427(+) | C/T | genic_upstream_transcript_variant, intron_variant |
Residual Variation Intolerance Score:
55% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.70;
66.12% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ST3GAL6 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ST3GAL6 Gene
Disorders for ST3GAL6 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| sialuria |
|
|
Search ST3GAL6 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for ST3GAL6
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for ST3GAL6 Gene
Publications for ST3GAL6 Gene
- Molecular cloning of a novel alpha2,3-sialyltransferase (ST3Gal VI) that sialylates type II lactosamine structures on glycoproteins and glycolipids. (PMID: 10206952) Okajima T … Furukawa K (The Journal of biological chemistry 1999) 2 3 4 22 58
- Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes. (PMID: 20532202) Naukkarinen J … ENGAGE Consortium (PLoS genetics 2010) 3 44 58
- IL-6 and IL-8 increase the expression of glycosyltransferases and sulfotransferases involved in the biosynthesis of sialylated and/or sulfated Lewisx epitopes in the human bronchial mucosa. (PMID: 17944600) Groux-Degroote S … Delannoy P (The Biochemical journal 2008) 3 22 58
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
Products for ST3GAL6 Gene
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- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for ST3GAL6
- Novus Biologicals proteins and lysates for ST3GAL6
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for ST3GAL6
- Abcam proteins for ST3GAL6
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- Browse Primary Antibodies
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- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for ST3GAL6
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for ST3GAL6
- VectorBuilder custom plasmid, inducible vectors for ST3GAL6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ST3GAL6
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for ST3GAL6
- antibodies-online: Search results for 16 available ST3GAL6 Antibodies ranked by validation data
- Compare Top ST3GAL6 Antibodies
- antibodies-online: Search results for available ST3GAL6 related products ranked by validation data
- antibodies-online: Search results for 8 available ST3GAL6 Proteins ranked by validation data
- Compare Top ST3GAL6 Proteins
- Search GeneTex for Antibodies for ST3GAL6
- Search GeneTex for Proteins for ST3GAL6
- ViGene Biosciences adenoviral particle packaged cDNA for ST3GAL6 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ST3GAL6 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ST3GAL6 gene
- Search ViGene Biosciences for ST3GAL6
- Browse Santa Cruz Biotechnology (SCBT) Antibodies
- Search Santa Cruz Biotechnology (SCBT) for ST3GAL6 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ST3GAL6
- Custom Antibody ServicesProSci Antibodies for ST3GAL6
- Search for ST3GAL6 Proteins at ProSci
- Horizon Cell Lines for ST3GAL6
- genomics-online: cdna clones - Search results for available ST3GAL6 gene related products
- orf clones - Search results for available ST3GAL6 gene related products
- genomics-online: gRNA clones - Search results for available ST3GAL6 gene related products
- genomics-online: primer clones - Search results for available ST3GAL6 gene related products
- genomics-online: shRNA clones - Search results for available ST3GAL6 gene related products
Sources for ST3GAL6 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew