ST3GAL6 Gene
protein-coding GIFtS : 57 GCID: GC03 P098451
ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 6 sialyltransferase 10 (alpha-2,3-sialyltransferase VI) )SIAT10 )
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Aliasesfor ST3GAL6 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
10 fRNAdb ,
12 H-InvDB ,
13 NCBI ,
14 NONCODE ,
and/or 15 RNAdb )About This Section Aliases ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 6 1 2 EC 2.4.99.-3 SIAT101 2 3 ST3GalVI3 Sialyltransferase 10 (Alpha-2,3-Sialyltransferase VI)1 2 Sialyltransferase 103 CMP-NeuAc:Beta-Galactoside Alpha-2,3-Sialyltransferase VI2 3 ST3Gal VI3 ST3GALVI2 5 EC 2.4.998 Alpha2,3-Sialyltransferase ST3Gal VI2 EC 2.4.99.98 Type 2 Lactosamine Alpha-2,3-Sialyltransferase2
Export aliases for ST3GAL6 gene to outside databases Previous GC identifers: GC03P099935 GC03P095823
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Summariesfor ST3GAL6 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for ST3GAL6 Gene: The protein encoded by this gene is a member of the sialyltransferase family. Members of this family are enzymes that transfer sialic acid from the activated cytidine 5'-monophospho-N-acetylneuraminic acid to terminal positions on sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. This protein has high specificity for neolactotetraosylceramide and neolactohexaosylceramide as glycolipid substrates and may contribute to the formation of selectin ligands and sialyl Lewis X, a carbohydrate important for cell-to-cell recognition and a blood group antigen. Alternative splicing results in multiple transcript variants that encode different protein isoforms. (provided by RefSeq, Sep 2012) GeneCards Summary for ST3GAL6 Gene: ST3GAL6 (ST3 beta-galactoside alpha-2,3-sialyltransferase 6) is a protein-coding gene. Diseases associated with ST3GAL6 include sialuria inflammatory breast carcinoma related super-pathways are Metabolic pathways and Metabolism of carbohydrates . GO annotations related to this gene include beta-galactoside alpha-2,3-sialyltransferase activity . An important paralog of this gene is ST3GAL3 . UniProtKB/Swiss-Prot: SIA10_HUMAN, Q9Y274 Function : Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has aalpha-2,3-sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1
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Genomic Viewsfor ST3GAL6 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 73) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000003.11 NT_005612.16 NC_018914.2 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ST3GAL6 gene promoter:SREBP-1c RelA NF-kappaB GATA-1 SREBP-1b E2F SREBP-1a E2F-1 NF-kappaB1 RSRFC4 Other transcription factors Search SABiosciences Chromatin IP Primers for ST3GAL6 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 3q12.1 Ensembl cytogenetic band: 3q12.1 HGNC cytogenetic band: 3q12.2 ST3GAL6 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 3 GeneLoc Exon Structure
GeneLoc location for GC03P098451: view genomic region
(about GC identifiers )
Start: 98,451,080 bp from pter End:
98,540,045 bp from pter
Size: 88,966 bases Orientation:
plus strand
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Proteinsfor ST3GAL6 gene
(According to
UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE 1 MOPED ,
2 PaxDb , and 3 MAXQB
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Cloud-Clone Corp. ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Cloud-Clone Corp. ,
Ontologies according to Gene
Ontology Consortium 01 Oct 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
LSBio ,
Abcam , and/or
Cloud-Clone Corp. )
About This Section UniProtKB/Swiss-Prot: SIA10_HUMAN, Q9Y274 See
protein sequence )Recommended Name: Size : 331 amino acids; 38214 DaSubcellular location : Golgi apparatus membrane; Single-pass type II membrane protein (Potential)Secondary accessions : B2RCH2 B3KMI1 D3DN39 F8W6U0Alternative splicing : 2 isoforms : Q9Y274-1 Q9Y274-2 Explore the universe of human proteins at neXtProt for ST3GAL6: NX_Q9Y274 Explore proteomics data for ST3GAL6 at MOPED
4/14 DME Specific Peptides for ST3GAL6 (Q9Y274 ) (see all 14 )ST3GAL6 Protein expression data from MOPED1 2 3 : About this image REFSEQ proteins (6 alternative transcripts): NP_001258071.1 NP_001258074.1 NP_001258075.1 NP_001258076.1 NP_001258077.1 NP_006091.1 ENSEMBL proteins: ENSP00000417376 ENSP00000419209 ENSP00000419690 ENSP00000420047 ENSP00000417584 ENSP00000418896 ENSP00000418581 ENSP00000417109 ENSP00000420474 ENSP00000418650 ENSP00000420693 ENSP00000417201 ENSP00000419987 ENSP00000419202 ENSP00000377717 ENSP00000265261 Reactome Protein details: Q9Y274 Human Recombinant Protein Products for ST3GAL6: Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view) : About this table
About GeneDecksing ST3GAL6 Antibody Products: Assay Products for ST3GAL6:
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Protein
Domains /for ST3GAL6 gene (According to HGNC , IUPHAR , InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section HGNC Gene Families: ST3G: Sialyltransferases 2 InterPro protein domains :
Graphical View of Domain Structure for InterPro Entry Q9Y274 ProtoNet protein and cluster: Q9Y274
1 Blocks protein domain : IPB001675 UniProtKB/Swiss-Prot: SIA10_HUMAN, Q9Y274 Similarity : Belongs to the glycosyltransferase 29 familyAbout GeneDecksing
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Functionfor ST3GAL6 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene .)
About This Section Molecular Function: UniProtKB/Swiss-Prot Summary: SIA10_HUMAN, Q9Y274 Function : Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has aalpha-2,3-sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1 Enzyme Numbers (IUBMB): EC 2.4.99.9 2 EC 2.4.99.- 1 EC 2.4.99 2
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0008373 sialyltransferase activity
-- -- GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity
IDA 10206952
About GeneDecksing Phenotypes: 1 GenomeRNAi human phenotype for ST3GAL6 :3 MGI mutant phenotypes (inferred from 1 allele(MGI details for St3gal6) :About GeneDecksing Animal Models: St3gal6 tm1.1Jxm for ST3GAL6In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ST3GAL6
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Pathways & Interactionsfor ST3GAL6 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Sino Biological ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene) .
About This Section SuperPaths for ST3GAL6 About (see all 8 ) See pathways by source SuperPath Selected contained pathways About (see all per SuperPath ) 1 Metabolism 2 MPS IIIC - Sanfilippo syndrome C 3 Keratan sulfate biosynthesis 4 Pre-NOTCH Processing in Golgi 5 Signaling by NOTCH1 t(7 9)(NOTCH1:M1580 K2555) Translocation Mutant
Pathways by source See SuperPaths Show all pathways 5/22 (see all 22 )2 (Kegg details for ST3GAL6) :About GeneDecksing Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ST3GAL6 STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)5/28 Interacting proteins for ST3GAL6 (ENSP00000377717 4 via UniProtKB, MINT, STRING , and/or I2D (see all 28 )About this table Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10 ): About this table
About GeneDecksing
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Drugs & Compoundsfor ST3GAL6 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
IUPHAR ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section About GeneDecksing Browse Tocris compounds for ST3GAL6 (SIA10) 3 HMDB Compounds for ST3GAL6 About this table 3 Novoseek inferred chemical compound relationships for ST3GAL6 gene About this table
Compound
-log (P-Val)
Hits
PubMed IDs for Articles with Shared Sentences (# sentences)
gal(beta1-3)galnac
73.7
1
9628888 (1)
sialic acid
72.5
1
9182658 (1)
asialo gm1
70.2
1
12716912 (1)
ST3GAL6 / SIA10
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Transcriptsfor ST3GAL6 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , KenesGroup ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for ST3GAL6 gene (6 alternative transcripts): NM_001271142.1 NM_001271145.1 NM_001271146.1 NM_001271147.1 NM_001271148.1 NM_006100.3 Unigene Cluster for ST3GAL6:
ST3 beta-galactoside alpha-2,3-sialyltransferase 6 Hs.148716 [show with all ESTs ] Unigene Representative Sequence: CR749468 18/27 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 27 ): ENST00000489112 ENST00000483910 ENST00000460774 ENST00000469105 (uc003dsy.3 uc003dsz.3 uc003dta.3 )ENST00000466482 ENST00000462152 ENST00000486249 ENST00000497008 ENST00000486334 ENST00000480133 ENST00000497621 (uc003dtc.3 uc010hpd.3 ) ENST00000465004 ENST00000476833 ENST00000468553 ENST00000490684 ENST00000485391 ENST00000495376 ENST00000492254 Primer ST3GAL6 human mouse SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat
Additional mRNA sequence: AB022918.1 AF119391.1 AK001922.1 AK315111.1 BC001266.2 BC012092.1 BC023312.1 CR749468.1
22 DOTS entries : DT.91648904 DT.100780429
DT.441821 DT.91723321 DT.75160594 DT.92048988 DT.100654969 DT.100780433 DT.40292564 DT.442867 DT.99999677 DT.100780430 DT.100780431 DT.120914520 DT.40272715 DT.95200021 DT.99999477 DT.120914582 DT.120914610 DT.75110962 DT.91971078 DT.92419998 24/155 AceView cDNA sequences (see all 155 ):
AB022918 AI478510 CA396843 AI056701 BC001266 BM449842 BF589596 AI471207 BF447500 Z43713 AI955457 N91882 CA308014 BC023312 BE465534 BU165940 BX092348 AA884052 NM_006100 CR624848 BE348317 BU188066 AI984377 CR607538 GeneLoc Exon Structure 5/15 Alternative Splicing Database (ASD) splice patterns (SP) for ST3GAL6 (see all 15 ) About this scheme ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ SP1 : - - - - - - - - - - - - SP2 : - - - - - - - - - SP3 : - - - - - - - - - - - - - SP4 : - - - - - - - - - - - - - - SP5 : - - - - - - - - - -
ExUns: 16 ^ 17 ^ 18a · 18b · 18c · 18d · 18e · 18f SP1 : SP2 : SP3 : SP4 : SP5 :
ECgene alternative splicing isoforms for ST3GAL6
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Expression for ST3GAL6 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section ST3GAL6 expression in normal human tissues
(normalized intensities) ST3GAL6 embryonic expression: see See probesets specificity/sensitivity at GeneAnnot About this image BioGPS 2/3 CGAP TAG: ATTGTGAAGAAbout this image
ST3GAL6 expression in embryonic tissues and stem cells About this table LifeMap ,
the Embryonic Development and Stem Cells Database 5/7 selected tissues (see all 7 ) fully expand See ST3GAL6 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ST3GAL6 SOURCE GeneReport for Unigene cluster: Hs.148716 UniProtKB/Swiss-Prot: SIA10_HUMAN, Q9Y274 Tissue specificity : UbiquitousSABiosciences Custom PCR Arrays for ST3GAL6 Primer ST3GAL6 human mouse SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ST3GAL6
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Orthologsfor ST3GAL6 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section Orthologs for ST3GAL6 gene from 4/9 species (see all 9 ) About this table
Organism
Taxonomic
Gene
Description
Human
Orthology
Details
mouse Mammalia St3gal61 5
ST3 beta-galactoside alpha-2,3-sialyltransferase 61, 5
81.46(n) 1 74.47(a) 1
16 (34.58 cM) 5 54613 1 NM_018784.2 1 NP_061254.1 1 58468125 5
chicken Aves ST3GAL61
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
69.1(n) 63.83(a)
395138 NM_204479.1 NP_989810.1
lizard Reptilia ST3GAL66
ST3 beta-galactoside alpha-2,3-sialyltransferase 6... 55(a)
1 ↔ 1
3(174911192-174949257)
African clawed frog Amphibia st3Gal-VI2
alpha2,3-sialyltransferase
72.66(n)
AJ585766.1
ENSEMBL Gene Tree for ST3GAL6 (if available)TreeFam Gene Tree for ST3GAL6 (if available)
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Paralogsfor ST3GAL6 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for ST3GAL6 gene ST3GAL3 2 ST6GALNAC1 2 ST6GALNAC2 2 ST3GAL1 2 ST3GAL4 2 ST3GAL2 2 ST3GAL5 2 6 SIMAP similar genes for ST3GAL6 using alignment to 11 protein entries: SIA10_HUMAN (see all proteins ):ST3GAL1 ST3GAL4 ST3GAL3 SIAT4C ST3GAL5 ST3GalIII About GeneDecksing
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Genomic Variantsfor ST3GAL6 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
4 UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical Chr 3 pos Sequence # AA Type More # Allele Pop Total More
HapMap Linkage Disequilibrium report for ST3GAL6 (98451080 - 98540045 bp)
Structural Variations Database of Genomic Variants (DGV) 2 variations for ST3GAL6 : About this table Human Gene Mutation Database (HGMD) : ST3GAL6 SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human mouse rat
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Disorders
/ Diseasesfor ST3GAL6 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Conferences by KenesGroup ,
Novoseek , Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section About GeneDecksing OMIM gene information: 607156
OMIM disorders : --11 : About MalaCards sialuria inflammatory breast carcinoma morquio syndrome b major depressive disorder obesity neuroblastoma hepatitis b hepatocellular carcinoma endotheliitis hepatitis breast cancer 2 Novoseek inferred disease relationships for ST3GAL6 gene About this table
Disease
-log (P-Val)
Hits
PubMed IDs for Articles with Shared Sentences (# sentences)
breast carcinoma
17.7
1
10561455 (1)
carcinoma
1.99
1
11389097 (1)
Genetic Association Database (GAD): ST3GAL6 Human Genome Epidemiology (HuGE) Navigator: ST3GAL6 (1 document)Export disorders for ST3GAL6 gene to outside databases
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Publicationsfor ST3GAL6 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for ST3GAL6 gene, integrated from 9 sources (see all 49 ):(articles sorted by number of sources associating them with ST3GAL6) Utopia : connect your pdf to the dynamic
Molecular cloning of a novel alpha2,3-sialyltransferase (ST3Gal VI) that sialylates type II lactosamine structures on glycoproteins and glycolipids. (PubMed id 10206952) 1 , 2 , 3, 9(1999) Use of genome-wide expression data to mine the ' Gray Zone' of GWA studies leads to novel candidate obesity genes. (PubMed id 20532202) 1 , 4(2010) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 (2004) IL-6 and IL-8 increase the expression of glycosyltransferases and sulfotransferases involved in the biosynthesis of sialylated and/or sulfated Lewis x epitopes in the human bronchial mucosa. (PubMed id 17944600) 1 , 9(2008) Coordinated roles of ST3Gal-VI and ST3Gal-IV sialyltra nsferases in the synthesis of selectin ligands. (PubMed id 22700726) 1 (2012) A fine-mapping study of 7 top scoring genes from a GWA S for major depressive disorder. (PubMed id 22649524) 1 (2012) Selectin ligand sialyl-Lewis x antigen drives metastas is of hormone-dependent breast cancers. (PubMed id 22025563) 1 (2011) Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049) 1 (2011) Differences in CD75s- and iso-CD75s-ganglioside conte nt and altered mRNA expression of sialyltransferases ST6GAL1 and ST3GAL6 in hum an hepatocellular carcinomas and nontumoral liver tissues. (PubMed id 21147760) 1 (2011)
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Genome Databases showing ST3GAL6 gene
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Specialized Databases showing ST3GAL6 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description PharmGKB entry for ST3GAL6 Pharmacogenomics, SNPs, Pathways GGDB http://riodb.ibase.aist.go.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=ST3GAL6 Functional Glycomics Gateway - GTase http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_627
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About This Section Patent Information for ST3GAL6 gene: ST3GAL6 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor ST3GAL6 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Cloud-Clone Corp. , Thermo Fisher Scientific , LSBio , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ST3GAL6 QIAGEN SeqTarget long-range PCR primers in human mouse rat QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ST3GAL6
ThermoFisher Antibodies for ST3GAL6
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ST3GAL6
LSBio Antibodies in human mouse rat
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