Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



ST3GAL3 Gene

protein-coding   GIFtS: 60
GCID: GC01P044173

ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 3

(Previous names: sialyltransferase 6 (N-acetyllacosaminide alpha 2,3-sialyltransferase),...)
(Previous symbols: SIAT6, MRT12)
  See ST3GAL3-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 31 2     ST3GALII2 5
SIAT61 2 3 5     Alpha 2,3-Sialyltransferase III2
ST3Gal III1 2 3     Alpha-2,3-Sialyltransferase II2
MRT121 2 5     CMP-N-Acetylneuraminate-Beta-1,4-Galactoside Alpha-2,3-Sialyltransferase2
Mental Retardation, Non-Syndromic, Autosomal Recessive, 121 2     Gal Beta-1,3(4)GlcNAc Alpha-2,3 Sialyltransferase2
Sialyltransferase 6 (N-Acetyllacosaminide Alpha 2,3-Sialyltransferase)1 2     EC 2.4.99.63
Alpha 2,3-ST 32 3     Beta-Galactoside Alpha-2,3-Sialyltransferase 33
ST3GalIII2 3     Gal Beta-1,3(4) GlcNAc Alpha-2,3 Sialyltransferase3
ST3N2 3     N-Acetyllactosaminide Alpha-2,3-Sialyltransferase3
EIEE152 5     Sialyltransferase 63

External Ids:    HGNC: 108661   Entrez Gene: 64872   Ensembl: ENSG000001260917   OMIM: 6064945   UniProtKB: Q112033   

Export aliases for ST3GAL3 gene to outside databases

Previous GC identifers: GC01P043844 GC01P043946 GC01P042293


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for ST3GAL3 Gene:
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from
CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi apparatus
but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family
29. Mutations in this gene have been associated with autosomal recessive nonsymdromic mental retardation-12
(MRT12). Multiple transcript variants encoding several different isoforms have been found for this gene.
(provided by RefSeq, Jul 2012)

GeneCards Summary for ST3GAL3 Gene:
ST3GAL3 (ST3 beta-galactoside alpha-2,3-sialyltransferase 3) is a protein-coding gene. Diseases associated with ST3GAL3 include ohtahara syndrome, and epileptic encephalopathy, early infantile, 5. GO annotations related to this gene include N-acetyllactosaminide alpha-2,3-sialyltransferase activity and beta-galactoside (CMP) alpha-2,3-sialyltransferase activity. An important paralog of this gene is ST6GALNAC1.

UniProtKB/Swiss-Prot: SIAT6_HUMAN, Q11203
Function: Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc-,
NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- or NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- sequences found in terminal
carbohydrate groups of glycoproteins and glycolipids. The highest activity is toward Gal-beta-1,3-GlcNAc and the
lowest toward Gal-beta-1,3-GalNAc (By similarity)

Gene Wiki entry for ST3GAL3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_032977.10  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ST3GAL3 gene promoter:
         TBP   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidST3GAL3 promoter sequence
   Search Chromatin IP Primers for ST3GAL3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ST3GAL3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p34.1   Ensembl cytogenetic band:  1p34.1   HGNC cytogenetic band: 1p34.1

ST3GAL3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ST3GAL3 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P044173:  view genomic region     (about GC identifiers)

Start:
44,171,495 bp from pter      End:
44,396,831 bp from pter
Size:
225,337 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: SIAT6_HUMAN, Q11203 (See protein sequence)
Recommended Name: CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase  
Size: 375 amino acids; 42171 Da
Secondary accessions: A9Z1W2 D3DPX8 Q5T4W9 Q5T4X0 Q5T4X7 Q5T4X8 Q5T4X9 Q5T4Y0 Q5T4Y2 Q5T4Y3
Q5T4Y4 Q86UR6 Q86UR7 Q86UR8 Q86UR9 Q86US0 Q86US1 Q86US2 Q8IX41 Q8IX42 Q8IX43 Q8IX44 Q8IX45
Q8IX46 Q8IX47 Q8IX48 Q8IX49 Q8IX50 Q8IX51 Q8IX52 Q8IX53 Q8IX54 Q8IX55 Q8IX56 Q8IX57 Q8IX58
Alternative splicing: 26 isoforms:  Q11203-1   Q11203-2   Q11203-3   Q11203-4   Q11203-5   Q11203-6   Q11203-7   Q11203-8   
Q11203-9   Q11203-10   Q11203-11   Q11203-12   Q11203-13   Q11203-14   Q11203-15   Q11203-16   
Q11203-17   Q11203-18   Q11203-19   Q11203-20   Q11203-21   Q11203-22   Q11203-23   Q11203-24   
Q11203-25   Q11203-26   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for ST3GAL3: NX_Q11203

Explore proteomics data for ST3GAL3 at MOPED

Post-translational modifications: 

  • The soluble form derives from the membrane form by proteolytic processing1
  • Glycosylation2 at Asn80, Asn171
  • Modification sites at PhosphoSitePlus

  • See ST3GAL3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (18 alternative transcripts): 
    NP_001257388.1  NP_001257389.1  NP_001257390.1  NP_001257391.1  NP_001257392.1  NP_001257393.1  NP_001257394.1  NP_001257395.1  
    NP_006270.1  NP_777623.2  NP_777624.1  NP_777625.1  NP_777626.1  NP_777627.1  NP_777628.2  NP_777629.1  
    NP_777630.1  NP_777631.2  

    ENSEMBL proteins: 
     ENSP00000431816   ENSP00000437206   ENSP00000434686   ENSP00000355341   ENSP00000354748  
     ENSP00000432214   ENSP00000317192   ENSP00000433668   ENSP00000355201   ENSP00000361437  
     ENSP00000435603   ENSP00000361444   ENSP00000354657   ENSP00000361442   ENSP00000361441  
     ENSP00000361440   ENSP00000361443   ENSP00000361447   ENSP00000435018   ENSP00000431700  
     ENSP00000434876   ENSP00000432682   ENSP00000432965   ENSP00000435621   ENSP00000432071  
     ENSP00000437293   ENSP00000329755   ENSP00000434378   ENSP00000436298   ENSP00000262915  
     ENSP00000361450   ENSP00000316999   ENSP00000361449   ENSP00000330463   ENSP00000439634  
     ENSP00000333494   ENSP00000335633   ENSP00000361452  
    Reactome Protein details: Q11203

    ST3GAL3 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for ST3GAL3
    OriGene Custom MassSpec
    OriGene Custom Protein Services for ST3GAL3
    GenScript Custom Purified and Recombinant Proteins Services for ST3GAL3
    Novus Biologicals ST3GAL3 Proteins
    Novus Biologicals ST3GAL3 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for ST3GAL3 

    ST3GAL3 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ST3GAL3
    Novus Biologicals ST3GAL3 Antibodies
    Abcam antibodies for ST3GAL3
    Browse Antibodies at Cloud-Clone Corp.
    ThermoFisher Antibody for ST3GAL3
    LSBio Antibodies in human, mouse, rat for ST3GAL3

    ST3GAL3 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ST3GAL3
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ST3GAL3
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for ST3GAL3 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    ST3G: Sialyltransferases

    2 InterPro protein domains:
     IPR001675 Glyco_trans_29
     IPR012163 Sialyl_trans

    Graphical View of Domain Structure for InterPro Entry Q11203

    ProtoNet protein and cluster: Q11203

    1 Blocks protein domain: IPB001675 Glycosyl transferase

    UniProtKB/Swiss-Prot: SIAT6_HUMAN, Q11203
    Similarity: Belongs to the glycosyltransferase 29 family


    Find genes that share domains with ST3GAL3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SIAT6_HUMAN, Q11203
    Function: Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc-,
    NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- or NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- sequences found in terminal
    carbohydrate groups of glycoproteins and glycolipids. The highest activity is toward Gal-beta-1,3-GlcNAc and the
    lowest toward Gal-beta-1,3-GalNAc (By similarity)
    Catalytic activity: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-glycoprotein = CMP
    + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-glycoprotein

         Enzyme Number (IUBMB): EC 2.4.99.61

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003836beta-galactoside (CMP) alpha-2,3-sialyltransferase activity IEA--
    GO:0008118N-acetyllactosaminide alpha-2,3-sialyltransferase activity IEA--
    GO:0008373sialyltransferase activity ----
         
    Find genes that share ontologies with ST3GAL3           About GenesLikeMe


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for St3gal3):
     hematopoietic system 

    Find genes that share phenotypes with ST3GAL3           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out St3gal3tm1Jxm for ST3GAL3

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ST3GAL3
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ST3GAL3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ST3GAL3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ST3GAL3

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat ST3GAL3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ST3GAL3 (see all 42):
    hsa-miR-328 hsa-miR-188-5p hsa-miR-330-5p hsa-miR-200a hsa-miR-1260b hsa-miR-3921 hsa-miR-374c hsa-miR-141
    SwitchGear 3'UTR luciferase reporter plasmidST3GAL3 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ST3GAL3
    Predesigned siRNA for gene silencing in human, mouse, rat ST3GAL3

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ST3GAL3

    Clone
    Products:
         
    OriGene clones in human, mouse for ST3GAL3 (see all 55)
    OriGene ORF clones in mouse, rat for ST3GAL3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 10): ST3GAL3 (NM_006279)
    Sino Biological Human cDNA Clone for ST3GAL3
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ST3GAL3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ST3GAL3

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ST3GAL3
    Browse ESI BIO Cell Lines and PureStem Progenitors for ST3GAL3 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ST3GAL3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    SIAT6_HUMAN, Q11203: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted.
    Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    golgi apparatus5
    lysosome1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane TAS--
    GO:0005576extracellular region IEA--
    GO:0030173integral component of Golgi membrane IEA--
    GO:0032580Golgi cisterna membrane IEA--

    Find genes that share ontologies with ST3GAL3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for ST3GAL3 About   (see all 11)  
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Keratan sulfate/keratin metabolism
    Keratan sulfate/keratin metabolism0.85
    Glycosaminoglycan biosynthesis - keratan sulfate0.43
    Keratan sulfate biosynthesis0.85
    2Metabolism
    Metabolism0.38
    Metabolic pathways0.38
    3MPS VI - Maroteaux-Lamy syndrome
    MPS VI - Maroteaux-Lamy syndrome0.45
    MPS IIIB - Sanfilippo syndrome B0.45
    MPS IIIC - Sanfilippo syndrome C0.45
    MPS II - Hunter syndrome0.45
    MPS IV - Morquio syndrome A0.45
    Glycosaminoglycan metabolism0.45
    Mucopolysaccharidoses0.45
    MPS IV - Morquio syndrome B0.45
    4Pre-NOTCH Expression and Processing
    Pre-NOTCH Expression and Processing0.62
    Pre-NOTCH Processing in Golgi0.00
    5O-linked glycosylation of mucins
    O-linked glycosylation of mucins0.47
    Termination of O-glycan biosynthesis0.38


    Find genes that share SuperPaths with ST3GAL3           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    4 Reactome Pathways for ST3GAL3
        Pre-NOTCH Processing in Golgi
    Sialic acid metabolism
    Keratan sulfate biosynthesis
    Termination of O-glycan biosynthesis


    4 Kegg Pathways  (Kegg details for ST3GAL3):
        Other types of O-glycan biosynthesis
    Glycosaminoglycan biosynthesis - keratan sulfate
    Glycosphingolipid biosynthesis - lacto and neolacto series
    Metabolic pathways

    UniProtKB/Swiss-Prot: SIAT6_HUMAN, Q11203
    Pathway: Protein modification; protein glycosylation

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ST3GAL3
    Interactions:

        Search GeneGlobe Interaction Network for ST3GAL3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ST3GAL3 (Q112032, 3 ENSP000002629154) via UniProtKB, MINT, STRING, and/or I2D (see all 41)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPL8P629172, 3MINT-64082 I2D: score=4 
    ZBTB5O150622, 3MINT-64080 I2D: score=4 
    ACTG1P632612, 3MINT-64083 I2D: score=3 
    TTRP027662, 3MINT-64081 I2D: score=3 
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process TAS--
    GO:0006486protein glycosylation ----
    GO:0016266O-glycan processing TAS--
    GO:0018146keratan sulfate biosynthetic process TAS--
    GO:0030203glycosaminoglycan metabolic process TAS--

    Find genes that share ontologies with ST3GAL3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ST3GAL3 (SIAT6)

    2 HMDB Compounds for ST3GAL3    About this table
    CompoundSynonyms CAS #PubMed Ids
    Cytidine monophosphate5'-CMP (see all 14)63-37-6--
    Cytidine monophosphate N-acetylneuraminic acidCMP-N-acetylneuraminate (see all 6)22-12-8--

    3 Novoseek inferred chemical compound relationships for ST3GAL3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    sialic acid 71.9 2 19418726 (1), 8611500 (1)
    galactose 36.8 1 9838208 (1)
    polysaccharide 31.5 3 1417784 (2), 7737417 (1)



    Find genes that share compounds with ST3GAL3           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for ST3GAL3 gene (19 alternative transcripts): 
    NM_001270459.1  NM_001270460.1  NM_001270461.1  NM_001270462.1  NM_001270463.1  NM_001270464.1  NM_001270465.1  NM_001270466.1  
    NM_006279.3  NM_174963.3  NM_174964.2  NM_174965.2  NM_174966.2  NM_174967.2  NM_174968.3  NM_174969.2  
    NM_174970.2  NM_174971.3  NM_174972.1  

    Unigene Cluster for ST3GAL3:

    ST3 beta-galactoside alpha-2,3-sialyltransferase 3
    Hs.597915  [show with all ESTs]
    Unigene Representative Sequence: NM_174963
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 41):
    ENST00000532911(uc009vwu.1) ENST00000489897 ENST00000530154(uc010okj.1)
    ENST00000361392(uc001ckc.3 uc001ckg.3 uc001cki.3 uc009vwv.3 uc001ckj.3 uc001ckk.3 uc001ckl.3 uc009vwx.3 uc009vwz.3 uc001ckn.3)
    ENST00000361400(uc001cka.3 uc001cke.3 uc009vww.3 uc009vwy.3 uc001cko.3 uc009vxa.3 uc001ckq.3 uc001ckr.3 uc009vxb.3)
    ENST00000479383 ENST00000347631 ENST00000484868 ENST00000461066 ENST00000361812
    ENST00000372362 ENST00000531451 ENST00000372369 ENST00000361746 ENST00000372367
    ENST00000372366 ENST00000372365 ENST00000372368
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ST3GAL3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ST3GAL3 (see all 42):
    hsa-miR-328 hsa-miR-188-5p hsa-miR-330-5p hsa-miR-200a hsa-miR-1260b hsa-miR-3921 hsa-miR-374c hsa-miR-141
    SwitchGear 3'UTR luciferase reporter plasmidST3GAL3 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ST3GAL3
    Predesigned siRNA for gene silencing in human, mouse, rat ST3GAL3
    Clone
    Products:
         
    OriGene clones in human, mouse for ST3GAL3 (see all 55)
    OriGene ORF clones in mouse, rat for ST3GAL3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 10): ST3GAL3 (NM_006279)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ST3GAL3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ST3GAL3
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ST3GAL3
    OriGene qSTAR qPCR primer pairs in human, mouse for ST3GAL3
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ST3GAL3
      QuantiTect SYBR Green Assays in human, mouse, rat ST3GAL3
      QuantiFast Probe-based Assays in human, mouse, rat ST3GAL3

    Additional mRNA sequence: 

    AK301829.1 AK310265.1 AY051143.1 AY167993.1 AY167994.1 AY167995.1 AY167997.1 AY167998.1 
    BC050380.1 L23768.1 NR_073016.1 NR_073017.1 NR_073018.1 NR_073019.1 NR_073020.1 NR_073021.1 
    NR_073023.1 

    18 DOTS entries:

    DT.97781971  DT.100025325  DT.100883676  DT.92427640  DT.100883683  DT.100883687  DT.95173416  DT.113751 
    DT.100883674  DT.100883686  DT.75189663  DT.100883681  DT.75115324  DT.97813188  DT.100883672  DT.95173418 
    DT.91719015  DT.92427643 

    Selected AceView cDNA sequences (see all 185):

    AL157645 AF425860 AF425853 AY167995 AF425852 NM_174972 AF425866 AF425865 
    BQ653434 AF425851 AW138977 AF425859 BQ050567 NM_174964 AF425858 AY167993 
    AF425857 NM_174969 CR613052 BG761784 AF425862 AF425864 AI494439 NM_174965 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ST3GAL3 (see all 27)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b · 3c · 3d ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16a · 16b ^
    SP1:                                            -           -     -     -     -           -     -     -                 -     -                                 
    SP2:                                            -           -     -     -     -                       -                 -     -                                 
    SP3:                                                        -     -     -     -                       -                 -     -                                 
    SP4:                                            -     -     -     -     -     -                       -                 -     -                                 
    SP5:                                            -           -     -     -     -           -     -     -                 -     -                                 

    ExUns: 17a · 17b ^ 18 ^ 19 ^ 20 ^ 21a · 21b · 21c ^ 22 ^ 23a · 23b · 23c
    SP1:  -           -     -     -     -                                       
    SP2:  -           -     -     -     -                                       
    SP3:  -           -     -     -     -                                       
    SP4:  -           -     -     -     -                                       
    SP5:              -     -     -     -                                       


    ECgene alternative splicing isoforms for ST3GAL3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    ST3GAL3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAAGCAATAA
    ST3GAL3 Expression
    About this image


    ST3GAL3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Cerebral Cortex
     
     Bone (Muscoskeletal System)
             Membranous Facial Bones
     
     Neural Tube (Nervous System)
             Telencephalon
    ST3GAL3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ST3GAL3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.597915

    UniProtKB/Swiss-Prot: SIAT6_HUMAN, Q11203
    Tissue specificity: Highly expressed in adult skeletal muscle and in all fetal tissues examined and to a much
    lesser extent in placenta, lung and liver

        Custom PCR Arrays for ST3GAL3
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for ST3GAL3
    OriGene qSTAR qPCR primer pairs in human, mouse for ST3GAL3
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ST3GAL3
    QuantiTect SYBR Green Assays in human, mouse, rat ST3GAL3
    QuantiFast Probe-based Assays in human, mouse, rat ST3GAL3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ST3GAL3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for ST3GAL3 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia St3gal31 , 5 ST3 beta-galactoside alpha-2,3-sialyltransferase 31, 5 91.8(n)1
    96.52(a)1
      4 (53.84 cM)5
    204411  NM_001285520.11  NP_001272449.11 
     1179321545 
    chicken
    (Gallus gallus)
    Aves ST3GAL31 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 77.52(n)
    87.95(a)
      424572  XM_001233559.3  XP_001233560.1 
    lizard
    (Anolis carolinensis)
    Reptilia ST3GAL36
    ST3 beta-galactoside alpha-2,3-sialyltransferase 3...
    89(a)
    1 ↔ 1
    4(108456646-108753175)
    African clawed frog
    (Xenopus laevis)
    Amphibia st3Gal-III2 alpha2,3-sialyltransferase 76.98(n)    AJ585764.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc639782 hypothetical protein MGC63978 72.97(n)   393326  BC053179.1 


    ENSEMBL Gene Tree for ST3GAL3 (if available)
    TreeFam Gene Tree for ST3GAL3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for ST3GAL3 gene
    ST6GALNAC12  ST3GAL62  ST6GALNAC22  ST3GAL12  ST3GAL42  ST3GAL22  ST3GAL52  
    5 SIMAP similar genes for ST3GAL3 using alignment to 6 protein entries:     SIAT6_HUMAN (see all proteins):
    ST3GalIII    ST3GAL5    ST3GAL6    SIAT4C    ST3GAL4

    Find genes that share paralogs with ST3GAL3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for ST3GAL3 (see all 4418)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0693194
    Epileptic encephalopathy, early infantile, 15 (EIEE15)4--see VAR_0693192 A P mis40--------
    VAR_0665954
    Mental retardation, autosomal recessive 12 (MRT12)4--see VAR_0665952 D Y mis40--------
    VAR_0665944
    Mental retardation, autosomal recessive 12 (MRT12)4--see VAR_0665942 A D mis40--------
    rs1116927991,2
    C,F--44180088(+) ACCCCG/ATCTCT 25 -- int11Minor allele frequency- A:0.50WA 2
    rs46602581,2
    A--44180102(+) aaaatA/Ccaaaa 25 -- int10--------
    rs114202761,2
    C--44184192(+) TTTTT-/TATTTT 25 -- int10--------
    rs3701419281,2
    C--44185335(+) GTCTC-/AAAAAA 25 -- int10--------
    rs580978501,2
    C--44189311(+) AGTCT-/TCACTC 25 -- int10--------
    rs1132200151,2
    C--44194012(+) CTCAG-/AAAACA/A
    AAACAAAAACA
    AAAAC
    43 -- cds1 int11CSA 2
    rs719141321,2
    C--44194761(+) TTTTC-/TTTTTT 25 -- int10--------

    HapMap Linkage Disequilibrium report for ST3GAL3 (44171495 - 44396831 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for ST3GAL3 (see all 18):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1735166CNV Deletion17803354
    esv2747630CNV Deletion23290073
    esv2678921CNV Deletion23128226
    esv2747674CNV Deletion23290073
    esv2674865CNV Deletion23128226
    esv1721659CNV Deletion17803354
    esv2747652CNV Deletion23290073
    esv2747641CNV Deletion23290073
    dgv30e201CNV Deletion23290073
    esv2747663CNV Deletion23290073

    Human Gene Mutation Database (HGMD): ST3GAL3
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ST3GAL3
    DNA2.0 Custom Variant and Variant Library Synthesis for ST3GAL3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 606494   
    OMIM disorders: 611090  615006  
    UniProtKB/Swiss-Prot: SIAT6_HUMAN, Q11203
  • Mental retardation, autosomal recessive 12 (MRT12) [MIM:611090]: A disorder characterized by
    significantly below average general intellectual functioning associated with impairments in adaptive behavior and
    manifested during the developmental period. Note=The disease is caused by mutations affecting the gene
    represented in this entry
  • Epileptic encephalopathy, early infantile, 15 (EIEE15) [MIM:615006]: A form of epilepsy that manifests in
    the neonatal or the early infantile period as severely impaired cognitive and motor development, due to recurrent
    clinical seizures or prominent interictal epileptiform discharges. Patients develop infantile spasms, mainly of
    the flexor type, between 3 and 7 months of age, which are accompanied by hypsarrhythmia on EEG. Other features
    include poor eye contact, hypotonia, primitive reflexes, and irritability. Seizures evolve clinically to
    Lennox-Gastaut syndrome. Note=The disease is caused by mutations affecting the gene represented in this entry

  • 5 diseases for ST3GAL3:    
    About MalaCards
    ohtahara syndrome    epileptic encephalopathy, early infantile, 5    mental retardation, autosomal recessive 43    west syndrome
    mental retardation


    Find genes that share disorders with ST3GAL3           About GenesLikeMe

    4 Novoseek inferred disease relationships for ST3GAL3 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    gastric cancer 11.2 2 12931020 (2)
    carcinoma 0.853 2 11389097 (1), 10673297 (1)
    tumors 0 5 12931020 (2)
    cancer 0 2 15231659 (1)

    Genetic Association Database (GAD): ST3GAL3
    Human Genome Epidemiology (HuGE) Navigator: ST3GAL3 (1 document)

    Export disorders for ST3GAL3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for ST3GAL3 gene, integrated from 10 sources (see all 58):
    (articles sorted by number of sources associating them with ST3GAL3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. ST3GAL3 mutations impair the development of higher cognitive functions. (PubMed id 21907012)1, 2, 3 Hu H....Kuss A.W. (Am. J. Hum. Genet. 2011)
    2. Cloning and expression of human Gal beta 1,3(4)GlcNAc alpha 2,3- sialyltransferase. (PubMed id 8333853)1, 2, 3 Kitagawa H. and Paulson J.C. (Biochem. Biophys. Res. Commun. 1993)
    3. West syndrome caused by ST3Gal-III deficiency. (PubMed id 23252400)1, 2 Edvardson S.... Elpeleg O. (Epilepsia 2013)
    4. A genome-wide association study of aging. (PubMed id 21782286)1, 4 Walter S....Franceschini N. (Neurobiol. Aging 2011)
    5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Clinical relevance of sialyltransferases ST6GAL-I and ST3GAL-III in gastric cancer. (PubMed id 12931020)1, 9 Gretschel S....Kemmner W. (Oncology 2003)
    8. Differential expression of alpha-2,3-sialyltransferases and alpha-1,3/4-fucosyltransferases regulates the levels of sialyl Lewis a and sialyl Lewis x in gastrointestinal carcinoma cells. (PubMed id 19781661)1, 9 Carvalho A.S....Reis C.A. (amp 2010)
    9. Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1. (PubMed id 22959728)1  ....Zheng J.G. (Neurobiol. Aging 2013)
    10. Localization of Golgi-resident glycosyltransferases. (PubMed id 19727557)1 Tu L. and Banfield D.K. (Cell. Mol. Life Sci. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 6487 HGNC: 10866 AceView: SIAT6 Ensembl:ENSG00000126091 euGenes: HUgn6487
    ECgene: ST3GAL3 Kegg: 6487 H-InvDB: ST3GAL3

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for ST3GAL3 Pharmacogenomics, SNPs, Pathways
    GGDBhttp://jcggdb.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=ST3GAL3
    Functional Glycomics Gateway - GTasehttp://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_624

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for ST3GAL3 gene:
    Search GeneIP for patents involving ST3GAL3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ST3GAL3  
     OriGene qPCR primer pairs and template standards for ST3GAL3   OriGene Protein Over-expression Lysate for ST3GAL3  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for ST3GAL3  
     OriGene qSTAR qPCR primer pairs in human, mouse for ST3GAL3   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for ST3GAL3   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ST3GAL3   OriGene Custom Protein Services for ST3GAL3  

     
     
     Block miRNA regulation of human, mouse, rat ST3GAL3 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing ST3GAL3
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ST3GAL3 Predesigned siRNA for gene silencing in human, mouse, rat ST3GAL3
     QuantiFast Probe-based Assays in human, mouse, rat ST3GAL3 QuantiTect SYBR Green Assays in human, mouse, rat ST3GAL3
     Custom PCR Arrays for ST3GAL3 Search Chromatin IP Primers for ST3GAL3
     Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ST3GAL3  Search GeneGlobe Interaction Network for ST3GAL3
     Regulatory tfbs in ST3GAL3 promoter
     GenScript Custom Purified and Recombinant Proteins Services for ST3GAL3 GenScript cDNA clones with any tag delivered in your preferred vector for ST3GAL3
     GenScript Custom Assay Services for ST3GAL3 GenScript Custom overexpressing Cell Line Services for ST3GAL3
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for ST3GAL3 (SIAT6)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for ST3GAL3
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     ST3GAL3 antibodies
     ST3GAL3 proteins
     ST3GAL3 lysates
     Antibodies for ST3GAL3
     See all of Abcam's Antibodies, Kits and Proteins for ST3GAL3
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for ST3GAL3
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ST3GAL3
     SwitchGear 3'UTR luciferase reporter plasmids for ST3GAL3
     SwitchGear Promoter luciferase reporter plasmids for ST3GAL3
     ThermoFisher Antibody for ST3GAL3
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ST3GAL3
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ST3GAL3
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ST3GAL3
     LSBio Antibodies in human, mouse, rat for ST3GAL3
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for ST3GAL3
      Search eBioscience for proteins for ST3GAL3
      Search eBioscience for elisas for ST3GAL3
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ST3GAL3 gene at Home site.
    Version: 3.12.224 13 Oct 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4