Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ST3GAL1 Gene

protein-coding   GIFtS: 61
GCID: GC08M134468

ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 1

(Previous name: sialyltransferase 4A (beta-galactosidase alpha-2,3-sialytransferase))
(Previous symbol: SIAT4A)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 11 2     ST3O2 3
SIAT4A1 2 3     EC 2.4.99.43 8
Sialyltransferase 4A (Beta-Galactosidase Alpha-2,3-Sialytransferase)1 2     ST3GalA2
ST3Gal I1 3     ST3GalIA2
Alpha 2,3-ST 12 3     ST3GalIA,12
Beta-Galactoside Alpha-2,3-Sialyltransferase 12 3     CMP-N-Acetylneuraminate-Beta-Galactosamide-Alpha-2,3-Sialyltransferase 12
Gal-NAc6S2 3     Sialyltransferase 4A (Beta-Galactoside Alpha-2,3-Sialyltransferase)2
Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase2 3     Sialyltransferase 4A (Beta-Galactoside Alpha-2,3-Sialytransferase)2
SIAT4-A2 3     SIAT43
SIATFL2 3     Sialyltransferase 4A3
ST3GalA.12 3     EC 2.4.998
ST3GalI2 3     

External Ids:    HGNC: 108621   Entrez Gene: 64822   Ensembl: ENSG000000085137   OMIM: 6071875   UniProtKB: Q112013   

Export aliases for ST3GAL1 gene to outside databases

Previous GC identifers: GC08M134541 GC08M129786


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ST3GAL1 Gene:
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from
CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be
proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its
sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same
acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been
found for this gene. Other transcript variants may exist, but have not been fully characterized yet. (provided by
RefSeq, Jul 2008)

GeneCards Summary for ST3GAL1 Gene: 
ST3GAL1 (ST3 beta-galactoside alpha-2,3-sialyltransferase 1) is a protein-coding gene. Diseases associated with ST3GAL1 include morquio syndrome b, and graves' disease, and among its related super-pathways are Keratan sulfate/keratin metabolism and Mucin type O-Glycan biosynthesis. GO annotations related to this gene include beta-galactoside (CMP) alpha-2,3-sialyltransferase activity. An important paralog of this gene is ST3GAL3.

UniProtKB/Swiss-Prot: SIA4A_HUMAN, Q11201
Function: It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found on
sugar chains O-linked to Thr or Ser and also as a terminal sequence on certain gangliosides. SIAT4A and SIAT4B
sialylate the same acceptor substrates but exhibit different Km values




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NT_008046.16  NC_018919.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ST3GAL1 gene promoter:
         TBP   Spz1   FAC1   Pax-4a   NF-kappaB1   NF-kappaB   c-Ets-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidST3GAL1 promoter sequence
   Search SABiosciences Chromatin IP Primers for ST3GAL1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ST3GAL1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q24.22   Ensembl cytogenetic band:  8q24.22   HGNC cytogenetic band: 8q24.22

ST3GAL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ST3GAL1 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M134468:  view genomic region     (about GC identifiers)

Start:
134,467,091 bp from pter      End:
134,584,183 bp from pter
Size:
117,093 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SIA4A_HUMAN, Q11201 (See protein sequence)
Recommended Name: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1  
Size: 340 amino acids; 39075 Da
Subcellular location: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted.
Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid
Secondary accessions: O60677 Q9UN51

Explore the universe of human proteins at neXtProt for ST3GAL1: NX_Q11201

Explore proteomics data for ST3GAL1 at MOPED 

Post-translational modifications:

  • UniProtKB: The soluble form derives from the membrane form by proteolytic processing
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q11201

  • 4/9 DME Specific Peptides for ST3GAL1 (Q11201) (see all 9)
     YGFGADS  GFEADVG  HGRYPSTG  WHHYWENN 

    ST3GAL1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ST3GAL1 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_003024.1  NP_775479.1  

    ENSEMBL proteins: 
     ENSP00000428540   ENSP00000430515   ENSP00000429638   ENSP00000427720   ENSP00000429936  
     ENSP00000430135   ENSP00000427786   ENSP00000318445   ENSP00000414073  
    Reactome Protein details: Q11201
    Human Recombinant Protein Products for ST3GAL1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    R&D Systems Recombinant & Natural Proteins for ST3GAL1 (ST3 beta-Gal alpha-2,3-Sialyltransferase 1/ST3GAL1)
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for ST3GAL1
    OriGene Protein Over-expression Lysate for ST3GAL1
    OriGene MassSpec for ST3GAL1 
    OriGene Custom Protein Services for ST3GAL1
    GenScript Custom Purified and Recombinant Proteins Services for ST3GAL1
    Novus Biologicals ST3GAL1 Proteins
    Novus Biologicals ST3GAL1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane TAS--
    GO:0005576extracellular region IEA--
    GO:0005794Golgi apparatus ----
    GO:0016021integral to membrane ----
    GO:0030173integral to Golgi membrane IEA--

    ST3GAL1 for ontologies           About GeneDecksing



    ST3GAL1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for ST3GAL1
    OriGene Custom Antibody Services for ST3GAL1
    GenScript Custom Superior Antibodies Services for ST3GAL1
    Novus Biologicals ST3GAL1 Antibodies
    Abcam antibodies for ST3GAL1
    Browse Antibodies at Cloud-Clone Corp. 
    ThermoFisher Antibodies for ST3GAL1
    LSBio Antibodies in human, mouse, rat for ST3GAL1 

    Assay Products for ST3GAL1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ST3GAL1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ST3GAL1
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp. 
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ST3G: Sialyltransferases

    2 InterPro protein domains:
     IPR001675 Glyco_trans_29
     IPR012163 Sialyl_trans

    Graphical View of Domain Structure for InterPro Entry Q11201

    ProtoNet protein and cluster: Q11201

    1 Blocks protein domain: IPB001675 Glycosyl transferase

    UniProtKB/Swiss-Prot: SIA4A_HUMAN, Q11201
    Similarity: Belongs to the glycosyltransferase 29 family


    ST3GAL1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SIA4A_HUMAN, Q11201
    Function: It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found on
    sugar chains O-linked to Thr or Ser and also as a terminal sequence on certain gangliosides. SIAT4A and SIAT4B
    sialylate the same acceptor substrates but exhibit different Km values
    Catalytic activity: CMP-N-acetylneuraminate + beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R = CMP +
    alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R

         Enzyme Numbers (IUBMB): EC 2.4.99.41 2 EC 2.4.992

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003836beta-galactoside (CMP) alpha-2,3-sialyltransferase activity IEA--
    GO:0008373sialyltransferase activity ----
         
    ST3GAL1 for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for ST3GAL1:
     Downregulation of NF-kappaB pa  Downregulation of NF-kappaB pa  G0/1 arrest  Increased G1 DNA content 

         4 MGI mutant phenotypes (inferred from 2 alleles(MGI details for St3gal1):
     hematopoietic system  immune system  normal  other 

    ST3GAL1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out St3gal1tm1Jxm for ST3GAL1

       inGenious Targeting Laboratory - Custom generated mouse model solutions for ST3GAL1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ST3GAL1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ST3GAL1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ST3GAL1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ST3GAL1
    8/56 QIAGEN miScript miRNA Assays for microRNAs that regulate ST3GAL1 (see all 56):
    hsa-miR-21* hsa-miR-3678-3p hsa-miR-140-5p hsa-miR-520e hsa-miR-302d hsa-let-7d hsa-miR-106a hsa-miR-223
    SwitchGear 3'UTR luciferase reporter plasmidST3GAL1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ST3GAL1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ST3GAL1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ST3GAL1
    Sirion Biotech Customized adenovirus for overexpression of ST3GAL1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for ST3GAL1 (see all 14)
    OriGene ORF clones in mouse, rat for ST3GAL1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): ST3GAL1 (NM_003033)
    Sino Biological Human cDNA Clone for ST3GAL1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ST3GAL1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ST3GAL1
    Sirion Biotech Customized lentivirus for stable overexpression of ST3GAL1 
                         Customized lentivirus expression plasmids for stable overexpression of ST3GAL1 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ST3GAL1
    Search LifeMap BioReagents cell lines for ST3GAL1
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ST3GAL1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for ST3GAL1 About   (see all 8)                                                                                              See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Keratan sulfate biosynthesis
    Keratan sulfate biosynthesis0.82
    Glycosaminoglycan biosynthesis - keratan sulfate0.43
    Keratan sulfate/keratin metabolism0.82
    2O-linked glycosylation of mucins
    O-linked glycosylation of mucins0.44
    Termination of O-glycan biosynthesis0.41
    Mucin type O-Glycan biosynthesis0.44
    3Ganglio Sphingolipid Metabolism
    Ganglio Sphingolipid Metabolism0.53
    Glycosphingolipid biosynthesis - ganglio series0.53
    4Metabolism
    Metabolism0.40
    Metabolic pathways0.40
    5MPS IIIC - Sanfilippo syndrome C
    MPS IIIC - Sanfilippo syndrome C0.48
    Glycosaminoglycan metabolism0.48
    MPS IV - Morquio syndrome A0.48
    MPS IIID - Sanfilippo syndrome D0.48
    MPS VI - Maroteaux-Lamy syndrome0.48
    MPS I - Hurler syndrome0.48
    MPS IV - Morquio syndrome B0.48
    MPS IX - Natowicz syndrome0.48

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for ST3GAL1
        Ganglio Sphingolipid Metabolism


    5/22        Reactome Pathways for ST3GAL1 (see all 22)
        MPS VI - Maroteaux-Lamy syndrome
    Metabolism
    Disease
    Keratan sulfate/keratin metabolism
    MPS II - Hunter syndrome


    5         Kegg Pathways  (Kegg details for ST3GAL1):
        Mucin type O-Glycan biosynthesis
    Glycosaminoglycan biosynthesis - keratan sulfate
    Glycosphingolipid biosynthesis - globo series
    Glycosphingolipid biosynthesis - ganglio series
    Metabolic pathways

    UniProtKB/Swiss-Prot: SIA4A_HUMAN, Q11201
    Pathway: Protein modification; protein glycosylation


    ST3GAL1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ST3GAL1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/42 Interacting proteins for ST3GAL1 (ENSP000003184454) via UniProtKB, MINT, STRING, and/or I2D (see all 42)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    B3GALT5ENSP000003433184STRING: ENSP00000343318
    C1GALT1ENSP000002231224STRING: ENSP00000223122
    C1GALT1C1ENSP000003043644STRING: ENSP00000304364
    CHST2ENSP000003079114STRING: ENSP00000307911
    ENSG00000236802ENSP000004148804STRING: ENSP00000414880
    About this table

    Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process TAS--
    GO:0006464cellular protein modification process TAS10504389
    GO:0006468protein phosphorylation IEA--
    GO:0006486protein glycosylation ----
    GO:0016266O-glycan processing TAS--

    ST3GAL1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    ST3GAL1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ST3GAL1 (SIA4A)

    10/13 HMDB Compounds for ST3GAL1 (see all 13)    About this table
    CompoundSynonyms CAS #PubMed Ids
    Cytidine monophosphate5'-CMP (see all 14)63-37-6--
    Cytidine monophosphate N-acetylneuraminic acidCMP-N-acetylneuraminate (see all 6)22-12-8--
    Ganglioside GM1 (18:1/12:0)1-O-[O-(N-acetyl-a-neuraminosyl)-(2)-O-[O-b-D-galactopyranosyl-(1)-2-(acetylamino)-2-deoxy-b-D-galactopyranosyl-(1)]-O-b-D-galactopyranosyl-(1)-b-D-glucopyranosyl]-Ceramide (see all 17)104443-62-1--
    Ganglioside GM1 (18:1/16:0)1-O-[O-(N-acetyl-a-neuraminosyl)-(2)-O-[O-b-D-galactopyranosyl-(1)-2-(acetylamino)-2-deoxy-b-D-galactopyranosyl-(1)]-O-b-D-galactopyranosyl-(1)-b-D-glucopyranosyl]-Ceramide (see all 17)104443-62-1--
    Ganglioside GM1 (18:1/18:0)1-O-[O-(N-acetyl-a-neuraminosyl)-(2)-O-[O-b-D-galactopyranosyl-(1)-2-(acetylamino)-2-deoxy-b-D-galactopyranosyl-(1)]-O-b-D-galactopyranosyl-(1)-b-D-glucopyranosyl]-Ceramide (see all 17)104443-62-1--
    Ganglioside GM1 (18:1/20:0)1-O-[O-(N-acetyl-a-neuraminosyl)-(2)-O-[O-b-D-galactopyranosyl-(1)-2-(acetylamino)-2-deoxy-b-D-galactopyranosyl-(1)]-O-b-D-galactopyranosyl-(1)-b-D-glucopyranosyl]-Ceramide (see all 17)104443-62-1--
    Ganglioside GM1 (18:1/22:0)1-O-[O-(N-acetyl-a-neuraminosyl)-(2)-O-[O-b-D-galactopyranosyl-(1)-2-(acetylamino)-2-deoxy-b-D-galactopyranosyl-(1)]-O-b-D-galactopyranosyl-(1)-b-D-glucopyranosyl]-Ceramide (see all 17)104443-62-1--
    Ganglioside GM1 (18:1/9Z-18:1)1-O-[O-(N-acetyl-a-neuraminosyl)-(2)-O-[O-b-D-galactopyranosyl-(1)-2-(acetylamino)-2-deoxy-b-D-galactopyranosyl-(1)]-O-b-D-galactopyranosyl-(1)-b-D-glucopyranosyl]-Ceramide (see all 17)104443-62-1--
    Ganglioside GM1 (d18:1/24:0)1-O-[O-(N-acetyl-a-neuraminosyl)-(2)-O-[O-b-D-galactopyranosyl-(1)-2-(acetylamino)-2-deoxy-b-D-galactopyranosyl-(1)]-O-b-D-galactopyranosyl-(1)-b-D-glucopyranosyl]-Ceramide (see all 17)104443-62-1--
    Ganglioside GM1 (d18:1/24:1(15Z))1-O-[O-(N-acetyl-a-neuraminosyl)-(2)-O-[O-b-D-galactopyranosyl-(1)-2-(acetylamino)-2-deoxy-b-D-galactopyranosyl-(1)]-O-b-D-galactopyranosyl-(1)-b-D-glucopyranosyl]-Ceramide (see all 17)104443-62-1--

    3 Novoseek inferred chemical compound relationships for ST3GAL1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    gal(beta1-3)galnac 83 1 10561455 (1)
    sialic acid 66.8 7 10432010 (1), 11690653 (1), 16053379 (1), 10561455 (1)
    tetracycline 29 4 10745191 (1), 12209829 (1)

    Search CenterWatch for drugs/clinical trials and news about ST3GAL1 / SIA4A

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ST3GAL1 gene (2 alternative transcripts): 
    NM_003033.3  NM_173344.2  

    Unigene Cluster for ST3GAL1:

    ST3 beta-galactoside alpha-2,3-sialyltransferase 1
    Hs.374257  [show with all ESTs]
    Unigene Representative Sequence: NM_003033
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000521180(uc003yuk.2 uc003yum.2) ENST00000522652 ENST00000523854
    ENST00000517668 ENST00000522204 ENST00000523634 ENST00000519924 ENST00000523855
    ENST00000519435 ENST00000518298 ENST00000520020 ENST00000522873 ENST00000521627
    ENST00000522285 ENST00000319914 ENST00000399640
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ST3GAL1
    8/56 QIAGEN miScript miRNA Assays for microRNAs that regulate ST3GAL1 (see all 56):
    hsa-miR-21* hsa-miR-3678-3p hsa-miR-140-5p hsa-miR-520e hsa-miR-302d hsa-let-7d hsa-miR-106a hsa-miR-223
    SwitchGear 3'UTR luciferase reporter plasmidST3GAL1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ST3GAL1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ST3GAL1
    Clone
    Products:
         
    OriGene clones in human, mouse for ST3GAL1 (see all 14)
    OriGene ORF clones in mouse, rat for ST3GAL1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): ST3GAL1 (NM_003033)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ST3GAL1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ST3GAL1
    Sirion Biotech Customized lentivirus for stable overexpression of ST3GAL1 
                         Customized lentivirus expression plasmids for stable overexpression of ST3GAL1 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ST3GAL1
    OriGene qSTAR qPCR primer pairs in human, mouse for ST3GAL1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ST3GAL1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ST3GAL1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ST3GAL1

    Additional mRNA sequence: 

    AF059321.1 AK024824.1 AK093867.1 AK311319.1 AL833743.1 BC018357.1 BC048803.1 BC063665.1 
    BX537506.1 BX648001.1 L13972.1 L29555.1 

    18 DOTS entries:

    DT.75185036  DT.100747437  DT.452310  DT.100036399  DT.40114271  DT.100644821  DT.100807375  DT.95138446 
    DT.91713477  DT.95204665  DT.95211901  DT.91713480  DT.91736839  DT.95179446  DT.101969836  DT.120636565 
    DT.91684832  DT.91919837 

    24/103 AceView cDNA sequences (see all 103):

    CN484735 AA285156 CD370551 NM_003033 CR604109 BQ045227 BF434864 BF970833 
    NM_173344 N84627 BE869266 BG024777 BQ652174 BX370091 BG821487 L13972 
    AA015645 BF941067 AL702198 BG324700 BG470348 CF785848 AL702117 BV203455 

    GeneLoc Exon Structure

    5/14 Alternative Splicing Database (ASD) splice patterns (SP) for ST3GAL1 (see all 14)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c ^ 8a · 8b ^ 9a · 9b · 9c · 9d ^ 10a · 10b · 10c ^ 11a · 11b ^ 12a · 12b ^ 13a ·
    SP1:                    -     -           -     -     -     -     -           -     -                       -                                         -         
    SP2:                    -     -           -     -     -     -     -           -     -                                                                 -         
    SP3:                    -     -                 -     -     -     -           -     -                                                                           
    SP4:                    -     -           -     -     -     -     -           -     -     -     -     -     -     -     -     -     -     -                     
    SP5:                    -     -           -     -     -     -     -     -     -     -                                                                           

    ExUns: 13b ^ 14 ^ 15 ^ 16a · 16b
    SP1:                              
    SP2:                              
    SP3:                              
    SP4:                              
    SP5:                              


    ECgene alternative splicing isoforms for ST3GAL1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ST3GAL1 expression in normal human tissues (normalized intensities)      ST3GAL1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCGTTACGCA
    ST3GAL1 Expression
    About this image


    ST3GAL1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/17 selected tissues (see all 17) fully expand
     
     Brain (Nervous System)    fully expand to see all 5 entries
             Cerebral Cortex
             brain/midbrain   
     
     Neural Tube (Nervous System)    fully expand to see all 4 entries
             Metencephalon
     
     Blood (Hematopoietic System)    fully expand to see all 3 entries
             bone marrow cd34+   
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Granulosa Cells Primary Follicle
     
     Gut Tube (Gastrointestinal Tract)
             Foregut

    See ST3GAL1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ST3GAL1

    SOURCE GeneReport for Unigene cluster: Hs.374257

    UniProtKB/Swiss-Prot: SIA4A_HUMAN, Q11201
    Tissue specificity: Expressed in several tissues. Highest expression in lung, liver, skeletal muscle, kidney,
    pancreas, spleen and placenta

        SABiosciences Expression via Pathway-Focused PCR Array including ST3GAL1: 
              Glycosylation in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for ST3GAL1
    OriGene qSTAR qPCR primer pairs in human, mouse for ST3GAL1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ST3GAL1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ST3GAL1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ST3GAL1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ST3GAL1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for ST3GAL1 gene from 4/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia St3gal11 , 5 ST3 beta-galactoside alpha-2,3-sialyltransferase 11, 5 81.9(n)1
    82.2(a)1
      15 (29.30 cM)5
    204421  NM_009177.41  NP_033203.11 
     671028755 
    chicken
    (Gallus gallus)
    Aves ST3GAL11 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 67.16(n)
    67.06(a)
      396140  NM_205217.1  NP_990548.1 
    lizard
    (Anolis carolinensis)
    Reptilia ST3GAL16
    --
    Uncharacterized protein
    66(a)
    42(a)
    1 ↔ 1
    possible ortholog
    4(1009100-1098724)
    4(134196754-134209680)
    zebrafish
    (Danio rerio)
    Actinopterygii st3gal1l36
    ST3GAL1 (5 of 5)6
    (see all 6)
    ST3 beta-galactoside alpha-2,3-sialyltransferase 1...
    ST3 beta-galactoside alpha-2,3-sialyltransferase 1...
    (see all 6)
    48(a)
    47(a)
    (see all 6)
    many → 1
    many → 1
    (see all 6)
    19(18348941-18359042)
    19(4501285-4504506)


    ENSEMBL Gene Tree for ST3GAL1 (if available)
    TreeFam Gene Tree for ST3GAL1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ST3GAL1 gene
    ST3GAL32  ST6GALNAC12  ST3GAL62  ST6GALNAC22  ST3GAL42  ST3GAL22  ST3GAL52  
    7 SIMAP similar genes for ST3GAL1 using alignment to 6 protein entries:     SIA4A_HUMAN (see all proteins):
    ST3GAL4    ST3GAL6    ST3GAL2    ST6GALNAC2    ST8SIA1    ST6GALNAC1
    ST8SIA5

    ST3GAL1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for ST3GAL1
    PGOHUM00000245551


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2901 SNPs in ST3GAL1 are shown (see all 2901)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0492254
    ----see VAR_0492252 N S mis40--------
    rs559097101,2
    C--129863028(+) AAAAA-/A/AAA 
            
    GCCAT
    2 -- int11NA 2
    rs667624141,2
    C--129882847(-) CTCGC-/TCTTTCTT/
    TCTTTCTTTCTT
    TCTTT
    2 -- int12NA 4
    rs1493095801,2
    C--134466635(+) GGGAG-/AATTAG 2 -- ds50010--------
    rs1866222031,2
    --134466692(+) TCTGTC/TGGGGG 2 -- ds50010--------
    rs7603301,2
    C,F,A,H--134466779(-) CCAGTA/GGACAT 2 -- ds500110Minor allele frequency- G:0.07NA EA NS WA CSA 588
    rs737087901,2
    C,F--134466844(+) GTCGCG/ACCCAT 2 -- ds50013Minor allele frequency- A:0.05WA CSA 122
    rs1143907201,2
    F--134466852(+) CATTTA/GATACA 2 -- ds50011Minor allele frequency- G:0.01WA 118
    rs2000304671,2
    --134466863(+) GAGAC-/AACGCA 2 -- ds50010--------
    rs610399301,2
    C,F--134466891(+) TTAGGT/CGACTC 2 -- ds50012Minor allele frequency- C:0.04WA 120

    HapMap Linkage Disequilibrium report for ST3GAL1 (134467091 - 134584183 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for ST3GAL1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv6404CNV Insertion18451855
    nsv528683CNV Loss19592680
    nsv6405CNV Loss18451855
    nsv831464CNV Loss17160897
    nsv891457CNV Loss21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ST3GAL1
    DNA2.0 Custom Variant and Variant Library Synthesis for ST3GAL1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607187    OMIM disorders: --

    11 diseases for ST3GAL1:    About MalaCards
    morquio syndrome b    graves' disease    colon adenocarcinoma    bipolar disorder
    hypoxia    adenocarcinoma    breast cancer    colon cancer
    squamous cell carcinoma    colorectal cancer    thyroiditis


    ST3GAL1 for disorders           About GeneDecksing

    6 Novoseek inferred disease relationships for ST3GAL1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    colon cancer 31.2 1 7630014 (1)
    carcinoma 24.4 2 16112178 (1), 11585423 (1)
    breast carcinoma 22.9 4 10561455 (3)
    breast cancer 21.8 2 12841680 (1), 9751611 (1)
    cancer 12.3 1 15141079 (1)
    tumors 0 1 12841680 (1)

    Genetic Association Database (GAD): ST3GAL1
    Human Genome Epidemiology (HuGE) Navigator: ST3GAL1 (6 documents)

    Export disorders for ST3GAL1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ST3GAL1 gene, integrated from 9 sources (see all 53):
    (articles sorted by number of sources associating them with ST3GAL1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and expression of Galbeta1,3GalNAc alpha2, 3- sialyltransferase from human fetal liver. (PubMed id 10504389)1, 2, 3, 9 Shang J.... Jin C. (1999)
    2. Three genes that encode human beta-galactoside alpha 2,3- sialyltransferases. Structural analysis and chromosomal mapping studies. (PubMed id 7655169)1, 2, 3, 9 Chang M.-L.... Lau J.T.Y. (1995)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    4. Molecular genetics of successful smoking cessation: convergent genome-wide association study results. (PubMed id 18519826)1, 4 Uhl G.R....Lerman C. (2008)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Differential expression of five sialyltransferase genes in human tissues. (PubMed id 8027041)1, 2 Kitagawa H. and Paulson J.C. (1994)
    7. Family-based association study of lithium-related and other candidate genes in bipolar disorder. (PubMed id 18180429)1, 9 Perlis R.H....Sklar P. (2008)
    8. Sialyl-Lewis(x) on P-selectin glycoprotein ligand-1 is regulated during differentiation and maturation of dendritic cells: a mechanism involving the glycosyltransferases C2GnT1 and ST3Gal I. (PubMed id 17947642)1, 9 Julien S....Burchell J.M. (2007)
    9. Thyroid sialyltransferase mRNA level and activity are increased in Graves' disease. (PubMed id 16053379)1, 9 Kiljanski J....Bartoszewicz Z. (2005)
    10. Delineation of the minimal catalytic domain of human Galbeta1-3GalNAc alpha2,3-sialyltransferase (hST3Gal I). (PubMed id 11690653)1, 9 Vallejo-Ruiz V....Harduin-Lepers A. (2001)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6482 HGNC: 10862 AceView: SIAT4A Ensembl:ENSG00000008513 euGenes: HUgn6482
    ECgene: ST3GAL1 Kegg: 6482 H-InvDB: ST3GAL1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ST3GAL1 Pharmacogenomics, SNPs, Pathways
    GGDBhttp://riodb.ibase.aist.go.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=ST3GAL1
    Functional Glycomics Gateway - GTasehttp://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_622

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ST3GAL1 gene:
    Search GeneIP for patents involving ST3GAL1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Recombinant/Natural Proteins for ST3GAL1 (ST3 beta-Gal alpha-2,3-Sialyltransferase 1/ST3GAL1)  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for ST3GAL1   OriGene RNAi products in human, mouse, rat for ST3GAL1  
     OriGene qPCR primer pairs and template standards for ST3GAL1   OriGene Protein Over-expression Lysate for ST3GAL1  
     OriGene MassSpec something-or-other for ST3GAL1   OriGene clones in human, mouse for ST3GAL1  
     OriGene qSTAR qPCR primer pairs in human, mouse for ST3GAL1   OriGene Purified Protein for ST3GAL1  
     OriGene ORF clones in mouse, rat for ST3GAL1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ST3GAL1   OriGene Custom Protein Services for ST3GAL1  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ST3GAL1
     QIAGEN SeqTarget long-range PCR primers for resequencing ST3GAL1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ST3GAL1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ST3GAL1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ST3GAL1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ST3GAL1
     GenScript Custom Purified and Recombinant Proteins Services for ST3GAL1 GenScript cDNA clones with any tag delivered in your preferred vector for ST3GAL1
     GenScript Custom Assay Services for ST3GAL1 GenScript Custom Superior Antibodies Services for ST3GAL1
     GenScript Custom overexpressing Cell Line Services for ST3GAL1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in ST3GAL1 promoter
     Search Chromatin IP Primers for ST3GAL1
     RT2 qPCR Primer Assay in human, mouse, rat ST3GAL1
     Search GNC Networks for ST3GAL1
     SABiosciences PCR Arrays including human, mouse, rat ST3GAL1
     Search Tocris compounds for ST3GAL1 (SIA4A)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     cDNA Clones for ST3GAL1
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     ST3GAL1 antibodies
     ST3GAL1 proteins
     ST3GAL1 lysates
     Antibodies for ST3GAL1
     See all of Abcam's Antibodies, Kits and Proteins for ST3GAL1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.
     Search LifeMap BioReagents cell lines for ST3GAL1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ST3GAL1
     SwitchGear 3'UTR luciferase reporter plasmids for ST3GAL1
     SwitchGear Promoter luciferase reporter plasmids for ST3GAL1
     ThermoFisher Antibodies for ST3GAL1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ST3GAL1
     inGenious Targeting Laboratory - Custom generated mouse model solutions for ST3GAL1
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ST3GAL1
    Customized:
     lentivirus for stable overexpression of ST3GAL1
     lentivirus expression plasmids for stable overexpression of ST3GAL1
     adenovirus for overexpression of ST3GAL1
     LSBio Antibodies in human, mouse, rat for ST3GAL1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ST3GAL1 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4