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Aliases for ST20-MTHFS Gene

Aliases for ST20-MTHFS Gene

  • ST20-MTHFS Readthrough 2 3

External Ids for ST20-MTHFS Gene

Previous GeneCards Identifiers for ST20-MTHFS Gene

  • GC15U901328
  • GC15M080140

Summaries for ST20-MTHFS Gene

Entrez Gene Summary for ST20-MTHFS Gene

  • This locus represents naturally occurring read-through transcription between the neighboring suppressor of tumorigenicity 20 and 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) genes on chromosome 15. The read-through transcript produces a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Dec 2010]

GeneCards Summary for ST20-MTHFS Gene

ST20-MTHFS (ST20-MTHFS Readthrough) is a Protein Coding gene. Among its related pathways are Metabolism and One carbon pool by folate. An important paralog of this gene is MTHFS.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ST20-MTHFS Gene

Genomics for ST20-MTHFS Gene

Genomic Location for ST20-MTHFS Gene

79,843,547 bp from pter
79,923,754 bp from pter
80,208 bases
Minus strand

Genomic View for ST20-MTHFS Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ST20-MTHFS Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ST20-MTHFS Gene

No data available for Regulatory Elements for ST20-MTHFS Gene

Proteins for ST20-MTHFS Gene

  • Protein details for ST20-MTHFS Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    5-formyltetrahydrofolate cyclo-ligase
    Protein Accession:
    Secondary Accessions:

    Protein attributes for ST20-MTHFS Gene

    179 amino acids
    Molecular mass:
    20519 Da
    Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
    Quaternary structure:
    No Data Available

neXtProt entry for ST20-MTHFS Gene

Proteomics data for ST20-MTHFS Gene at MOPED

Post-translational modifications for ST20-MTHFS Gene

No Post-translational modifications

Other Protein References for ST20-MTHFS Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ST20-MTHFS Gene

Domains for ST20-MTHFS Gene

Protein Domains for ST20-MTHFS Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ST20-MTHFS: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ST20-MTHFS Gene

Function for ST20-MTHFS Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ST20-MTHFS Gene

Localization for ST20-MTHFS Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ST20-MTHFS Gene

Pathways for ST20-MTHFS Gene

genes like me logo Genes that share pathways with ST20-MTHFS: view

Pathways by source for ST20-MTHFS Gene

1 BioSystems pathway for ST20-MTHFS Gene
2 KEGG pathways for ST20-MTHFS Gene

Interacting Proteins for ST20-MTHFS Gene

Gene Ontology (GO) - Biological Process for ST20-MTHFS Gene


Transcripts for ST20-MTHFS Gene

mRNA/cDNA for ST20-MTHFS Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ST20-MTHFS Gene

No ASD Table

Relevant External Links for ST20-MTHFS Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ST20-MTHFS Gene

mRNA expression in normal human tissues for ST20-MTHFS Gene

Protein differential expression in normal tissues for ST20-MTHFS Gene

This gene is overexpressed in Liver (19.7), Peripheral blood mononuclear cells (12.1), and Gallbladder (6.6).

Integrated Proteomics: protein expression from PaxDb and MaxQB for ST20-MTHFS Gene

genes like me logo Genes that share expressions with ST20-MTHFS: view

Expression partners for ST20-MTHFS Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ST20-MTHFS Gene

Orthologs for ST20-MTHFS Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ST20-MTHFS Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia MTHFS 36
  • 69 (a)
(Canis familiaris)
Mammalia -- 36
  • 70 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 68 (a)
-- 36
  • 68 (a)
(Mus musculus)
Mammalia Gm2382 36
  • 70 (a)
Mthfs 36
  • 70 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 71 (a)
(Pan troglodytes)
Mammalia MTHFS 36
  • 81 (a)
(Gallus gallus)
Aves MTHFS 36
  • 56 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 67 (a)
(Danio rerio)
Actinopterygii MTHFS 36
  • 50 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG34424 36
  • 28 (a)
(Caenorhabditis elegans)
Secernentea Y106G6E.4 36
  • 31 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes FAU1 36
  • 24 (a)
Species with no ortholog for ST20-MTHFS:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ST20-MTHFS Gene

Gene Tree for ST20-MTHFS (if available)
Gene Tree for ST20-MTHFS (if available)

Paralogs for ST20-MTHFS Gene

Paralogs for ST20-MTHFS Gene

genes like me logo Genes that share paralogs with ST20-MTHFS: view

Variants for ST20-MTHFS Gene

Structural Variations from Database of Genomic Variants (DGV) for ST20-MTHFS Gene

Variant ID Type Subtype PubMed ID
nsv833065 CNV Loss 17160897
esv28440 CNV Loss 19812545
esv2678719 CNV Deletion 23128226
nsv833066 CNV Loss 17160897
esv2660680 CNV Deletion 23128226
nsv510406 CNV Loss 20534489
esv2672391 CNV Deletion 23128226
nsv904435 CNV Gain 21882294
dgv155n21 CNV Loss 19592680

Relevant External Links for ST20-MTHFS Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for ST20-MTHFS Gene

Disorders for ST20-MTHFS Gene

No disorders were found for ST20-MTHFS Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for ST20-MTHFS Gene

Publications for ST20-MTHFS Gene

  1. Genome-wide association study of chronic periodontitis in a general German population. (PMID: 24024966) Teumer A. … Kocher T. (J. Clin. Periodontol. 2013) 3

Products for ST20-MTHFS Gene

Sources for ST20-MTHFS Gene

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