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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ST18 Gene

protein-coding GIFtS: 54
GCID: GC08M053073

Suppression Of Tumorigenicity 18 (Breast Carcinoma) (Zinc...

(Previous name: zinc finger protein 387)
(Previous symbol: ZNF387)

See related diseases
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
Suppression Of Tumorigenicity 18 (Breast Carcinoma) (Zinc Finger Protein)¹ ²
Zinc Finger Protein 387¹ ² ³
ZNF387¹ ² ³
ZC2HC10²
Suppression Of Tumorigenicity 18 Protein²
KIAA0535³

External Ids:	HGNC: 18695¹	Entrez Gene: 9705²	Ensembl: ENSG00000147488⁷	UniProtKB: O60284³

Export aliases for ST18 gene to outside databases

Previous GC identifers: GC08M053028 GC08M052746 GC08M053185 GC08M048491

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ST18 Gene:

ST18 (suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)) is a protein-coding gene. Diseases associated with ST18 include facial paralysis, and primary angle-closure glaucoma. GO annotations related to this gene include DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is MYT1L.

UniProtKB/Swiss-Prot: ST18_HUMAN, O60284

Function: Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of

the sequence 5'-AAAGTTT-3' separated by 2-9 nucleotides. Represses basal transcription activity from target

promoters (By similarity). Inhibits colony formation in cultured breast cancer cells

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000008.10 NT_008183.19 NC_018919.2

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ST18 gene promoter:
C/EBPbeta CUTL1 Nkx2-5 NF-AT NF-AT4 NF-AT2 POU2F1 POU2F1a NF-AT3 NF-AT1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): ST18 promoter sequence

Search SABiosciences Chromatin IP Primers for ST18

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ST18

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q11.23 Ensembl cytogenetic band: 8q11.23 HGNC cytogenetic band: 8q11.23

ST18 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ST18 gene location

GeneLoc information about chromosome 8 GeneLoc Exon Structure

GeneLoc location for GC08M053073: view genomic region (about GC identifiers)

Start:	53,023,392 bp from pter	End:	53,373,519 bp from pter
Size:	350,128 bases	Orientation:	minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ST18_HUMAN, O60284 (See protein sequence)

Recommended Name: Suppression of tumorigenicity 18 protein

Size: 1047 amino acids; 115155 Da

Subcellular location: Nucleus

1 PDB 3D structure from and Proteopedia for ST18:

2CS8 (3D)

Secondary accessions: Q17RY1

Explore the universe of human proteins at neXtProt for ST18: NX_O60284

Explore proteomics data for ST18 at MOPED

Post-translational modifications:

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_O60284

ST18 Protein expression data from MOPED¹, PaxDb² and MAXQB³ : About this image

REFSEQ proteins: NP_055497.1

ENSEMBL proteins:

ENSP00000276480 ENSP00000429579 ENSP00000428920 ENSP00000430763 ENSP00000428521

ENSP00000428096

Human Recombinant Protein Products for ST18:

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	Novus Biologicals ST18 Protein Novus Biologicals ST18 Lysate
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	Cloud-Clone Corp. Proteins for ST18

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--

ST18 for ontologies About GeneDecksing

ST18 Antibody Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

HGNC Gene Families:

ZC2HC: Zinc fingers, C2HC-type containing

2 InterPro protein domains:

IPR002515 Znf_C2HC

IPR013681 Myelin_TF

Graphical View of Domain Structure for InterPro Entry O60284

ProtoNet protein and cluster: O60284

1 Blocks protein domain: IPB013681 Myelin transcription factor 1

UniProtKB/Swiss-Prot: ST18_HUMAN, O60284

Similarity: Contains 6 C2HC-type zinc fingers

ST18 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: ST18_HUMAN, O60284

Function: Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of

the sequence 5'-AAAGTTT-3' separated by 2-9 nucleotides. Represses basal transcription activity from target

promoters (By similarity). Inhibits colony formation in cultured breast cancer cells

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	IEA	--
GO:0003700	sequence-specific DNA binding transcription factor activity	IEA	--
GO:0008270	zinc ion binding	IEA	--

ST18 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for ST18:

Synthetic lethal with c-Myc af

1 MGI mutant phenotype (inferred from 1 allele) (MGI details for St18):

homeostasis/metabolism

ST18 for phenotypes About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Custom generated mouse model solutions for ST18

inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ST18

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ST18

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ST18

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ST18
		8/54 QIAGEN miScript miRNA Assays for microRNAs that regulate ST18 (see all 54):
		hsa-miR-3685 hsa-miR-323-3p hsa-miR-4317 hsa-miR-300 hsa-miR-875-5p hsa-let-7a-2* hsa-miR-301a hsa-miR-138-2*

		SwitchGear 3'UTR luciferase reporter plasmid: ST18 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		GenScript: all cDNA clones in your preferred vector: ST18 (NM_014682)
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for ST18
		Search LifeMap BioReagents cell lines for ST18

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ST18

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for ST18

1 Interacting protein for ST18 (O60284³) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PSMC5	P62195³	I2D: score=1

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006351	transcription, DNA-dependent	IEA	--
GO:0006355	regulation of transcription, DNA-dependent	--	--

ST18 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ST18

Search CenterWatch for drugs/clinical trials and news about ST18

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ST18 gene:

NM_014682.2

Unigene Cluster for ST18:

Suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)

Hs.655499 [show with all ESTs]

Unigene Representative Sequence: NM_014682

18/24 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 24):

ENST00000276480(uc011ldq.1 uc011ldr.1 uc003xqz.2 uc011lds.1 uc003xra.2 uc003xrb.2)

ENST00000521824 ENST00000522251 ENST00000521582 ENST00000518053 ENST00000522861

ENST00000518501 ENST00000517580 ENST00000520257 ENST00000521549(uc010lyb.2)

ENST00000518037 ENST00000517456 ENST00000519118 ENST00000518545 ENST00000521119

ENST00000518453 ENST00000520279 ENST00000519201

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ST18
		8/54 QIAGEN miScript miRNA Assays for microRNAs that regulate ST18 (see all 54):
		hsa-miR-3685 hsa-miR-323-3p hsa-miR-4317 hsa-miR-300 hsa-miR-875-5p hsa-let-7a-2* hsa-miR-301a hsa-miR-138-2*

		SwitchGear 3'UTR luciferase reporter plasmid: ST18 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ST18

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		GenScript: all cDNA clones in your preferred vector: ST18 (NM_014682)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for ST18
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ST18
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ST18

Additional mRNA sequence:

AB011107.1 AK311188.1 BC025662.1 BC026316.1 BC031075.1 BC117147.1 BC117149.1 BC143871.1

BC143872.1 BC143873.1 BC143875.1

10 DOTS entries:

DT.412961 DT.92036482 DT.40253060 DT.97834849 DT.91747483 DT.95179296 DT.91892517 DT.120635610

DT.120635615 DT.97764366

24/76 AceView cDNA sequences (see all 76):

BX282064 BP362876 BX642514 BE670703 AI298474 AI350226 BQ953938 AI298782

BG216577 BX953856 AB011107 NM_014682 BG218123 AA102556 AI741795 BG149419

BQ013076 CF529426 CB989836 BQ011733 BC025662 BC026316 AW770749 CB989259

GeneLoc Exon Structure

5/19 Alternative Splicing Database (ASD) splice patterns (SP) for ST18 (see all 19) About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	·	1e	·	1f	^	2	^	3a	·	3b	^	4a	·	4b	^	5	^	6	^	7	^	8	^	9	^	10a	·	10b	^	11a	·	11b	·	11c	^	12a	·	12b	^	13a	·	13b	·	13c	^
SP1:													-				-		-		-		-		-		-		-		-				-		-								-
SP2:													-				-		-		-		-		-		-		-		-				-		-								-
SP3:																																			-		-								-
SP4:																																			-		-								-				-		-
SP5:																																			-		-								-		-		-		-

ExUns:	14a	·	14b	·	14c	^	15	^	16	^	17	^	18a	·	18b	^	19	^	20	^	21	^	22	^	23	^	24a	·	24b	^	25	^	26a	·	26b	^	27	^	28a	·	28b	^	29a	·	29b	·	29c	^	30	^	31	^
SP1:									-																								-						-				-
SP2:	-								-
SP3:	-
SP4:	-
SP5:	-

ExUns:	32	^	33	^	34
SP1:
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for ST18

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ST18 expression in normal human tissues (normalized intensities) ST18 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: AAACTTTGGT

About this image

ST18 expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database

5/9 selected tissues (see all 9) fully expand


Pancreas (Endocrine System) fully expand to see all 4 entries
Endocrine Progenitor Cells Ventral Pancreatic Bud

Brain (Nervous System) fully expand to see all 4 entries
corpus callosum

Bone (Muscoskeletal System)
Zeugopod Periosteum

Head Mesenchyme (Muscoskeletal System)
Frontonasal Process

Eye (Sensory Organs)
nGnG Amacrine Cells Inner Nuclear Layer

See ST18 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ST18

SOURCE GeneReport for Unigene cluster: Hs.655499

UniProtKB/Swiss-Prot: ST18_HUMAN, O60284

Tissue specificity: Detected at low levels in heart, liver, kidney, skeletal muscle, pancreas, testis, ovary and

prostate. Detected at even lower levels in mammary epithelial cells and breast cancer cells

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ST18

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for ST18 gene from 5/13 species (see all 13) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	St18^{1 , 5}	suppression of tumorigenicity 18^{1, 5}	85.36(n)¹ 85.07(a)¹		1 (1.89 cM)⁵ 240690¹ NM_001244692.1¹ NP_001231621.1¹ 6487231⁵
chicken (Gallus gallus)	Aves	ST18¹	suppression of tumorigenicity 18 (breast carcinoma) more	79.66(n) 80.46(a)		421115 XM_419199.2 XP_419199.2
lizard (Anolis carolinensis)	Reptilia	ST18⁶	suppression of tumorigenicity 18 (breast carcinoma...	73(a)	1 ↔ 1	GL343244.1(1850523-2098155)
zebrafish (Danio rerio)	Actinopterygii	st18⁶	suppression of tumorigenicity 18 (breast carcinoma...	59(a)	1 ↔ 1	24(36615702-36657091)
fruit fly (Drosophila melanogaster)	Insecta	CG43689⁶	--	10(a)	possible ortholog	X(3970107-3986186)

ENSEMBL Gene Tree for ST18 (if available)
TreeFam Gene Tree for ST18 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for ST18 gene

MYT1L² MYT1²

2 SIMAP similar genes for ST18 using alignment to 7 protein entries: ST18_HUMAN (see all proteins):

MYT1 MYT1L

ST18 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 8 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs190174460^1,2	C	--	53023051(+)	`TATACC/TCCGTA`	1	--	ds500¹		0	--	--	--	--
rs148535846^1,2	C	--	53023053(+)	`TACTCC/TGTATC`	1	--	ds500¹		0	--	--	--	--
rs62500972^1,2	C,F	--	53023095(+)	`CTCTAT/CCTTGC`	1	--	ds500¹		6		NA CSA WA EA	364
rs193127082^1,2		--	53023154(+)	`CCTTAC/TGTCAA`	1	--	ds500¹		0	--	--	--	--
rs141815191^1,2		--	53023225(+)	`CAAAAA/GTCCTG`	1	--	ds500¹		0	--	--	--	--
rs184687439^1,2		--	53023276(+)	`GTCTCC/TGAATG`	1	--	ds500¹		0	--	--	--	--
rs117466701^1,2	C,F	--	53023279(+)	`TCCGAA/GTGACT`	1	--	ds500¹		1		NA	120
rs150613667^1,2		--	53023307(+)	`TCTGGG/TGACCT`	1	--	ds500¹		0	--	--	--	--
rs6994915^1,2	C,F,H	--	53023384(+)	`AGAAAG/AATCAC`	1	--	ds500¹		9		NS NA	1164
rs188308014^1,2		--	53023389(+)	`GATCAA/CATCAA`	1	--	ds500¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for ST18 (53023392 - 53273392 bp, first 250kb of ST18)

Structural Variations
Database of Genomic Variants (DGV) 4 variations for ST18: About this table

Variant ID	Type	Subtype	PubMed ID
esv270428	CNV	Insertion	20981092
esv2636600	CNV	Insertion	19546169
dgv7794n71	CNV	Gain	21882294
nsv831317	CNV	Gain	17160897

SABiosciences Cancer Mutation PCR Assays

SeqTarget long-range PCR primers for resequencing ST18

DNA2.0 Custom Variant and Variant Library Synthesis for ST18

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

9 diseases for ST18: About MalaCards

facial paralysis primary angle-closure glaucoma paralysis pemphigus vulgaris

pemphigus glaucoma retinitis breast cancer

prostatitis

1 disease from the University of Copenhagen DISEASES database for ST18:

Primary angle-closure glaucoma

ST18 for disorders About GeneDecksing

Genetic Association Database (GAD): ST18
Human Genome Epidemiology (HuGE) Navigator: ST18 (1 document)

Export disorders for ST18 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for ST18 gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with ST18)

Utopia: connect your pdf to the dynamic
world of online information

ST18 is a breast cancer tumor suppressor gene at human chromosome 8q11.2. (PubMed id 15489893)^{1, 2, 3, 9} Jandrig B....Rosenthal A. (2004)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)^{1, 4} Rose J.E....Uhl G.R. (2010)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9628581)^{1, 2} Nagase T....Ohara O. (1998)
Genotype-phenotype analysis of SNPs associated with pr imary angle closure glaucoma (rs1015213, rs3753841 and rs11024102) and ocular bi ometry in the EPIC-Norfolk Eye Study. (PubMed id 23505305)¹ Day A.C....Foster P.J. (2013)
Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. (PubMed id 23535033)¹ Sherva R....Green R.C. (2013)
Population-specific association between a polymorphic variant in ST18, encoding a pro-apoptotic molecule, and pemphigus vulgaris. (PubMed id 22437316)¹ Sarig O....Sprecher E. (2012)
The transcription factor ST18 regulates proapoptotic and proinflammatory gene expression in fibroblasts. (PubMed id 18676404)¹ Yang J....Graves D.T. (2008)
Genome-wide association with bone mass and geometry in the Framingham Heart Study. (PubMed id 17903296)⁴ Kiel D.P....Karasik D. (2007)
Genome-wide association with select biomarker traits in the Framingham Heart Study. (PubMed id 17903293)⁴ Benjamin E.J....Vasan R.S. (2007)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 9705	HGNC: 18695	AceView: ST18	Ensembl:ENSG00000147488	euGenes: HUgn9705
ECgene: ST18	H-InvDB: ST18

(According to HUGE)
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HUGE: KIAA0535

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for ST18	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for ST18	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for ST18 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for ST18 gene:
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GeneCards and IP:
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