Aliases for ST18 Gene
Aliases for ST18 Gene
External Ids for ST18 Gene
- HGNC: 18695
- Entrez Gene: 9705
- Ensembl: ENSG00000147488
- OMIM: 617155
- UniProtKB: O60284
Previous HGNC Symbols for ST18 Gene
- ZNF387
Previous GeneCards Identifiers for ST18 Gene
- GC08M053028
- GC08M052746
- GC08M053073
- GC08M053185
- GC08M048491
- GC08M053023
Summaries for ST18 Gene
GeneCards Summary for ST18 Gene
ST18 (ST18, C2H2C-Type Zinc Finger) is a Protein Coding gene. Diseases associated with ST18 include Breast Cancer. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity. An important paralog of this gene is MYT1.
UniProtKB/Swiss-Prot for ST18 Gene
-
Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5-AAAGTTT-3 separated by 2-9 nucleotides. Represses basal transcription activity from target promoters (By similarity). Inhibits colony formation in cultured breast cancer cells.
Additional gene information for ST18 Gene
- Monarch Initiative
- Search for ST18 at DataMed
- Search for ST18 at HumanCyc
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ST18 Gene
Genomics for ST18 Gene
GeneHancer (GH) Regulatory Elements for ST18 Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH08I052460 | Enhancer | 0.8 | Ensembl ENCODE | 562.2 | +0.3 | 322 | 1.1 | SMARCC1 JUN USF2 MAX CEBPB EP300 JUND POLR2A FOS | ST18 ALKAL1 GC08M052343 | |
GH08I052409 | Promoter/Enhancer | 0.7 | EPDnew dbSUPER | 550.2 | +51.2 | 51183 | 0.1 | ST18 GC08M052343 GC08P052343 | ||
GH08I052329 | Promoter | 0.5 | EPDnew | 550.1 | +131.7 | 131657 | 0.1 | ST18 GC08M052338 RPL34P17 | ||
GH08I052459 | Enhancer | 0.2 | FANTOM5 | 550.8 | +1.2 | 1155 | 0.1 | ST18 RB1CC1 GC08M052343 | ||
GH08I052466 | Enhancer | 1.4 | FANTOM5 Ensembl ENCODE | 12.9 | -6.4 | -6380 | 1.5 | PKNOX1 CLOCK FOXA2 ZFP64 SIN3A BRCA1 GLIS2 FOS RUNX3 SMARCB1 | ST18 ALKAL1 RB1CC1 GC08M052509 |
Regulatory Element Products
Genomic Locations for ST18 Gene
- chr8:52,110,832-52,460,959
- (GRCh38/hg38)
- Size:
- 350,128 bases
- Orientation:
- Minus strand
- chr8:53,023,392-53,373,519
- (GRCh37/hg19)
Genomic View for ST18 Gene
- Cytogenetic band:
-
- 8q11.23 by Ensembl
- 8q11.23 by Entrez Gene
- 8q11.23 by HGNC


RefSeq DNA sequence for ST18 Gene
Proteins for ST18 Gene
-
Protein details for ST18 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O60284-ST18_HUMAN
- Recommended name:
- Suppression of tumorigenicity 18 protein
- Protein Accession:
- O60284
- Q17RY1
Protein attributes for ST18 Gene
- Size:
- 1047 amino acids
- Molecular mass:
- 115155 Da
- Quaternary structure:
- No Data Available
Protein Expression for ST18 Gene
Post-translational modifications for ST18 Gene
Other Protein References for ST18 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
-
- NP_001339755.1
- NP_001339756.1
- NP_001339757.1
- NP_001339758.1
- NP_001339759.1
- NP_001339760.1
- NP_001339761.1
- NP_001339762.1
- NP_001339763.1
- NP_001339764.1
- NP_001339765.1
- NP_001339766.1
- NP_001339767.1
- NP_001339768.1
- NP_001339769.1
- NP_001339770.1
- NP_001339771.1
- NP_001339772.1
- NP_001339773.1
- NP_001339774.1
- NP_001339775.1
- NP_001339776.1
- NP_001339777.1
- NP_001339778.1
- NP_001339779.1
- NP_001339780.1
- NP_001339781.1
- NP_001339782.1
- NP_001339783.1
- NP_001339784.1
- NP_001339785.1
- NP_001339786.1
- NP_001339787.1
- NP_001339788.1
- NP_001339789.1
- NP_001339790.1
- NP_001339791.1
- NP_001339792.1
- NP_001339793.1
- NP_001339794.1
- NP_001339795.1
- NP_001339796.1
- NP_001339797.1
- NP_001339798.1
- NP_001339799.1
- NP_001339800.1
- NP_001339801.1
- NP_001339802.1
- NP_001339803.1
- NP_001339804.1
- NP_001339805.1
- NP_001339806.1
- NP_001339807.1
- NP_001339808.1
- NP_001339809.1
- NP_001339810.1
- NP_001339811.1
- NP_001339812.1
- NP_001339813.1
- NP_055497.1
- XP_006716550.1
- XP_011515931.1
- XP_011515933.1
- XP_011515934.1
- XP_011515935.1
- XP_011515936.1
- XP_011515937.1
- XP_011515938.1
- XP_011515939.1
- XP_011515940.1
- XP_011515943.1
- XP_011515944.1
- XP_016869536.1
- XP_016869537.1
- XP_016869538.1
- XP_016869539.1
- XP_016869540.1
- XP_016869541.1
- XP_016869542.1
- XP_016869543.1
- XP_016869544.1
- XP_016869545.1
- XP_016869546.1
- XP_016869547.1
- XP_016869548.1
- XP_016869549.1
- XP_016869550.1
- XP_016869551.1
- XP_016869552.1
- XP_016869553.1
- XP_016869554.1
- XP_016869555.1
- XP_016869556.1
- XP_016869557.1
- XP_016869558.1
- XP_016869559.1
- XP_016869560.1
- XP_016869561.1
- XP_016869562.1
- XP_016869563.1
- XP_016869564.1
- XP_016869565.1
- XP_016869566.1
- XP_016869567.1
- XP_016869568.1
- XP_016869569.1
- XP_016869570.1
- XP_016869571.1
- XP_016869572.1
- XP_016869573.1
Antibody Products
- Novus Biologicals Antibodies for ST18
-
Abcam antibodies for ST18
- Invitrogen Antibodies for ST18
- antibodies-online: Search results for available St18 related products ranked by validation data
- GeneTex ST18 antibody for ST18
Protein Products
-
OriGene Purified Proteins for ST18
- Search Origene for MassSpec and Protein Over-expression Lysates for ST18
- Origene Custom Protein Services for ST18
- antibodies-online: Search results for available St18 related products ranked by validation data
- Search GeneTex for Proteins for ST18
-
Abcam proteins for ST18
Assay Products
- antibodies-online: Search results for available St18 related products ranked by validation data
No data available for DME Specific Peptides for ST18 Gene
Domains & Families for ST18 Gene
Gene Families for ST18 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for ST18 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ST18 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O60284- Family:
-
- Belongs to the MYT1 family.
Function for ST18 Gene
Molecular function for ST18 Gene
- UniProtKB/Swiss-Prot Function:
- Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5-AAAGTTT-3 separated by 2-9 nucleotides. Represses basal transcription activity from target promoters (By similarity). Inhibits colony formation in cultured breast cancer cells.
Phenotypes From GWAS Catalog for ST18 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0001047 | core promoter binding | IDA | 18676404 |
GO:0003677 | DNA binding | IEA | -- |
GO:0003700 | DNA binding transcription factor activity | IEA | -- |
GO:0008270 | zinc ion binding | IEA | -- |
GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for ST18 Gene
- MGI mutant phenotypes for ST18:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ST18:
-
- Increased viability
- Increased vaccinia virus (VACV) infection
- shRNA abundance <= 50%
- Decreased NF-kappaB reporter expression
- Synthetic lethal with c-Myc after tamoxifen stimulation
- Decreased viability after Maraba virus infection
- Decreased IL-8 secretion
- Decreased shRNA abundance
- Negative genetic interaction between BLM-/- and BLM+/+
Animal Models for ST18 Gene
- MGI Knock Outs for ST18:
-
- St18 tm1a(KOMP)Wtsi
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ST18
-
-
ViGene Biosciences lentiviral particle packaged cDNA for ST18 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ST18 gene
- Search ViGene Biosciences for ST18
CRISPR Products
-
OriGene CRISPR knockouts for ST18
- genomics-online: gRNA clones - Search results for available St18 gene related products
- Applied Biological Materials CRISPR for ST18
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ST18
- GenScript: Design CRISPR guide RNA sequences for ST18
miRNA for ST18 Gene
- miRTarBase miRNAs that target ST18
-
- hsa-mir-26b-5p (MIRT030273)
- hsa-mir-580-3p (MIRT447456)
- hsa-mir-451b (MIRT447457)
- hsa-mir-1255a (MIRT783226)
- hsa-mir-1255b-5p (MIRT783229)
- hsa-mir-3691-5p (MIRT785283)
- hsa-mir-376b-5p (MIRT785368)
- hsa-mir-376c-5p (MIRT785371)
- hsa-mir-3911 (MIRT785430)
- hsa-mir-4711-3p (MIRT786502)
- hsa-mir-4752 (MIRT786612)
- hsa-mir-496 (MIRT786912)
- hsa-mir-574-5p (MIRT787884)
- hsa-mir-627-5p (MIRT788153)
- hsa-mir-6744-5p (MIRT788536)
- hsa-mir-6818-5p (MIRT788946)
- hsa-mir-6867-5p (MIRT789222)
- hsa-mir-8056 (MIRT789761)
- hsa-mir-924 (MIRT789952)
miRNA Products
- Search ViGene Biosciences for ST18
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for ST18
- Browse OriGene Inhibitory RNA Products For ST18
- genomics-online: shRNA clones - Search results for available St18 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for ST18 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ST18
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ST18
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available St18 gene related products
- orf clones - Search results for available St18 gene related products
- Applied Biological Materials Clones for ST18
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for ST18
-
ViGene Biosciences adenoviral particle packaged cDNA for ST18 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ST18 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ST18 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ST18 Gene
Localization for ST18 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ST18 Gene
- Nucleus.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IDA,IEA | 15489893 |
GO:0032993 | protein-DNA complex | IDA | 18676404 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for ST18 Gene
Pathways & Interactions for ST18 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006351 | transcription, DNA-templated | IEA | -- |
GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
GO:0008285 | negative regulation of cell proliferation | IDA | 15489893 |
GO:0033209 | tumor necrosis factor-mediated signaling pathway | IMP | 18676404 |
GO:0045944 | positive regulation of transcription by RNA polymerase II | IMP | 18676404 |
No data available for Pathways by source and SIGNOR curated interactions for ST18 Gene
Transcripts for ST18 Gene
mRNA/cDNA for ST18 Gene
- (110) REFSEQ mRNAs :
- (11) Additional mRNA sequences :
- (76) Selected AceView cDNA sequences:
- (24) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ST18 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ST18
- genomics-online: gRNA clones - Search results for available St18 gene related products
- Applied Biological Materials CRISPR for ST18
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ST18
- GenScript: Design CRISPR guide RNA sequences for ST18
miRNA Products
- Search ViGene Biosciences for ST18
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for ST18
- Browse OriGene Inhibitory RNA Products For ST18
- genomics-online: shRNA clones - Search results for available St18 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for ST18 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ST18
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ST18
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available St18 gene related products
- orf clones - Search results for available St18 gene related products
- Applied Biological Materials Clones for ST18
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | · | 1f | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | · | 11c | ^ | 12a | · | 12b | ^ | 13a | · | 13b | · | 13c | ^ |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
SP2: | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
SP3: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
SP4: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
SP5: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
SP6: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP7: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||
SP8: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
SP9: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP10: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP11: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP12: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
SP13: | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
SP14: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
SP15: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
SP16: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
SP17: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
SP18: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP19: | - |
ExUns: | 14a | · | 14b | · | 14c | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18a | · | 18b | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24a | · | 24b | ^ | 25 | ^ | 26a | · | 26b | ^ | 27 | ^ | 28a | · | 28b | ^ | 29a | · | 29b | · | 29c | ^ | 30 | ^ | 31 | ^ |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
SP2: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
SP3: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
SP4: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
SP5: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
SP6: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
SP7: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP9: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP10: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP11: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
SP12: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP13: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP14: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP15: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP16: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP17: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP18: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP19: |
ExUns: | 32 | ^ | 33 | ^ | 34 |
---|---|---|---|---|---|
SP1: | |||||
SP2: | |||||
SP3: | |||||
SP4: | |||||
SP5: | |||||
SP6: | |||||
SP7: | |||||
SP8: | |||||
SP9: | |||||
SP10: | |||||
SP11: | |||||
SP12: | |||||
SP13: | |||||
SP14: | |||||
SP15: | |||||
SP16: | |||||
SP17: | |||||
SP18: | |||||
SP19: |
Expression for ST18 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Pancreas (Endocrine System)
- Endocrine Progenitor Cells Dorsal Pancreatic Bud
- Bipotent Endocrine/Duct Progenitor Cells Dorsal Pancreatic Bud
- Endocrine Progenitor Cells Ventral Pancreatic Bud
- Bipotent Endocrine/Duct Progenitor Cells Ventral Pancreatic Bud
-
Epithelial Cells
- Endocrine Progenitor Cells Dorsal Pancreatic Bud
- Bipotent Endocrine/Duct Progenitor Cells Dorsal Pancreatic Bud
- Endocrine Progenitor Cells Ventral Pancreatic Bud
- Bipotent Endocrine/Duct Progenitor Cells Ventral Pancreatic Bud
-
Eye (Sensory Organs)
- nGnG Amacrine Cells Inner Nuclear Layer
-
Neurons
- nGnG Amacrine Cells Inner Nuclear Layer
-
Adipose (Muscoskeletal System)
- Mesenchymal Stem Cells Subcutaneous White Adipose
-
Mesenchymal Stem Cells
- Mesenchymal Stem Cells Subcutaneous White Adipose
- Head Mesenchyme (Muscoskeletal System)
- Neural Tube (Nervous System)
- Bone (Muscoskeletal System)
-
Spinal Cord (Nervous System)
-
Dermis (Integumentary System)
mRNA differential expression in normal tissues according to GTEx for ST18 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ST18 Gene
NURSA nuclear receptor signaling pathways regulating expression of ST18 Gene:
ST18SOURCE GeneReport for Unigene cluster for ST18 Gene:
Hs.655499mRNA Expression by UniProt/SwissProt for ST18 Gene:
O60284-ST18_HUMANEvidence on tissue expression from TISSUES for ST18 Gene
- Nervous system(4.6)
Primer Products
-
OriGene qPCR primer pairs for ST18
- genomics-online: primer clones - Search results for available St18 gene related products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for ST18 Gene
Orthologs for ST18 Gene
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | ST18 33 34 |
|
||
dog (Canis familiaris) |
Mammalia | ST18 33 34 |
|
||
rat (Rattus norvegicus) |
Mammalia | St18 33 |
|
||
mouse (Mus musculus) |
Mammalia | St18 33 16 34 |
|
||
cow (Bos Taurus) |
Mammalia | ST18 33 34 |
|
||
oppossum (Monodelphis domestica) |
Mammalia | ST18 34 |
|
OneToOne | |
platypus (Ornithorhynchus anatinus) |
Mammalia | ST18 34 |
|
OneToOne | |
chicken (Gallus gallus) |
Aves | ST18 33 34 |
|
||
lizard (Anolis carolinensis) |
Reptilia | ST18 34 |
|
OneToOne | |
tropical clawed frog (Silurana tropicalis) |
Amphibia | st18 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | st18 34 |
|
OneToOne | |
fruit fly (Drosophila melanogaster) |
Insecta | CG43689 34 |
|
OneToMany | |
worm (Caenorhabditis elegans) |
Secernentea | ztf-11 34 |
|
OneToMany | |
sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany | |
sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.9753 33 |
|
- Species where no ortholog for ST18 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for ST18 Gene
(2) SIMAP similar genes for ST18 Gene using alignment to 7 proteins:
Variants for ST18 Gene
SNP ID | Clin | Chr 08 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000004585 | -- | 52,359,480(-) | A/T | genic_upstream_transcript_variant, intron_variant | |
rs1000024418 | -- | 52,237,936(-) | C/G | intron_variant | |
rs1000053180 | -- | 52,147,263(-) | A/G | intron_variant | |
rs1000067850 | -- | 52,304,758(-) | C/T | genic_upstream_transcript_variant, intron_variant | |
rs1000069019 | -- | 52,186,158(-) | A/C | intron_variant |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv7218n100 | CNV | gain | 25217958 |
esv2636600 | CNV | insertion | 19546169 |
esv2761192 | CNV | gain | 21179565 |
esv3306151 | CNV | mobile element insertion | 20981092 |
esv3369035 | CNV | insertion | 20981092 |
esv3375181 | CNV | insertion | 20981092 |
esv3400120 | CNV | insertion | 20981092 |
esv3572759 | CNV | loss | 25503493 |
esv3617209 | CNV | loss | 21293372 |
esv3617210 | CNV | gain | 21293372 |
esv3617211 | CNV | gain | 21293372 |
esv3891395 | CNV | gain | 25118596 |
nsv1032281 | CNV | gain | 25217958 |
nsv831317 | CNV | gain | 17160897 |
Additional Variant Information for ST18 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ST18 Gene
Disorders for ST18 Gene
Disorder | Aliases | PubMed IDs |
---|---|---|
breast cancer |
|
|
Additional Disease Information for ST18
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for ST18 Gene
Publications for ST18 Gene
- ST18 is a breast cancer tumor suppressor gene at human chromosome 8q11.2. (PMID: 15489893) Jandrig B … Rosenthal A (Oncogene 2004) 2 3 4 22 58
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
- Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PMID: 9628581) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 1998) 3 4 58
- Identification of a Functional Risk Variant for Pemphigus Vulgaris in the ST18 Gene. (PMID: 27148741) Vodo D … Sprecher E (PLoS genetics 2016) 3 58
Products for ST18 Gene
- Browse R&D Systems for Antibodies
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- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for ST18
- Search Origene for MassSpec and Protein Over-expression Lysates for ST18
- Origene Custom Protein Services for ST18
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ST18
- Browse OriGene Inhibitory RNA Products For ST18
- OriGene qPCR primer pairs for ST18
- OriGene CRISPR knockouts for ST18
- OriGene ORF clones in human for ST18
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For ST18
- GenScript: Next-day shipping of latest version cDNA ORF clones for ST18 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for ST18
- GenScript Custom Assay Services for ST18
- GenScript Custom overexpressing Cell Line Services for ST18
- GenScript: Design CRISPR guide RNA sequences for ST18
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for ST18
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
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- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for ST18
- Novus Biologicals proteins and lysates for ST18
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for ST18
- Abcam proteins for ST18
- Find your target
- Browse Primary Antibodies
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- Browse Antibodies at Cloud-Clone Corp.
- Browse Proteins at Cloud-Clone Corp.
- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for ST18
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for ST18
- VectorBuilder custom plasmid, inducible vectors for ST18
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ST18
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for available St18 related products ranked by validation data
- antibodies-online: Search results for available St18 related products ranked by validation data
- antibodies-online: Search results for available St18 related products ranked by validation data
- GeneTex ST18 antibody for ST18
- Search GeneTex for Proteins for ST18
- ViGene Biosciences adenoviral particle packaged cDNA for ST18 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ST18 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ST18 gene
- Search ViGene Biosciences for ST18
- Horizon Cell Lines for ST18
- genomics-online: cdna clones - Search results for available St18 gene related products
- orf clones - Search results for available St18 gene related products
- genomics-online: gRNA clones - Search results for available St18 gene related products
- genomics-online: primer clones - Search results for available St18 gene related products
- genomics-online: shRNA clones - Search results for available St18 gene related products
Sources for ST18 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew