ST13P4 Gene
pseudogene GIFtS: 33
GCID: GC13P050747
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suppression of tumorigenicity 13 (colon carcinoma) (Hsp7...(Previous names: family with sequence similarity 10, member A4 pseudogene...)
(Previous symbol: FAM10A4)
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Aliases
for ST13P4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Suppression Of Tumorigenicity 13 (Colon Carcinoma) (Hsp70 InteractingProtein) Pseudogene 41 2 | | FAM10A41 2 3 | | FAM10A4P1 2 | | Family With Sequence Similarity 10, Member A4 Pseudogene1 | | Suppression Of Tumorigenicity 13 Pseudogene 43 |
| External Ids: | HGNC: 184871 | Entrez Gene: 1451652 | Ensembl: ENSG000002321507 | UniProtKB: Q8IZP23 | | ORGUL members: | |
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| NONCODE:n405439 | |
Export aliases for ST13P4 gene to outside databasesPrevious GC identifer: GC13P031541
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Summaries
for ST13P4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for ST13P4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000013.10 NC_018924.1 NT_024524.14
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for ST13P4
Other transcription factors
Search SABiosciences Chromatin IP Primers for ST13P4
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ST13P4 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 13q14.3 Ensembl cytogenetic band: 13q14.2 HGNC cytogenetic band: 13q14ST13P4 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 13 GeneLoc Exon Structure GeneLoc location for GC13P050747: view genomic region
(about GC identifiers)
Start:
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50,746,154 bp from pter |
End:
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50,747,752 bp from pter |
Size:
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1,599 bases |
Orientation:
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plus strand |
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Proteins
for ST13P4 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ST134_HUMAN, Q8IZP2 (See
protein sequence)Recommended Name: Putative protein FAM10A4 Size: 240 amino acids; 27407 Da
Subcellular location: Cytoplasm (Probable)
Caution: Could be the product of a pseudogeneExplore the universe of human proteins at neXtProt for ST13P4: NX_Q8IZP2
ST13P4 Protein expression data from MOPED and PaxDb: --
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005737 | cytoplasm |
IEA | -- |
ST13P4 for ontologies About GeneDecksing
ST13P4 Antibody Products:
Assay Products for ST13P4: |
Protein
Domains /
Families
for ST13P4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ST13P4 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8IZP2ProtoNet protein and cluster: Q8IZP2 UniProtKB/Swiss-Prot: ST134_HUMAN, Q8IZP2Similarity: Belongs to the FAM10 familySimilarity: Contains 3 TPR repeats |
Function
for ST13P4 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ST13P4 |
1 GenomeRNAi human phenotype for ST13P4:
|
Pathways & Interactions
for ST13P4 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ST13P4
1 Interacting protein for ST13P4 (Q8IZP22, 3) via UniProtKB, MINT, STRING, and/or I2DAbout this table
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Drugs & Compounds
for ST13P4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ST13P4
Search CenterWatch for drugs/clinical trials and news about ST13P4 
|
Transcripts
for ST13P4 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ST13P4 gene: NM_153290.1 Unigene Cluster for ST13P4: Suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) pseudogene 4 Hs.511834 [show with all ESTs]Unigene Representative Sequence: AF5394681 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000495613(uc001vej.3)
Additional cDNA sequence: AF539468.1 NR_002183.1 12 DOTS entries: DT.100000399 DT.100892017 DT.456282 DT.120774954 DT.99998054 DT.100034556 DT.100892030 DT.100892026 DT.100678206 DT.100757889 DT.100892025 DT.100892042 7 AceView cDNA sequences: NM_153290 AF539468 AI929839 BF089934 AW604071 CD579790 BX407161
GeneLoc Exon Structure
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Expression
for ST13P4 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ST13P4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
SOURCE GeneReport for Unigene cluster: Hs.511834
UniProtKB/Swiss-Prot: ST134_HUMAN, Q8IZP2Tissue specificity: Highly expressed in bone marrow and weakly in placenta, pancreas, heart and HeLa cell line
SABiosciences Custom PCR Arrays for ST13P4
Primer
Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ST13P4
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ST13P4 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ST13P4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ST13P4 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ST13P4 |
Orthologs
for ST13P4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of chordates.
Orthologs for ST13P4 gene from 1 species (see representative species ) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
Str.21232 |
Transcribed sequence with weak similarity to protein more |
77.91(n) |
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AL775197.2 |
Species with no ortholog for ST13P4
ENSEMBL Gene Tree for ST13P4 (if available)
TreeFam Gene Tree for ST13P4 (if available) |
Paralogs
for ST13P4 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ST13P4 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 13 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ST13P4 (50746154 - 50747752 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ST13P4: -- | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for ST13P4 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ST13P4 for disorders About GeneDecksing
11  diseases for ST13P4: About MalaCardscolon carcinoma carcinoma chronic lymphocytic leukemia lymphocytic leukemia
celiac disease multiple myeloma myeloma leukemia
t-cell leukemia prostate cancer prostatitis
Export disorders for ST13P4 gene to outside databases
|
Publications
for ST13P4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ST13P4 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ST13P4) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of FAM10A4, a member of the ST13 tumor suppressor gene family that maps to the 13q14.3 region associated with B-Cell leukemia, multiple myeloma, and prostate cancer. (PubMed id 12079276)1, 2 Sossey-Alaoui K.... Cowell J.K. (2002)
- The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Multiple common variants for celiac disease influenci ng immune gene expression. (PubMed id 20190752)1 Dubois P.C....van Heel D.A. (2010)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1 Olsen J.V....Mann M. (2006)
- Phosphoproteomic analysis of the human pituitary. (PubMed id 16807684)1 Beranova-Giorgianni S.... Giorgianni F. (2006)
- The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)2 Dunham A.... Ross M.T. (2004)
- RFP2, c13ORF1, and FAM10A4 are the most likely tumor suppressor gene candidates for B-cell chronic lymphocytic leukemia. (PubMed id 14499696)9 van Everdink W.J.... Buys C.H. (2003)
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External Searches for ST13P4 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing ST13P4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ST13P4 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ST13P4 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ST13P4 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ST13P4 gene:
Search GeneIP for patents involving ST13P4
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ST13P4 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ST13P4 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ST13P4 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ST13P4 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ST13P4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ST13P4 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ST13P4 |
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 |  |  |  | |
| | | | Search Tocris compounds for ST13P4 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ST13P4 |
|  |  |  | | | | Search ThermoFisher Antibodies for ST13P4 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ST13P4 |
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