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Aliases for ST13P4 Gene

Aliases for ST13P4 Gene

  • ST13, Hsp70 Interacting Protein Pseudogene 4 2 3 5
  • Suppression Of Tumorigenicity 13 (Colon Carcinoma) (Hsp70 Interacting Protein) Pseudogene 4 2 3
  • Family With Sequence Similarity 10, Member A4 Pseudogene 2 3
  • FAM10A4 3 4
  • Suppression Of Tumorigenicity 13 Pseudogene 4 4
  • ST13-Like Tumor Suppressor 3
  • FAM10A4P 3

External Ids for ST13P4 Gene

Previous HGNC Symbols for ST13P4 Gene

  • FAM10A4

Previous GeneCards Identifiers for ST13P4 Gene

  • GC13P050747
  • GC13P031541

Summaries for ST13P4 Gene

GeneCards Summary for ST13P4 Gene

ST13P4 (ST13, Hsp70 Interacting Protein Pseudogene 4) is a Pseudogene.

Additional gene information for ST13P4 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ST13P4 Gene

Genomics for ST13P4 Gene

Regulatory Elements for ST13P4 Gene

Enhancers for ST13P4 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH13H050152 1 Ensembl ENCODE dbSUPER 0.4 -19.2 -19212 1.6 ZSCAN4 PRDM1 ZBTB20 RPL34P26 DLEU1 ST13P4 ENSG00000274270
GH13H050121 2 FANTOM5 Ensembl ENCODE dbSUPER 0.2 -45.3 -45262 10.1 PKNOX1 FOXA2 ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B ZNF766 ZNF143 SETDB2 KCNRG TRIM13 CTAGE10P DLEU1 RNASEH2B-AS1 ENSG00000176882 RNASEH2B EBPL DLEU2
GH13H050140 1.2 FANTOM5 Ensembl ENCODE dbSUPER 0.3 -30.4 -30418 2 ZFP69B RPL34P26 EBPL DLEU1 TRIM13 ENSG00000274270 ST13P4
GH13H050132 0.9 FANTOM5 ENCODE dbSUPER 0.3 -39.3 -39298 0.3 EZH2 RNASEH2B-AS1 RNASEH2B ENSG00000274270 ST13P4
GH13H050133 0.7 ENCODE dbSUPER 0.3 -39.8 -39809 0.1 POLR2A EZH2 RNASEH2B-AS1 RNASEH2B ENSG00000274270 ST13P4
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ST13P4 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ST13P4 Gene

Genomic Locations for ST13P4 Gene
chr13:50,172,018-50,173,616
(GRCh38/hg38)
Size:
1,599 bases
Orientation:
Plus strand
chr13:50,746,154-50,747,752
(GRCh37/hg19)

Genomic View for ST13P4 Gene

Genes around ST13P4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ST13P4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ST13P4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ST13P4 Gene

Proteins for ST13P4 Gene

  • Protein details for ST13P4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IZP2-ST134_HUMAN
    Recommended name:
    Putative protein FAM10A4
    Protein Accession:
    Q8IZP2

    Protein attributes for ST13P4 Gene

    Size:
    240 amino acids
    Molecular mass:
    27407 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ST13P4 Gene

Post-translational modifications for ST13P4 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ST13P4 Gene

Domains & Families for ST13P4 Gene

Protein Domains for ST13P4 Gene

Suggested Antigen Peptide Sequences for ST13P4 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8IZP2

UniProtKB/Swiss-Prot:

ST134_HUMAN :
  • Belongs to the FAM10 family.
Family:
  • Belongs to the FAM10 family.
genes like me logo Genes that share domains with ST13P4: view

No data available for Gene Families for ST13P4 Gene

Function for ST13P4 Gene

Gene Ontology (GO) - Molecular Function for ST13P4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0046983 protein dimerization activity IEA --
genes like me logo Genes that share ontologies with ST13P4: view
genes like me logo Genes that share phenotypes with ST13P4: view

Animal Model Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ST13P4 Gene

Localization for ST13P4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ST13P4 Gene

Cytoplasm.

Gene Ontology (GO) - Cellular Components for ST13P4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0070062 extracellular exosome IDA 20458337
genes like me logo Genes that share ontologies with ST13P4: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for ST13P4 Gene

Pathways & Interactions for ST13P4 Gene

SuperPathways for ST13P4 Gene

No Data Available

Interacting Proteins for ST13P4 Gene

Selected Interacting proteins: Q8IZP2-ST134_HUMAN for ST13P4 Gene via IID

Gene Ontology (GO) - Biological Process for ST13P4 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ST13P4 Gene

Drugs & Compounds for ST13P4 Gene

No Compound Related Data Available

Transcripts for ST13P4 Gene

mRNA/cDNA for ST13P4 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(7) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ST13P4 Gene

Suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) pseudogene 4:
Representative Sequences:

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ST13P4 Gene

No ASD Table

Relevant External Links for ST13P4 Gene

GeneLoc Exon Structure for
ST13P4
ECgene alternative splicing isoforms for
ST13P4

Expression for ST13P4 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ST13P4 Gene

NURSA nuclear receptor signaling pathways regulating expression of ST13P4 Gene:

ST13P4

SOURCE GeneReport for Unigene cluster for ST13P4 Gene:

Hs.511834

mRNA Expression by UniProt/SwissProt for ST13P4 Gene:

Q8IZP2-ST134_HUMAN
Tissue specificity: Highly expressed in bone marrow and weakly in placenta, pancreas, heart and HeLa cell line.
genes like me logo Genes that share expression patterns with ST13P4: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ST13P4 Gene

Orthologs for ST13P4 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ST13P4 Gene

Organism Taxonomy Gene Similarity Type Details
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.2123 33
Species where no ortholog for ST13P4 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ST13P4 Gene

ENSEMBL:
Gene Tree for ST13P4 (if available)
TreeFam:
Gene Tree for ST13P4 (if available)

Paralogs for ST13P4 Gene

(2) SIMAP similar genes for ST13P4 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ST13P4: view

No data available for Paralogs for ST13P4 Gene

Variants for ST13P4 Gene

Sequence variations from dbSNP and Humsavar for ST13P4 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type
rs1000232403 -- 50,170,473(+) ACTTG(C/T)CTTAT intron-variant, upstream-variant-2KB
rs1000587252 -- 50,171,120(+) ATAAT(C/T)TGGTA intron-variant, upstream-variant-2KB
rs1002983160 -- 50,173,252(+) GTCGC(A/G)ATAAT intron-variant, nc-transcript-variant
rs1002999222 -- 50,173,791(+) TTAGG(C/G)AGAAG intron-variant, downstream-variant-500B
rs1006425341 -- 50,173,860(+) TCAAT(A/G)AAGAC intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for ST13P4 Gene

Variant ID Type Subtype PubMed ID
nsv977238 CNV duplication 23825009
nsv832608 CNV gain 17160897
nsv561618 CNV loss 21841781
nsv1041501 CNV loss 25217958
nsv1035151 CNV loss 25217958
esv3580637 CNV loss 25503493
esv3580634 CNV loss 25503493

Relevant External Links for ST13P4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ST13P4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ST13P4 Gene

Disorders for ST13P4 Gene

Relevant External Links for ST13P4

Genetic Association Database (GAD)
ST13P4
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ST13P4

No disorders were found for ST13P4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ST13P4 Gene

Publications for ST13P4 Gene

  1. Multiple common variants for celiac disease influencing immune gene expression. (PMID: 20190752) Dubois PC … van Heel DA (Nature genetics 2010) 3 45 60
  2. Characterization of FAM10A4, a member of the ST13 tumor suppressor gene family that maps to the 13q14.3 region associated with B-Cell leukemia, multiple myeloma, and prostate cancer. (PMID: 12079276) Sossey-Alaoui K … Cowell JK (Genomics 2002) 3 4 60
  3. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. (PMID: 21833088) International Multiple Sclerosis Genetics Consortium … Compston A (Nature 2011) 45 60
  4. Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. (PMID: 22190364) Patsopoulos NA … de Bakker PI (Annals of neurology 2011) 45 60
  5. MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis. (PMID: 20458337) Buschow SI … Stoorvogel W (Immunology and cell biology 2010) 3 60

Products for ST13P4 Gene

Sources for ST13P4 Gene

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