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Aliases for ST13P4 Gene

Aliases for ST13P4 Gene

  • Suppression Of Tumorigenicity 13 (Colon Carcinoma) (Hsp70 Interacting Protein) Pseudogene 4 2 3
  • Family With Sequence Similarity 10, Member A4 Pseudogene 2 3
  • FAM10A4 3 4
  • Suppression Of Tumorigenicity 13 Pseudogene 4 4
  • ST13-Like Tumor Suppressor 3
  • FAM10A4P 3

External Ids for ST13P4 Gene

Previous Symbols for ST13P4 Gene

  • FAM10A4

Summaries for ST13P4 Gene

GeneCards Summary for ST13P4 Gene

ST13P4 (Suppression Of Tumorigenicity 13 (Colon Carcinoma) (Hsp70 Interacting Protein) Pseudogene 4) is a Pseudogene. Diseases associated with ST13P4 include chronic lymphocytic leukemia.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ST13P4 Gene

Genomics for ST13P4 Gene

Genomic Location for ST13P4 Gene

Start:
50,172,018 bp from pter
End:
50,173,616 bp from pter
Size:
1,599 bases
Orientation:
Plus strand

Genomic View for ST13P4 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ST13P4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ST13P4 Gene

No data available for Regulatory Elements for ST13P4 Gene

Proteins for ST13P4 Gene

  • Protein details for ST13P4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IZP2-ST134_HUMAN
    Recommended name:
    Putative protein FAM10A4
    Protein Accession:
    Q8IZP2
    Secondary Accessions:

    Protein attributes for ST13P4 Gene

    Size:
    240 amino acids
    Molecular mass:
    27407 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ST13P4 Gene

Proteomics data for ST13P4 Gene at MOPED

Post-translational modifications for ST13P4 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ST13P4 Gene

Domains for ST13P4 Gene

Protein Domains for ST13P4 Gene

UniProtKB/Swiss-Prot:

ST134_HUMAN
Family:
  • Belongs to the FAM10 family.:
    • Q8IZP2
Similarity:
  • Contains 3 TPR repeats.:
    • Q8IZP2
genes like me logo Genes that share domains with ST13P4: view

No data available for Gene Families for ST13P4 Gene

Function for ST13P4 Gene

Phenotypes for ST13P4 Gene

GenomeRNAi human phenotypes for ST13P4:
genes like me logo Genes that share phenotypes with ST13P4: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ST13P4 Gene

Localization for ST13P4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ST13P4 Gene

Cytoplasm.

Gene Ontology (GO) - Cellular Components for ST13P4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0070062 extracellular exosome IDA 20458337
genes like me logo Genes that share ontologies with ST13P4: view

Pathways for ST13P4 Gene

SuperPathways for ST13P4 Gene

No Data Available

Interacting Proteins for ST13P4 Gene

Selected Interacting proteins: Q8IZP2-ST134_HUMAN for ST13P4 Gene via MINT I2D

Symbol External ID(s) Details
MAP3K3

Gene Ontology (GO) - Biological Process for ST13P4 Gene

None

No data available for Pathways by source for ST13P4 Gene

Transcripts for ST13P4 Gene

mRNA/cDNA for ST13P4 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(7) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ST13P4 Gene

Suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) pseudogene 4:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ST13P4 Gene

No ASD Table

Relevant External Links for ST13P4 Gene

GeneLoc Exon Structure for
ST13P4
ECgene alternative splicing isoforms for
ST13P4

Expression for ST13P4 Gene

mRNA expression in normal human tissues for ST13P4 Gene

SOURCE GeneReport for Unigene cluster for ST13P4 Gene Hs.511834

mRNA Expression by UniProt/SwissProt for ST13P4 Gene

Q8IZP2-ST134_HUMAN
Tissue specificity: Highly expressed in bone marrow and weakly in placenta, pancreas, heart and HeLa cell line.
genes like me logo Genes that share expressions with ST13P4: view

Orthologs for ST13P4 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ST13P4 Gene

Organism Taxonomy Gene Similarity Type Details
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.2123 36
Species with no ortholog for ST13P4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ST13P4 Gene

ENSEMBL:
Gene Tree for ST13P4 (if available)
TreeFam:
Gene Tree for ST13P4 (if available)

Paralogs for ST13P4 Gene

Selected SIMAP similar genes for ST13P4 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ST13P4: view

No data available for Paralogs for ST13P4 Gene

Variants for ST13P4 Gene

Sequence variations from dbSNP and Humsavar for ST13P4 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type MAF
VAR_023644 -

Structural Variations from Database of Genomic Variants (DGV) for ST13P4 Gene

Variant ID Type Subtype PubMed ID
nsv832608 CNV Gain 17160897
nsv900076 CNV Loss 21882294

Relevant External Links for ST13P4 Gene

HapMap Linkage Disequilibrium report
ST13P4

Disorders for ST13P4 Gene

Relevant External Links for ST13P4

Genetic Association Database (GAD)
ST13P4
genes like me logo Genes that share disorders with ST13P4: view

No data available for UniProtKB/Swiss-Prot for ST13P4 Gene

Publications for ST13P4 Gene

  1. Multiple common variants for celiac disease influencing immune gene expression. (PMID: 20190752) Dubois P.C. … van Heel D.A. (Nat. Genet. 2010) 3 49
  2. Characterization of FAM10A4, a member of the ST13 tumor suppressor gene family that maps to the 13q14.3 region associated with B-Cell leukemia, multiple myeloma, and prostate cancer. (PMID: 12079276) Sossey-Alaoui K. … Cowell J.K. (Genomics 2002) 3 4
  3. Phosphoproteomic analysis of the human pituitary. (PMID: 16807684) Beranova-Giorgianni S. … Giorgianni F. (Pituitary 2006) 3
  4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3
  5. RFP2, c13ORF1, and FAM10A4 are the most likely tumor suppressor gene candidates for B-cell chronic lymphocytic leukemia. (PMID: 14499696) van Everdink W.J. … Buys C.H. (Cancer Genet. Cytogenet. 2003) 23

Products for ST13P4 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate ST13P4
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ST13P4
    • Block miRNA regulation of ST13P4 using miScript Target Protectors

    Sources for ST13P4 Gene

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