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Aliases for SSX9 Gene

Aliases for SSX9 Gene

  • SSX Family Member 9, Pseudogene 2 3 5
  • Synovial Sarcoma, X Breakpoint 9 2 3
  • SSX Family Member 9 2 3
  • Synovial Sarcoma, X Breakpoint 7, Pseudogene 3
  • SSX9P 3

External Ids for SSX9 Gene

Previous GeneCards Identifiers for SSX9 Gene

  • GC0XU900003
  • GC0XM046981
  • GC0XM047201
  • GC0XM047202
  • GC0XM047911
  • GC0XM048039
  • GC0XM048154

Summaries for SSX9 Gene

Entrez Gene Summary for SSX9 Gene

  • The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. [provided by RefSeq, Jul 2008]

GeneCards Summary for SSX9 Gene

SSX9 (SSX Family Member 9, Pseudogene) is a Pseudogene. GO annotations related to this gene include nucleic acid binding.

UniProtKB/Swiss-Prot for SSX9 Gene

  • Could act as a modulator of transcription.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SSX9 Gene

Genomics for SSX9 Gene

Regulatory Elements for SSX9 Gene

Enhancers for SSX9 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XF048589 1.4 Ensembl ENCODE 16.2 -285.1 -285052 3.1 ELF3 ARNT CREB3L1 RAD21 ZNF2 ZNF366 SCRT2 FOS YY2 USF2 ENSG00000204620 ENSG00000270747 SSXP9 SSX9 GAGE12G GAGE2A GAGE12C GAGE12J GAGE12H ENSG00000270012
GH0XF048910 0.2 ENCODE 16.2 -606.0 -605994 4.0 PKNOX1 ATF1 CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF121 ELK1 GAGE12J SSXP9 ENSG00000270747 GAGE12G GAGE2A SSX9 PAGE1 GAGE12C GAGE12H ENSG00000204620
GH0XF049037 1.1 ENCODE 16.2 -735.0 -734953 7.0 HDGF PKNOX1 ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 ZNF766 GAGE12J GAGE12C GAGE12G GAGE12H GAGE2A SSXP9 PAGE1 ENSG00000270747 SSX9 PRAF2
GH0XF049052 0.5 ENCODE 16.2 -747.8 -747827 2.2 PKNOX1 ARNT CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 FOS CEBPZ ENSG00000204620 GAGE12J GAGE12C GAGE12G GAGE12H GAGE2A PAGE1 ENSG00000270747 SSX9 SSXP9
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around SSX9 on UCSC Golden Path with GeneCards custom track

Genomic Location for SSX9 Gene

Chromosome:
X
Start:
48,296,816 bp from pter
End:
48,306,179 bp from pter
Size:
9,364 bases
Orientation:
Minus strand

Genomic View for SSX9 Gene

Genes around SSX9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SSX9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SSX9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SSX9 Gene

Proteins for SSX9 Gene

  • Protein details for SSX9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7RTT3-SSX9_HUMAN
    Recommended name:
    Protein SSX9
    Protein Accession:
    Q7RTT3

    Protein attributes for SSX9 Gene

    Size:
    188 amino acids
    Molecular mass:
    21553 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SSX9 Gene

Post-translational modifications for SSX9 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for SSX9 Gene

Domains & Families for SSX9 Gene

Protein Domains for SSX9 Gene

Suggested Antigen Peptide Sequences for SSX9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q7RTT3

UniProtKB/Swiss-Prot:

SSX9_HUMAN :
  • Contains 1 KRAB-related domain.
  • Belongs to the SSX family.
Domain:
  • Contains 1 KRAB-related domain.
Family:
  • Belongs to the SSX family.
genes like me logo Genes that share domains with SSX9: view

No data available for Gene Families for SSX9 Gene

Function for SSX9 Gene

Molecular function for SSX9 Gene

UniProtKB/Swiss-Prot Function:
Could act as a modulator of transcription.

Gene Ontology (GO) - Molecular Function for SSX9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003714 transcription corepressor activity IBA --
genes like me logo Genes that share ontologies with SSX9: view

Phenotypes for SSX9 Gene

GenomeRNAi human phenotypes for SSX9:
genes like me logo Genes that share phenotypes with SSX9: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SSX9 Gene

Localization for SSX9 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SSX9 Gene COMPARTMENTS Subcellular localization image for SSX9 gene
Compartment Confidence
nucleus 5
cytosol 2
golgi apparatus 1
mitochondrion 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for SSX9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with SSX9: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for SSX9 Gene

Pathways & Interactions for SSX9 Gene

SuperPathways for SSX9 Gene

No Data Available

Interacting Proteins for SSX9 Gene

Gene Ontology (GO) - Biological Process for SSX9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:1903507 negative regulation of nucleic acid-templated transcription IBA --
genes like me logo Genes that share ontologies with SSX9: view

No data available for Pathways by source and SIGNOR curated interactions for SSX9 Gene

Transcripts for SSX9 Gene

mRNA/cDNA for SSX9 Gene

(1) REFSEQ mRNAs :
(2) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SSX9 Gene

No ASD Table

Relevant External Links for SSX9 Gene

GeneLoc Exon Structure for
SSX9
ECgene alternative splicing isoforms for
SSX9

Expression for SSX9 Gene

mRNA expression in normal human tissues for SSX9 Gene

mRNA differential expression in normal tissues according to GTEx for SSX9 Gene

This gene is overexpressed in Testis (x53.0).

NURSA nuclear receptor signaling pathways regulating expression of SSX9 Gene:

SSX9

mRNA Expression by UniProt/SwissProt for SSX9 Gene:

Q7RTT3-SSX9_HUMAN
Tissue specificity: Not detected in any normal or tumor tissues.
genes like me logo Genes that share expression patterns with SSX9: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for SSX9 Gene

Orthologs for SSX9 Gene

Evolution for SSX9 Gene

ENSEMBL:
Gene Tree for SSX9 (if available)
TreeFam:
Gene Tree for SSX9 (if available)

No data available for Orthologs for SSX9 Gene

Paralogs for SSX9 Gene

(17) SIMAP similar genes for SSX9 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SSX9: view

No data available for Paralogs for SSX9 Gene

Variants for SSX9 Gene

Sequence variations from dbSNP and Humsavar for SSX9 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs10669972 -- 48,307,274(+) CCTAT(-/TT)TTTTT upstream-variant-2KB
rs111877810 -- 48,304,021(+) GCAGG(A/G)TCCAG intron-variant
rs111957618 -- 48,305,629(+) AACAA(-/C)AAAAC intron-variant
rs112410387 -- 48,301,420(+) CTCGT(G/T)ATTAT downstream-variant-500B
rs112513685 -- 48,304,125(+) ACAAA(A/C)GGAAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SSX9 Gene

Variant ID Type Subtype PubMed ID
esv25781 CNV gain 19812545
esv2671998 CNV deletion 23128226
esv2740147 CNV deletion 23290073
esv2752324 CNV gain 17911159
esv32909 CNV gain+loss 17666407
esv3573943 CNV loss 25503493
nsv523595 CNV gain 19592680

Relevant External Links for SSX9 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SSX9

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SSX9 Gene

Disorders for SSX9 Gene

Relevant External Links for SSX9

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SSX9

No disorders were found for SSX9 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SSX9 Gene

Publications for SSX9 Gene

  1. The SSX gene family: characterization of 9 complete genes. (PMID: 12216073) Gure A.O. … Chen Y.-T. (Int. J. Cancer 2002) 2 3 4 64
  2. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4 64
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for SSX9 Gene

Sources for SSX9 Gene

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