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Aliases for SSX8 Gene

Aliases for SSX8 Gene

  • Synovial Sarcoma, X Breakpoint 8 2 3

External Ids for SSX8 Gene

Previous GeneCards Identifiers for SSX8 Gene

  • GC0XM050364
  • GC0XP051305
  • GC0XP051618
  • GC0XP052535
  • GC0XP052668
  • GC0XP052670
  • GC0XP049780

Summaries for SSX8 Gene

GeneCards Summary for SSX8 Gene

SSX8 (Synovial Sarcoma, X Breakpoint 8) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding.

UniProtKB/Swiss-Prot for SSX8 Gene

  • Could act as a modulator of transcription

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SSX8 Gene

Genomics for SSX8 Gene

Regulatory Elements for SSX8 Gene

Genomic Location for SSX8 Gene

Chromosome:
X
Start:
52,622,935 bp from pter
End:
52,633,948 bp from pter
Size:
11,014 bases
Orientation:
Plus strand

Genomic View for SSX8 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for SSX8 Gene

Proteins for SSX8 Gene

  • Protein details for SSX8 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7RTT4-SSX8_HUMAN
    Recommended name:
    Protein SSX8
    Protein Accession:
    Q7RTT4
    Secondary Accessions:
    • A6NJM6

    Protein attributes for SSX8 Gene

    Size:
    187 amino acids
    Molecular mass:
    21859 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=DAA00375.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for SSX8 Gene

Proteomics data for SSX8 Gene at MOPED

Post-translational modifications for SSX8 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SSX8 Gene

Domains & Families for SSX8 Gene

Protein Domains for SSX8 Gene

Suggested Antigen Peptide Sequences for SSX8 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q7RTT4

UniProtKB/Swiss-Prot:

SSX8_HUMAN :
  • Contains 1 KRAB-related domain.
  • Belongs to the SSX family.
Domain:
  • Contains 1 KRAB-related domain.
Family:
  • Belongs to the SSX family.
genes like me logo Genes that share domains with SSX8: view

No data available for Gene Families for SSX8 Gene

Function for SSX8 Gene

Molecular function for SSX8 Gene

UniProtKB/Swiss-Prot Function:
Could act as a modulator of transcription

Gene Ontology (GO) - Molecular Function for SSX8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003714 transcription corepressor activity IBA --
genes like me logo Genes that share ontologies with SSX8: view

Phenotypes for SSX8 Gene

GenomeRNAi human phenotypes for SSX8:
genes like me logo Genes that share phenotypes with SSX8: view

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SSX8

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SSX8 Gene

Localization for SSX8 Gene

Gene Ontology (GO) - Cellular Components for SSX8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with SSX8: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for SSX8 Gene

Pathways & Interactions for SSX8 Gene

SuperPathways for SSX8 Gene

No Data Available

Interacting Proteins for SSX8 Gene

Gene Ontology (GO) - Biological Process for SSX8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:1903507 negative regulation of nucleic acid-templated transcription IBA --
genes like me logo Genes that share ontologies with SSX8: view

No data available for Pathways by source and SIGNOR curated interactions for SSX8 Gene

Drugs & Compounds for SSX8 Gene

No Compound Related Data Available

Transcripts for SSX8 Gene

mRNA/cDNA for SSX8 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SSX8 Gene

Synovial sarcoma, X breakpoint 8:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SSX8

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SSX8 Gene

No ASD Table

Relevant External Links for SSX8 Gene

GeneLoc Exon Structure for
SSX8
ECgene alternative splicing isoforms for
SSX8

Expression for SSX8 Gene

mRNA expression in normal human tissues for SSX8 Gene

mRNA differential expression in normal tissues according to GTEx for SSX8 Gene

This gene is overexpressed in Testis (x49.4).

SOURCE GeneReport for Unigene cluster for SSX8 Gene Hs.694472

mRNA Expression by UniProt/SwissProt for SSX8 Gene

Q7RTT4-SSX8_HUMAN
Tissue specificity: Not detected in any normal or tumor tissues.
genes like me logo Genes that share expression patterns with SSX8: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for SSX8 Gene

Orthologs for SSX8 Gene

Evolution for SSX8 Gene

ENSEMBL:
Gene Tree for SSX8 (if available)
TreeFam:
Gene Tree for SSX8 (if available)

No data available for Orthologs for SSX8 Gene

Paralogs for SSX8 Gene

(18) SIMAP similar genes for SSX8 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SSX8: view

No data available for Paralogs for SSX8 Gene

Variants for SSX8 Gene

Sequence variations from dbSNP and Humsavar for SSX8 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs4893635 -- 52,631,981(+) agagt(C/T)gggaa intron-variant
rs5986176 -- 52,626,859(+) TGCCT(A/C)CCGGG intron-variant
rs7057498 -- 52,634,038(+) aattg(A/C)tgtgt downstream-variant-500B
rs34543558 -- 52,626,539(-) TGAAT(A/G)GCCTC intron-variant
rs35573383 -- 52,626,579(-) TGAAA(A/G)TACAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SSX8 Gene

Variant ID Type Subtype PubMed ID
esv2740170 CNV Deletion 23290073
esv21492 CNV Gain 19812545

Relevant External Links for SSX8 Gene

HapMap Linkage Disequilibrium report
SSX8

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SSX8 Gene

Disorders for SSX8 Gene

Relevant External Links for SSX8

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SSX8
genes like me logo Genes that share disorders with SSX8: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SSX8 Gene

Publications for SSX8 Gene

  1. The SSX gene family: characterization of 9 complete genes. (PMID: 12216073) Gure A.O. … Chen Y.-T. (Int. J. Cancer 2002) 2 67
  2. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 67

Products for SSX8 Gene

Sources for SSX8 Gene

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