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Aliases for SSX7 Gene

Aliases for SSX7 Gene

  • Synovial Sarcoma, X Breakpoint 7 2 3

External Ids for SSX7 Gene

Summaries for SSX7 Gene

Entrez Gene Summary for SSX7 Gene

  • The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. [provided by RefSeq, Jul 2008]

GeneCards Summary for SSX7 Gene

SSX7 (Synovial Sarcoma, X Breakpoint 7) is a Protein Coding gene. Diseases associated with SSX7 include sarcoma. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is SSX3.

UniProtKB/Swiss-Prot for SSX7 Gene

  • Could act as a modulator of transcription

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SSX7 Gene

Genomics for SSX7 Gene

Genomic Location for SSX7 Gene

Start:
52,644,061 bp from pter
End:
52,654,900 bp from pter
Size:
10,840 bases
Orientation:
Minus strand

Genomic View for SSX7 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SSX7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SSX7 Gene

Proteins for SSX7 Gene

  • Protein details for SSX7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7RTT5-SSX7_HUMAN
    Recommended name:
    Protein SSX7
    Protein Accession:
    Q7RTT5
    Secondary Accessions:

    Protein attributes for SSX7 Gene

    Size:
    188 amino acids
    Molecular mass:
    21591 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SSX7 Gene

Proteomics data for SSX7 Gene at MOPED

Post-translational modifications for SSX7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SSX7 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SSX7 Gene

Domains for SSX7 Gene

Protein Domains for SSX7 Gene

UniProtKB/Swiss-Prot:

SSX7_HUMAN
Domain:
  • Contains 1 KRAB-related domain.:
    • Q7RTT5
Family:
  • Belongs to the SSX family.:
    • Q7RTT5
genes like me logo Genes that share domains with SSX7: view

No data available for Gene Families for SSX7 Gene

Function for SSX7 Gene

Molecular function for SSX7 Gene

UniProtKB/Swiss-Prot Function: Could act as a modulator of transcription

Gene Ontology (GO) - Molecular Function for SSX7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
genes like me logo Genes that share ontologies with SSX7: view

Phenotypes for SSX7 Gene

genes like me logo Genes that share phenotypes with SSX7: view

miRNA for SSX7 Gene

miRTarBase miRNAs that target SSX7

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for SSX7 Gene

Localization for SSX7 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SSX7 Gene COMPARTMENTS Subcellular localization image for SSX7 gene
Compartment Confidence
nucleus 3
cytosol 2
mitochondrion 1

Gene Ontology (GO) - Cellular Components for SSX7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with SSX7: view

Pathways for SSX7 Gene

SuperPathways for SSX7 Gene

No Data Available

Interacting Proteins for SSX7 Gene

Selected Interacting proteins: Q7RTT5-SSX7_HUMAN for SSX7 Gene via I2D

Symbol External ID(s) Details
SNAI2

Gene Ontology (GO) - Biological Process for SSX7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with SSX7: view

No data available for Pathways by source for SSX7 Gene

Transcripts for SSX7 Gene

mRNA/cDNA for SSX7 Gene

(1) REFSEQ mRNAs :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SSX7 Gene

No ASD Table

Relevant External Links for SSX7 Gene

GeneLoc Exon Structure for
SSX7
ECgene alternative splicing isoforms for
SSX7

Expression for SSX7 Gene

mRNA expression in normal human tissues for SSX7 Gene

SOURCE GeneReport for Unigene cluster for SSX7 Gene Hs.558712

mRNA Expression by UniProt/SwissProt for SSX7 Gene

Q7RTT5-SSX7_HUMAN
Tissue specificity: Testis-specific. Expressed in a melanoma cell line.
genes like me logo Genes that share expressions with SSX7: view

Orthologs for SSX7 Gene

This gene was present in the common ancestor of mammals.

Orthologs for SSX7 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SSX7 37
  • 91 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SSX5 37
  • 30 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 37
  • 48 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Gm14459 37
  • 30 (a)
ManyToMany
Gm21876 37
  • 40 (a)
ManyToMany
Gm5751 37
  • 33 (a)
ManyToMany
Gm6592 37
  • 31 (a)
ManyToMany
Ssx9 37
  • 31 (a)
ManyToMany
Ssxa1 37
  • 43 (a)
ManyToMany
Ssxb1 37
  • 32 (a)
ManyToMany
Ssxb10 37
  • 32 (a)
ManyToMany
Ssxb2 37
  • 30 (a)
ManyToMany
Ssxb3 37
  • 32 (a)
ManyToMany
Ssxb5 37
  • 33 (a)
ManyToMany
Ssxb6 37
  • 27 (a)
ManyToMany
Ssxb8 37
  • 33 (a)
ManyToMany
Ssxb9 37
  • 31 (a)
ManyToMany
Species with no ortholog for SSX7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SSX7 Gene

ENSEMBL:
Gene Tree for SSX7 (if available)
TreeFam:
Gene Tree for SSX7 (if available)

Paralogs for SSX7 Gene

Paralogs for SSX7 Gene

Selected SIMAP similar genes for SSX7 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SSX7: view

Variants for SSX7 Gene

Sequence variations from dbSNP and Humsavar for SSX7 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs2492317 -- 52,644,636(-) AGAAG(C/T)AGAAC utr-variant-3-prime
rs2492318 -- 52,643,673(-) acagg(A/C)atgca downstream-variant-500B
rs2492319 -- 52,643,650(-) actaa(G/T)ttttt downstream-variant-500B
rs2811831 -- 52,644,724(-) GAGTT(A/G)TCACG intron-variant
rs2999121 -- 52,645,235(+) tgctg(C/T)actgc intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for SSX7 Gene

Variant ID Type Subtype PubMed ID
esv2740170 CNV Deletion 23290073
esv21492 CNV Gain 19812545

Relevant External Links for SSX7 Gene

HapMap Linkage Disequilibrium report
SSX7
Human Gene Mutation Database (HGMD)
SSX7

Disorders for SSX7 Gene

(1) MalaCards Diseases for SSX7 Gene

Search for SSX7 Gene in MalaCards »
genes like me logo Genes that share disorders with SSX7: view

No data available for UniProtKB/Swiss-Prot for SSX7 Gene

Publications for SSX7 Gene

  1. The SSX gene family: characterization of 9 complete genes. (PMID: 12216073) Gure A.O. … Chen Y.-T. (Int. J. Cancer 2002) 2 3 4 23
  2. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  3. Expressions of cancer-testis antigens in human hepatocellular carcinomas. (PMID: 11179834) Chen C.H. … Sheu J.C. (Cancer Lett. 2001) 3

Products for SSX7 Gene

Sources for SSX7 Gene

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