External Ids for SSX5 Gene
Previous GeneCards Identifiers for SSX5 Gene
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. While some of the related SSX genes are involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas, this gene does not appear to be involved in such translocations. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2013]
GeneCards Summary for SSX5 Gene
SSX5 (Synovial Sarcoma, X Breakpoint 5) is a Protein Coding gene. Diseases associated with SSX5 include sarcoma. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is SSX3.
UniProtKB/Swiss-Prot for SSX5 Gene
Could act as a modulator of transcription