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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SSX4 Gene

protein-coding   GIFtS: 46
GCID: GC0XP048242

Synovial Sarcoma, X Breakpoint 4

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Synovial Sarcoma, X Breakpoint 41 2
Cancer/Testis Antigen 5.42 3
CT5.42 3
Protein SSX42
SSX4A3

External Ids:    HGNC: 113381   Entrez Gene: 67592   Ensembl: ENSG000002046457   OMIM: 3003265   UniProtKB: O602243   

Export aliases for SSX4 gene to outside databases

Previous GC identifers: GC0XM047064 GC0XM046522 GC0XP047069 GC0XP047288 GC0XM048017 GC0XP048127


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SSX4 Gene:
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins.
These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously
humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer
vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation
characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial
sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a
segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in
tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding
distinct isoforms have been identified for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for SSX4 Gene: 
SSX4 (synovial sarcoma, X breakpoint 4) is a protein-coding gene. Diseases associated with SSX4 include synovial sarcoma, and sarcoma. An important paralog of this gene is SSX2B.

UniProtKB/Swiss-Prot: SSX4_HUMAN, O60224
Function: Could act as a modulator of transcription

Gene Wiki entry for SSX4 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SSX4 gene promoter:
         NCX/Ncx   HNF-1A   C/EBPalpha   POU2F1   HNF-1   POU2F1a   Sox9   POU2F1c   RSRFC4   En-1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for SSX4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SSX4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp11.23   Ensembl cytogenetic band:  Xp11.23   HGNC cytogenetic band: Xp11.23

SSX4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SSX4 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP048242:  view genomic region     (about GC identifiers)

Start:
48,242,863 bp from pter      End:
48,252,785 bp from pter
Size:
9,923 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SSX4_HUMAN, O60224 (See protein sequence)
Recommended Name: Protein SSX4  
Size: 188 amino acids; 21858 Da
Secondary accessions: B2RPE3 Q5JQZ0 Q9UJU9

Explore the universe of human proteins at neXtProt for SSX4: NX_O60224

Explore proteomics data for SSX4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O60224

  • SSX4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SSX4 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_005627.1  NP_783856.1  

    ENSEMBL proteins: 
     ENSP00000366083   ENSP00000364667  

    Human Recombinant Protein Products for SSX4: 
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    GenScript Custom Purified and Recombinant Proteins Services for SSX4
    Novus Biologicals SSX4 Proteins
    Novus Biologicals SSX4 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SSX4 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus ----

    SSX4 for ontologies           About GeneDecksing



    SSX4 Antibody Products: 
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    LSBio Antibodies in human, mouse, rat for SSX4 

    Assay Products for SSX4: 
    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for SSX4 
    Cloud-Clone Corp. CLIAs for SSX4


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR003655 Krueppel-associated_box-rel
     IPR019041 SSXRD_motif
     IPR001909 Krueppel-associated_box

    Graphical View of Domain Structure for InterPro Entry O60224

    ProtoNet protein and cluster: O60224

    1 Blocks protein domain: IPB001909 KRAB box

    UniProtKB/Swiss-Prot: SSX4_HUMAN, O60224
    Similarity: Belongs to the SSX family
    Similarity: Contains 1 KRAB-related domain


    SSX4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SSX4_HUMAN, O60224
    Function: Could act as a modulator of transcription

         Genatlas biochemistry entry for SSX4:
    protein SSX4 with homology to Kruppel associated box,KRAB,not implicated in t(X;18) synovial sarcoma

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
         
    SSX4 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SSX4 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SSX4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SSX4 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SSX4 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SSX4
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate SSX4:
    hsa-miR-222* hsa-miR-199b-3p hsa-miR-199a-3p hsa-miR-3129-5p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SSX4
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    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of SSX4

    Clone
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    OriGene clones in human, mouse for SSX4 (see all 10)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): SSX4 (NM_005636)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SSX4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SSX4
    Sirion Biotech Customized lentivirus for stable overexpression of SSX4 
                         Customized lentivirus expression plasmids for stable overexpression of SSX4 

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    Search LifeMap BioReagents cell lines for SSX4
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SSX4


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SSX4

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for SSX4 (O602242, 3 ENSP000003660834) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIF1AQ166652, 3, ENSP000003380184MINT-66671 I2D: score=5 STRING: ENSP00000338018
    PAX9P557713, ENSP000003552454I2D: score=1 STRING: ENSP00000355245
    XBP1P178613, ENSP000002160374I2D: score=1 STRING: ENSP00000216037
    LZTR1Q8N6533, ENSP000002157394I2D: score=1 STRING: ENSP00000215739
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent ----
    GO:0006355regulation of transcription, DNA-dependent ----

    SSX4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SSX4

    Search CenterWatch for drugs/clinical trials and news about SSX4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SSX4 gene (2 alternative transcripts): 
    NM_005636.3  NM_175729.1  

    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000376886(uc004djf.1 uc004djg.1) ENST00000375517
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SSX4
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate SSX4:
    hsa-miR-222* hsa-miR-199b-3p hsa-miR-199a-3p hsa-miR-3129-5p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SSX4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SSX4
    Clone
    Products:
         
    OriGene clones in human, mouse for SSX4 (see all 10)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): SSX4 (NM_005636)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SSX4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SSX4
    Sirion Biotech Customized lentivirus for stable overexpression of SSX4 
                         Customized lentivirus expression plasmids for stable overexpression of SSX4 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for SSX4
    OriGene qSTAR qPCR primer pairs in human, mouse for SSX4
    Search SABiosciences RT2 qPCR Primer Assays in human, mouse, rat SSX4
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SSX4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SSX4

    16 AceView cDNA sequences:

    AA312651 BX279816 BU632654 BX102714 U90841 NM_005636 CD671169 NM_175729 
    CD671168 BC005325 BE866727 AI699644 H99655 N72228 W00507 N24445 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SSX4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SSX4 Expression
    About this image


    See SSX4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SSX4
        SABiosciences Custom PCR Arrays for SSX4
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for SSX4
    OriGene qSTAR qPCR primer pairs in human, mouse for SSX4
    Search SABiosciences RT2 qPCR Primer Assays in human, mouse, rat SSX4
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SSX4
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SSX4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SSX4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
      --

    ENSEMBL Gene Tree for SSX4 (if available)
    TreeFam Gene Tree for SSX4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SSX4 gene
    SSX4B1 2  SSX2B2  SSX22  SSX62  SSX72  SSX12  SSX52  SSX92  
    SSX32  
    14 SIMAP similar genes for SSX4 using alignment to 2 protein entries:     SSX4_HUMAN (see all proteins):
    SSX4B    SSX6    SSX3    SSX9    SSX11    SSX1
    SSX7    SSX5    SSX2B    SSX2    SSX8    SYT-SSX2
    SSX10    SYT-SSX1

    SSX4 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SSX4
    PGOHUM00000241751


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/30 SNPs in SSX4 are shown (see all 30)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1808322651,2
    C--48241285(+) GAGGCC/TGAGGC 2 -- us2k10--------
    rs2008716731,2
    --48241361(+) CTAAT-/AAGAAGAA 2 -- us2k10--------
    rs2002671241,2
    C--48243015(+) GCATGC/TGCTGA 2 -- int10--------
    rs2013327121,2
    C--48244036(+) CTAAGA/GAAGAG 4 K E mis10--------
    rs1407484171,2
    C,F--48244866(+) TGGTAA/GCGATC 4 N S mis11Minor allele frequency- G:0.00NA 2280
    rs1860666291,2
    --48244994(+) ACATCA/GGGGCT 2 -- int10--------
    rs2005956761,2
    ----48244072(+) AAATCG/TTCTAT 4 V F mis10--------
    rs3742628311,2
    ----48248392(+) GTTTTC/TCATTT 2 -- int10--------
    rs3727281211,2
    ----48244261(+) GTTCTC/GTCTTC 2 -- int10--------
    rs2008611701,2
    ----48244000(+) TTTTCC/TAGGCC 2 -- int10--------

    HapMap Linkage Disequilibrium report for SSX4 (48242863 - 48252785 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for SSX4:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2671998CNV Deletion23128226
    esv25781CNV Gain19812545
    esv32909CNV Gain+Loss17666407
    nsv7441OTHER Inversion18451855

    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing SSX4
    DNA2.0 Custom Variant and Variant Library Synthesis for SSX4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 300326    OMIM disorders: --

    5 diseases for SSX4:    About MalaCards
    synovial sarcoma    sarcoma    lung cancer    melanoma
    hepatocellular carcinoma

    1 disease from the University of Copenhagen DISEASES database for SSX4:
    Synovial sarcoma

    SSX4 for disorders           About GeneDecksing

    4 Novoseek inferred disease relationships for SSX4 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    sarcoma synovial 88.4 3 18519690 (1), 12007189 (1), 11308259 (1)
    melanoma 31.7 3 12007189 (1), 10749136 (1), 9378559 (1)
    tumors 18.8 1 16299236 (1)
    cancer 6.93 5 15603546 (2), 10749136 (1)


    Export disorders for SSX4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SSX4 gene, integrated from 9 sources (see all 23):
    (articles sorted by number of sources associating them with SSX4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. SSX: a multigene family with several members transcribed in normal testis and human cancer. (PubMed id 9378559)1, 2, 9 Gure A.O....Chen Y.T. (1997)
    2. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP. (PubMed id 12007189)1, 9 de Bruijn D.R.H....van Kessel A.G. (2002)
    5. Cloning and characterization of spliced fusion transcript variants of synovial sarcoma: SYT/SSX4, SYT/SSX4v, and SYT/SSX2v. Possible regulatory role of the fusion gene product in wild type SYT expression. (PubMed id 11368913)1, 9 Brodin B.... Larsson O. (2001)
    6. Clinical impact of molecular and cytogenetic findings in synovial sarcoma. (PubMed id 11433527)1, 9 Panagopoulos I....Mandahl N. (2001)
    7. Identification and functional characterization of gli oma-specific promoters and their application in suicide gene therapy. (PubMed id 21347689)1 Yawata T....Shimizu K. (2011)
    8. An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (2010)
    9. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
    10. CD4+ T cell responses to SSX-4 in melanoma patients. (PubMed id 15814740)1 Ayyoub M....Valmori D. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6759 HGNC: 11338 AceView: SSX4.1 Ensembl:ENSG00000204645 euGenes: HUgn6759
    ECgene: SSX4 H-InvDB: SSX4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SSX4 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for SSX4 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SSX4 gene:
    Search GeneIP for patents involving SSX4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
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     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for SSX4  
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     OriGene Custom Antibody Services for SSX4   OriGene Custom Protein Services for SSX4  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SSX4
     QIAGEN SeqTarget long-range PCR primers for resequencing SSX4
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SSX4
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SSX4
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     GenScript Custom Purified and Recombinant Proteins Services for SSX4 GenScript cDNA clones with any tag delivered in your preferred vector for SSX4
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     Search for Antibodies & Assays

     Regulatory tfbs in SSX4 promoter
     Search Chromatin IP Primers for SSX4
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     Browse Sino Biological Proteins and Antibodies
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     Novus Tissue Slides
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     Browse ProSpec Recombinant Proteins




     Proteins for SSX4
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     Search ThermoFisher Antibodies for SSX4
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SSX4
     inGenious Targeting Laboratory - Custom generated mouse model solutions for SSX4
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SSX4
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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