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SSX3 Gene

protein-coding GIFtS: 49
GCID: GC0XM048205

Synovial Sarcoma, X Breakpoint 3

See SSX3-related diseases
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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Aliases
Synovial Sarcoma, X Breakpoint 3¹ ²
Cancer/Testis Antigen 5.3² ³
CT5.3² ³
Kruppel-Associated Box Containing Gene Product SSX3²
Protein SSX3²

External Ids:	HGNC: 11337¹	Entrez Gene: 10214²	Ensembl: ENSG00000165584⁷	OMIM: 300325⁵	UniProtKB: Q99909³

Export aliases for SSX3 gene to outside databases

Previous GC identifers: GC0XM047008 GC0XM046466 GC0XM047200 GC0XM047251 GC0XM047962 GC0XM048090 GC0XM045914

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SSX3 Gene:

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins.

These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral

and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based

immunotherapy. While some of the related SSX genes are involved in t(X;18)(p11.2;q11.2) translocations that are

characteristically found in all synovial sarcomas, this gene does not appear to be involved in such

translocations. (provided by RefSeq, Jul 2013)

GeneCards Summary for SSX3 Gene:

SSX3 (synovial sarcoma, X breakpoint 3) is a protein-coding gene. Diseases associated with SSX3 include synovial sarcoma, and sarcoma. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is SSX5.

UniProtKB/Swiss-Prot: SSX3_HUMAN, Q99909

Function: Could act as a modulator of transcription

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:

NC_000023.10 NT_079573.5 NC_018934.2

Regulatory elements:

Regulatory transcription factor binding sites in the SSX3 gene promoter:
C/EBPbeta HNF-1A C/EBPalpha POU2F1 HNF-1 POU2F1a POU2F1b Sox9 POU2F1c
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SSX3 promoter sequence

Search Chromatin IP Primers for SSX3

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SSX3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp11.23 Ensembl cytogenetic band: Xp11.23 HGNC cytogenetic band: Xp11.23

SSX3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SSX3 gene location

GeneLoc information about chromosome X GeneLoc Exon Structure

GeneLoc location for GC0XM048205: view genomic region (about GC identifiers)

Start:	48,205,863 bp from pter	End:	48,216,142 bp from pter
Size:	10,280 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: SSX3_HUMAN, Q99909 (See protein sequence)

Recommended Name: Protein SSX3

Size: 188 amino acids; 21697 Da

Subunit: Interacts with SSX2IP

Secondary accessions: O60223 Q5JQZ3 Q9BRW7

Alternative splicing: 2 isoforms: Q99909-1 Q99909-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SSX3: NX_Q99909

Explore proteomics data for SSX3 at MOPED

Post-translational modifications:

Modification sites at neXtProt

Modification sites at PhosphoSitePlus

See SSX3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_066294.1

ENSEMBL proteins:

ENSP00000298396 ENSP00000366092 ENSP00000366090

SSX3 Human Recombinant Protein Products:

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	Novus Biologicals SSX3 Proteins Novus Biologicals SSX3 Lysates
	Browse Sino Biological Recombinant Proteins Browse Sino Biological Cell Lysates
	Browse ProSpec Recombinant Proteins
	Cloud-Clone Corp. Proteins for SSX3
	Search eBioscience for Proteins for SSX3
	antibodies-online proteins for SSX3 (5 products)
	antibodies-online peptides for SSX3

SSX3 Antibody Products:

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	Novus Biologicals SSX3 Antibodies
	Abcam antibodies for SSX3
	Cloud-Clone Corp. Antibodies for SSX3
	Search ThermoFisher Antibodies for SSX3
	antibodies-online antibodies for SSX3 (16 products)

SSX3 Assay Products:

	Browse Kits and Assays available from EMD Millipore
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	Browse Enzo Life Sciences for kits & assays
	Cloud-Clone Corp. ELISAs for SSX3 Cloud-Clone Corp. CLIAs for SSX3
	Search eBioscience for ELISAs for SSX3
	antibodies-online kits for SSX3 (2 products)

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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4 InterPro protein domains:

IPR003655 Krueppel-associated_box-rel

IPR019041 SSXRD_motif

IPR028804 SSX

IPR001909 Krueppel-associated_box

Graphical View of Domain Structure for InterPro Entry Q99909

ProtoNet protein and cluster: Q99909

1 Blocks protein domain: IPB001909 KRAB box

UniProtKB/Swiss-Prot: SSX3_HUMAN, Q99909

Similarity: Belongs to the SSX family

Similarity: Contains 1 KRAB-related domain

Find genes that share domains with SSX3 About GenesLikeMe

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

UniProtKB/Swiss-Prot Summary: SSX3_HUMAN, Q99909

Function: Could act as a modulator of transcription

Genatlas biochemistry entry for SSX3:

protein SSX3 with homology to Kruppel associated box,KRAB,not implicated in t(X;18) synovial sarcoma

Gene Ontology (GO): 1 molecular function term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003676	nucleic acid binding	IEA	--

Find genes that share ontologies with SSX3 About GenesLikeMe

Animal Models:

genOway: Develop your customized and physiologically relevant rodent model for SSX3

miRNA Products:		Block miRNA regulation of human, mouse, rat SSX3 using miScript Target Protectors
		3 qRT-PCR Assays for microRNAs that regulate SSX3:
		hsa-miR-199b-3p hsa-miR-199a-3p hsa-miR-3129-5p
		SwitchGear 3'UTR luciferase reporter plasmid: SSX3 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for SSX3
		Predesigned siRNA for gene silencing in human, mouse, rat SSX3

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for SSX3

Clone Products:		OriGene clones in human, mouse for SSX3 (see all 9) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): SSX3 (NM_021014)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SSX3
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SSX3

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for SSX3
		Browse ESI BIO Cell Lines and PureStem Progenitors for SSX3

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SSX3

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from COMPARTMENTS:

Compartment	Confidence
cytosol	3
nucleus	3
extracellular	1

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Gene Ontology (GO): 2 cellular component terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	--	--
GO:0005634	nucleus	IEA	--

Find genes that share ontologies with SSX3 About GenesLikeMe

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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Custom Pathway & Disease-focused RT² Profiler PCR Arrays for SSX3
Interactions:

GeneGlobe Interaction Network for SSX3

STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

Selected Interacting proteins for SSX3 (Q99909³ ENSP00000298396⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 9)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SSX2IP	Q9Y2D8³, ENSP00000340279⁴	I2D: score=1 STRING: ENSP00000340279
DDIT3	P35638³, ENSP00000340671⁴	I2D: score=1 STRING: ENSP00000340671
PCBD2	Q9H0N5³, ENSP00000254908⁴	I2D: score=1 STRING: ENSP00000254908
ZBTB3	Q9H5J0³, ENSP00000378286⁴	I2D: score=1 STRING: ENSP00000378286
ZNF496	Q96IT1³, ENSP00000294753⁴	I2D: score=1 STRING: ENSP00000294753

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Gene Ontology (GO): 2 biological process terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006351	transcription, DNA-templated	IEA	--
GO:0006355	regulation of transcription, DNA-templated	IEA	--

Find genes that share ontologies with SSX3 About GenesLikeMe

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for SSX3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for SSX3 gene (2 alternative transcripts):

NM_021014.3 NM_175711.1

Unigene Cluster for SSX3:

Synovial sarcoma, X breakpoint 3

Hs.558445 [show with all ESTs]

Unigene Representative Sequence: NM_021014

3 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000298396(uc004djd.1) ENST00000376895 ENST00000376893(uc004dje.3 uc010nic.3)

miRNA Products:		Block miRNA regulation of human, mouse, rat SSX3 using miScript Target Protectors
		3 qRT-PCR Assays for microRNAs that regulate SSX3:
		hsa-miR-199b-3p hsa-miR-199a-3p hsa-miR-3129-5p
		SwitchGear 3'UTR luciferase reporter plasmid: SSX3 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for SSX3
		Predesigned siRNA for gene silencing in human, mouse, rat SSX3

Clone Products:		OriGene clones in human, mouse for SSX3 (see all 9) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): SSX3 (NM_021014)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SSX3
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SSX3

Primer Products:		OriGene qPCR primer pairs and template standards for SSX3 OriGene qSTAR qPCR primer pairs in human, mouse for SSX3
		Pre-validated RT² qPCR Primer Assay in human, mouse / rat SSX3
		QuantiTect SYBR Green Assays in human, mouse, rat SSX3
		QuantiFast Probe-based Assays in human, mouse, rat SSX3

Additional mRNA sequence:

AK310348.1 AK310513.1 BC005904.1 BC103862.1 S82471.1 U90840.1

3 DOTS entries:

DT.100822740 DT.95157177 DT.121307474

10 AceView cDNA sequences:

NM_175711 BC005904 NM_021014 AA609599 S82471 U90840 BF184274 BX283846

BU189304 BG722220

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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SSX3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: --

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SSX3 Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

SSX3 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.558445

Custom PCR Arrays for SSX3

Primer Products:		OriGene qPCR primer pairs and template standards for SSX3 OriGene qSTAR qPCR primer pairs in human, mouse for SSX3
		Pre-validated RT² qPCR Primer Assay in human, mouse / rat SSX3
		QuantiTect SYBR Green Assays in human, mouse, rat SSX3
		QuantiFast Probe-based Assays in human, mouse, rat SSX3

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SSX3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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--

ENSEMBL Gene Tree for SSX3 (if available)
TreeFam Gene Tree for SSX3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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Paralogs for SSX3 gene

SSX5² SSX2B² SSX2² SSX4² SSX7² SSX4B² SSX1²

16 SIMAP similar genes for SSX3 using alignment to 2 protein entries: SSX3_HUMAN (see all proteins):

SSX2B SS18/SSX2 fusion SSX10 SSX9 SSX5 SSX7

SSX2 SSX6 SSX4B SSX1 SSX4 SSX8

SYT-SSX2 SS18/SSX1 fusion SYT-SSX1 SSX-HSTT

Find genes that share paralogs with SSX3 About GenesLikeMe

2 Pseudogenes.org Pseudogenes for SSX3
PGOHUM00000241317 PGOHUM00000241778

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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SNP ID	Valid	Clinical significance	Chr X pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs183063219^1,2		--	48124949(+)	`AGGATC/TGCTTT`	1	--	ds500¹		0	--	--	--	--
rs189037398^1,2		--	48125063(+)	`CTCTGA/GAGGCT`	1	--	ds500¹		0	--	--	--	--
rs7889704^1,2	C,A	--	48125142(+)	`cagccA/Tggaca`	1	--	ds500¹		0	--	--	--	--
rs182754561^1,2		--	48125260(+)	`GATGTC/TGCTCC`	1	--	ds500¹		0	--	--	--	--
rs72619013^1,2	C	--	48125280(+)	`AACAGC/TGCTCA`	1	--	ds500¹		0	--	--	--	--
rs145506332^1,2	C	--	48125362(+)	`TTTCCC/TAAAGA`	1	--	ds500¹		0	--	--	--	--
rs12559241^1,2	C,H	--	48125463(+)	`GACTGA/CTACAG`	1	--	ut3¹ ese³		0	--	--	--	--
rs72172699^1,2	C	--	48125579(+)	`ACTTG-/GTGT GTGTCTGTGTG`	1	--	ut3¹		0	--	--	--	--
rs71822704^1,2	C	--	48125586(+)	`GTGTG-/TCTGTGT`	1	--	ut3¹		0	--	--	--	--
rs3125215^1,2	C,H	--	48125587(+)	`TGTGTG/CTGTGT`	1	--	ut3¹ ese³		2		NA	4

HapMap Linkage Disequilibrium report for SSX3 (48205863 - 48216142 bp)

Structural Variations
Database of Genomic Variants (DGV) 6 variations for SSX3: About this table

Variant ID	Type	Subtype	PubMed ID
esv2671998	CNV	Deletion	23128226
nsv508769	CNV	Insertion	20534489
esv25781	CNV	Gain	19812545
nsv523595	CNV	Gain	19592680
esv32909	CNV	Gain+Loss	17666407
nsv7441	OTHER	Inversion	18451855

Locus Specific Mutation Databases (LSDB): SSX3

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing SSX3

DNA2.0 Custom Variant and Variant Library Synthesis for SSX3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 300325 OMIM disorders: --

2 diseases for SSX3:
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synovial sarcoma sarcoma

1 inferred disease relationship from the University of Copenhagen DISEASES database for SSX3:

Synovial sarcoma

Find genes that share disorders with SSX3 About GenesLikeMe

2 Novoseek inferred disease relationships for SSX3 gene About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
sarcoma synovial	86.1	2	8697803 (2)
melanoma	43	1	9378559 (1)

Export disorders for SSX3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for SSX3 gene, integrated from 10 sources (see all 11):
(articles sorted by number of sources associating them with SSX3)

Utopia: connect your pdf to the dynamic
world of online information

A novel Kruppel-associated box containing the SSX gene (SSX3) on the human X chromosome is not implicated in t(X;18)-positive synovial sarcomas. (PubMed id 8697803)^{1, 2, 3, 9} de Leeuw B.... Geurts van Kessel A. (Cytogenet. Cell Genet. 1996)
SSX: a multigene family with several members transcribed in normal testis and human cancer. (PubMed id 9378559)^{1, 2, 3, 9} Gure A.O.... Chen Y.-T. (Int. J. Cancer 1997)
The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP. (PubMed id 12007189)^{1, 2, 9} de Bruijn D.R.H....van Kessel A.G. (Genes Chromosomes Cancer 2002)
The DNA sequence of the human X chromosome. (PubMed id 15772651)^{1, 2} Ross M.T.... Bentley D.R. (Nature 2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S.... Malek J. (Genome Res. 2004)
Heterogeneous expression of the SSX cancer/testis antigens in human melanoma lesions and cell lines. (PubMed id 10749136)^{1, 9} dos Santos N.R.... Geurts van Kessel A. (Cancer Res. 2000)
An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)¹ Ravasi T....Hayashizaki Y. (Cell 2010)
A multigene predictor of metastatic outcome in early stage hormone receptor-negative and triple-negative breast cancer. (PubMed id 20946665)¹ Yau C....Benz C.C. (Breast Cancer Res. 2010)
The SSX gene family: characterization of 9 complete genes. (PubMed id 12216073)¹ Gure A.O.... Chen Y.-T. (Int. J. Cancer 2002)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 10214	HGNC: 11337	AceView: SSX3	Ensembl:ENSG00000165584	euGenes: HUgn10214
ECgene: SSX3	H-InvDB: SSX3

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for SSX3	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for SSX3	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for SSX3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for SSX3 gene:
Search GeneIP for patents involving SSX3

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from genOway)
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	Browse OriGene Antibodies		OriGene RNAi products in human, mouse, rat for SSX3
	OriGene qPCR primer pairs and template standards for SSX3		OriGene Protein Over-expression Lysate for SSX3
	OriGene MassSpec for SSX3		OriGene clones in human, mouse for SSX3
	OriGene qSTAR qPCR primer pairs in human, mouse for SSX3		OriGene Purified Protein for SSX3
	Browse OriGene ORF clones		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for SSX3		OriGene Custom Protein Services for SSX3

	Block miRNA regulation of human, mouse, rat SSX3 using miScript Target Protectors		SeqTarget long-range PCR primers for resequencing SSX3
	DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SSX3		Predesigned siRNA for gene silencing in human, mouse, rat SSX3
	QuantiFast Probe-based Assays in human, mouse, rat SSX3		QuantiTect SYBR Green Assays in human, mouse, rat SSX3
	Custom PCR Arrays for SSX3		Search Chromatin IP Primers for SSX3
	Pre-validated RT² qPCR Primer Assay in human, mouse / rat SSX3		GeneGlobe Interaction Network for SSX3
	Regulatory tfbs in SSX3 promoter

	GenScript Custom Purified and Recombinant Proteins Services for SSX3		GenScript cDNA clones with any tag delivered in your preferred vector for SSX3
	GenScript Custom Assay Services for SSX3		GenScript Custom overexpressing Cell Line Services for SSX3
	CloneReady with Over 120,000 Genes		Gene Synthesis: Any Gene in Any Vector
	Vector-based siRNA and miRNA, Ready for Transfection		Gene Mutant Library, Variants up to 10^11
	Plasmid Preparation		Custom Peptide Services

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	Novus Tissue Slides
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SSX3

	SwitchGear 3'UTR luciferase reporter plasmids for SSX3
	SwitchGear Promoter luciferase reporter plasmids for SSX3

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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SSX3

Browse compounds at ApexBio

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genOway: Develop your customized and physiologically relevant rodent model for SSX3

	antibodies-online antibodies for SSX3 (16 products)
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	antibodies-online peptides for SSX3
	antibodies-online proteins for SSX3 (5 products)

GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 2 Nov 2014 , 8 Jan 2015

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The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes SSX3 gene at Home site.

Version: 3.12.304 29 Jan 2015
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SSX3 Gene

Synovial Sarcoma, X Breakpoint 3

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SSX3 Gene

Synovial Sarcoma, X Breakpoint 3

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