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SSX3 Gene

protein-coding   GIFtS: 49
GCID: GC0XM048205

Synovial Sarcoma, X Breakpoint 3
  See related diseases
at
MalaCards
 

Aliases
for SSX3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Synovial Sarcoma, X Breakpoint 31 2
Cancer/Testis Antigen 5.32 3
CT5.32 3
Kruppel-Associated Box Containing Gene Product SSX32
Protein SSX32

External Ids:    HGNC: 113371   Entrez Gene: 102142   Ensembl: ENSG000001655847   OMIM: 3003255   UniProtKB: Q999093   

Export aliases for SSX3 gene to outside databases

Previous GC identifers: GC0XM047008 GC0XM046466 GC0XM047200 GC0XM047251 GC0XM047962 GC0XM048090 GC0XM045914


Summaries
for SSX3 gene

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SSX3 Gene:
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins.
These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral
and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based
immunotherapy. While some of the related SSX genes are involved in t(X;18)(p11.2;q11.2) translocations that are
characteristically found in all synovial sarcomas, this gene does not appear to be involved in such
translocations. (provided by RefSeq, Jul 2013)

GeneCards Summary for SSX3 Gene:
SSX3 (synovial sarcoma, X breakpoint 3) is a protein-coding gene. Diseases associated with SSX3 include synovial sarcoma, and sarcoma. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is SSX5.

UniProtKB/Swiss-Prot: SSX3_HUMAN, Q99909
Function: Could act as a modulator of transcription




Genomic Views
for SSX3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000023.11  NT_079573.5  NC_018934.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SSX3 gene promoter:
         C/EBPbeta   HNF-1A   C/EBPalpha   POU2F1   HNF-1   POU2F1a   POU2F1b   Sox9   POU2F1c   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SSX3 promoter sequence
   Search Chromatin IP Primers for SSX3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SSX3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp11.23   Ensembl cytogenetic band:  Xp11.23   HGNC cytogenetic band: Xp11.23

SSX3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SSX3 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM048205:  view genomic region     (about GC identifiers)

Start:
 48,205,863 bp from pter      End:
 48,216,142 bp from pter
Size:
 10,280 bases      Orientation:
 minus strand

Proteins
for SSX3 gene

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: SSX3_HUMAN, Q99909 (See protein sequence)
Recommended Name: Protein SSX3  
Size: 188 amino acids; 21697 Da
Subunit: Interacts with SSX2IP
Secondary accessions: O60223 Q5JQZ3 Q9BRW7
Alternative splicing: 2 isoforms:  Q99909-1   Q99909-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SSX3: NX_Q99909

Explore proteomics data for SSX3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

    • See SSX3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_066294.1  
    ENSEMBL proteins: 
     ENSP00000298396   ENSP00000366092   ENSP00000366090  

    SSX3 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    Novus Biologicals SSX3 Proteins
    Novus Biologicals SSX3 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SSX3

    SSX3 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Abcam antibodies for SSX3
    Cloud-Clone Corp. Antibodies for SSX3
    Search ThermoFisher Antibodies for SSX3
    LSBio Antibodies in human, mouse, rat for SSX3

    SSX3 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse R&D Systems for biochemical assays
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SSX3
    Cloud-Clone Corp. CLIAs for SSX3

    Domains /
    Families
    for SSX3 gene

    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    TryGeneCards Plus    		 4 InterPro protein domains:
     IPR003655 Krueppel-associated_box-rel
     IPR019041 SSXRD_motif
     IPR028804 SSX
     IPR001909 Krueppel-associated_box

    Graphical View of Domain Structure for InterPro Entry Q99909

    ProtoNet protein and cluster: Q99909

    1 Blocks protein domain: IPB001909 KRAB box

    UniProtKB/Swiss-Prot: SSX3_HUMAN, Q99909
    Similarity: Belongs to the SSX family
    Similarity: Contains 1 KRAB-related domain


    SSX3 for domains           About GeneDecksing


    Function
    for SSX3 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SSX3_HUMAN, Q99909
    Function: Could act as a modulator of transcription

         Genatlas biochemistry entry for SSX3:
    protein SSX3 with homology to Kruppel associated box,KRAB,not implicated in t(X;18) synovial sarcoma

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding IEA--
         
    SSX3 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SSX3
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SSX3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SSX3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SSX3

    miRNA
    Products:            		Block miRNA regulation of human, mouse, rat SSX3 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate SSX3:
    hsa-miR-199b-3p hsa-miR-199a-3p hsa-miR-3129-5p
    SwitchGear 3'UTR luciferase reporter plasmid: SSX3 3' UTR sequence
    Inhib. RNA
    Products:            		OriGene RNAi products in human, mouse, rat for SSX3
    Predesigned siRNA for gene silencing in human, mouse, rat SSX3

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for SSX3

    Clone
    Products:             		 OriGene clones in human, mouse for SSX3 (see all 9)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): SSX3 (NM_021014)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SSX3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SSX3

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for SSX3
    Browse ESI BIO Cell Lines and PureStem Progenitors for SSX3 
    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SSX3


    Localization
    for SSX3 gene

    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus3
    extracellular1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IEA--

    SSX3 for ontologies           About GeneDecksing


    Pathways & Interactions
    for SSX3 gene

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SSX3
    Interactions:

        GeneGlobe Interaction Network for SSX3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    Selected Interacting proteins for SSX3 (Q999093 ENSP000002983964) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SSX2IPQ9Y2D83, ENSP000003402794I2D: score=1 STRING: ENSP00000340279
    DDIT3P356383, ENSP000003406714I2D: score=1 STRING: ENSP00000340671
    PCBD2Q9H0N53, ENSP000002549084I2D: score=1 STRING: ENSP00000254908
    ZBTB3Q9H5J03, ENSP000003782864I2D: score=1 STRING: ENSP00000378286
    ZNF496Q96IT13, ENSP000002947534I2D: score=1 STRING: ENSP00000294753
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--

    SSX3 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SSX3 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SSX3



    Transcripts
    for SSX3 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SSX3 gene (2 alternative transcripts): 
    NM_021014.3  NM_175711.1  

    Unigene Cluster for SSX3:

    Synovial sarcoma, X breakpoint 3
    Hs.558445  [show with all ESTs]
    Unigene Representative Sequence: NM_021014
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000298396(uc004djd.1) ENST00000376895 ENST00000376893(uc004dje.3 uc010nic.3)

    miRNA
    Products:             		 Block miRNA regulation of human, mouse, rat SSX3 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate SSX3:
    hsa-miR-199b-3p hsa-miR-199a-3p hsa-miR-3129-5p
    SwitchGear 3'UTR luciferase reporter plasmid: SSX3 3' UTR sequence
    Inhib. RNA
    Products:             		OriGene RNAi products in human, mouse, rat for SSX3
    Predesigned siRNA for gene silencing in human, mouse, rat SSX3
    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): SSX3 (NM_021014)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SSX3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SSX3
    Primer
    Products:            		OriGene qPCR primer pairs and template standards for SSX3
    OriGene qSTAR qPCR primer pairs in human, mouse for SSX3
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat SSX3
      QuantiTect SYBR Green Assays in human, mouse, rat SSX3
      QuantiFast Probe-based Assays in human, mouse, rat SSX3

    Additional mRNA sequence: 

    AK310348.1 AK310513.1 BC005904.1 BC103862.1 S82471.1 U90840.1 

    3 DOTS entries:

    DT.100822740  DT.95157177  DT.121307474 

    10 AceView cDNA sequences:

    NM_175711 BC005904 NM_021014 AA609599 S82471 U90840 BF184274 BX283846 
    BU189304 BG722220 

    GeneLoc Exon Structure


    Expression
    for SSX3 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SSX3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SSX3 Expression
    About this image

    SSX3 Protein expression data from MOPED1, PaxDb2 and MaxQB3:     About this image

    SSX3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.558445
        Custom PCR Arrays for SSX3
    Primer
    Products:    		OriGene qPCR primer pairs and template standards for SSX3
    OriGene qSTAR qPCR primer pairs in human, mouse for SSX3
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat SSX3
    QuantiTect SYBR Green Assays in human, mouse, rat SSX3
    QuantiFast Probe-based Assays in human, mouse, rat SSX3
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SSX3

    Orthologs
    for SSX3 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus    		   --

    ENSEMBL Gene Tree for SSX3 (if available)
    TreeFam Gene Tree for SSX3 (if available)

    Paralogs
    for SSX3 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SSX3 gene
    SSX52  SSX2B2  SSX22  SSX42  SSX72  SSX4B2  SSX12  
    16 SIMAP similar genes for SSX3 using alignment to 2 protein entries:     SSX3_HUMAN (see all proteins):
    SSX2B    SS18/SSX2 fusion    SSX10    SSX9    SSX5    SSX7
    SSX2    SSX6    SSX4B    SSX1    SSX4    SSX8
    SYT-SSX2    SS18/SSX1 fusion    SYT-SSX1    SSX-HSTT

    SSX3 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for SSX3
    PGOHUM00000241317 PGOHUM00000241778


    Genomic Variants
    for SSX3 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SSX3 (see all 280)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr X posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1830632191,2
    		--48124949(+) AGGATC/TGCTTT 1 -- ds50010--------
    rs1890373981,2
    		--48125063(+) CTCTGA/GAGGCT 1 -- ds50010--------
    rs78897041,2
    		C,A--48125142(+) cagccA/Tggaca 1 -- ds50010--------
    rs1827545611,2
    		--48125260(+) GATGTC/TGCTCC 1 -- ds50010--------
    rs726190131,2
    		C--48125280(+) AACAGC/TGCTCA 1 -- ds50010--------
    rs1455063321,2
    		C--48125362(+) TTTCCC/TAAAGA 1 -- ds50010--------
    rs125592411,2
    		C,H--48125463(+) GACTGA/CTACAG 1 -- ut31 ese30--------
    rs721726991,2
    		C--48125579(+) ACTTG-/GTGT  
      GTGTCT    GTGTG     		1 -- ut310--------
    rs718227041,2
    		C--48125586(+) GTGTG-/TCTGTGT 1 -- ut310--------
    rs31252151,2
    		C,H--48125587(+) TGTGTG/CTGTGT 1 -- ut31 ese32Minor allele frequency- C:0.00NA 4

    HapMap Linkage Disequilibrium report for SSX3 (48205863 - 48216142 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for SSX3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2671998CNV Deletion23128226
    nsv508769CNV Insertion20534489
    esv25781CNV Gain19812545
    nsv523595CNV Gain19592680
    esv32909CNV Gain+Loss17666407
    nsv7441OTHER Inversion18451855

    Locus Specific Mutation Databases (LSDB): SSX3

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SSX3
    DNA2.0 Custom Variant and Variant Library Synthesis for SSX3

    Disorders / Diseases
    for SSX3 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus    		 OMIM gene information: 300325    OMIM disorders: --

    4 diseases for SSX3:    About MalaCards
    synovial sarcoma    sarcoma    melanoma    breast cancer

    1 disease from the University of Copenhagen DISEASES database for SSX3:
    Synovial sarcoma

    SSX3 for disorders           About GeneDecksing

    2 Novoseek inferred disease relationships for SSX3 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    sarcoma synovial 86.1 2 8697803 (2)
    melanoma 43 1 9378559 (1)


    Export disorders for SSX3 gene to outside databases

    Publications
    for SSX3 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SSX3 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with SSX3)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel Kruppel-associated box containing the SSX gene (SSX3) on the human X chromosome is not implicated in t(X;18)-positive synovial sarcomas. (PubMed id 8697803)1, 2, 3, 9 de Leeuw B.... Geurts van Kessel A. (Cytogenet. Cell Genet. 1996)
    2. SSX: a multigene family with several members transcribed in normal testis and human cancer. (PubMed id 9378559)1, 2, 3, 9 Gure A.O.... Chen Y.-T. (Int. J. Cancer 1997)
    3. The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP. (PubMed id 12007189)1, 2, 9 de Bruijn D.R.H....van Kessel A.G. (Genes Chromosomes Cancer 2002)
    4. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (Nature 2005)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Heterogeneous expression of the SSX cancer/testis antigens in human melanoma lesions and cell lines. (PubMed id 10749136)1, 9 dos Santos N.R.... Geurts van Kessel A. (Cancer Res. 2000)
    7. An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (Cell 2010)
    8. A multigene predictor of metastatic outcome in early stage hormone receptor-negative and triple-negative breast cancer. (PubMed id 20946665)1 Yau C....Benz C.C. (Breast Cancer Res. 2010)
    9. The SSX gene family: characterization of 9 complete genes. (PubMed id 12216073)1 Gure A.O.... Chen Y.-T. (Int. J. Cancer 2002)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    External Searches for SSX3 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing SSX3 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10214 HGNC: 11337 AceView: SSX3 Ensembl:ENSG00000165584 euGenes: HUgn10214
    ECgene: SSX3 H-InvDB: SSX3

    Other Databases showing SSX3 gene

    (According to HUGE)
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    Specialized Databases showing SSX3 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for SSX3 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for SSX3 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for SSX3 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus    		Patent Information for SSX3 gene:
    Search GeneIP for patents involving SSX3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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    About This Section

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     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SSX3
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SSX3
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     LSBio Antibodies in human, mouse, rat for SSX3
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