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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SSX2IP Gene

protein-coding   GIFtS: 55
GCID: GC01M085109

Synovial Sarcoma, X Breakpoint 2 Interacting Protein

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Synovial Sarcoma, X Breakpoint 2 Interacting Protein1 2
Afadin DIL Domain-Interacting Protein2 3
ADIP2 3
SSX2-Interacting Protein2 3
Afadin- And Alpha-Actinin-Binding Protein2
KIAA09233

External Ids:    HGNC: 165091   Entrez Gene: 1171782   Ensembl: ENSG000001171557   OMIM: 6086905   UniProtKB: Q9Y2D83   

Export aliases for SSX2IP gene to outside databases

Previous GC identifers: GC00U991126 GC01M084247 GC01M084397 GC01M084531 GC01M084532 GC01M084821 GC01M084881 GC01M083219


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SSX2IP Gene:
This gene encodes a protein that binds the cancer-testis antigen Synovial Sarcoma X breakpoint 2 protein. The
encoded protein may regulate the activity of Synovial Sarcoma X breakpoint 2 protein in malignant cells.
Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3.
(provided by RefSeq, Oct 2009)

GeneCards Summary for SSX2IP Gene: 
SSX2IP (synovial sarcoma, X breakpoint 2 interacting protein) is a protein-coding gene. Diseases associated with SSX2IP include constrictive pericarditis, and synovial sarcoma, and among its related super-pathways are PAK Pathway. GO annotations related to this gene include protein binding and protein domain specific binding.

UniProtKB/Swiss-Prot: ADIP_HUMAN, Q9Y2D8
Function: Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and
heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system
through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and
alpha-actinin (By similarity)

Gene Wiki entry for SSX2IP Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_032977.9  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SSX2IP gene promoter:
         GATA-3   Bach2   ATF-2   POU3F2 (N-Oct-5a)   POU3F2   GATA-2   Evi-1   S8   NF-Y   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSSX2IP promoter sequence
   Search SABiosciences Chromatin IP Primers for SSX2IP

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SSX2IP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p22.3   Ensembl cytogenetic band:  1p22.3   HGNC cytogenetic band: 1p22.3

SSX2IP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SSX2IP gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M085109:  view genomic region     (about GC identifiers)

Start:
85,109,390 bp from pter      End:
85,156,486 bp from pter
Size:
47,097 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ADIP_HUMAN, Q9Y2D8 (See protein sequence)
Recommended Name: Afadin- and alpha-actinin-binding protein  
Size: 614 amino acids; 71236 Da
Subunit: Interacts with afadin and alpha-actinin (By similarity). Interacts with SSX2 and SSX3. Does not interact
with SSX1 and SSX4
Subcellular location: Cell junction, adherens junction (By similarity). Nucleus. Note=Not found at cell-matrix AJs
(By similarity)
Sequence caution: Sequence=BAA76767.2; Type=Erroneous initiation;
Secondary accessions: A8K8W0 B4DFE3 D3DT13 J3KR02 Q6P2P8 Q6ULS1 Q7L168 Q9UIX0
Alternative splicing: 3 isoforms:  Q9Y2D8-1   Q9Y2D8-2   Q9Y2D8-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SSX2IP: NX_Q9Y2D8

Explore proteomics data for SSX2IP at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9Y2D8

  • SSX2IP Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SSX2IP Protein Expression
    REFSEQ proteins (5 alternative transcripts): 
    NP_001159765.1  NP_001159766.1  NP_001159767.1  NP_001159889.1  NP_054740.3  

    ENSEMBL proteins: 
     ENSP00000340279   ENSP00000432261   ENSP00000474925   ENSP00000474480   ENSP00000473763  
     ENSP00000416067   ENSP00000412781   ENSP00000359644  

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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005913cell-cell adherens junction IEA--
    GO:0031252cell leading edge IEA--
    GO:0043234protein complex IDA--

    SSX2IP for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR021622 Afadin/alpha-actinin-bd

    Graphical View of Domain Structure for InterPro Entry Q9Y2D8

    ProtoNet protein and cluster: Q9Y2D8

    UniProtKB/Swiss-Prot: ADIP_HUMAN, Q9Y2D8
    Domain: Both the N-terminal (up to position 79) and the C-terminal (from position 304) sequences are required for
    interaction with SSX2


    SSX2IP for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ADIP_HUMAN, Q9Y2D8
    Function: Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and
    heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system
    through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and
    alpha-actinin (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI12007189
    GO:0019904protein domain specific binding IEA--
         
    SSX2IP for ontologies           About GeneDecksing


    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SSX2IP About                                                                                                See pathways by source

    SuperPathContained pathways About
    1PAK Pathway
    Epithelial Adherens Junctions0.36
    2Adherens junction
    Adherens junction

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for SSX2IP
        Epithelial Adherens Junctions


    1         Kegg Pathway  (Kegg details for SSX2IP):
        Adherens junction


    SSX2IP for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SSX2IP

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    5/20 Interacting proteins for SSX2IP (Q9Y2D81, 2, 3 ENSP000003402794) via UniProtKB, MINT, STRING, and/or I2D (see all 20)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SSX2Q163851, 3, ENSP000003387964EBI-2212028,EBI-2210673 I2D: score=2 STRING: ENSP00000338796
    SSX2BQ163851, 3EBI-2212028,EBI-2210673 I2D: score=2 
    ACTN2P356093, ENSP000003555374I2D: score=1 STRING: ENSP00000355537
    SSX3Q999093, ENSP000002983964I2D: score=1 STRING: ENSP00000298396
    MLLT4P551963, ENSP000003836234I2D: score=2 STRING: ENSP00000383623
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007155cell adhesion IEA--
    GO:0035020regulation of Rac protein signal transduction IEA--
    GO:2000145regulation of cell motility IEA--

    SSX2IP for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SSX2IP (ADIP)

    Search CenterWatch for drugs/clinical trials and news about SSX2IP / ADIP

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SSX2IP gene (5 alternative transcripts): 
    NM_001166293.1  NM_001166294.1  NM_001166295.1  NM_001166417.1  NM_014021.3  

    Unigene Cluster for SSX2IP:

    Synovial sarcoma, X breakpoint 2 interacting protein
    Hs.22587  [show with all ESTs]
    Unigene Representative Sequence: NM_001166417
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000342203(uc001dkf.3 uc001dki.3 uc010osa.2 uc001dkj.3)
    ENST00000481102(uc009wci.3) ENST00000476905(uc001dkk.1) ENST00000605755
    ENST00000603677 ENST00000490476 ENST00000459708 ENST00000460500 ENST00000422026
    ENST00000437941(uc001dkh.3 uc010orz.2 uc001dkg.3) ENST00000370612

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    Additional mRNA sequence: 

    AB023140.1 AK001710.1 AK021515.1 AK023097.1 AK292475.1 AK294057.1 AK307336.1 AK316472.1 
    AL133046.1 AY367055.1 AY651262.1 BC033637.1 BC035580.1 BC064389.1 

    12 DOTS entries:

    DT.443120  DT.91724867  DT.95364110  DT.91819070  DT.87046250  DT.100027963  DT.97818472  DT.95148373 
    DT.95364109  DT.121357808  DT.40124571  DT.100793289 

    24/226 AceView cDNA sequences (see all 226):

    F05006 BM721181 AI572351 AU133150 F12492 AA743113 BM728884 CB159291 
    AA307820 AI274784 CA428511 AA721219 AI421459 AL133046 BI520350 CA415280 
    BU631256 BM679602 CR611558 F02193 AB023140 AI286099 AW592781 AI453170 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for SSX2IP (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15a · 15b
    SP1:        -                                                                                               -     -               
    SP2:                                                                                      -                 -                     
    SP3:                                                                                      -                 -     -               
    SP4:                                                                                      -                 -     -               
    SP5:                                                                                                                              


    ECgene alternative splicing isoforms for SSX2IP

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SSX2IP expression in normal human tissues (normalized intensities)      SSX2IP embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CACTCACCCT
    SSX2IP Expression
    About this image


    SSX2IP expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/6 selected tissues (see all 6) fully expand
     
     Testis (Reproductive System)    fully expand to see all 3 entries
             Leydig Cells Testis Interstitium
             Testis Interstitium
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             Proerythroblasts Hematopoietic Bone Marrow
             cord blood   
     
     Intestine (Gastrointestinal Tract)
             small intestine   
     
     Umbilical Cord (Extraembryonic Tissues)
             cord blood   
     
     Eye (Sensory Organs)
             lens   

    See SSX2IP Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SSX2IP

    SOURCE GeneReport for Unigene cluster: Hs.22587

    UniProtKB/Swiss-Prot: ADIP_HUMAN, Q9Y2D8
    Tissue specificity: Widely expressed, with the highest expression in brain, intermediate expression in kidney,
    testis, spinal cord, liver, heart, lung, skeletal muscle, ovary, fetal liver and fetal brain, and little to no
    expression in pancreas and spleen. All specific brain regions showed intermediate to high expression, with
    highest expression in amygdala. Also expressed in fetal tissues, mainly in liver and brain

        SABiosciences Expression via Pathway-Focused PCR Array including SSX2IP: 
              Adherens Junctions in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SSX2IP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SSX2IP gene from 7/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ssx2ip1 , 5 synovial sarcoma, X breakpoint 2 interacting protein1, 5 84.15(n)1
    87.62(a)1
      3 (71.03 cM)5
    991671  NM_138744.31  NP_620083.11 
     1464046425 
    chicken
    (Gallus gallus)
    Aves SSX2IP1 synovial sarcoma, X breakpoint 2 interacting protein 75.64(n)
    75.27(a)
      424532  NM_001044656.1  NP_001038121.1 
    lizard
    (Anolis carolinensis)
    Reptilia SSX2IP6
    --
    (see all 3)
    Uncharacterized protein
    (see all 3)
    69(a)
    36(a)
    (see all 3)
    1 ↔ 1
    possible ortholog
    (see all 3)
    GL343194.1(9853238-9888522)
    5(121583218-121586505)
    African clawed frog
    (Xenopus laevis)
    Amphibia BU914026.12   -- 75.79(n)    BU914026.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc733142 hypothetical protein MGC73314 72.7(n)   393808  BC060934.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G188761 Afadin/alpha-actinin-binding protein 43.14(n)
    26.73(a)
      816403  NM_179650.1  NP_849981.1 
    rice
    (Oryza sativa)
    Liliopsida Os08g02429001 hypothetical protein 42.44(n)
    27.33(a)
      4345045  NM_001067879.1  NP_001061344.1 


    ENSEMBL Gene Tree for SSX2IP (if available)
    TreeFam Gene Tree for SSX2IP (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SSX2IP gene

    SSX2IP for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SSX2IP
    PGOHUM00000237700


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1005 SNPs in SSX2IP are shown (see all 1005)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs108744541,2
    C,F,A,H--85108904(+) CAGCAG/ATAAAC 5 -- ds500114Minor allele frequency- A:0.45NS EA NA WA 724
    rs1924269611,2
    --85108971(+) AGATTG/TTAAGT 5 -- ds50010--------
    rs1457554691,2
    --85108975(+) TGTAAC/GTGCTC 5 -- ds50010--------
    rs1383572681,2
    --85109034(+) CTGTAA/GGTGGA 5 -- ds50010--------
    rs1850198491,2
    --85109051(+) GTCTCC/TTTCAG 5 -- ds50010--------
    rs1492513211,2
    --85109256(+) ATACTC/GTATAT 5 -- ds50010--------
    rs1470633871,2
    C--85109333(+) AGAAA-/GAGGAGTT 5 -- ds50010--------
    rs1438014571,2
    --85109364(+) ACTTAC/TAGTCC 5 -- ds50010--------
    rs1883096071,2
    --85109366(+) TTATAA/GTCCAT 5 -- ds50010--------
    rs1931932401,2
    --85109453(+) CTAGGC/TACATG 5 -- ut310--------

    HapMap Linkage Disequilibrium report for SSX2IP (85109390 - 85156486 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for SSX2IP: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SSX2IP
    DNA2.0 Custom Variant and Variant Library Synthesis for SSX2IP

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 608690    OMIM disorders: --

    7 diseases for SSX2IP:    About MalaCards
    constrictive pericarditis    synovial sarcoma    pericarditis    sarcoma
    acute myeloid leukemia    myeloid leukemia    leukemia

    1 disease from the University of Copenhagen DISEASES database for SSX2IP:
    Constrictive pericarditis

    SSX2IP for disorders           About GeneDecksing

    Genetic Association Database (GAD): SSX2IP

    Export disorders for SSX2IP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SSX2IP gene, integrated from 9 sources (see all 34):
    (articles sorted by number of sources associating them with SSX2IP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP. (PubMed id 12007189)1, 2, 9 de Bruijn D.R.H....van Kessel A.G. (2002)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)1, 2 Nagase T.... Ohara O. (1999)
    5. SSX2IP: an emerging role in cancer. (PubMed id 17904521)1, 9 Breslin A....Guinn B.A. (2007)
    6. Humoral detection of leukaemia-associated antigens in presentation acute myeloid leukaemia. (PubMed id 16112646)1, 9 Guinn B.-A.... Mufti G.J. (2005)
    7. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (2013)
    8. SSX2IP promotes metastasis and chemotherapeutic resist ance of hepatocellular carcinoma. (PubMed id 23452395)1 Li P....Huo K. (2013)
    9. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 117178 HGNC: 16509 AceView: SSX2IP Ensembl:ENSG00000117155 euGenes: HUgn117178
    ECgene: SSX2IP Kegg: 117178 H-InvDB: SSX2IP

    (According to HUGE)
    About This Section
    HUGE: KIAA0923

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SSX2IP Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for SSX2IP Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SSX2IP gene:
    Search GeneIP for patents involving SSX2IP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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