Aliases for SSX2IP Gene
Aliases for SSX2IP Gene
External Ids for SSX2IP Gene
- HGNC: 16509
- Entrez Gene: 117178
- Ensembl: ENSG00000117155
- OMIM: 608690
- UniProtKB: Q9Y2D8
Previous GeneCards Identifiers for SSX2IP Gene
- GC00U991126
- GC01M084247
- GC01M084397
- GC01M084531
- GC01M084532
- GC01M084821
- GC01M084881
- GC01M085109
- GC01M083219
Summaries for SSX2IP Gene
-
This gene encodes a protein that binds the cancer-testis antigen Synovial Sarcoma X breakpoint 2 protein. The encoded protein may regulate the activity of Synovial Sarcoma X breakpoint 2 protein in malignant cells. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Oct 2009]
GeneCards Summary for SSX2IP Gene
SSX2IP (Synovial Sarcoma, X Breakpoint 2 Interacting Protein) is a Protein Coding gene. Among its related pathways are Adherens junction and PAK Pathway. GO annotations related to this gene include protein domain specific binding.
UniProtKB/Swiss-Prot for SSX2IP Gene
-
Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin (By similarity). Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via activation of Rac signaling (By similarity). Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubule nucleation at mitotic spindle poles (PubMed:23816619). Involved in ciliogenesis (PubMed:24356449). It is required for targeted recruitement of the BBSome, CEP290, RAB8, and SSTR3 to the cilia (PubMed:24356449).
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SSX2IP Gene
Genomics for SSX2IP Gene
Regulatory Elements for SSX2IP Gene
Enhancers for SSX2IP Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around SSX2IP on UCSC Golden Path with GeneCards custom track
Promoters for SSX2IP Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|
ENSRs around SSX2IP on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the SSX2IP gene promoter:
Regulatory Element Products
Genomic Location for SSX2IP Gene
- Chromosome:
- 1
- Start:
- 84,643,707 bp from pter
- End:
- 84,690,803 bp from pter
- Size:
- 47,097 bases
- Orientation:
- Minus strand
Genomic View for SSX2IP Gene
Genes around SSX2IP on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p22.3 by Ensembl
- 1p22.3 by Entrez Gene
- 1p22.3 by HGNC
SSX2IP Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SSX2IP Gene
Proteins for SSX2IP Gene
-
Protein details for SSX2IP Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9Y2D8-ADIP_HUMAN
- Recommended name:
- Afadin- and alpha-actinin-binding protein
- Protein Accession:
- Q9Y2D8
- A8K8W0
- B4DFE3
- D3DT13
- J3KR02
- Q6P2P8
- Q6ULS1
- Q7L168
- Q9UIX0
Protein attributes for SSX2IP Gene
- Size:
- 614 amino acids
- Molecular mass:
- 71236 Da
- Quaternary structure:
-
- Interacts with afadin and alpha-actinin (By similarity). Interacts with VAV2 (By similarity). Interacts with SSX2 and SSX3. Does not interact with SSX1 and SSX4. Interacts with PCM1 (By similarity).
- Miscellaneous:
-
- Acts as an acute myeloid leukemia-associated antigen and may be used as a potential immunotherapy target for leukemia (PubMed:17686061, PubMed:19179477).
- SequenceCaution:
-
- Sequence=BAA76767.2; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for SSX2IP Gene
Post-translational modifications for SSX2IP Gene
Other Protein References for SSX2IP Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for SSX2IP
- Abcam antibodies for SSX2IP (Q9Y2D8)
- Invitrogen Antibodies for SSX2IP
- antibodies-online Antibodies for SSX2IP: See all 40
- GeneTex SSX2IP antibody for SSX2IP
Protein Products
-
OriGene Purified Proteins for SSX2IP
- Search Origene for MassSpec and Protein Over-expression Lysates for SSX2IP
- Origene Custom Protein Services for SSX2IP
- antibodies-online Proteins for SSX2IP: See all 6
- Search antibodies-online for peptides
- Search GeneTex for Proteins for SSX2IP
Assay Products
- antibodies-online Kits for SSX2IP: See all 7
No data available for DME Specific Peptides for SSX2IP Gene
Domains & Families for SSX2IP Gene
Protein Domains for SSX2IP Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for SSX2IP Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9Y2D8UniProtKB/Swiss-Prot:
ADIP_HUMAN :- Both the N-terminal (up to position 79) and the C-terminal (from position 304) sequences are required for interaction with SSX2.
- Belongs to the ADIP family.
- Domain:
-
- Both the N-terminal (up to position 79) and the C-terminal (from position 304) sequences are required for interaction with SSX2.
- Family:
-
- Belongs to the ADIP family.
No data available for Gene Families for SSX2IP Gene
Function for SSX2IP Gene
Molecular function for SSX2IP Gene
- UniProtKB/Swiss-Prot Function:
- Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin (By similarity). Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via activation of Rac signaling (By similarity). Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubule nucleation at mitotic spindle poles (PubMed:23816619). Involved in ciliogenesis (PubMed:24356449). It is required for targeted recruitement of the BBSome, CEP290, RAB8, and SSTR3 to the cilia (PubMed:24356449).
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for SSX2IP gene
-
ViGene Biosciences ready-to-package AAV shRNAs for SSX2IP gene
- Search ViGene Biosciences for SSX2IP
CRISPR Products
-
OriGene CRISPR knockouts for SSX2IP
-
Santa Cruz Biotechnology (SCBT) CRISPR for SSX2IP
- GenScript: Design CRISPR guide RNA sequences for SSX2IP
miRNA for SSX2IP Gene
- miRTarBase miRNAs that target SSX2IP
-
- hsa-mir-193b-3p (MIRT016383)
- hsa-mir-155-5p (MIRT020713)
- hsa-mir-339-5p (MIRT042758)
- hsa-mir-92a-3p (MIRT049125)
- hsa-mir-222-3p (MIRT053144)
- hsa-mir-221-3p (MIRT053145)
- hsa-mir-338-3p (MIRT053532)
- hsa-mir-374a-5p (MIRT148608)
- hsa-mir-26a-5p (MIRT346489)
- hsa-mir-26b-5p (MIRT346490)
- hsa-mir-106b-5p (MIRT439534)
- hsa-mir-20a-5p (MIRT439535)
- hsa-mir-6864-3p (MIRT718023)
- hsa-mir-3672 (MIRT718024)
- hsa-mir-5189-3p (MIRT718025)
- hsa-mir-4524a-3p (MIRT718026)
- hsa-mir-181d-5p (MIRT726438)
- hsa-mir-181c-5p (MIRT726439)
- hsa-mir-181b-5p (MIRT726440)
- hsa-mir-181a-5p (MIRT726441)
- hsa-mir-93-5p (MIRT726442)
- hsa-mir-519d-3p (MIRT726443)
- hsa-mir-20b-5p (MIRT726444)
- hsa-mir-17-5p (MIRT726445)
miRNA Products
- Search ViGene Biosciences for SSX2IP
Clone Products
- OriGene clones in human for SSX2IP
- OriGene ORF clones in human,mouse,rat for SSX2IP
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: cDNA clones in your preferred vector
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Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for SSX2IP gene
-
ViGene Biosciences lentiviral particle packaged cDNA for SSX2IP gene
-
ViGene Biosciences ready-to-package AAV shRNAs for SSX2IP gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SSX2IP Gene
Localization for SSX2IP Gene
Subcellular locations from UniProtKB/Swiss-Prot for SSX2IP Gene
- Cell junction, adherens junction. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton, cilium basal body. Note=Not found at cell-matrix AJs. {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| nucleus | 4 |
| cytosol | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005912 | adherens junction | IEA | -- |
| GO:0031252 | cell leading edge | IEA | -- |
| GO:0034451 | centriolar satellite | IDA | 23816619 |
| GO:0036064 | ciliary basal body | IDA | 24356449 |
Pathways & Interactions for SSX2IP Gene
More details on SuperPathways for SSX2IP| Superpath | Contained pathways | |
|---|---|---|
| 1 | Adherens junction | |
| 2 | PAK Pathway |
Pathways by source for SSX2IP Gene
1 KEGG pathway for SSX2IP Gene
1 Qiagen pathway for SSX2IP Gene
Interacting Proteins for SSX2IP Gene
Selected Interacting proteins:
Q9Y2D8-ADIP_HUMAN
ENSP00000340279
for SSX2IP Gene via
MINT
STRING
UniProtKB
I2D
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0051297 | centrosome organization | IMP | 23816619 |
| GO:2000145 | regulation of cell motility | IEA | -- |
No data available for SIGNOR curated interactions for SSX2IP Gene
Transcripts for SSX2IP Gene
mRNA/cDNA for SSX2IP Gene
- (12) REFSEQ mRNAs :
- (14) Additional mRNA sequences :
- (226) Selected AceView cDNA sequences:
- (10) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for SSX2IP Gene
- Synovial sarcoma, X breakpoint 2 interacting protein:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for SSX2IP
-
Santa Cruz Biotechnology (SCBT) CRISPR for SSX2IP
- GenScript: Design CRISPR guide RNA sequences for SSX2IP
miRNA Products
- Search ViGene Biosciences for SSX2IP
Clone Products
- OriGene clones in human for SSX2IP
- OriGene ORF clones in human,mouse,rat for SSX2IP
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: cDNA clones in your preferred vector
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | ^ | 14 | ^ | 15a | · | 15b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||||||||||||||
| SP6: | - | ||||||||||||||||||||||||||||||||||||||||
| SP7: |
Expression for SSX2IP Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Testis (Reproductive System)
- Leydig Cells Testis Interstitium
- Seminiferous Tubules
- Testis Interstitium
-
Blood (Hematopoietic System)
- Proerythroblasts Hematopoietic Bone Marrow
mRNA differential expression in normal tissues according to GTEx for SSX2IP Gene
This gene is overexpressed in Testis (x5.3) and Brain - Frontal Cortex (BA9) (x4.2).
This gene is overexpressed in Liver (41.9) and Testis (20.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for SSX2IP Gene
SOURCE GeneReport for Unigene cluster for SSX2IP Gene Hs.22587
mRNA Expression by UniProt/SwissProt for SSX2IP Gene
Q9Y2D8-ADIP_HUMAN
Tissue specificity:
Widely expressed, with the highest expression in brain, intermediate expression in kidney, testis, spinal cord, liver, heart, lung, skeletal muscle, ovary, fetal liver and fetal brain, and little to no expression in pancreas and spleen. All specific brain regions showed intermediate to high expression, with highest expression in amygdala. Also expressed in fetal tissues, mainly in liver and brain.
Primer Products
-
OriGene qPCR primer pairs for SSX2IP
-
OriGene qPCR primer pairs and template standards for SSX2IP
Orthologs for SSX2IP Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | SSX2IP 35 |
|
||
| SSX2IP 36 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | SSX2IP 35 |
|
||
| SSX2IP 36 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Ssx2ip 35 |
|
||
| Ssx2ip 16 |
|
||||
| Ssx2ip 36 |
|
OneToOne | |||
| chimpanzee (Pan troglodytes) |
Mammalia | SSX2IP 35 |
|
||
| SSX2IP 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Ssx2ip 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | SSX2IP 36 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | SSX2IP 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | SSX2IP 35 |
|
||
| SSX2IP 36 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | SSX2IP 36 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | ssx2ip 35 |
|
||
| Str.8904 35 |
|
||||
| zebrafish (Danio rerio) |
Actinopterygii | LOC100534665 35 |
|
||
| zgc73314 35 |
|
||||
| ssx2ip 36 |
|
OneToMany | |||
| SSX2IP (2 of 3) 36 |
|
OneToMany | |||
| SSX2IP (3 of 3) 36 |
|
OneToMany | |||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | AT2G18876 35 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os08g0242900 35 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 36 |
|
OneToOne |
- Species with no ortholog for SSX2IP:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for SSX2IP Gene
Pseudogenes.org Pseudogenes for SSX2IP Gene
No data available for Paralogs for SSX2IP Gene
Variants for SSX2IP Gene
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1057746 | - | 84,647,546(-) | GAGAA(C/G/T)GTACA | nc-transcript-variant, reference, missense, utr-variant-3-prime | |
| rs1927 | -- | 84,646,497(+) | TTACT(A/G)TACTG | nc-transcript-variant, utr-variant-3-prime | |
| rs3782 | -- | 84,644,642(-) | AGAGA(G/T)GTTTT | nc-transcript-variant, utr-variant-3-prime | |
| rs722789 | -- | 84,665,623(-) | CTTTA(G/T)TGGTT | intron-variant | |
| rs1538848 | -- | 84,690,036(+) | CCCCC(A/C)ACGCC | intron-variant |
Residual Variation Intolerance Score:
32.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.84;
17.61% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for SSX2IP Gene
- HapMap Linkage Disequilibrium report
- SSX2IP
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SSX2IP Gene
Disorders for SSX2IP Gene
Relevant External Links for SSX2IP
No disorders were found for SSX2IP Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SSX2IP Gene
Publications for SSX2IP Gene
- The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP. (PMID: 12007189) de Bruijn D.R.H. … van Kessel A.G. (Genes Chromosomes Cancer 2002) 3 4 23 67
- SSX2IP: an emerging role in cancer. (PMID: 17904521) Breslin A. … Guinn B.A. (Biochem. Biophys. Res. Commun. 2007) 3 23
- Humoral detection of leukaemia-associated antigens in presentation acute myeloid leukaemia. (PMID: 16112646) Guinn B.-A. … Mufti G.J. (Biochem. Biophys. Res. Commun. 2005) 3 23
- Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes. (PMID: 25281560) Lambert J.P. … Gingras A.C. (J Proteomics 2015) 3
- Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2. (PMID: 25476789) Galligan J.T. … Howley P.M. (J. Proteome Res. 2015) 3
Products for SSX2IP Gene
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- Custom Antibody ServicesOriGene Antibodies for SSX2IP
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for SSX2IP
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- Browse OriGene Inhibitory RNA Products For SSX2IP
- OriGene qPCR primer pairs for SSX2IP
- OriGene qPCR primer pairs and template standards for SSX2IP
- OriGene CRISPR knockouts for SSX2IP
- OriGene clones in human for SSX2IP
- OriGene ORF clones in human,mouse,rat for SSX2IP
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for SSX2IP
- GenScript Custom Assay Services for SSX2IP
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- GenScript: Design CRISPR guide RNA sequences for SSX2IP
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- Novus Biologicals Antibodies for SSX2IP
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- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- antibodies-online Antibodies for SSX2IP: See all 40
- antibodies-online Kits for SSX2IP: See all 7
- antibodies-online Proteins for SSX2IP: See all 6
- Search antibodies-online for peptides
- GeneTex SSX2IP antibody for SSX2IP
- Search GeneTex for Proteins for SSX2IP
- ViGene Biosciences adenoviral particle packaged cDNA for SSX2IP gene
- ViGene Biosciences lentiviral particle packaged cDNA for SSX2IP gene
- ViGene Biosciences lentiviral particle packaged cDNA for SSX2IP gene
- ViGene Biosciences ready-to-package AAV shRNAs for SSX2IP gene
- ViGene Biosciences ready-to-package AAV shRNAs for SSX2IP gene
- ViGene Biosciences ready-to-package AAV shRNAs for SSX2IP gene
- Search ViGene Biosciences for SSX2IP
- Search ViGene Biosciences for SSX2IP
Sources for SSX2IP Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
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