Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SSX1 Gene

protein-coding   GIFtS: 52
GCID: GC0XP048114

synovial sarcoma, X breakpoint 1

 Explore 13 diseases affiliated with
SSX1 via our new
 Human Malady Compendium 
Biological research products
for SSX1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Synovial Sarcoma, X Breakpoint 11 2 3     Cancer/Testis Antigen Family 5, Member 12
CT5.11 2 3     Protein SSX12
Cancer/Testis Antigen 5.12 3     Sarcoma, Synovial, X-Chromosome-Related 12
SSRC2 5     

External Ids:    HGNC: 113351   Entrez Gene: 67562   Ensembl: ENSG000001267527   OMIM: 3128205   UniProtKB: Q163843   

Export aliases for SSX1 gene to outside databases

Previous GC identifers: GC0XP046917 GC0XP046332 GC0XP046794 GC0XP047160 GC0XP047871 GC0XP047999 GC0XP047958 GC0XP045828


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SSX1:
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These
proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and
cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based
immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in
all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on
chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for
transforming activity. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: SSX1_HUMAN, Q16384
Function: Could act as a modulator of transcription

Gene Wiki entry for SSX1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.1  NT_079573.4  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SSX1 gene promoter:
         HOXA9   HOXA9B   ATF-2   FOXD3   POU3F2   CRE-BP1   Sox9   Meis-1a   Meis-1   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSSX1 promoter sequence
   Search SABiosciences Chromatin IP Primers for SSX1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SSX1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp11.23   Ensembl cytogenetic band:  Xp11.23   HGNC cytogenetic band: Xp11.23

SSX1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SSX1 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP048114:  view genomic region     (about GC identifiers)

Start:
48,114,752 bp from pter      End:
48,126,879 bp from pter
Size:
12,128 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SSX1_HUMAN, Q16384 (See protein sequence)
Recommended Name: Protein SSX1  
Size: 188 amino acids; 21931 Da
Secondary accessions: A3KN76 Q08AJ2 Q5JQ64

Explore the universe of human proteins at neXtProt for SSX1: NX_Q16384

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q16384

  • SSX1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_005626.1  
    ENSEMBL proteins: 
     ENSP00000366118  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: SSX1
    OriGene Protein Over-expression Lysate: SSX1
    OriGene Custom Protein Services for SSX1 
    GenScript Custom Purified and Recombinant Proteins Services for SSX1
    Novus Biologicals SSX1 Proteins
    Novus Biologicals SSX1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SSX1

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--


    SSX1 for ontologies           About GeneDecksing



    SSX1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies (see all 7): SSX1
    OriGene Custom Antibody Services for SSX1 
    GenScript Custom Superior Antibodies Services for SSX1
    Novus Biologicals SSX1 Antibodies
    Search for Antibodies for SSX1 at Abcam  
    Uscn Antibodies for SSX1
    Search ThermoFisher Antibodies for SSX1

    Assay Products for SSX1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SSX1
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for SSX1


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    SSX1 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR003655 Krueppel-associated_box-rel
     IPR019041 SSXRD_motif
     IPR001909 Krueppel-associated_box

    Graphical View of Domain Structure for InterPro Entry Q16384

    ProtoNet protein and cluster: Q16384

    1 Blocks protein family: IPB001909 KRAB box

    UniProtKB/Swiss-Prot: SSX1_HUMAN, Q16384
    Similarity: Belongs to the SSX family
    Similarity: Contains 1 KRAB-related domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: SSX1_HUMAN, Q16384
    Function: Could act as a modulator of transcription

         Genatlas biochemistry entry for SSX1:
    protein SSX1 with homology to Kruppel associated box,KRAB,transcriptional corepressor,complexing with polycomb group
    (PcG) proteins RING1 or BMI1 and associating with chromatin,fused with SYT (SSXT) in synovial sarcoma with
    translocation t(X;18)(p11.2;q11.2) (see BSSX)

    miRNA
    Products:
        
    Browse 3'-UTR reporter clones for miRNA target validation
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SSX1
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate SSX1:
    hsa-miR-199b-3p hsa-miR-199a-3p hsa-miR-3129-5p hsa-miR-512-3p
    SwitchGear 3'UTR luciferase reporter plasmidSSX1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SSX1 (see all 4)
    OriGene shRNA RFP: SSX1
    OriGene siRNA: SSX1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SSX1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SSX1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SSX1 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SSX1
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: SSX1 (NM_005635)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SSX1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SSX1 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SSX1
    Search LifeMap BioReagents cell lines for SSX1

    In Situ Assay
    Products:
       

     
    Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for SSX1

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding IEA--
    GO:0003714transcription corepressor activity TAS10072425


    SSX1 for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SSX1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for SSX1 (Q163843 ENSP000003661184) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LHX4Q969G23, ENSP000002637264I2D: score=1 STRING: ENSP00000263726
    FUBP3Q96I243, ENSP000003181774I2D: score=1 STRING: ENSP00000318177
    SNAI1O958633I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--


    SSX1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SSX1
    Search CenterWatch for drugs/clinical trials and news about SSX1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SSX1 gene: 
    NM_005635.2  

    Unigene Cluster for SSX1:

    Synovial sarcoma, X breakpoint 1
    Hs.434142  [show with all ESTs]
    Unigene Representative Sequence: NM_005635
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000376919(uc004djb.1)

    miRNA
    Products:
         
    Browse 3'-UTR reporter clones for miRNA target validation
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SSX1
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate SSX1:
    hsa-miR-199b-3p hsa-miR-199a-3p hsa-miR-3129-5p hsa-miR-512-3p
    SwitchGear 3'UTR luciferase reporter plasmidSSX1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SSX1 (see all 4)
    OriGene shRNA RFP: SSX1
    OriGene siRNA: SSX1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SSX1
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SSX1 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SSX1
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: SSX1 (NM_005635)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SSX1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SSX1 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SSX1
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat SSX1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SSX1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SSX1

    Additional cDNA sequence: 

    BC001003.2 BC125151.1 BC128611.1 BC133693.1 BC150487.2 X86174.1 

    3 DOTS entries:

    DT.40315656  DT.92450035  DT.92450031 

    24/30 AceView cDNA sequences (see all 30):

    AA954482 BE535379 BE408883 BU170242 NM_005635 BC001003 AA378285 BE277023 
    BQ434972 CB160731 X86174 BQ432374 BQ229996 BF211314 BQ774004 BE410950 
    AW951509 BQ224117 BQ774650 BI831262 BP428754 BE777476 BU619846 BU178412 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SSX1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See SSX1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SSX1

    SOURCE GeneReport for Unigene cluster: Hs.434142

    UniProtKB/Swiss-Prot: SSX1_HUMAN, Q16384
    Tissue specificity: Expressed at high level in the testis. Expressed at low level in thyroid. Not detected in tonsil,
    colon, lung, spleen, prostate, kidney, striated and smooth muscles. Detected in rhabdomyosarcoma and fibrosarcoma cell
    lines. Not detected in mesenchymal and epithelial cell lines

        SABiosciences Custom PCR Arrays for SSX1
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SSX1
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat SSX1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SSX1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SSX1
    In Situ
    Assay Products:
     

     
    Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for SSX1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
      --

    ENSEMBL Gene Tree for SSX1 (if available)
    TreeFam Gene Tree for SSX1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SSX1 gene
    SSX2B2  SSX22  SSX62  SSX42  SSX72  SSX52  SSX92  SSX4B2  
    SSX32  
    15 SIMAP similar genes for SSX1 using alignment to 1 protein entry:     SSX1_HUMAN:
    SYT-SSX1    SSX8    SSX6    SYT-SSX2    SSX5    SSX4B
    SSX2B    SSX7    SSX3    SSX11    SSX9    SSX4
    SSX2    SSX10    PRDM9

    SSX1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/266 NCBI SNPs in SSX1 are shown (see all 266    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1901351691,2
    --48112878(+) CCTGCC/TGACAA 1 -- us2k10--------
    rs78846411,2
    C,F,A,H,--48112975(+) TTTGCG/AGTAAT 1 -- us2k16Minor allele frequency- A:0.45NS EA NA 305
    rs43132831,2
    C,F,A,H,--48113082(+) AACAAG/ATAGTC 1 -- us2k14Minor allele frequency- A:0.45NA 11
    rs45001951,2
    C,F,A,H,--48113222(+) TCAGCG/AGGGAC 1 -- us2k12Minor allele frequency- A:0.50NA 4
    rs354380321,2
    C,--48113250(+) AAAAA-/ATTATT 1 -- us2k10--------
    rs1824101341,2
    --48113389(+) CTCTTA/GAGCCT 1 -- us2k10--------
    rs1852635461,2
    --48113661(+) ATGAGC/TTCCCT 1 -- us2k10--------
    rs1924829061,2
    --48113698(+) TACTCA/TTTTTA 1 -- us2k10--------
    rs1838709811,2
    --48113800(+) AAGTGG/TTTTTT 1 -- us2k10--------
    rs1888863651,2
    --48113830(+) TAAAAA/TTTTTT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SSX1 (48114752 - 48126879 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 7 variations for SSX1
         7 CNVs: 96641 83494 8304 4149 67975 67974 7789
    Locus Specific Mutation Databases (LSDB): SSX1

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SSX1
    DNA2.0 Custom Variant and Variant Library Synthesis for SSX1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    SSX1 for disorders           About GeneDecksing

    OMIM gene information: 312820    OMIM disorders: --

    UniProtKB/Swiss-Prot: SSX1_HUMAN, Q16384
  • Note=A chromosomal aberration involving SSX1 may be a cause of synovial sarcoma. Translocation
  • t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion
    products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of
    the breakpoint can occur (low frequency)

    13 diseases for SSX1:    About MalaCards
    synovial sarcoma    sarcoma    extraskeletal mesenchymal chondrosarcoma    tonsillitis
    fibrosarcoma    rhabdomyosarcoma    hepatocellular carcinoma    melanoma
    lung cancer    thyroiditis    adenocarcinoma    carcinoma
    prostatitis

    2 diseases from the University of Copenhagen DISEASES database for SSX1:
    Synovial sarcoma     Sarcoma

    4 Novoseek disease relationships for SSX1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    sarcoma synovial 93.8 23 7539744 (2), 10404078 (1), 17197895 (1), 17186289 (1) (see all 18)
    sarcoma 62.2 2 10399965 (1), 12469233 (1)
    melanoma 25.6 2 12007189 (1), 9378559 (1)
    cancer 0 2 17186289 (1), 15603546 (1)

    Human Genome Epidemiology (HuGE) Navigator: SSX1 (1 document)

    Export disorders for SSX1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SSX1 gene, integrated from 9 sources (see all 51):
    (articles sorted by number of sources associating them with SSX1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of two alternative fusion genes, SYT-SSX1 and SYT- SSX2, in t(X;18)(p11.2;q11.2)-positive synovial sarcomas. (PubMed id 7655467)1, 2, 3 de Leeuw B.... Geurts van Kessel A. (1995)
    2. Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma. (PubMed id 7539744)1, 2, 9 Crew A.J.... Cooper C.S. (1995)
    3. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP. (PubMed id 12007189)1, 9 de Bruijn D.R.H....van Kessel A.G. (2002)
    6. Functional domains of the SYT and SYT-SSX synovial sarcoma translocation proteins and co-localization with the SNF protein BRM in the nucleus. (PubMed id 10072425)1, 9 Thaete C....Goodwin G. (1999)
    7. An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (2010)
    8. Downregulation of SS18-SSX1 expression in synovial sa rcoma by small interfering RNA enhances the focal adhesion pathway and inhibits anchorage-independent growth in vitro and tumor growth in vivo. (PubMed id 20198325)1 Takenaka S....Itoh K. (2010)
    9. Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease. (PubMed id 19204726)1 Chapuis J....Lambert J.C. (2009)
    10. Comparisons for detecting NY-ESO-1 mRNA expression levels in hepatocellular carcinoma tissues. (PubMed id 19212631)1 Wang X.Y....Cai J. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6756 HGNC: 11335 AceView: SSX1 Ensembl:ENSG00000126752 euGenes: HUgn6756
    ECgene: SSX1 H-InvDB: SSX1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SSX1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for SSX1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SSX1 gene:
    Search GeneIP for patents involving SSX1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     OriGene Antibodies for SSX1   OriGene shRNA RFP for SSX1  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SSX1   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SSX1  
     OriGene Protein Over-expression Lysate for SSX1   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for SSX1   Browse 3'-UTR reporter clones for miRNA target validation  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SSX1   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SSX1  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     OriGene Purified Protein for SSX1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SSX1   OriGene Custom Protein Services for SSX1  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SSX1
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SSX1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SSX1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SSX1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SSX1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SSX1
     GenScript Custom Purified and Recombinant Proteins Services for SSX1 GenScript cDNA clones with any tag delivered in your preferred vector for SSX1
     GenScript Custom Assay Services for SSX1 GenScript Custom Superior Antibodies Services for SSX1
     GenScript Custom overexpressing Cell Line Services for SSX1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in SSX1 promoter
     Search Chromatin IP Primers for SSX1
     RT2 qPCR Primer Assay in human, mouse / rat SSX1
     Search GNC Networks for SSX1
     SABiosciences Custom PCR Arrays for SSX1
     Search Tocris compounds for SSX1
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     SSX1 antibodies
     SSX1 proteins
     SSX1 lysates
     Search for Antibodies for SSX1 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for SSX1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     SSX1 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for SSX1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for SSX1
     SwitchGear 3'UTR luciferase reporter plasmids for SSX1
     SwitchGear Promoter luciferase reporter plasmids for SSX1
     Search ThermoFisher Antibodies for SSX1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SSX1
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      SSX1 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4