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Aliases for SSUH2 Gene

Aliases for SSUH2 Gene

  • Ssu-2 Homolog (C. Elegans) 2 3 5
  • Protein Ssu-2 Homolog 3 4
  • C3orf32 3 4
  • Chromosome 3 Open Reading Frame 32 2
  • Fls485 3
  • SSU-2 3

External Ids for SSUH2 Gene

Previous HGNC Symbols for SSUH2 Gene

  • C3orf32

Summaries for SSUH2 Gene

GeneCards Summary for SSUH2 Gene

SSUH2 (Ssu-2 Homolog (C. Elegans)) is a Protein Coding gene. GO annotations related to this gene include unfolded protein binding and heat shock protein binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SSUH2 Gene

Genomics for SSUH2 Gene

Regulatory Elements for SSUH2 Gene

Enhancers for SSUH2 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around SSUH2 on UCSC Golden Path with GeneCards custom track

Genomic Location for SSUH2 Gene

8,590,122 bp from pter
8,745,040 bp from pter
154,919 bases
Minus strand

Genomic View for SSUH2 Gene

Genes around SSUH2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SSUH2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SSUH2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SSUH2 Gene

Proteins for SSUH2 Gene

  • Protein details for SSUH2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein SSUH2 homolog
    Protein Accession:
    Secondary Accessions:
    • A6NFA9
    • B3KS84
    • B7Z6E3
    • F5H2S5
    • Q7Z7K4

    Protein attributes for SSUH2 Gene

    353 amino acids
    Molecular mass:
    39845 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH52614.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for SSUH2 Gene


neXtProt entry for SSUH2 Gene

Proteomics data for SSUH2 Gene at MOPED

Post-translational modifications for SSUH2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for SSUH2 Gene

Domains & Families for SSUH2 Gene

Protein Domains for SSUH2 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SSUH2: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SSUH2 Gene

Function for SSUH2 Gene

Molecular function for SSUH2 Gene

UniProtKB/Swiss-Prot Induction:
Induced during epithelial differentiation.
genes like me logo Genes that share phenotypes with SSUH2: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SSUH2 Gene

Localization for SSUH2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SSUH2 Gene


Subcellular locations from

Jensen Localization Image for SSUH2 Gene COMPARTMENTS Subcellular localization image for SSUH2 gene
Compartment Confidence
golgi apparatus 2
mitochondrion 2
cytosol 1
nucleus 1
peroxisome 1

No data available for Gene Ontology (GO) - Cellular Components for SSUH2 Gene

Pathways & Interactions for SSUH2 Gene

SuperPathways for SSUH2 Gene

No Data Available

Interacting Proteins for SSUH2 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: Q9Y2M2-SSUH2_HUMAN ENSP00000324551 for SSUH2 Gene via MINT STRING

Gene Ontology (GO) - Biological Process for SSUH2 Gene


No data available for Pathways by source and SIGNOR curated interactions for SSUH2 Gene

Drugs & Compounds for SSUH2 Gene

No Compound Related Data Available

Transcripts for SSUH2 Gene

Unigene Clusters for SSUH2 Gene

Ssu-2 homolog (C. elegans):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SSUH2 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b · 12c ^ 13 ^ 14 ^ 15a · 15b ^ 16a · 16b · 16c ·
SP1: - - - - - - - -
SP2: - - - - -
SP3: - - - - - - - - - -
SP4: - - - - - - - - -
SP6: - - - -

ExUns: 16d

Relevant External Links for SSUH2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SSUH2 Gene

mRNA expression in normal human tissues for SSUH2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SSUH2 Gene

This gene is overexpressed in Testis (x16.9) and Small Intestine - Terminal Ileum (x6.2).

Protein differential expression in normal tissues from HIPED for SSUH2 Gene

This gene is overexpressed in NK cells (42.8) and CD4 Tcells (24.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for SSUH2 Gene

SOURCE GeneReport for Unigene cluster for SSUH2 Gene Hs.740735

mRNA Expression by UniProt/SwissProt for SSUH2 Gene

Tissue specificity: Expressed in enterocytes of small and large intestinal mucosa (at protein level). Expressed in enterocytes, chromaffine and interstitial cells.
genes like me logo Genes that share expression patterns with SSUH2: view

Protein tissue co-expression partners for SSUH2 Gene

Primer Products

Orthologs for SSUH2 Gene

This gene was present in the common ancestor of animals.

Orthologs for SSUH2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C22H3orf32 35
  • 83.82 (n)
  • 85.07 (a)
SSUH2 36
  • 86 (a)
(Canis familiaris)
Mammalia SSUH2 35
  • 88.36 (n)
  • 88.27 (a)
SSUH2 36
  • 75 (a)
(Mus musculus)
Mammalia Ssu2 35
  • 81.65 (n)
  • 81.65 (a)
Ssu2 16
Ssu2 36
  • 79 (a)
(Pan troglodytes)
Mammalia SSUH2 35
  • 94.46 (n)
  • 92.71 (a)
SSUH2 36
  • 88 (a)
(Rattus norvegicus)
Mammalia Ssuh2 35
  • 82.09 (n)
  • 81.82 (a)
(Monodelphis domestica)
Mammalia SSUH2 36
  • 74 (a)
(Ornithorhynchus anatinus)
Mammalia SSUH2 36
  • 68 (a)
(Anolis carolinensis)
Reptilia SSUH2 36
  • 63 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ssuh2 35
  • 48.81 (n)
  • 39.83 (a)
(Danio rerio)
Actinopterygii LOC101882914 35
  • 52.85 (n)
  • 45.38 (a)
SSUH2 36
  • 48 (a)
(Caenorhabditis elegans)
Secernentea ssu-2 36
  • 22 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 27 (a)
Species with no ortholog for SSUH2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SSUH2 Gene

Gene Tree for SSUH2 (if available)
Gene Tree for SSUH2 (if available)

Paralogs for SSUH2 Gene

No data available for Paralogs for SSUH2 Gene

Variants for SSUH2 Gene

Sequence variations from dbSNP and Humsavar for SSUH2 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs2276800 - 8,633,853(-) TGGCC(A/C/T)GCGTG intron-variant, nc-transcript-variant, reference, missense
rs16805 -- 8,597,105(+) CCAGC(C/T)GTGAG intron-variant
rs48221 -- 8,606,381(+) ATTCA(C/T)ATTCA intron-variant
rs84141 -- 8,646,649(+) CGTAC(A/G)GAAGT intron-variant, upstream-variant-2KB
rs125698 -- 8,663,540(+) TCGGG(G/T)TCAGG intron-variant

Variation tolerance for SSUH2 Gene

Residual Variation Intolerance Score: 81.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.95; 59.73% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for SSUH2 Gene

Disorders for SSUH2 Gene

Relevant External Links for SSUH2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SSUH2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SSUH2 Gene

Publications for SSUH2 Gene

  1. Small intestinal mucosa expression of putative chaperone fls485. (PMID: 20205943) Reinartz A. … Gassler N. (BMC Gastroenterol. 2010) 2 3 4 67
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for SSUH2 Gene

Sources for SSUH2 Gene