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SSTR1 Gene

protein-coding GIFtS: 63

GC14P037746

somatostatin receptor 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
SRIF-2 ^², ³
SS1R ^³

Descriptions
G-protein coupled receptor ^²
somatostatin receptor 1 ^²

External Ids
HGNC: 11330¹
Entrez Gene: 6751²
UniProtKB: P30872³
Ensembl: ENSG00000139874⁷

Search outside databases for aliases for SSTR1 gene

Previous GC identifers: GC14P036059 GC14P032534 GC14P036668 GC14P036667

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for SSTR1:

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory

proteins. The biological effects of somatostatin are probably mediated by a family of G

protein-coupled receptors that are expressed in a tissue-specific manner. The encoded protein is a

member of the superfamily of somatostatin receptors having seven transmembrane segments, and is

expressed in highest levels in jejunum and stomach. [provided by RefSeq]

UniProtKB/Swiss-Prot: SSR1_HUMAN, P30872

Function: Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This

receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In

addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin

insensitive G proteins

Gene Wiki entry for SSTR1 (Somatostatin_receptor_1)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the SSTR1 gene

Entrez Gene cytogenetic band: 14q13 Ensembl cytogenetic band: 14q21.1 HGNC cytogenetic band: 14q13

SSTR1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 14 GeneLoc Exon Structure

GeneLoc location for GC14P037746: (about GC identifiers)

Start:	37,746,955 bp from pter
End:	37,752,019 bp from pter
Size:	5,065 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000014.7 NT_026437.11

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: SSR1_HUMAN, P30872 (See protein sequence)

Recommended Name: Somatostatin receptor type 1

Size: 391 amino acids; 42686 Da

Subunit: Interacts with SKB1

Subcellular location: Cell membrane; Multi-pass membrane protein

REFSEQ proteins: NP_001040.1

ENSEMBL proteins:

ENSP00000379570 ENSP00000267377

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Somatostatin Receptor 1)
	Human Recombinant Proteins from Abnova (SSTR1)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005624	membrane fraction	IEA	--
GO:0005886	plasma membrane	TAS	1346068
GO:0005887	integral to plasma membrane	TAS	1346068

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Antibodies for SSTR1:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of SSTR1
	Sigma-Aldrich Antibodies for SSTR1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (Somatostatin Receptor 1), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (SSTR1)
	Novus Biologicals Antibodies for SSTR1

Assays for SSTR1:

	Invitrogen Assays for SSTR1
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P30872

ProtoNet protein and cluster: P30872

2 Blocks protein families:

IPB000586 Somatostatin receptor signature

IPB001116 Somatostatin receptor type 1 signature

UniProtKB/Swiss-Prot: SSR1_HUMAN, P30872

Similarity: Belongs to the G-protein coupled receptor 1 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (SSTR1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (SSTR1)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): BC035618

Applied Biosystems Silencer® siRNAs for SSTR1

Sigma-Aldrich siRNA and siRNA Panels for SSTR1

Sigma-Aldrich shRNA Panels and shRNA for SSTR1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for SSTR1
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_001049
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001049
untagged cDNA clones in CMV expression vector (see all 2): BC035618

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: BC035618

UniProtKB/Swiss-Prot: SSR1_HUMAN, P30872

Function: Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This

receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In

addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin

insensitive G proteins

Genatlas biochemistry entry for SSTR1:

somatostatin receptor gene 1,G protein coupled receptor superfamily

4 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Sstr1):

behavior/neurological

homeostasis/metabolism

nervous system

vision/eye

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004872	receptor activity	IEA	--
GO:0004930	G-protein coupled receptor activity	IEA	--
GO:0004994	somatostatin receptor activity	IDA	1346068

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for SSTR1

5/11 Interacting proteins for SSTR1 (ENSP00000267377³) via UniProtKB, MINT, and/or STRING (see all 11 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SST	ENSP00000287641³	STRING (score=.999)
APITD1	ENSP00000317110³	STRING (score=.976)
SSTR5	ENSP00000293897³	STRING (score=.963)
SSTR3	ENSP00000330138³	STRING (score=.906)
SSTR2	ENSP00000350198³	STRING (score=.905)

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5/7 Gene Ontology (GO) biological process terms (links to tree view) (see all 7 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007187	G-protein signaling, coupled to cyclic nucleotide second messenger	TAS	8405411
GO:0007215	glutamate signaling pathway	IEA	--
GO:0007218	neuropeptide signaling pathway	IEA	--
GO:0007267	cell-cell signaling	TAS	1346068
GO:0007584	response to nutrient	TAS	1346068

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Sigma-Aldrich Small Molecules for SSTR1:

Antagonist

Compounds for SSTR1 available from Tocris Bioscience

Compound	Action	CAS number
Somatostatin	Influences growth hormone release	[51110-01-1]
RC 160	Somatostatin analog	[103222-11-3]
Cyclosomatostatin	Non-selective sst receptor antagonist	[84211-54-1]

About this table

9 Novoseek chemical compound relationships for SSTR1 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
111in-pentetreotide	64.60	1	15801004 (1)
ribonucleic acid	40.10	1	10902809 (1)
guanosine 5'-o-(3-thiotriphosphate)	31.12	1	8145728 (1)
phosphotyrosine	28.03	3	7854346 (2), 11088001 (1)
tyrosine	19.77	10	7907795 (2), 9892010 (1), 18951121 (1), 8786539 (1) (see all 5)
threonine	13.99	2	9892010 (1), 11088001 (1)
cyclic amp	7.67	1	8145728 (1)
glucose	4.89	3	16406265 (2)
calcium	0.00	2	7878022 (1), 7674817 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (SSTR1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (SSTR1)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): BC035618

Sigma-Aldrich siRNA and siRNA Panels for SSTR1

Sigma-Aldrich shRNA Panels and shRNA for SSTR1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001049

REFSEQ mRNAs for SSTR1 gene:

NM_001049.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001049

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001049
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001049
                                 untagged cDNA clones in CMV expression vector (see all 2): BC035618

Additional cDNA sequence:

AK290868.1 BC035618.1 BX248780.1

1 DOTS entry:

DT.205737

24/48 AceView cDNA sequences (see all 48 ):

CK821227 BX280512 AA350521 BU071007 BU070951 CK821228 NM_001049 BI789177

BC035618 BX248780 AA889113 BU071151 BF876598 F13186 BF878834 AW163607

BI962657 BU072963 F11022 AI129156 BI753905 AW051270 BX372173 R52599

highest scoring ESTs for SSTR1:

AI129156 T65201 AA350521 AA889113 AA977679 AI815754 AW051270 AW162959 AW163607 AW954584

Unigene Cluster for SSTR1:

Somatostatin receptor 1

Hs.248160 [show with all ESTs]

Unigene Representative Sequence: NM_001049

GeneLoc Exon Structure

2 Ensembl transcripts including schematic representations:

ENST00000396273 ENST00000267377

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

SSTR1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for SSTR1

¹ / ² / ³

6 probe-sets matching SSTR1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
84092_at²^{, 3}	U95-E	1	1.00	1.00	0.63	1.22	T65201	1.00	1.00	1.00	1
73968_at²^{, 3}	U95-E	1	1.00	1.00	0.98	0.79	AI129156	1.00	1.00	1.00	1
208482_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_001049	0.60	1.00	0.82	1
235591_at²^{, 3}	U133-B	1	1.00	1.00	--	--	R62424	0.80	1.00	0.91	1
208482_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
235591_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks SSTR1 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: ATATACAATG

SOURCE GeneReport for Unigene cluster: Hs.248160
UniProtKB/Swiss-Prot: SSR1_HUMAN, P30872
Tissue specificity: Fetal kidney, fetal liver, and adult pancreas, brain, lung, jejunum and stomach

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for SSTR1 gene from 5/9 species (see all 9 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	SSTR1¹	--	somatostatin receptor 1	93.16(n) 100(a)	403455 XM_537417.2 XP_537417.1
chimpanzee (Pan troglodytes)	SSTR1¹	--	somatostatin receptor 1	99.57(n) 100(a)	467434 XM_522831.2 XP_522831.1
cow (Bos taurus)	SSTR1¹	--	somatostatin receptor 1	93.5(n) 100(a)	540013 XM_001250796.1 XP_001250797.1
rat (Rattus norvegicus)	Sstr1¹	--	somatostatin receptor 1	89.68(n) 97.44(a)	25033 NM_012719.1 NP_036851.1
mouse (Mus musculus)	Sstr1^{1, 5}	12 (23.00 cM)⁵	somatostatin receptor 1^{1, 5}	89.26(n)¹ 98.72(a)¹	20605¹ NM_009216.3¹ NP_033242.1¹ AK046464⁵ BC140315⁵ (see all 6)

About this table Species with no ortholog for SSTR1

ENSEMBL Gene Tree for SSTR1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for SSTR1 gene

SSTR3² SSTR5² SSTR2² SSTR4²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/53 NCBI SNPs in SSTR1 are shown (see all 53 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 54)

AB	SNP ID	Valid	Chr 14 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs4640088^1,2	A,C,F,H	37752444(+)	`ACAACG/AGAAGG`	1	--	ng3¹		12		EU EA WA NA	1040
	rs4073845^1,2	C,F,H	37747403(+)	`GCTTAG/TGGCCA`	1	--	ut5¹		12		EU EA WA NA CSAM	936
	rs12437095^1,2	A,C,F	37748107(+)	`TCCACG/AGTCGC`	1	--	ut5¹ ese³		5		NA EU CSAM EA	380
	rs12889916^1,2	C,F,H	37749831(+)	`TTCCCT/CACCCT`	1	--	ut3¹ ese³		9		NA EU CSAM EA WA	782
	rs4143959^1,2	C,F,H	37751020(+)	`TCTTAC/TTATAG`	1	--	ut3¹ ese³		17		NA EU CSAM EA WA	1632
	rs1135473^1,2	C,F,H	37750864(+)	`GGGCGG/AGCATG`	1	--	ut3¹ ese³		10		MN NA EU CSAM EA WA	978
	rs1135474^1,2	C,F,H	37750977(+)	`TTTTTG/CATTGT`	1	--	ut3¹		14		MN NA EU CSAM EA WA	1402
--	rs2803939^1,2	A,C	37745644(-)	`AATGCC/TTTTTA`	1	--	ng5¹ tfbs³		0	--	--	--	--
	rs33974002^1,2	C,F	37750399(+)	`TTCAAA/GGACCA`	1	--	ut3¹		5		NA EU CSAM EA	380
--	rs12434340^1,2	C,F	37748243(+)	`GGCTGC/G/TGGGCT`	1	--	ut5¹ ese³		5		NA EU CSAM EA	380

About this table

HapMap Linkage Disequilibrium images for SSTR1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 182451

10/24 Novoseek disease relationships for SSTR1 gene (see all 24 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
pituitary adenoma nonfunctioning	72.21	2	15472224 (1)
prolactinoma	66.05	6	10487698 (2), 18426817 (2), 8106629 (1), 16625843 (1)
pituitary adenoma	65.52	7	12788890 (2), 8866248 (1), 17473207 (1), 12721506 (1) (see all 5)
pituitary tumors	59.47	9	15103227 (4), 7530798 (1), 16379036 (1), 8106629 (1)
carcinoid	57.25	3	8132773 (1), 16508627 (1), 8653698 (1)
insulinoma	55.05	5	8132773 (1), 12181718 (1), 11772967 (1), 10866997 (1)
thyroid carcinoma medullary	53.95	4	15077916 (1), 11344221 (1), 12359227 (1)
acromegaly	46.04	1	15103227 (1)
adenoma	44.44	11	12788890 (2), 17420609 (2), 10690891 (1), 12721506 (1) (see all 5)
tumors	43.73	49	18823376 (3), 7530798 (2), 8012966 (2), 8515684 (2) (see all 26)

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Genetic Association Database: SSTR1
Human Genome Epidemiology Navigator: SSTR1 (3 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/159 PubMed articles for SSTR1 gene (see all 159 ):

Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney. (PubMed id 1346068)^{1, 3, 4} Yamada Y.... Seino S. (1992)
Interaction of the somatostatin receptor subtype 1 with the human homolog of the Shk1 kinase-binding protein from yeast. (PubMed id 10734105)^{1, 3, 4} Schwaerzler A.... Richter D. (2000)
Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms. (PubMed id 8449518)^{1, 2, 3} Yamada Y....Bell G.I. (1993)
Genetic variation in the growth hormone synthesis pathway in relation to circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3, and breast cancer risk: results from the European prospective investigation into cancer and nutrition study. (PubMed id 16214911)^{3, 6} Canzian F....Kaaks R. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Somatostatin receptor-1 induces cell cycle arrest and inhibits tumor growth in pancreatic cancer. (PubMed id 18823376)^{1, 3} Li M....Fisher W.E. (2008)
Somatostatin receptor subtype 1 selective activation in human growth hormone (GH)- and prolactin (PRL)-secreting pituitary adenomas: effects on cell viability, GH, and PRL secretion. (PubMed id 12788890)^{1, 3} Zatelli M.C....degli Uberti E.C. (2003)
Subtype-selective expression of the five somatostatin receptors (hSSTR1-5) in human pancreatic islet cells: a quantitative double-label immunohistochemical analysis. (PubMed id 9892225)^{1, 3} Kumar U....Patel Y.C. (1999)
Somatostatin receptor gene expression in human ocular tissues: RT-PCR and immunohistochemical study. (PubMed id 11527930)^{1, 3} Klisovic D.D....Lubow M. (2001)
Gene expression of somatostatin receptor subtypes, SSTR1 and SSTR2, in human lung cancer cell lines. (PubMed id 7968260)^{1, 3} Fujita T....Takahara J. (1994)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 6751	HGNC: 11330	AceView: SSTR1	Ensembl:ENSG00000139874	euGenes: HUgn6751
ECgene: SSTR1	H-InvDB: SSTR1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for SSTR1	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for SSTR1
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for SSTR1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for SSTR1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for SSTR1		Antibodies for SSTR1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for SSTR1		Small molecules for SSTR1
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (SSTR1)
	Antibodies (SSTR1)
	Chimera RNAi (SSTR1)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (Somatostatin Receptor 1)
	Antibodies (Somatostatin Receptor 1)

Search OriGene for SSTR1

Tocris compounds for SSTR1

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for SSTR1

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SSTR1 Gene

protein-coding GIFtS: 63

Aliases &
Descriptions
for SSTR1

Summaries
for SSTR1

Genomic Location
for SSTR1

Proteins
for SSTR1

Protein Domains/
Families
for SSTR1

Gene Function
for SSTR1

Pathways & Interactions
for SSTR1

Drugs & Compounds
for SSTR1

Transcripts
for SSTR1

Expression
for SSTR1

Orthologs
for SSTR1

Paralogs
for SSTR1

SNPs/Variants
for SSTR1

Disorders & Mutations
for SSTR1

Medical News
for SSTR1

Publications
for SSTR1

Search for SSTR1

Genome Databases showing SSTR1

Other Databases showing SSTR1

Specialized Databases showing SSTR1

Licensable Technologies
for SSTR1

Services
for SSTR1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

SSTR1 Gene

protein-coding GIFtS: 63

Aliases & Descriptionsfor SSTR1

Summariesfor SSTR1

Genomic Locationfor SSTR1

Proteinsfor SSTR1

Protein Domains/Familiesfor SSTR1

Gene Functionfor SSTR1

Pathways & Interactionsfor SSTR1

Drugs & Compoundsfor SSTR1

Transcriptsfor SSTR1

Expression for SSTR1

Orthologsfor SSTR1

Paralogsfor SSTR1

SNPs/Variantsfor SSTR1

Disorders & Mutationsfor SSTR1

Medical Newsfor SSTR1

Publicationsfor SSTR1

Search for SSTR1

Genome Databases showing SSTR1

Other Databases showing SSTR1

Specialized Databases showing SSTR1

Licensable Technologiesfor SSTR1

Servicesfor SSTR1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for SSTR1

Summaries
for SSTR1

Genomic Location
for SSTR1

Proteins
for SSTR1

Protein Domains/
Families
for SSTR1

Gene Function
for SSTR1

Pathways & Interactions
for SSTR1

Drugs & Compounds
for SSTR1

Transcripts
for SSTR1

Expression
for SSTR1

Orthologs
for SSTR1

Paralogs
for SSTR1

SNPs/Variants
for SSTR1

Disorders & Mutations
for SSTR1

Medical News
for SSTR1

Publications
for SSTR1

Licensable Technologies
for SSTR1

Services
for SSTR1