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SST Gene

protein-coding GIFtS: 60

GC03M188869

somatostatin
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
SMST ^¹, ²
somatostatin ^²
somatostatin-14 ^²
somatostatin-28 ^²

Descriptions
Growth hormone release-inhibiting factor ^³

External Ids
HGNC: 11329¹
Entrez Gene: 6750²
UniProtKB: P61278³
Ensembl: ENSG00000157005⁷

Search outside databases for aliases for SST gene

Previous GC identifers: GC03M184201 GC03M188648 GC03M188788 GC03M188707

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for SST:

The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage

of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body

and inhibits the release of numerous secondary hormones by binding to high-affinity

G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine

system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and

most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission

in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by

RefSeq]

UniProtKB/Swiss-Prot: SMS_HUMAN, P61278

Function: Somatostatin inhibits the release of somatotropin

Gene Wiki entry for SST (Somatostatin)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the SST gene

Entrez Gene cytogenetic band: 3q28 Ensembl cytogenetic band: 3q27.3 HGNC cytogenetic band: 3q28

SST Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 3 GeneLoc Exon Structure

GeneLoc location for GC03M188869: (about GC identifiers)

Start:	188,869,388 bp from pter
End:	188,870,895 bp from pter
Size:	1,508 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000003.10 NT_005612.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: SMS_HUMAN, P61278 (See protein sequence)

Recommended Name: Somatostatin precursor

Size: 116 amino acids; 12736 Da

Subcellular location: Secreted

PDB structures from and Proteopedia :

1P2W (3D)

Secondary accessions: P01166

REFSEQ proteins: NP_001039.1

ENSEMBL proteins:

ENSP00000287641

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Somatostatin 14, Somatostatin 28, Somatostatin)
	Human Recombinant Proteins from Abnova (SST)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--
GO:0005615	extracellular space	TAS	9437026

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Antibodies for SST:

	Invitrogen Antibodies for SST
	Millipore Mono- and Polyclonal Antibodies for the study of SST
	Sigma-Aldrich Antibodies for SST
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (Somatostatin 14, Somatostatin 28, Somatostatin), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (SST)
	Novus Biologicals Antibody for SST

Assays for SST:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P61278

ProtoNet protein and cluster: P61278

UniProtKB/Swiss-Prot: SMS_HUMAN, P61278

Similarity: Belongs to the somatostatin family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (SST)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (SST)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001048

Applied Biosystems Silencer® siRNAs for SST

Sigma-Aldrich siRNA for SST

Sigma-Aldrich shRNA Panels and shRNA for SST

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_001048
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001048
untagged cDNA clone in CMV expression vector: NM_001048

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001048

UniProtKB/Swiss-Prot: SMS_HUMAN, P61278

Function: Somatostatin inhibits the release of somatotropin

Genatlas biochemistry entry for SST:

somatostatin

5 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Sst):

digestive/alimentary

growth/size

homeostasis/metabolism

immune system

nervous system

1 Gene Ontology (GO) molecular function term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005179	hormone activity	TAS	9886848

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

2 Sigma-Aldrich "Your Favorite Gene" Pathways for SST (Your Favorite Gene powered by Ingenuity)

Antiproliferative Role of Somatostatin Receptor 2
Cholecystokinin/Gastrin-mediated Signaling

GeneDecks SST for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for SST

5/98 Interacting proteins for SST (ENSP00000287641³) via UniProtKB, MINT, and/or STRING (see all 98 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SSTR1	ENSP00000267377³	STRING (score=.999)
SSTR2	ENSP00000350198³	STRING (score=.999)
SSTR3	ENSP00000330138³	STRING (score=.999)
SSTR5	ENSP00000293897³	STRING (score=.999)
GCG	ENSP00000364647³	STRING (score=.99)

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5/7 Gene Ontology (GO) biological process terms (links to tree view) (see all 7 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007186	G-protein coupled receptor protein signaling pathway	TAS	8405411
GO:0007268	synaptic transmission	TAS	9437026
GO:0007584	response to nutrient	TAS	6145156
GO:0007586	digestion	TAS	6145156
GO:0008285	negative regulation of cell proliferation	TAS	9886848

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Compounds for SST available from Tocris Bioscience
UniProtKB/Swiss-Prot: SMS_HUMAN, P61278

Pharmaceutical: A synthetic analog known as octreotide or SMS 201-995 is available under the name

Sandostatin (Novartis). It is used for the treatment of a variety of disorders including

acromegaly and the symptomatic treatment of carcinoid tumors and vasoactive intestinal peptide

tumors

10/20 Novoseek chemical compound relationships for SST gene (see all 20 )

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
111in-pentetreotide	91.18	70	7975760 (3), 11787852 (3), 7908220 (2), 8683311 (1) (see all 56)
pegvisomant	88.32	48	17427111 (3), 16498061 (2), 18611977 (2), 19147599 (2) (see all 34)
tyr-3-octreotide	85.45	33	10537142 (5), 10398816 (2), 1975618 (2), 9662587 (1) (see all 19)
pasireotide	83.01	15	18957506 (2), 18041687 (2), 17113654 (1), 19445573 (1) (see all 11)
pentetreotide	80.32	12	8099808 (2), 11952044 (1), 10229898 (1), 9669296 (1) (see all 9)
2-pyrrolinodoxorubicin	76.90	22	10690557 (1), 11290438 (1), 11027415 (1), 11571730 (1) (see all 13)
prosomatostatin	75.48	51	1976560 (5), 8846251 (5), 14614908 (3), 1967585 (2) (see all 15)
ghrp	73.06	27	7738479 (3), 14610296 (3), 12795360 (2), 17686882 (2) (see all 13)
hexarelin	72.22	23	9624598 (3), 7731498 (3), 8799695 (2), 7588427 (2) (see all 15)
pre-prosomatostatin	70.41	10	1968345 (1), 15970377 (1), 8097410 (1), 8621771 (1) (see all 8)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (SST)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (SST)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001048

Sigma-Aldrich siRNA for SST

Sigma-Aldrich shRNA Panels and shRNA for SST

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001048

REFSEQ mRNAs for SST gene:

NM_001048.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001048

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001048
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001048
                                 untagged cDNA clone in CMV expression vector: NM_001048

Additional cDNA sequence:

AK312177.1 BC032625.1

6 DOTS entries:

DT.97806115 DT.100815862 DT.412989 DT.120879761 DT.100815860 DT.100815861

24/365 AceView cDNA sequences (see all 365 ):

BU949387 BU078977 CA866312 BQ271933 CA776482 BU785692 CA841941 BM505285

BM314522 BM765896 BM352863 BU952101 BU785111 CB177931 BM352214 BU074907

BM509691 CB068296 BQ271542 BQ286062 CA775400 BM314215 BU952061 BM311218

highest scoring ESTs for SST:

AI636761 AA084460 AA670289 AI091308 AI347725 AI460386 AI590063 AI656417 AI796391 AW583834

Unigene Cluster for SST:

Somatostatin

Hs.12409 [show with all ESTs]

Unigene Representative Sequence: BI918626

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000287641

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

SST expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for SST

¹ / ² / ³

4 probe-sets matching SST gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
1430_at²^{, 3}	U95-A	1	1.00	1.00	0.99	0.94	J00306	0.20	1.00	0.72	1
37782_at²^{, 3}	U95-A	2	1.00	0.94	0.99	1.07	AI636761	1.00	1.00	1.00	1
213921_at²^{, 3}	U133-A	2	1.00	0.91	--	--	NM_001048	0.60	1.00	0.82	1
213921_at²	U133Plus2	2	1.00	0.91	--	--	--	--	--	--	--

GeneDecks SST for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.12409
Expression variation in blood from EXPOLDB for SST

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for SST gene from 5/10 species (see all 10 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	SST¹	--	somatostatin	95.98(n) 98.28(a)	403993 NM_001003307.1 NP_001003307.1
chimpanzee (Pan troglodytes)	SST¹	--	somatostatin	99.71(n) 99.14(a)	471035 XM_526419.2 XP_526419.1
cow (Bos taurus)	SST¹	--	somatostatin	94.83(n) 98.28(a)	280932 NM_173960.1 NP_776385.1
rat (Rattus norvegicus)	Sst¹	--	somatostatin	90.23(n) 96.55(a)	24797 NM_012659.1 NP_036791.1
mouse (Mus musculus)	Sst^{1, 5}	16 (19.00 cM)⁵	somatostatin^{1, 5}	90.52(n)¹ 96.55(a)¹	20604¹ NM_009215.1¹ NP_033241.1¹ AI326805⁵ AK003014⁵ (see all 7)

About this table Species with no ortholog for SST

ENSEMBL Gene Tree for SST

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/43 NCBI SNPs in SST are shown (see all 43 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 60)

AB	SNP ID	Valid	Chr 3 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs7624906^1,2	A,C,F,H	188872330(+)	`TGTGCT/CTGTAA`	1	--	ng3¹		16	NA EU CSAM EA WA	1296
	rs4988514^1,2	C,F,H	188869525(+)	`TGATAT/CGGACA`	1	--	ut3¹ ese³		14	NA EU CSAM EA WA	1168
	rs3755792^1,2	C,F,H	188872655(+)	`GAAACG/AAGGAT`	1	--	ng3¹		17	EA NA EU CSAM WA	2826
	rs9822131^1,2	C,F,H	188869264(+)	`ATTGCC/TACCGA`	1	--	ng5¹		9	EU EA WA NA CSAM	794
	rs35603672^1,2	C,F	188870742(-)	`GCTGGC/TTGCGC`	1	A/V	mis¹		5	NA EU EA WA	496
	rs33934967^1,2	C,F	188869716(-)	`ACCCAA/CCCAGA`	1	N/T	mis¹		10	NA EU CSAM EA WA	858
	rs34026617^1,2	F	188869267(-)	`TTCTCG/TGTRGC`	1	--	ng5¹		5	NA EU CSAM EA	380
--	rs34714141^1,2	F	188872824(-)	`AAGGTT/-AAGGA`	1	--	ng3¹		5	NA EU CSAM EA	380
	rs35435818^1,2	F	188872671(-)	`CTCCTG/CCTTTG`	1	--	ng3¹		5	NA EU CSAM EA	380
	rs4988512^1,2	H	188871153(+)	`ACACAT/AGCACA`	1	--	ng3¹		4	EU EA WA	420

About this table

HapMap Linkage Disequilibrium images for SST (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 182450

10/97 Novoseek disease relationships for SST gene (see all 97 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
acromegaly	92.94	341	16776333 (5), 11888834 (4), 17311857 (4), 18031313 (4) (see all 99)
neuroendocrine tumors	89.92	157	9408151 (4), 9002775 (3), 1359688 (3), 15819288 (3) (see all 99)
carcinoid	88.29	200	9002775 (3), 7574789 (3), 18049175 (3), 9622077 (3) (see all 99)
somatostatinoma	85.38	27	9189135 (2), 16105971 (2), 1686137 (1), 1969977 (1) (see all 22)
pituitary adenoma	84.44	125	12807513 (5), 15281350 (4), 10526255 (3), 16216913 (3) (see all 89)
vipoma	81.74	13	8197564 (2), 2177234 (1), 1685674 (1), 15646540 (1) (see all 12)
gastrinoma	81.18	20	9239629 (3), 14564638 (1), 2303679 (1), 1357826 (1) (see all 17)
serotonin syndrome	81.12	50	14699693 (3), 1377097 (2), 8625251 (2), 8977344 (2) (see all 44)
pituitary tumors	80.38	46	16452215 (3), 18243520 (2), 16263832 (2), 15857828 (2) (see all 37)
glucagonoma	80.28	12	8813473 (1), 1679271 (1), 12472080 (1), 14718149 (1) (see all 12)

About this table

Human Gene Mutation Database: SST
Genetic Association Database: SST
Human Genome Epidemiology Navigator: SST (19 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

Pasireotide (SOM230) Shows Promise for Treating Acromegaly, Cushing's Disease and Carcinoid Tumors: Presented at AACE

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/2793 PubMed articles for SST gene (see all 2793 ):

Sequence of the human somatostatin I gene. (PubMed id 6142531)^{2, 3, 4} Shen L.P. and Rutter W.J. (1984)
Human somatostatin I: sequence of the cDNA. (PubMed id 6126875)^{2, 3, 4} Shen L.-P.... Rutter W.J. (1982)
Genetic variation in the growth hormone synthesis pathway in relation to circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3, and breast cancer risk: results from the European prospective investigation into cancer and nutrition study. (PubMed id 16214911)^{3, 6} Canzian F....Kaaks R. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Somatostatin molecular variants in the vitreous fluid: a comparative study between diabetic patients with proliferative diabetic retinopathy and nondiabetic control subjects. (PubMed id 16043736)^{1, 3} Hernandez C....Simo R. (2005)
Lower somatostatin expression is an early event in diabetic retinopathy and is associated with retinal neurodegeneration. (PubMed id 17704349)^{1, 3} Carrasco E....Simo R. (2007)
Somatostatin is a selective chemoattractant for primitive (CD34(+)) hematopoietic progenitor cells. (PubMed id 11823046)^{1, 3} Oomen S.P....Touw I.P. (2002)
The Effect of Transforming Growth Factor {beta} on Human Neuroendocrine Tumor BON Cell Proliferation and Differentiation Is Mediated through Somatostatin Signaling. (PubMed id 18567806)^{1, 3} Leu F.P....Niu C. (2008)
Correlation between expression of gastrin, somatostatin and cell apoptosis regulation gene bcl-2/bax in large intestine carcinoma. (PubMed id 15655830)^{1, 3} Mao J.D....Xu G.Q. (2005)
Elevated circulating somatostatin levels in acromegaly. (PubMed id 12952361)^{1, 3} Arosio M....Peracchi M. (2003)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 6750	HGNC: 11329	AceView: SST	Ensembl:ENSG00000157005	euGenes: HUgn6750
ECgene: SST	H-InvDB: SST

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
Wikipedia	http://en.wikipedia.org/wiki/Somatostatin

Licensable Technologies for SST
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for SST:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for SST-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for SST		Antibodies for SST
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for SST		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (SST)
	Antibodies (SST)
	Chimera RNAi (SST)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (Somatostatin 14, Somatostatin 28, Somatostatin)
	Antibodies (Somatostatin 14, Somatostatin 28, Somatostatin)

Search OriGene for SST

Tocris compounds for SST

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for SST

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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SST Gene

protein-coding GIFtS: 60

Aliases &
Descriptions
for SST

Summaries
for SST

Genomic Location
for SST

Proteins
for SST

Protein Domains/
Families
for SST

Gene Function
for SST

Pathways & Interactions
for SST

Drugs & Compounds
for SST

Transcripts
for SST

Expression
for SST

Orthologs
for SST

Paralogs
for SST

SNPs/Variants
for SST

Disorders & Mutations
for SST

Medical News
for SST

Publications
for SST

Search for SST

Genome Databases showing SST

Other Databases showing SST

Specialized Databases showing SST

Licensable Technologies
for SST

Services
for SST

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

SST Gene

protein-coding GIFtS: 60

Aliases & Descriptionsfor SST

Summariesfor SST

Genomic Locationfor SST

Proteinsfor SST

Protein Domains/Familiesfor SST

Gene Functionfor SST

Pathways & Interactionsfor SST

Drugs & Compoundsfor SST

Transcriptsfor SST

Expression for SST

Orthologsfor SST

Paralogsfor SST

SNPs/Variantsfor SST

Disorders & Mutationsfor SST

Medical Newsfor SST

Publicationsfor SST

Search for SST

Genome Databases showing SST

Other Databases showing SST

Specialized Databases showing SST

Licensable Technologiesfor SST

Servicesfor SST

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for SST

Summaries
for SST

Genomic Location
for SST

Proteins
for SST

Protein Domains/
Families
for SST

Gene Function
for SST

Pathways & Interactions
for SST

Drugs & Compounds
for SST

Transcripts
for SST

Expression
for SST

Orthologs
for SST

Paralogs
for SST

SNPs/Variants
for SST

Disorders & Mutations
for SST

Medical News
for SST

Publications
for SST

Licensable Technologies
for SST

Services
for SST