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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SSR4 Gene

protein-coding   GIFtS: 61
GCID: GC0XP153058

Signal Sequence Receptor, Delta

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Signal Sequence Receptor, Delta1 2     SSR-delta2 3
TRAPD2 3 5     TRAP-delta2 3
Translocon-Associated Protein Delta1 2     Translocon-Associated Protein Subunit Delta2
Signal Sequence Receptor Subunit Delta2 3     

External Ids:    HGNC: 113261   Entrez Gene: 67482   Ensembl: ENSG000001808797   OMIM: 3000905   UniProtKB: P515713   
ORGUL members:         
NONCODE14:n410677      

Export aliases for SSR4 gene to outside databases

Previous GC identifers: GC0XP147197 GC0XP149515 GC0XP150644 GC0XP151526 GC0XP151527 GC0XP152579 GC0XP152712 GC0XP141717


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SSR4 Gene:
This gene encodes the delta subunit of the translocon-associated protein complex which is involved in
translocating proteins across the endoplasmic reticulum membrane. The encoded protein is located in the Xq28
region and is arranged in a compact head-to-head manner with the isocitrate dehydrogenase 3 (NAD+) gamma gene and
both genes are driven by a CpG-embedded bidirectional promoter. Alternate splicing results in multiple transcript
variants.(provided by RefSeq, Mar 2011)

GeneCards Summary for SSR4 Gene: 
SSR4 (signal sequence receptor, delta) is a protein-coding gene, and is affiliated with the lncRNA class. Diseases associated with SSR4 include terminal osseous dysplasia, and retinitis, and among its related super-pathways are Viral mRNA Translation and Generic Transcription Pathway. GO annotations related to this gene include calcium ion binding.

UniProtKB/Swiss-Prot: SSRD_HUMAN, P51571
Function: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby
regulate the retention of ER resident proteins

Gene Wiki entry for SSR4 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.2  NT_167198.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SSR4 gene promoter:
         c-Fos   TBP   NF-1/L   NF-1   AP-1   HEN1   Zic1   FOXO1a   ZIC2/Zic2   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSSR4 promoter sequence
   Search SABiosciences Chromatin IP Primers for SSR4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SSR4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq28   Ensembl cytogenetic band:  Xq28   HGNC cytogenetic band: Xq28

SSR4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SSR4 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP153058:  view genomic region     (about GC identifiers)

Start:
153,058,971 bp from pter      End:
153,063,967 bp from pter
Size:
4,997 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SSRD_HUMAN, P51571 (See protein sequence)
Recommended Name: Translocon-associated protein subunit delta precursor  
Size: 173 amino acids; 18999 Da
Subunit: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma
Subcellular location: Endoplasmic reticulum membrane; Single-pass type I membrane protein
Secondary accessions: A8K378 Q53XY1

Explore the universe of human proteins at neXtProt for SSR4: NX_P51571

Explore proteomics data for SSR4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P51571

  • SSR4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SSR4 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001191455.1  NP_001191456.1  NP_006271.1  

    ENSEMBL proteins: 
     ENSP00000317331   ENSP00000359104   ENSP00000359103   ENSP00000359102   ENSP00000399650  
    Reactome Protein details: P51571
    Human Recombinant Protein Products for SSR4: 
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    OriGene Protein Over-expression Lysate for SSR4
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    Novus Biologicals SSR4 Proteins
    Novus Biologicals SSR4 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    ProSpec Recombinant Protein for SSR4
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005783endoplasmic reticulum ----
    GO:0005784Sec61 translocon complex NAS7492314
    GO:0016021integral to membrane IEA--

    SSR4 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR008855 TRAP-delta

    Graphical View of Domain Structure for InterPro Entry P51571

    ProtoNet protein and cluster: P51571

    1 Blocks protein domain: IPB008855 Translocon-associated

    UniProtKB/Swiss-Prot: SSRD_HUMAN, P51571
    Similarity: Belongs to the TRAP-delta family


    SSR4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SSRD_HUMAN, P51571
    Function: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby
    regulate the retention of ER resident proteins

         Genatlas biochemistry entry for SSR4:
    signal sequence receptor delta,with an alternative polyadenylation site,expressed in many tissues

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding NAS--
         
    SSR4 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SSR4:
     Decreased viability of wild-ty 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SSR4 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SSR4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SSR4 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SSR4 

    miRNA
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                         Customized lentivirus expression plasmids for stable overexpression of SSR4 

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SSR4


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SSR4 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Viral mRNA Translation
    Translation0.78
    SRP-dependent cotranslational protein targeting to membrane0.77
    2Generic Transcription Pathway
    Gene Expression0.47
    3Asparagine N-linked glycosylation
    Metabolism of proteins0.35
    4Protein processing in endoplasmic reticulum
    Protein processing in endoplasmic reticulum

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    4        Reactome Pathways for SSR4
        Translation
    SRP-dependent cotranslational protein targeting to membrane
    Metabolism of proteins
    Gene Expression


    1         Kegg Pathway  (Kegg details for SSR4):
        Protein processing in endoplasmic reticulum


    SSR4 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SSR4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/186 Interacting proteins for SSR4 (P515711, 2, 3 ENSP000003173314) via UniProtKB, MINT, STRING, and/or I2D (see all 186)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    C20orf24Q9BUV81, 3, ENSP000003412134EBI-1054539,EBI-1050079 I2D: score=2 STRING: ENSP00000341213
    RIOK3O147301, 3, ENSP000003418744EBI-1054539,EBI-1047061 I2D: score=2 STRING: ENSP00000341874
    CBWD1Q9BRT81, 3, ENSP000003489154EBI-1054539,EBI-1054417 I2D: score=1 STRING: ENSP00000348915
    SSR1P433072, 3, ENSP000002447634MINT-4546703 I2D: score=1 STRING: ENSP00000244763
    MAP3K1Q132332, 3MINT-48297 I2D: score=2 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006412translation TAS--
    GO:0006614SRP-dependent cotranslational protein targeting to membrane TAS--
    GO:0006886intracellular protein transport NAS--
    GO:0010467gene expression TAS--
    GO:0044267cellular protein metabolic process TAS--

    SSR4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SSR4 (SSRD)

    1 HMDB Compound for SSR4    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    Search CenterWatch for drugs/clinical trials and news about SSR4 / SSRD

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SSR4 gene (3 alternative transcripts): 
    NM_001204526.1  NM_001204527.1  NM_006280.2  

    Unigene Cluster for SSR4:

    Signal sequence receptor, delta
    Hs.409223  [show with all ESTs]
    Unigene Representative Sequence: BC032351
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000320857(uc022chw.1 uc004fiv.3) ENST00000491833 ENST00000370087
    ENST00000482902(uc022chx.1) ENST00000370086(uc004fiw.3) ENST00000460616
    ENST00000370085 ENST00000471724 ENST00000471880 ENST00000489777 ENST00000486204
    ENST00000485612 ENST00000447375
    miRNA
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SSR4
    Sirion Biotech Customized lentivirus for stable overexpression of SSR4 
                         Customized lentivirus expression plasmids for stable overexpression of SSR4 
    Primer
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    OriGene qPCR primer pairs and template standards for SSR4
    OriGene qSTAR qPCR primer pairs in human, mouse for SSR4
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SSR4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SSR4

    Additional mRNA sequence: 

    AK290493.1 BC003371.1 BC015362.2 BC032351.1 BT007192.1 NR_037927.1 X90583.1 Z69043.1 

    20 DOTS entries:

    DT.95164179  DT.100854831  DT.100854838  DT.121309368  DT.100854830  DT.121309436  DT.319744  DT.95142095 
    DT.95164167  DT.97864675  DT.100854840  DT.121309359  DT.100854819  DT.91829470  DT.100854823  DT.100854827 
    DT.100854842  DT.102836114  DT.121309469  DT.92447436 

    24/636 AceView cDNA sequences (see all 636):

    Z69043 BM997363 BU781668 BM761847 CB108378 BM766441 AI087026 BQ128169 
    AI192747 AI146648 BM996690 AA437238 BQ672202 AI075992 AK094395 BX280492 
    CB107998 BQ005874 BU070939 BQ052161 AI636819 CD513596 BM988633 AA847250 

    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for SSR4 (see all 12)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c · 5d · 5e ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10a · 10b
    SP1:                                      -                 -     -     -     -     -                                   -               
    SP2:                                      -     -     -     -     -     -     -     -                                   -               
    SP3:                                            -     -     -     -     -     -     -                                   -               
    SP4:                                                                                                                    -               
    SP5:                                      -     -     -     -     -     -     -     -                                                   


    ECgene alternative splicing isoforms for SSR4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SSR4 expression in normal human tissues (normalized intensities)      SSR4 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTCTCTATG
    SSR4 Expression
    About this image


    SSR4 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Tooth (Integumentary System)    fully expand to see all 4 entries
             visceral organ/oral region/upper jaw   
     
     Bone (Muscoskeletal System)    fully expand to see all 3 entries
             Endochondral Facial Bones
             skeleton/cranium/chondrocranium   
     
     Cartilage (Muscoskeletal System)    fully expand to see all 3 entries
             Meckel's Cartilage
             skeleton/cranium/chondrocranium   
     
     Neural Crest (Gastrulation Derivatives)    fully expand to see all 2 entries
             skeleton/cranium/chondrocranium   

     -- (Gastrointestinal Tract)
             visceral organ/oral region/gland   

    See SSR4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SSR4

    SOURCE GeneReport for Unigene cluster: Hs.409223
        SABiosciences Custom PCR Arrays for SSR4
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SSR4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SSR4 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ssr41 , 5 signal sequence receptor, delta1, 5 86.63(n)1
    95.35(a)1
      X (37.41 cM)5
    208321  NM_009279.31  NP_033305.11 
     737870625 
    lizard
    (Anolis carolinensis)
    Reptilia SSR46
    signal sequence receptor, delta
    75(a)
    1 ↔ 1
    2(87858559-87868376)
    African clawed frog
    (Xenopus laevis)
    Amphibia X90584.12   -- 73.73(n)    X90584.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufe06a082 Transcribed sequence with moderate similarity to protein more 73.57(n)    CD778039.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Tapdelta1 Translocon-associated protein delta 48.64(n)
    35.22(a)
      45680  NM_136835.3  NP_610679.1 
    worm
    (Caenorhabditis elegans)
    Secernentea trap-46
    Protein TRAP-4
    33(a)
    1 ↔ 1
    III(11920716-11921618)


    ENSEMBL Gene Tree for SSR4 (if available)
    TreeFam Gene Tree for SSR4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SSR4 gene

    SSR4 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SSR4
    PGOHUM00000239095


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/67 SNPs in SSR4 are shown (see all 67)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0641614
    ----see VAR_0641612 G R mis40--------
    rs2011937401,2
    --153061989(+) CTGACA/GTGCAA 7 T syn10--------
    rs1877819011,2
    --153062448(+) CTCCTC/TTCAGT 4 -- int10--------
    rs1488704731,2
    --153062463(+) TAAGTA/GGCTGG 4 -- int10--------
    rs1924667681,2
    --153062588(+) GGGCAC/TCCCTG 4 -- int10--------
    rs120093561,2
    C,F,H--153062668(+) TCAACA/GGGGTT 4 -- int110Minor allele frequency- G:0.05NS EA NA CSA 1099
    rs1131789751,2
    C,F--153062699(+) CGGCCG/ATGGGG 4 -- int11Minor allele frequency- A:0.00CSA 1
    rs59451651,2
    C,F,H--153062772(+) GTTACC/TTGGTA 4 -- int113Minor allele frequency- T:0.01NS EA WA NA CSA 437
    rs117958881,2
    C,F,H--153062801(+) GCAGCC/TCCCAA 4 -- int15Minor allele frequency- T:0.01NS EA NA 420
    rs800069701,2
    C--153062829(+) ACCTGA/CAGGCC 4 -- int10--------

    HapMap Linkage Disequilibrium report for SSR4 (153058971 - 153063967 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for SSR4:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv33199CNV Gain+Loss17666407

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 300090    OMIM disorders: --

    3 diseases for SSR4:    About MalaCards
    terminal osseous dysplasia    retinitis    melanoma


    SSR4 for disorders           About GeneDecksing


    Export disorders for SSR4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SSR4 gene, integrated from 9 sources (see all 43):
    (articles sorted by number of sources associating them with SSR4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genomic organization of two novel genes on human Xq28: compact head to head arrangement of IDH gamma and TRAP delta is conserved in rat and mouse. (PubMed id 9286695)1, 2, 3, 9 Brenner V.... Platzer M. (1997)
    2. Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry. (PubMed id 18781797)1, 2 Meierhofer D.... Kaiser P. (2008)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Translocon-associated protein TRAP delta and a novel TRAP-like protein are coordinately expressed with pro-opiomelanocortin in Xenopus intermediate pituitary. (PubMed id 7492314)1, 2 Holthuis J.C.M.... Martens G.J.M. (1995)
    6. Cloning and molecular characterization of a human ortholog of Monodelphis TRAPD in ultraviolet B-induced melanoma. (PubMed id 15057039)1, 9 Wang Z. and VandeBerg J.L. (2004)
    7. NEDL1, a novel ubiquitin-protein isopeptide ligase for dishevelled-1, targets mutant superoxide dismutase-1. (PubMed id 14684739)1, 9 Miyazaki K....Nakagawara A. (2004)
    8. Drafting the CLN3 protein interactome in SH-SY5Y human neuroblastoma cells: a label-free quantitative proteomics approach. (PubMed id 23464991)1 Scifo E....Lalowski M. (2013)
    9. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    10. Proteomic analysis of the NOS2 interactome in human ai rway epithelial cells. (PubMed id 23438482)1 Foster M.W....Marshall H.E. (2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6748 HGNC: 11326 AceView: SSR4 Ensembl:ENSG00000180879 euGenes: HUgn6748
    ECgene: SSR4 Kegg: 6748 H-InvDB: SSR4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SSR4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SSR4 gene:
    Search GeneIP for patents involving SSR4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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