Aliases for SSR4 Gene
External Ids for SSR4 Gene
This gene encodes the delta subunit of the translocon-associated protein complex which is involved in translocating proteins across the endoplasmic reticulum membrane. The encoded protein is located in the Xq28 region and is arranged in a compact head-to-head manner with the isocitrate dehydrogenase 3 (NAD+) gamma gene and both genes are driven by a CpG-embedded bidirectional promoter. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2011]
GeneCards Summary for SSR4 Gene
SSR4 (Signal Sequence Receptor, Delta) is a Protein Coding gene. Diseases associated with SSR4 include ssr4-cdg and congenital disorder of glycosylation, type iy. Among its related pathways are Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein and Gene Expression. GO annotations related to this gene include calcium ion binding.
UniProtKB/Swiss-Prot for SSR4 Gene
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins