Aliases for SSR4 Gene
External Ids for SSR4 Gene
Previous GeneCards Identifiers for SSR4 Gene
This gene encodes the delta subunit of the translocon-associated protein complex which is involved in translocating proteins across the endoplasmic reticulum membrane. The encoded protein is located in the Xq28 region and is arranged in a compact head-to-head manner with the isocitrate dehydrogenase 3 (NAD+) gamma gene and both genes are driven by a CpG-embedded bidirectional promoter. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2011]
GeneCards Summary for SSR4 Gene
SSR4 (Signal Sequence Receptor Subunit 4) is a Protein Coding gene. Diseases associated with SSR4 include Congenital Disorder Of Glycosylation, Type Iy and Ssr4-Cdg. Among its related pathways are Protein processing in endoplasmic reticulum and Gene Expression.
UniProtKB/Swiss-Prot for SSR4 Gene
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.