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Aliases for SSNA1 Gene

Aliases for SSNA1 Gene

  • Sjogren Syndrome Nuclear Autoantigen 1 2 3
  • NA14 3 4 6
  • Sjogrens Syndrome Nuclear Autoantigen 1 2 3
  • Nuclear Autoantigen Of 14 KDa 3 4
  • Sjoegren Syndrome Nuclear Autoantigen 1 3
  • NA-14 3
  • N14 3

External Ids for SSNA1 Gene

Summaries for SSNA1 Gene

GeneCards Summary for SSNA1 Gene

SSNA1 (Sjogren Syndrome Nuclear Autoantigen 1) is a Protein Coding gene. Diseases associated with SSNA1 include paralytic squint and sjogrens syndrome. Among its related pathways are Cell Cycle, Mitotic and Cell Cycle, Mitotic. GO annotations related to this gene include identical protein binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SSNA1 Gene

Genomics for SSNA1 Gene

Genomic Location for SSNA1 Gene

137,188,602 bp from pter
137,190,370 bp from pter
1,769 bases
Plus strand

Genomic View for SSNA1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SSNA1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SSNA1 Gene

Regulatory Elements for SSNA1 Gene

Transcription factor binding sites by QIAGEN in the SSNA1 gene promoter:

Proteins for SSNA1 Gene

  • Protein details for SSNA1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Sjoegren syndrome nuclear autoantigen 1
    Protein Accession:
    Secondary Accessions:
    • Q5VSG0
    • Q6FG70
    • Q9BVW8

    Protein attributes for SSNA1 Gene

    119 amino acids
    Molecular mass:
    13596 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SSNA1 Gene

Proteomics data for SSNA1 Gene at MOPED

Post-translational modifications for SSNA1 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys97

Other Protein References for SSNA1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for SSNA1 Gene

Domains for SSNA1 Gene

Protein Domains for SSNA1 Gene



  • Belongs to the SSNA1 family.:
    • O43805
genes like me logo Genes that share domains with SSNA1: view

No data available for Gene Families for SSNA1 Gene

Function for SSNA1 Gene

Gene Ontology (GO) - Molecular Function for SSNA1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0042802 identical protein binding IEA --
genes like me logo Genes that share ontologies with SSNA1: view

Phenotypes for SSNA1 Gene

GenomeRNAi human phenotypes for SSNA1:
genes like me logo Genes that share phenotypes with SSNA1: view

miRNA for SSNA1 Gene

miRTarBase miRNAs that target SSNA1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for SSNA1 Gene

Localization for SSNA1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SSNA1 Gene

Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

Subcellular locations from

Jensen Localization Image for SSNA1 Gene COMPARTMENTS Subcellular localization image for SSNA1 gene
Compartment Confidence
cytoskeleton 5
nucleus 5
cytosol 4
extracellular 1

Gene Ontology (GO) - Cellular Components for SSNA1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005813 centrosome IDA 21399614
GO:0005829 cytosol TAS --
GO:0036064 ciliary basal body IEA --
genes like me logo Genes that share ontologies with SSNA1: view

Pathways for SSNA1 Gene

genes like me logo Genes that share pathways with SSNA1: view

Gene Ontology (GO) - Biological Process for SSNA1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000086 G2/M transition of mitotic cell cycle TAS --
GO:0000278 mitotic cell cycle TAS --
GO:0006996 organelle organization TAS --
GO:0042073 intraciliary transport IEA --
GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway IEA --
genes like me logo Genes that share ontologies with SSNA1: view

Transcripts for SSNA1 Gene

mRNA/cDNA for SSNA1 Gene

Unigene Clusters for SSNA1 Gene

Sjogren syndrome nuclear autoantigen 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SSNA1 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b · 3c · 3d
SP2: -
SP4: -

Relevant External Links for SSNA1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SSNA1 Gene

mRNA expression in normal human tissues for SSNA1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for SSNA1 Gene

SOURCE GeneReport for Unigene cluster for SSNA1 Gene Hs.530314

mRNA Expression by UniProt/SwissProt for SSNA1 Gene

Tissue specificity: Widely expressed.
genes like me logo Genes that share expressions with SSNA1: view

Orthologs for SSNA1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SSNA1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SSNA1 36
  • 98.6 (n)
  • 98.32 (a)
SSNA1 37
  • 97 (a)
(Bos Taurus)
Mammalia SSNA1 36
  • 90.2 (n)
  • 94.96 (a)
SSNA1 37
  • 94 (a)
(Canis familiaris)
Mammalia SSNA1 36
  • 90.2 (n)
  • 95.8 (a)
SSNA1 37
  • 90 (a)
(Mus musculus)
Mammalia Ssna1 36
  • 90.2 (n)
  • 97.48 (a)
Ssna1 16
Ssna1 37
  • 97 (a)
(Monodelphis domestica)
Mammalia SSNA1 37
  • 93 (a)
(Ornithorhynchus anatinus)
Mammalia SSNA1 37
  • 76 (a)
(Gallus gallus)
Aves LOC771190 36
  • 61.95 (n)
  • 51.33 (a)
(Anolis carolinensis)
Reptilia SSNA1 37
  • 55 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.8082 36
tropical clawed frog
(Silurana tropicalis)
Amphibia ssna1 36
  • 77.57 (n)
  • 80.37 (a)
Str.5896 36
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.1544 36
(Danio rerio)
Actinopterygii ssna1 36
  • 73.09 (n)
  • 78.9 (a)
ssna1 37
  • 74 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.2900 36
Species with no ortholog for SSNA1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SSNA1 Gene

Gene Tree for SSNA1 (if available)
Gene Tree for SSNA1 (if available)

Paralogs for SSNA1 Gene

Selected SIMAP similar genes for SSNA1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SSNA1: view

No data available for Paralogs for SSNA1 Gene

Variants for SSNA1 Gene

Sequence variations from dbSNP and Humsavar for SSNA1 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs60073116 -- 137,190,608(+) GCTCA(A/C)CCTCC downstream-variant-500B
rs67506437 -- 137,190,758(+) GGGGA(C/G)TTCAC downstream-variant-500B
rs72763289 -- 137,190,727(+) TCAGA(C/T)TCAGG downstream-variant-500B
rs72763290 -- 137,190,730(+) GATTC(A/G)GGTCC downstream-variant-500B
rs73563672 -- 137,190,817(+) TGACA(A/C)CACTG downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for SSNA1 Gene

Variant ID Type Subtype PubMed ID
nsv894387 CNV Gain 21882294
esv2422220 CNV Deletion 17116639
dgv8412n71 CNV Loss 21882294
dgv8416n71 CNV Loss 21882294
nsv524322 CNV Loss 19592680
nsv894469 CNV Loss 21882294
dgv8423n71 CNV Loss 21882294
nsv894502 CNV Loss 21882294
nsv894506 CNV Gain 21882294
dgv8428n71 CNV Loss 21882294
nsv894521 CNV Loss 21882294
dgv8437n71 CNV Gain 21882294
dgv8439n71 CNV Loss 21882294
dgv8441n71 CNV Loss 21882294
dgv8442n71 CNV Loss 21882294
dgv8445n71 CNV Loss 21882294
dgv8446n71 CNV Loss 21882294
dgv8447n71 CNV Loss 21882294
dgv8450n71 CNV Loss 21882294
nsv894603 CNV Gain+Loss 21882294
dgv8451n71 CNV Loss 21882294
dgv8452n71 CNV Gain+Loss 21882294
dgv8453n71 CNV Gain 21882294
dgv8454n71 CNV Gain 21882294
dgv8455n71 CNV Gain+Loss 21882294

Relevant External Links for SSNA1 Gene

HapMap Linkage Disequilibrium report

Disorders for SSNA1 Gene

(1) University of Copenhagen DISEASES for SSNA1 Gene

genes like me logo Genes that share disorders with SSNA1: view

No data available for UniProtKB/Swiss-Prot for SSNA1 Gene

Publications for SSNA1 Gene

  1. NA14 is a novel nuclear autoantigen with a coiled-coil domain. (PMID: 9430706) Ramos-Morales F. … Rios R.M. (J. Biol. Chem. 1998) 2 3 4
  2. Proteomic characterization of the human centrosome by protein correlation profiling. (PMID: 14654843) Andersen J.S. … Mann M. (Nature 2003) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation. (PMID: 16462731) Petretti C. … Giet R. (EMBO Rep. 2006) 3
  5. Defining the human deubiquitinating enzyme interaction landscape. (PMID: 19615732) Sowa M.E. … Harper J.W. (Cell 2009) 3

Products for SSNA1 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate SSNA1
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for SSNA1
    • Block miRNA regulation of SSNA1 using miScript Target Protectors

    Sources for SSNA1 Gene

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