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Aliases for SSMEM1 Gene

Aliases for SSMEM1 Gene

  • Serine-Rich Single-Pass Membrane Protein 1 2 3
  • C7orf45 3 4
  • Chromosome 7 Open Reading Frame 45 2

External Ids for SSMEM1 Gene

Previous HGNC Symbols for SSMEM1 Gene

  • C7orf45

Previous GeneCards Identifiers for SSMEM1 Gene

  • GC07P129848

Summaries for SSMEM1 Gene

GeneCards Summary for SSMEM1 Gene

SSMEM1 (Serine-Rich Single-Pass Membrane Protein 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SSMEM1 Gene

Genomics for SSMEM1 Gene

Genomic Location for SSMEM1 Gene

130,205,525 bp from pter
130,216,844 bp from pter
11,320 bases
Plus strand

Genomic View for SSMEM1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SSMEM1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SSMEM1 Gene

No data available for Regulatory Elements for SSMEM1 Gene

Proteins for SSMEM1 Gene

  • Protein details for SSMEM1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Serine-rich single-pass membrane protein 1
    Protein Accession:
    Secondary Accessions:

    Protein attributes for SSMEM1 Gene

    244 amino acids
    Molecular mass:
    28167 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SSMEM1 Gene

Proteomics data for SSMEM1 Gene at MOPED

Post-translational modifications for SSMEM1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SSMEM1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SSMEM1 Gene

Domains for SSMEM1 Gene

Protein Domains for SSMEM1 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SSMEM1: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SSMEM1 Gene

Function for SSMEM1 Gene

genes like me logo Genes that share phenotypes with SSMEM1: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SSMEM1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SSMEM1 Gene

Localization for SSMEM1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SSMEM1 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SSMEM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SSMEM1: view

No data available for Subcellular locations from COMPARTMENTS for SSMEM1 Gene

Pathways for SSMEM1 Gene

SuperPathways for SSMEM1 Gene

No Data Available

Interacting Proteins for SSMEM1 Gene

Gene Ontology (GO) - Biological Process for SSMEM1 Gene


No data available for Pathways by source for SSMEM1 Gene

Transcripts for SSMEM1 Gene

mRNA/cDNA for SSMEM1 Gene

(4) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SSMEM1 Gene

Serine-rich single-pass membrane protein 1:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SSMEM1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SSMEM1 Gene

No ASD Table

Relevant External Links for SSMEM1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SSMEM1 Gene

mRNA expression in normal human tissues for SSMEM1 Gene

mRNA differential expression in normal tissues according to GTEx for SSMEM1 Gene

This gene is overexpressed in Testis (50.4).

Protein differential expression in normal tissues for SSMEM1 Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for SSMEM1 Gene

SOURCE GeneReport for Unigene cluster for SSMEM1 Gene Hs.351816

genes like me logo Genes that share expressions with SSMEM1: view

Expression partners for SSMEM1 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for SSMEM1 Gene

Orthologs for SSMEM1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for SSMEM1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SSMEM1 35
  • 84.79 (n)
  • 73.03 (a)
MGC127766 36
  • 73 (a)
(Canis familiaris)
Mammalia SSMEM1 35
  • 85.79 (n)
  • 77.46 (a)
  • 77 (a)
(Mus musculus)
Mammalia Ssmem1 35
  • 75.55 (n)
  • 67.62 (a)
1700025E21Rik 16
Ssmem1 36
  • 68 (a)
(Pan troglodytes)
Mammalia SSMEM1 35
  • 98.06 (n)
  • 95.44 (a)
  • 96 (a)
(Rattus norvegicus)
Mammalia Ssmem1 35
  • 73.44 (n)
  • 63.02 (a)
(Monodelphis domestica)
Mammalia SSMEM1 36
  • 59 (a)
(Ornithorhynchus anatinus)
Mammalia SSMEM1 36
  • 47 (a)
Species with no ortholog for SSMEM1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SSMEM1 Gene

Gene Tree for SSMEM1 (if available)
Gene Tree for SSMEM1 (if available)

Paralogs for SSMEM1 Gene

(1) SIMAP similar genes for SSMEM1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SSMEM1: view

No data available for Paralogs for SSMEM1 Gene

Variants for SSMEM1 Gene

Sequence variations from dbSNP and Humsavar for SSMEM1 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs2087242 -- 130,214,913(+) atttt(C/T)gtggt intron-variant
rs2633380 -- 130,208,667(+) AGATA(C/T)GAAAG intron-variant
rs2633381 -- 130,210,586(+) CAAAC(A/G)CCTTA intron-variant
rs2633382 -- 130,210,674(+) AGCCA(C/G)GGCCC intron-variant
rs2633383 -- 130,212,653(+) ctggg(A/G)ggcgg intron-variant

Relevant External Links for SSMEM1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SSMEM1 Gene

Disorders for SSMEM1 Gene

No disorders were found for SSMEM1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for SSMEM1 Gene

Publications for SSMEM1 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3

Products for SSMEM1 Gene

Sources for SSMEM1 Gene

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