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SSFA2 Gene

protein-coding   GIFtS: 55
GCID: GC02P182720

Sperm Specific Antigen 2

  Search for SSFA2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Sperm Specific Antigen 21 2     CS-12 3
Cleavage Signal-1 Protein1 2 3     KRAP2 3
CS12 3 5     SPAG132
KRAS-Induced Actin-Interacting Protein1 2     Sperm-Specific Antigen 22
Sperm Associated Antigen 131 2     KIAA19273
Ki-Ras-Induced Actin-Interacting Protein2 3     

External Ids:    HGNC: 113191   Entrez Gene: 67442   Ensembl: ENSG000001384347   OMIM: 1189905   UniProtKB: P282903   

Export aliases for SSFA2 gene to outside databases

Previous GC identifers: GC02P180990 GC02P181439 GC02P182959 GC02P182582 GC02P182464 GC02P174612


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SSFA2 Gene:
SSFA2 (sperm specific antigen 2) is a protein-coding gene. GO annotations related to this gene include actin binding. An important paralog of this gene is CCDC129.

Gene Wiki entry for SSFA2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NT_005403.18  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SSFA2 gene promoter:
         TBP   Nkx2-5   C/EBPalpha   POU2F1   Nkx6-1   E2F   E2F-1   TFIID   ARP-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSSFA2 promoter sequence
   Search Chromatin IP Primers for SSFA2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SSFA2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q31.3   Ensembl cytogenetic band:  2q31.3   HGNC cytogenetic band: 2q32.1

SSFA2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SSFA2 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P182720:  view genomic region     (about GC identifiers)

Start:
182,756,472 bp from pter      End:
182,795,465 bp from pter
Size:
38,994 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SSFA2_HUMAN, P28290 (See protein sequence)
Recommended Name: Sperm-specific antigen 2  
Size: 1259 amino acids; 138386 Da
Sequence caution: Sequence=AAB00773.1; Type=Erroneous initiation; Sequence=AAH12947.1; Type=Erroneous initiation;
Sequence=BAB67820.2; Type=Erroneous initiation; Sequence=BAC05308.1; Type=Erroneous initiation;
Secondary accessions: A8K6T0 Q68DA6 Q7Z7L2 Q8N1L3 Q8N263 Q8N7H2 Q8NEN5 Q96E36 Q96PW1
Alternative splicing: 3 isoforms:  P28290-1   P28290-2   P28290-3   

Explore the universe of human proteins at neXtProt for SSFA2: NX_P28290

Explore proteomics data for SSFA2 at MOPED

Post-translational modifications: 

  • A 33 kDa peptide corresponding to the C-terminus of this protein is found in the testis and seems to be cleaved
    into 2 peptides of 14 kDa and 18 kDa found on the surface of mature sperm cells. This sperm surface antigen may
    be involved in some step of early cleavage of the fertilized oocyte1
  • Ubiquitination2 at Lys212
  • Modification sites at PhosphoSitePlus

  • See SSFA2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (5 alternative transcripts): 
    NP_001123917.1  NP_001274432.1  NP_001274433.1  NP_001274434.1  NP_006742.2  

    ENSEMBL proteins: 
     ENSP00000388731   ENSP00000314669   ENSP00000387319   ENSP00000392049   ENSP00000403754  
     ENSP00000415625   ENSP00000386916   ENSP00000387420   ENSP00000409867  

    SSFA2 Human Recombinant Protein Products:

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    Cloud-Clone Corp. CLIAs for SSFA2
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR026648 SSFA2

    Graphical View of Domain Structure for InterPro Entry P28290

    ProtoNet protein and cluster: P28290


    Find genes that share domains with SSFA2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SSFA2_HUMAN, P28290
    Induction: Up-regulated by activated KRAS

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003779actin binding IEA--
         
    Find genes that share ontologies with SSFA2           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for SSFA2:
     Increased G1 DNA content 

         7 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ssfa2):
     adipose tissue  behavior/neurological  digestive/alimentary  growth/size/body  homeostasis/metabolism 
     integument  liver/biliary system 

    Find genes that share phenotypes with SSFA2           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Ssfa2tm1Sawa for SSFA2

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SSFA2
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SSFA2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SSFA2

    miRNA
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    miRTarBase miRNAs that target SSFA2:
    hsa-mir-32-5p (MIRT028371), hsa-mir-21-5p (MIRT030920), hsa-mir-124-3p (MIRT002633), hsa-mir-101-3p (MIRT027355), hsa-mir-128-3p (MIRT021999)

    Block miRNA regulation of human, mouse, rat SSFA2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SSFA2 (see all 17):
    hsa-miR-498 hsa-miR-137 hsa-miR-875-5p hsa-miR-25 hsa-miR-1297 hsa-miR-124 hsa-miR-1244 hsa-miR-506
    SwitchGear 3'UTR luciferase reporter plasmidSSFA2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SSFA2

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SSFA2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SSFA2_HUMAN, P28290: Cytoplasm. Note=Located near the plasma membrane. Associated with actin filaments. May also
    exist as a membrane-bound form with extracellular regions
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane4
    nucleus3
    cytoskeleton1
    cytosol1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005886plasma membrane IDA--

    Find genes that share ontologies with SSFA2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SSFA2
    Interactions:

        Search GeneGlobe Interaction Network for SSFA2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    Selected Interacting proteins for SSFA2 (P282902, 3 ENSP000003887314) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LUC7L2Q9Y3832, 3MINT-65246 I2D: score=5 
    C7orf55-LUC7L2Q9Y3832, 3, ENSP000003470054MINT-65246 I2D: score=5 STRING: ENSP00000347005
    YWHAEP622583, ENSP000002643354I2D: score=3 STRING: ENSP00000264335
    YWHAGP619813, ENSP000003063304I2D: score=3 STRING: ENSP00000306330
    YWHAZP631043, ENSP000003095034I2D: score=2 STRING: ENSP00000309503
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SSFA2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SSFA2 gene (5 alternative transcripts): 
    NM_001130445.2  NM_001287503.1  NM_001287504.1  NM_001287505.1  NM_006751.6  

    Unigene Cluster for SSFA2:

    Sperm specific antigen 2
    Hs.196983  [show with all ESTs]
    Unigene Representative Sequence: NM_001130445
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000480753(uc010zfn.1) ENST00000431877(uc002uoi.3 uc002uoh.3 uc002uoj.3 uc010zfo.2)
    ENST00000320370 ENST00000409001 ENST00000454579 ENST00000440623(uc002uok.3)
    ENST00000495248 ENST00000470129 ENST00000416081(uc002uol.3) ENST00000470654
    ENST00000491720 ENST00000409136(uc002uom.3) ENST00000491866 ENST00000467172
    ENST00000451836 ENST00000428267
    miRNA
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    Block miRNA regulation of human, mouse, rat SSFA2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SSFA2 (see all 17):
    hsa-miR-498 hsa-miR-137 hsa-miR-875-5p hsa-miR-25 hsa-miR-1297 hsa-miR-124 hsa-miR-1244 hsa-miR-506
    SwitchGear 3'UTR luciferase reporter plasmidSSFA2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SSFA2
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    OriGene ORF clones in mouse, rat for SSFA2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): SSFA2 (NM_006751)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SSFA2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SSFA2
    Primer
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    OriGene qPCR primer pairs and template standards for SSFA2
    OriGene qSTAR qPCR primer pairs in human, mouse for SSFA2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SSFA2
      QuantiTect SYBR Green Assays in human, mouse, rat SSFA2
      QuantiFast Probe-based Assays in human, mouse, rat SSFA2

    Additional mRNA sequence: 

    AB067514.2 AB116937.1 AK091197.1 AK093143.1 AK097375.1 AK098455.1 AK127890.1 AK291745.1 
    AK298186.1 AK298949.1 AK304238.1 AL833431.1 BC012947.1 BC028706.2 BC037334.2 BC052581.1 
    BC064499.1 BX647257.1 BX647967.1 CR749488.1 M61199.1 

    16 DOTS entries:

    DT.446286  DT.99988668  DT.100679951  DT.91656787  DT.100786858  DT.100786870  DT.87014772  DT.100786873 
    DT.100749811  DT.91796715  DT.95148495  DT.95148497  DT.120982399  DT.95148492  DT.95148496  DT.95251781 

    Selected AceView cDNA sequences (see all 344):

    BU163176 CN484389 BU742413 BC028706 BQ688420 BU145841 BQ689994 CB105160 
    BM474252 AX747951 BM818291 AW452352 BU179686 AL600287 BQ687732 BU742607 
    BQ685588 BQ684889 AV659284 BQ892756 BX647967 NM_006751 BQ017276 AK091197 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SSFA2 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b · 12c · 12d ^ 13 ^ 14 ^ 15 ^ 16a · 16b · 16c ^ 17 ^ 18 ^
    SP1:                                                                                                        -                                                   
    SP2:                                                                                                                                                            
    SP3:                                                                                                        -                                               -   
    SP4:                                                                                                        -                       -     -     -               
    SP5:                                                                                                        -                                   -               

    ExUns: 19a · 19b · 19c
    SP1:                  
    SP2:                  
    SP3:                  
    SP4:                  
    SP5:                  


    ECgene alternative splicing isoforms for SSFA2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SSFA2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATCCTATTA
    SSFA2 Expression
    About this image


    SSFA2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 11) fully expand
     
     Heart (Cardiovascular System)
             Cardiac Fibroblasts Myocardium
     
     Fibroblasts
             Cardiac Fibroblasts Myocardium
     
     Colon (Gastrointestinal Tract)
     
     Kidney (Urinary System)
     
     Thyroid (Endocrine System)
    SSFA2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SSFA2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.196983

    UniProtKB/Swiss-Prot: SSFA2_HUMAN, P28290
    Tissue specificity: Strongly expressed in pancreas and testis. Present in colon cancer cells (at protein level)

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    QuantiFast Probe-based Assays in human, mouse, rat SSFA2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SSFA2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for SSFA2 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ssfa21 , 5 sperm specific antigen 21, 5 81.43(n)1
    82.43(a)1
      2 (47.58 cM)5
    705991  NM_080558.41  NP_542125.31 
     796353525 
    chicken
    (Gallus gallus)
    Aves SSFA21 sperm specific antigen 2 68.36(n)
    64.36(a)
      424118  XM_004942690.1  XP_004942747.1 
    lizard
    (Anolis carolinensis)
    Reptilia SSFA26
    sperm specific antigen 2
    57(a)
    1 ↔ 1
    GL343221.1(2539044-2614208)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.184822 Xenopus laevis transcribed sequence 84.69(n)    BI347898.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ssfa21 sperm specific antigen 2 50.13(n)
    40(a)
      553255  XM_001918944.4  XP_001918979.4 


    ENSEMBL Gene Tree for SSFA2 (if available)
    TreeFam Gene Tree for SSFA2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SSFA2 gene
    CCDC1292  TESPA12  

    Find genes that share paralogs with SSFA2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SSFA2 (see all 853)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2015435931,2
    Cuntested1182780760(+) TAAATC/TGACCA 4 S L mis10--------
    rs1427792581,2
    --182754489(+) ATAATA/CAATTT 2 -- us2k10--------
    rs1923877521,2
    --182754497(+) TTTAGA/GTGTCT 2 -- us2k10--------
    rs744762391,2
    C,F--182754649(+) AAACAT/CACCTT 2 -- us2k11Minor allele frequency- C:0.07EA 120
    rs1848861591,2
    --182754946(+) AACTTC/TGAAGG 2 -- us2k10--------
    rs1896450501,2
    --182754950(+) TTGAAA/GGCAGC 2 -- us2k10--------
    rs1469824021,2
    --182755094(+) TCCTAC/TTACAG 2 -- us2k10--------
    rs1808208581,2
    --182755136(+) TCAAAG/TAAAAG 2 -- us2k10--------
    rs1382297621,2
    --182755213(+) TGGCAG/TTACAT 2 -- us2k10--------
    rs1495317551,2
    --182755234(+) CAGGAA/GAATAT 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for SSFA2 (182756472 - 182795465 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for SSFA2:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv834478CNV Gain17160897
    nsv834479CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SSFA2
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 118990    OMIM disorders: --


    Find genes that share disorders with SSFA2           About GenesLikeMe

    Genetic Association Database (GAD): SSFA2

    Export disorders for SSFA2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SSFA2 gene, integrated from 10 sources (see all 33):
    (articles sorted by number of sources associating them with SSFA2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human cleavage signal-1 protein; cDNA cloning, transcription and immunological analysis. (PubMed id 1555770)1, 2, 3, 9 Javed A.A. and Naz R.K. (Gene 1992)
    2. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W.... Wilson R.K. (Nature 2005)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Deregulated expression of KRAP, a novel gene encoding actin- interacting protein, in human colon cancer cells. (PubMed id 14673706)1, 2 Inokuchi J.... Shirasawa S. (J. Hum. Genet. 2004)
    7. Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. (PubMed id 11572484)1, 2 Nagase T.... Ohara O. (DNA Res. 2001)
    8. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)
    9. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    10. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 6744 HGNC: 11319 AceView: SSFA2 Ensembl:ENSG00000138434 euGenes: HUgn6744
    ECgene: SSFA2 H-InvDB: SSFA2

    (According to HUGE)
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    HUGE: KIAA1927

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SSFA2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SSFA2 gene:
    Search GeneIP for patents involving SSFA2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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