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SSBP2 Gene

protein-coding   GIFtS: 55
GCID: GC05M080751

Single-Stranded DNA Binding Protein 2

(Previous name: single-stranded DNA-binding protein 2)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Single-Stranded DNA Binding Protein 21 2
Single-Stranded DNA-Binding Protein 21 2
Sequence-Specific Single-Stranded-DNA-Binding Protein 22 3
HSPC1162
SOSS-B22
SSDP23

External Ids:    HGNC: 158311   Entrez Gene: 236352   Ensembl: ENSG000001456877   OMIM: 6073895   UniProtKB: P818773   
ORGUL members:         

Export aliases for SSBP2 gene to outside databases

Previous GC identifers: GC05M079501 GC05M080954 GC05M080754 GC05M080799 GC05M075924


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SSBP2 Gene:
SSBP2 is a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome
stability (Huang et al., 2009) (PubMed 19683501).(supplied by OMIM, Feb 2010)

GeneCards Summary for SSBP2 Gene:
SSBP2 (single-stranded DNA binding protein 2) is a protein-coding gene. Diseases associated with SSBP2 include acute lymphocytic leukemia, and lissencephaly. GO annotations related to this gene include single-stranded DNA binding. An important paralog of this gene is SSBP4.

Gene Wiki entry for SSBP2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000005.10  NC_018916.2  NT_034772.7  
Regulatory elements:
   Regulatory transcription factor binding sites in the SSBP2 gene promoter:
         ER-alpha   COMP1   FOXO3a   FOXO3   LUN-1   FOXO3b   GATA-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSSBP2 promoter sequence
   Search Chromatin IP Primers for SSBP2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SSBP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q14.1   Ensembl cytogenetic band:  5q14.1   HGNC cytogenetic band: 5q14.1

SSBP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SSBP2 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M080751:  view genomic region     (about GC identifiers)

Start:
80,708,840 bp from pter      End:
81,047,616 bp from pter
Size:
338,777 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SSBP2_HUMAN, P81877 (See protein sequence)
Recommended Name: Single-stranded DNA-binding protein 2  
Size: 361 amino acids; 37828 Da
Secondary accessions: B2R5W1 B7Z1J2 B7Z2L9 B7Z665 D6RH18 E9PB74 E9PDA8 Q8N2Q2 Q9BWW6 Q9Y4T7
Alternative splicing: 5 isoforms:  P81877-1   P81877-2   P81877-3   P81877-4   P81877-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SSBP2: NX_P81877

Explore proteomics data for SSBP2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys21
  • Modification sites at PhosphoSitePlus

  • See SSBP2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (6 alternative transcripts): 
    NP_001243661.1  NP_001243662.1  NP_001243663.1  NP_001243664.1  NP_001243665.1  NP_036578.2  

    ENSEMBL proteins: 
     ENSP00000322977   ENSP00000422961   ENSP00000426183   ENSP00000425146   ENSP00000424561  
     ENSP00000423969   ENSP00000424657   ENSP00000422756  

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    Novus Biologicals SSBP2 Protein
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    Cloud-Clone Corp. CLIAs for SSBP2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR008116 SSDP_DNA-bd
     IPR006594 LisH_dimerisation

    Graphical View of Domain Structure for InterPro Entry P81877

    ProtoNet protein and cluster: P81877

    2 Blocks protein domains:
    IPB006594 Lissencephaly type-1-like homology motif
    IPB007591 Single-stranded DNA-binding protein


    UniProtKB/Swiss-Prot: SSBP2_HUMAN, P81877
    Similarity: Contains 1 LisH domain


    SSBP2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003697single-stranded DNA binding NAS12079286
    GO:0005515protein binding ----
         
    SSBP2 for ontologies           About GeneDecksing


    Phenotypes:
         7 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ssbp2):
     cardiovascular system  hematopoietic system  immune system  mortality/aging  renal/urinary system 
     skeleton  tumorigenesis 

    SSBP2 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Ssbp2tm1Lana for SSBP2

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SSBP2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SSBP2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SSBP2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SSBP2

    miRNA
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    Block miRNA regulation of human, mouse, rat SSBP2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SSBP2 (see all 29):
    hsa-miR-30c hsa-miR-3689b hsa-miR-345 hsa-miR-3607-5p hsa-miR-520d-5p hsa-miR-513a-5p hsa-miR-3678-5p hsa-miR-134
    SwitchGear 3'UTR luciferase reporter plasmidSSBP2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SSBP2

    Gene Editing
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SSBP2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SSBP2_HUMAN, P81877: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IDA--

    SSBP2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SSBP2
    Interactions:

        Search GeneGlobe Interaction Network for SSBP2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for SSBP2 (P818772, 3 ENSP000003229774) via UniProtKB, MINT, STRING, and/or I2D (see all 50)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LDB1Q86U702, 3, ENSP000003924664MINT-67628 I2D: score=6 STRING: ENSP00000392466
    IL36RNQ9UBH02, 3, ENSP000002592124MINT-67709 I2D: score=5 STRING: ENSP00000259212
    TAL1P175423, ENSP000002943394I2D: score=2 STRING: ENSP00000294339
    DYRK2Q926303, ENSP000003421054I2D: score=1 STRING: ENSP00000342105
    LHX2P504583, ENSP000003627174I2D: score=1 STRING: ENSP00000362717
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-templated NAS12079286

    SSBP2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SSBP2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SSBP2 gene (6 alternative transcripts): 
    NM_001256732.1  NM_001256733.1  NM_001256734.1  NM_001256735.1  NM_001256736.1  NM_012446.3  

    Unigene Cluster for SSBP2:

    Single-stranded DNA binding protein 2
    Hs.102735  [show with all ESTs]
    Unigene Representative Sequence: NM_001256732
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19):
    ENST00000320672(uc003khn.3 uc003kho.3 uc003khp.3 uc011ctp.2 uc011ctq.2 uc011ctr.2)
    ENST00000509053 ENST00000514493 ENST00000504985 ENST00000512923 ENST00000510060
    ENST00000505980 ENST00000515395 ENST00000513785 ENST00000504136 ENST00000509743
    ENST00000507655 ENST00000507472 ENST00000509013 ENST00000504174 ENST00000512098
    ENST00000506960 ENST00000507968
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SSBP2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SSBP2 (see all 29):
    hsa-miR-30c hsa-miR-3689b hsa-miR-345 hsa-miR-3607-5p hsa-miR-520d-5p hsa-miR-513a-5p hsa-miR-3678-5p hsa-miR-134
    SwitchGear 3'UTR luciferase reporter plasmidSSBP2 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for SSBP2
    Predesigned siRNA for gene silencing in human, mouse, rat SSBP2
    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SSBP2
    Primer
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    OriGene qPCR primer pairs and template standards for SSBP2
    OriGene qSTAR qPCR primer pairs in human, mouse for SSBP2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SSBP2
      QuantiTect SYBR Green Assays in human, mouse, rat SSBP2
      QuantiFast Probe-based Assays in human, mouse, rat SSBP2

    Additional mRNA sequence: 

    AF077048.1 AF161465.1 AK074537.1 AK293544.1 AK294864.1 AK297494.1 AK299858.1 AK312337.1 
    AL080076.1 BC017020.1 CR936787.1 

    14 DOTS entries:

    DT.116221  DT.100663167  DT.100810367  DT.91759265  DT.100717230  DT.87046177  DT.100027979  DT.309693 
    DT.120810534  DT.100773572  DT.100810362  DT.120810582  DT.91759268  DT.40109593 

    Selected AceView cDNA sequences (see all 232):

    CR605486 CR600282 BM923177 BX397790 AA953439 CA393157 AL537293 BQ575040 
    AL709113 CR613597 CA393473 AL538970 CB250676 BM763659 BI517313 CD676136 
    BF446687 BM459374 AA458637 BM800600 CA426910 CA444691 BC017020 N26986 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SSBP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATAGGAATA
    SSBP2 Expression
    About this image


    SSBP2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Gonad (Reproductive System)
             Primordial Germ Cells Primitive Gonad
     
     Limb (Muscoskeletal System)
             Limb Muscle Progenitor Cells Forelimb Myotome
     
     Skeletal Muscle (Muscoskeletal System)
             Limb Muscle Progenitor Cells Forelimb Myotome
     
     Uterus (Reproductive System)
     
     Thyroid (Endocrine System)
    SSBP2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SSBP2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.102735

    UniProtKB/Swiss-Prot: SSBP2_HUMAN, P81877
    Tissue specificity: Ubiquitous

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SSBP2 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ssbp21 , 5 single-stranded DNA binding protein 21, 5 95.66(n)1
    99.72(a)1
      13 (47.43 cM)5
    669701  NM_024272.41  NP_077234.21 
     914602835 
    chicken
    (Gallus gallus)
    Aves SSBP21 single-stranded DNA binding protein 2 91.85(n)
    98.91(a)
      770958  XM_004949454.1  XP_004949511.1 
    lizard
    (Anolis carolinensis)
    Reptilia SSBP26
    single-stranded DNA binding protein 2
    97(a)
    1 ↔ 1
    2(17560428-17690683)
    African clawed frog
    (Xenopus laevis)
    Amphibia ssbp2-prov2 single-stranded DNA binding protein 2 82.83(n)    BC042259.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC7980861 single-stranded DNA-binding protein 2-like 74.67(n)
    86(a)
      798086  XM_001338506.5  XP_001338542.4 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG71873 single-stranded DNA binding 91(a)   90F1   --
    worm
    (Caenorhabditis elegans)
    Secernentea sam-106
    Protein SAM-10, isoform a
    20(a)
    1 → many
    II(13322013-13330825) WBGene00012990


    ENSEMBL Gene Tree for SSBP2 (if available)
    TreeFam Gene Tree for SSBP2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SSBP2 gene
    SSBP42  SSBP32  
    3 SIMAP similar genes for SSBP2 using alignment to 4 protein entries:     SSBP2_HUMAN (see all proteins):
    SSDP4    SSBP3    SSBP4

    SSBP2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SSBP2
    PGOHUM00000243267


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SSBP2 (see all 5718)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1924654621,2
    --80712750(+) ATCTCA/GGCTCA 6 -- ds50010--------
    rs1828719621,2
    --80712885(+) CACCAG/TGTTGG 6 -- ds50010--------
    rs1176200861,2
    C,F--80713033(+) TCAGCA/GACTGA 6 -- ds50011Minor allele frequency- G:0.03EA 120
    rs119496971,2
    C,F,A,H--80713096(+) ATGTGT/GTGTAT 6 -- ds5001 ese323Minor allele frequency- G:0.41NS EA NA WA CSA 2702
    rs1860056681,2
    --80713293(+) ATTTAA/GTATGT 6 -- ut310--------
    rs786686881,2
    C--80713305(+) CAATGC/TAGCAA 6 -- ut313Minor allele frequency- T:0.15CSA WA NA 240
    rs10547991,2
    C,F--80713340(-) TACACG/ATCATC 6 -- ut31 ese34Minor allele frequency- A:0.01NA 144
    rs1165805671,2
    F--80713365(+) AACAGG/ATAGTA 6 -- ut311Minor allele frequency- A:0.01WA 118
    rs1449108261,2
    C--80713390(+) CACGAA/GTGCAT 6 -- ut310--------
    rs792806651,2
    --80713440(+) TCTTAC/TTACAA 6 -- ut310--------

    HapMap Linkage Disequilibrium report for SSBP2 (80708840 - 80958840 bp, first 250kb of SSBP2)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for SSBP2 (see all 28):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2668722CNV Deletion23128226
    esv2730386CNV Deletion23290073
    esv2730385CNV Deletion23290073
    esv4616CNV Deletion18987735
    esv2730382CNV Deletion23290073
    esv2524327CNV Deletion19546169
    esv993941CNV Deletion20482838
    esv1711772CNV Deletion17803354
    esv2730383CNV Deletion23290073
    esv2125406CNV Deletion18987734

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 607389    OMIM disorders: --

    11 diseases for SSBP2:    
    About MalaCards
    acute lymphocytic leukemia    lissencephaly    myeloproliferative disorder    anorexia nervosa
    esophageal squamous cell carcinoma    squamous cell carcinoma    esophagitis    myeloid leukemia
    leukemia    prostate cancer    prostatitis


    SSBP2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SSBP2
    Human Genome Epidemiology (HuGE) Navigator: SSBP2 (1 document)

    Export disorders for SSBP2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SSBP2 gene, integrated from 10 sources (see all 34):
    (articles sorted by number of sources associating them with SSBP2)
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    1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (Genome Res. 2001)
    2. SSBP2 variants are associated with survival in glioblastoma patients. (PubMed id 22472174)1, 4 Xiao Y....Wrensch M.R. (Clin. Cancer Res. 2012)
    3. A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa. (PubMed id 21079607)1, 4 Wang K....Hakonarson H. (Mol. Psychiatry 2011)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. A novel, evolutionarily conserved gene family with putative sequence- specific single-stranded DNA-binding activity. (PubMed id 12079286)1, 2 Castro P.D.... Nagarajan L. (Genomics 2002)
    8. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (Proc. Natl. Acad. Sci. U.S.A. 2000)
    9. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 3 Zhang Q.-H.... Chen Z. (Genome Res. 2000)
    10. Adenoviral E1B55K oncoprotein sequesters candidate leukemia suppressor sequence-specific single-stranded DNA-binding protein 2 into aggresomes. (PubMed id 17311003)1, 9 Fleisig H.B....Nagarajan L. (Oncogene 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23635 HGNC: 15831 AceView: SSBP2 Ensembl:ENSG00000145687 euGenes: HUgn23635
    ECgene: SSBP2 H-InvDB: SSBP2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SSBP2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SSBP2 gene:
    Search GeneIP for patents involving SSBP2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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