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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SSBP1 Gene

protein-coding   GIFtS: 59
GCID: GC07P141442

Single-Stranded DNA Binding Protein 1, Mitochondrial

(Previous names: single-stranded DNA-binding protein, single-stranded DNA...)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Single-Stranded DNA Binding Protein 1, Mitochondrial1 2     Single-Stranded DNA-Binding Protein1
SSBP2 3 5     SOSS-B12
Mt-SSB2 3     mtSSB2
PWP1-Interacting Protein 172 3     Single-Stranded DNA-Binding Protein, Mitochondrial2
Single-Stranded DNA Binding Protein 11     MtSSB3

External Ids:    HGNC: 113171   Entrez Gene: 67422   Ensembl: ENSG000001060287   OMIM: 6004395   UniProtKB: Q048373   

Export aliases for SSBP1 gene to outside databases

Previous GC identifers: GC07P139708 GC07P140768 GC07P140845 GC07P140891 GC07P141084 GC07P141440 GC07P135734


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SSBP1 Gene:
SSBP1 is a housekeeping gene involved in mitochondrial biogenesis (Tiranti et al., 1995 (PubMed 7789991)). It is
also a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability
(Huang et al., 2009) (PubMed 19683501).(supplied by OMIM, Feb 2010)

GeneCards Summary for SSBP1 Gene: 
SSBP1 (single-stranded DNA binding protein 1, mitochondrial) is a protein-coding gene. Diseases associated with SSBP1 include bovine spongiform encephalopathy, and herpes simplex, and among its related super-pathways are Gap-filling DNA repair synthesis and ligation in TC-NER and Homologous recombination. GO annotations related to this gene include chromatin binding and single-stranded DNA binding.

UniProtKB/Swiss-Prot: SSBP_HUMAN, Q04837
Function: This protein binds preferentially and cooperatively to ss-DNA. Probably involved in mitochondrial DNA
replication. Associates with mitochondrial DNA

Gene Wiki entry for SSBP1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_007914.15  NC_018918.2  NT_079596.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SSBP1 gene promoter:
         Pbx1a   HTF   GCNF   LCR-F1   Roaz   AREB6   GCNF-1   FOXJ2 (long isoform)   FOXJ2   GCNF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSSBP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for SSBP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SSBP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q34   Ensembl cytogenetic band:  7q34   HGNC cytogenetic band: 7q34

SSBP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SSBP1 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P141442:  view genomic region     (about GC identifiers)

Start:
141,438,121 bp from pter      End:
141,487,722 bp from pter
Size:
49,602 bases      Orientation:
plus strand

2 alternative locations:
Chr7+,NW_003315922 110,976-118,190      Chr7+,CRA_TCAG 140,775,895-140,787,976     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SSBP_HUMAN, Q04837 (See protein sequence)
Recommended Name: Single-stranded DNA-binding protein, mitochondrial precursor  
Size: 148 amino acids; 17260 Da
Subunit: Homotetramer (By similarity)
Subcellular location: Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid
3 PDB 3D structures from and Proteopedia for SSBP1:
1S3O (3D)        2DUD (3D)        3ULL (3D)    

Explore the universe of human proteins at neXtProt for SSBP1: NX_Q04837

Explore proteomics data for SSBP1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q04837

  • SSBP1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SSBP1 Protein Expression
    REFSEQ proteins (5 alternative transcripts): 
    NP_001243439.1  NP_001243440.1  NP_001243441.1  NP_001243442.1  NP_003134.1  

    ENSEMBL proteins: 
     ENSP00000265304   ENSP00000419541   ENSP00000418068   ENSP00000420485   ENSP00000419579  
     ENSP00000419388   ENSP00000418181   ENSP00000419665  

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    Cloud-Clone Corp. Proteins for SSBP1 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA--
    GO:0042645mitochondrial nucleoid IDA18063578

    SSBP1 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for SSBP1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR012340 NA-bd_OB-fold
     IPR011344 ssDNA-bd
     IPR000424 Primosome_PriB/ssb

    Graphical View of Domain Structure for InterPro Entry Q04837

    ProtoNet protein and cluster: Q04837

    2 Blocks protein domains:
    IPB000424 Single-strand binding protein
    IPB011344 Single-strand binding protein


    UniProtKB/Swiss-Prot: SSBP_HUMAN, Q04837
    Similarity: Contains 1 SSB domain


    SSBP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SSBP_HUMAN, Q04837
    Function: This protein binds preferentially and cooperatively to ss-DNA. Probably involved in mitochondrial DNA
    replication. Associates with mitochondrial DNA

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003682chromatin binding IDA18063578
    GO:0003697single-stranded DNA binding IEA--
    GO:0005515protein binding IPI--
         
    SSBP1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SSBP1:
     Increased circadian period len 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Ssbp1):
     mortality/aging 

    SSBP1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SSBP1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SSBP1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SSBP1 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SSBP1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Lagging Strand Synthesis
    DNA replication0.63
    Mismatch repair0.56
    2Homologous recombination
    Homologous recombination0.40

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    3         Kegg Pathways  (Kegg details for SSBP1):
        DNA replication
    Mismatch repair
    Homologous recombination


    SSBP1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SSBP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/392 Interacting proteins for SSBP1 (Q048371, 2, 3 ENSP000002653044) via UniProtKB, MINT, STRING, and/or I2D (see all 392)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    YWHAQP273482, 3, ENSP000002380814MINT-8395092 I2D: score=1 STRING: ENSP00000238081
    ICT1Q141972, 3, ENSP000003015854MINT-8079030 I2D: score=1 STRING: ENSP00000301585
    AGO4Q9HCK53, ENSP000003623064I2D: score=2 STRING: ENSP00000362306
    H2AFXP161043, ENSP000003643104I2D: score=2 STRING: ENSP00000364310
    GRB2P629933, ENSP000003390074I2D: score=1 STRING: ENSP00000339007
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006260DNA replication IEA--
    GO:0051096positive regulation of helicase activity IDA12975372
    GO:0070584mitochondrion morphogenesis IEA--

    SSBP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SSBP1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SSBP1 (SSBP)

    1 Novoseek inferred chemical compound relationship for SSBP1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    cisplatin 4.47 1 9593724 (1)

    Search CenterWatch for drugs/clinical trials and news about SSBP1 / SSBP

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SSBP1 gene (5 alternative transcripts): 
    NM_001256510.1  NM_001256511.1  NM_001256512.1  NM_001256513.1  NM_003143.2  

    Unigene Cluster for SSBP1:

    Single-stranded DNA binding protein 1, mitochondrial
    Hs.490394  [show with all ESTs]
    Unigene Representative Sequence: BC008402
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000265304(uc003vwo.1 uc010lnp.1) ENST00000496622 ENST00000498107
    ENST00000489378(uc011kri.1) ENST00000469123 ENST00000467681 ENST00000465582
    ENST00000461433 ENST00000463093 ENST00000465167 ENST00000468267 ENST00000484178
    ENST00000473783 ENST00000481508
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SSBP1

    Additional mRNA sequence: 

    AF277319.1 AK294393.1 AK313033.1 BC000895.1 BC008402.1 BC093054.1 M94556.1 NR_046269.1 

    22 DOTS entries:

    DT.100827331  DT.121048312  DT.449737  DT.121048295  DT.95204991  DT.121048365  DT.100012076  DT.40275402 
    DT.100827329  DT.121048324  DT.121048493  DT.40133230  DT.92452888  DT.97862533  DT.101986267  DT.121048373 
    DT.454358  DT.86994620  DT.95204990  DT.100664999  DT.418620  DT.95228622 

    24/540 AceView cDNA sequences (see all 540):

    AA421436 BI518503 BQ231037 AI198927 BE904325 BQ222279 BU188894 BU624852 
    BQ219468 AI951590 BX495149 BQ446863 BE906191 BU156397 BU631003 BU181926 
    BQ230869 BM548943 BM806271 NM_003143 BU153613 BE891991 BU188226 BQ215716 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for SSBP1 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9
    SP1:                                            -     -                                   -         
    SP2:                    -     -     -           -     -                                             
    SP3:                          -     -           -     -                                             
    SP4:                                -           -     -                                             
    SP5:                    -     -     -                                                               


    ECgene alternative splicing isoforms for SSBP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SSBP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATAATCTTT
    SSBP1 Expression
    About this image


    See SSBP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SSBP1

    SOURCE GeneReport for Unigene cluster: Hs.490394
        SABiosciences Custom PCR Arrays for SSBP1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SSBP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SSBP1 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ssbp11 , 5 single-stranded DNA binding protein 11, 5 90.25(n)1
    92.52(a)1
      6 (18.82 cM)5
    3817601  NM_212468.31  NP_997633.11 
     404713525 
    chicken
    (Gallus gallus)
    Aves SSBP11 single-stranded DNA binding protein 1 76.87(n)
    80.27(a)
      418122  XM_416355.3  XP_416355.1 
    lizard
    (Anolis carolinensis)
    Reptilia SSBP16
    Single-stranded DNA-binding protein
    86(a)
    1 ↔ 1
    5(16186384-16196366)
    African clawed frog
    (Xenopus laevis)
    Amphibia XL2 mitochondrial DNA specific single-stranded DNA binding more 74.18(n)    X59285.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.176262 Transcribed sequence with moderate similarity to protein more 79.03(n)    BQ074846.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta mtSSB1 mitochondrial single stranded DNA-binding protein 47.58(n)
    44.27(a)
      41968  NM_001038968.1  NP_001034057.1 


    ENSEMBL Gene Tree for SSBP1 (if available)
    TreeFam Gene Tree for SSBP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SSBP1 gene

    SSBP1 for paralogs           About GeneDecksing


    4 Pseudogenes.org Pseudogenes for SSBP1
    PGOHUM00000238384 PGOHUM00000244636 PGOHUM00000240351 PGOHUM00000243405


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/253 SNPs in SSBP1 are shown (see all 253)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1389946701,2
    --141440105(+) TTTTTA/GTATTA 6 -- int10--------
    rs1902437281,2
    --141440198(+) TTTACA/TGGAGC 6 -- int10--------
    rs752514621,2
    C,F--141440235(+) GCTTCG/CGGAAA 6 -- int11Minor allele frequency- C:0.03EA 120
    rs1414718551,2
    --141440252(+) GCATTA/GGTGTC 6 -- int10--------
    rs1508645861,2
    --141440263(+) AAGGGC/TCCTGG 6 -- int10--------
    rs69755081,2
    C,F,A,H--141440322(+) gatgcA/Cgtctc 6 -- int15Minor allele frequency- C:0.01NS EA WA 536
    rs1831843911,2
    --141440497(+) CAGTCG/TAGTCT 6 -- int10--------
    rs1884686921,2
    --141440544(+) TTTTGA/TTGCAC 6 -- int10--------
    rs1382025831,2
    C--141440551(+) GCACTA/GAAAAC 6 -- int10--------
    rs175222581,2
    C,F--141440619(+) GCTGTT/GTAATT 6 -- int14Minor allele frequency- G:0.02NA 260

    HapMap Linkage Disequilibrium report for SSBP1 (141438121 - 141487722 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for SSBP1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv34135CNV Loss18971310

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 600439    OMIM disorders: --

    15 diseases for SSBP1:    About MalaCards
    bovine spongiform encephalopathy    herpes simplex    autistic disorder    scrapie
    mitochondrial disorders    encephalomyopathy    chronic myeloid leukemia    diabetes mellitus
    myeloid leukemia    pneumonia    hepatocellular carcinoma    hepatitis
    prostate cancer    leukemia    prostatitis

    1 disease from the University of Copenhagen DISEASES database for SSBP1:
    Scrapie

    SSBP1 for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for SSBP1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    herpes simplex 48.6 8 12645567 (2), 9593724 (1), 8063811 (1), 9446572 (1) (see all 7)

    Genetic Association Database (GAD): SSBP1
    Human Genome Epidemiology (HuGE) Navigator: SSBP1 (1 document)

    Export disorders for SSBP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SSBP1 gene, integrated from 9 sources (see all 101):
    (articles sorted by number of sources associating them with SSBP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Chromosomal localization of mitochondrial transcription factor A (TCF6), single-stranded DNA-binding protein (SSBP), and endonuclease G (ENDOG), three human housekeeping genes involved in mitochondrial biogenesis. (PubMed id 7789991)1, 3, 9 Tiranti V.... Zeviani M. (1995)
    2. Cloning of human and rat cDNAs encoding the mitochondrial single- stranded DNA-binding protein (SSB). (PubMed id 8482537)1, 2, 9 Tiranti V.... Zeviani M. (1993)
    3. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    4. The layered structure of human mitochondrial DNA nucleoids. (PubMed id 18063578)1, 2 Bogenhagen D.F....Burke S. (2008)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Crystal structure of human mitochondrial single-stranded DNA binding protein at 2.4-A resolution. (PubMed id 9033597)1, 2 Yang C.... Kang C. (1997)
    7. Epstein-Barr virus immediate-early protein Zta co-opts mitochondrial single-stranded DNA binding protein to promote viral and inhibit mitochondrial DNA replication. (PubMed id 18305033)1, 9 Wiedmer A....Lieberman P.M. (2008)
    8. Regulation of mitochondrial D-loops by transcription factor A and single-stranded DNA-binding protein. (PubMed id 11964388)1, 9 Takamatsu C....Kang D. (2002)
    9. Immunocytochemical localization of mitochondrial single-stranded DNA-binding protein in mitochondria-rich cells of normal and neoplastic human tissue. (PubMed id 11556757)1, 9 Muller-Hocker J....Li K. (2001)
    10. CKS proteins protect mitochondrial genome integrity b y interacting with mitochondrial single-stranded DNA-binding protein. (PubMed id 19786724)1, 9 Radulovic M....Yu V.P. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6742 HGNC: 11317 AceView: SSBP1 Ensembl:ENSG00000106028 euGenes: HUgn6742
    ECgene: SSBP1 Kegg: 6742 H-InvDB: SSBP1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SSBP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SSBP1 gene:
    Search GeneIP for patents involving SSBP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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