SSB Gene
protein-coding GIFtS: 61
GCID: GC02P170619
|
|
Sjogren syndrome antigen B (autoantigen La)
| |
Aliases
for SSB gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Sjogren Syndrome Antigen B (Autoantigen La)1 2 | | Autoantigen La2 | | LARP31 2 5 | | La Ribonucleoprotein Domain Family, Member 32 | | La1 2 | | Lupus La Antigen2 | | La Autoantigen2 3 | | Lupus La Protein2 | | Sjoegren Syndrome Type B Antigen2 3 | | SS-B/La Protein2 | | SS-B2 3 | | La Ribonucleoprotein3 |
Export aliases for SSB gene to outside databasesPrevious GC identifers: GC02P168707 GC02P169196 GC02P170857 GC02P170480 GC02P170363 GC02P162543 |
Summaries
for SSB gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SSB:
The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protectingpoly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends ofpre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus.Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupuserythematosus. (provided by RefSeq, Nov 2011)
UniProtKB/Swiss-Prot: LA_HUMAN, P05455Function: Binds to the 3' poly(U) terminii of nascent RNA polymerase III transcripts, protecting them from exonucleasedigestion and facilitating their folding and maturation
Gene Wiki entry for SSB (Sjogren syndrome antigen B)
|
Genomic Views
for SSB gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_005403.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SSB gene promoter:
TBP C/EBPbeta p53 AP-1 ATF-2 Meis-1b POU2F1 POU2F1a c-Jun En-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for SSB
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SSB |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q31.1 Ensembl cytogenetic band: 2q31.1 HGNC cytogenetic band: 2q31.1SSB Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P170619: view genomic region
(about GC identifiers)
Start:
|
170,648,443 bp from pter |
End:
|
170,668,575 bp from pter |
Size:
|
20,133 bases |
Orientation:
|
plus strand |
|
Proteins
for SSB gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: LA_HUMAN, P05455 (See
protein sequence)Recommended Name: Lupus La protein Size: 408 amino acids; 46837 Da
Subunit: Interacts with DDX15. May interact with RUFY1
Subcellular location: Nucleus (Probable)
Miscellaneous: Sera from patients with systemic lupus erythematosus (SLE) often contain antibodies that react with thenormal cellular La protein as if this antigen was foreign
6/9 PDB 3D structures from  and Proteopedia  for SSB (see all 9):1OWX (3D)
1S79 (3D)
1S7A (3D)
1YTY (3D)
1ZH5 (3D)
2VOD (3D)
Secondary accessions: Q15367 Q53XJ4Explore the universe of human proteins at neXtProt for SSB: NX_P05455
Post-translational modifications:
Phosphorylated. The phosphorylation sites are at the C-terminal part of the protein1
The N-terminus is blocked1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P05455
SSB Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_003133.1
ENSEMBL proteins: ENSP00000397029 ENSP00000260956 ENSP00000386524 ENSP00000395758 ENSP00000396890 ENSP00000386636
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- | | GO:0030529 | ribonucleoprotein complex |
IEA | -- |
SSB for ontologies About GeneDecksing
SSB Antibody Products:
Assay Products for SSB: |
Protein
Domains /
Families
for SSB gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SSB for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry P05455ProtoNet protein and cluster: P05455 2 Blocks protein families: IPB000504 RNA-binding region RNP-1 (RNA recognition motif) IPB002344 Lupus La protein signature
UniProtKB/Swiss-Prot: LA_HUMAN, P05455Similarity: Contains 1 HTH La-type RNA-binding domainSimilarity: Contains 1 RRM (RNA recognition motif) domain |
Function
for SSB gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: LA_HUMAN, P05455Function: Binds to the 3' poly(U) terminii of nascent RNA polymerase III transcripts, protecting them from exonucleasedigestion and facilitating their folding and maturation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SSB (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SSB (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SSB (NM_003142) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SSB | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SSB |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SSB |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
SSB for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for SSB:
Animal Models:
Mouse knock-out Ssbtm1Rjma for SSB
2 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Ssb):
SSB for phenotypes About GeneDecksing
|
Pathways & Interactions
for SSB gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Systemic lupus erythematosus | | | 2 | Translational Control | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Cell Signaling Technology (CST) Pathway for SSB
1 
Kegg Pathway (Kegg details for SSB):
SSB for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SSB
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/100 Interacting proteins for SSB (P054552, 3 ENSP000002609564) via UniProtKB, MINT, STRING, and/or I2D (see all 100)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
SSB for ontologies About GeneDecksing
|
Drugs & Compounds
for SSB gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SSB for compounds About GeneDecksing
 Browse Tocris compounds for SSB
1 Novoseek chemical compound relationship for SSB gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| atp |
5.16 |
2 |
8454877 (1) |
Search CenterWatch for drugs/clinical trials and news about SSB / LA
|
Transcripts
for SSB gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SSB gene: NM_003142.4 Unigene Cluster for SSB: Sjogren syndrome antigen B (autoantigen La) Hs.632535 [show with all ESTs]Unigene Representative Sequence: AK12481113 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000422006 ENST00000260956(uc002ufk.3) ENST00000409005 ENST00000413002
ENST00000417292 ENST00000461708 ENST00000409333(uc002ufm.3) ENST00000468600
ENST00000474273 ENST00000465871 ENST00000470621 ENST00000490914 ENST00000494051
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SSB (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SSB (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SSB (NM_003142) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SSB | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SSB |
Additional cDNA sequence: AB451228.1 AB451351.1 AK124811.1 BC001289.1 BC020818.1 BT009862.1 D28394.1 DQ185046.1 J04205.1 M20328.1 X13697.1 X14684.1 X69804.1 24/37 DOTS entries (see all 37): DT.100827681 DT.450195 DT.95374444 DT.92324971 DT.95374443 DT.86843626 DT.121009153 DT.100827688 DT.100827696 DT.121406305 DT.121009120 DT.100827693 DT.100827697 DT.100827700 DT.121009195 DT.91751776 DT.100827691 DT.121009128 DT.121009202 DT.91720683 DT.91728862 DT.91809273 DT.91849480 DT.91929640 24/308 AceView cDNA sequences (see all 308): BM729231 CA411696 CB159655 AL549494 BP370612 CR620968 CD106796 AA160174 CR625880 BQ010023 BE856256 AA479280 BU608941 AW002784 BM679923 BP362980 CD722732 BQ013645 CD676196 AW272731 BQ427764 CR599289 BQ478278 BM922633
GeneLoc Exon Structure
|
Expression
for SSB gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SSB expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATGAAAATGG
About this image
See SSB Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SSB
SOURCE GeneReport for Unigene cluster: Hs.632535
SABiosciences Expression via Pathway-Focused PCR Array including SSB:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SSB
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SSB | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SSB | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SSB | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SSB |
Orthologs
for SSB gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SSB gene from 8/27 species (see all 27) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
SSB1 |
Sjogren syndrome antigen B (autoantigen La) |
75.66(n)
75.25(a) |
|
395268 NM_001193669.1 NP_001180598.1 |
lizard
(Anolis carolinensis) |
Reptilia |
SSB6 |
-- |
67(a) |
1 ↔ 1 |
GL343362.1(559798-570970) |
African clawed frog
(Xenopus laevis) |
Amphibia |
MGC528762 |
similar to Lupus LA protein homolog B |
72.39(n) |
|
BC046654.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufb17f112 |
wufb17f11 |
73.27(n) |
|
321504 BC045392.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
La1 , 3 |
RNA binding3
La autoantigen-like1 |
35(a)3
46.69(n)1
39.16(a)1 |
|
2 38C53
353051 NM_057666.41 NP_477014.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
C44E4.41 , 3 |
RNA-binding protein3
Protein C44E4.41 |
35(a)3
46.91(n)1
35.11(a)1 |
|
I(4634111-4635403)3
1720701 NM_059010.31 NP_491411.11 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
La11 |
La protein 1 |
43.85(n)
30.94(a) |
|
829408 NM_119425.4 NP_567904.1 |
rice
(Oryza sativa) |
Liliopsida |
Os02g06104001 |
hypothetical protein |
43.4(n)
31.77(a) |
|
4329949 NM_001053933.1 NP_001047398.1 |
ENSEMBL Gene Tree for SSB (if available)
TreeFam Gene Tree for SSB (if available) |
Paralogs
for SSB gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SSB gene
- LARP72
3 SIMAP similar genes for SSB using alignment to 6 protein entries: LA_HUMAN (see all proteins):LARP1 LARP1B LARP7
SSB for paralogs About GeneDecksing
5/9 Pseudogenes.org Pseudogenes for SSB (see all 9)
PGOHUM00000239754 PGOHUM00000247080 PGOHUM00000237461 PGOHUM00000244212 PGOHUM00000238252
|
Genomic Variants
for SSB gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SSB (170648443 - 170668575 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for SSB
2 CNVs: 32382 90125 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SSB |
|
Disorders
/ Diseases
for SSB gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SSB for disorders About GeneDecksing
OMIM gene information: 109090
OMIM disorders: --
20/25  diseases for SSB (see all 25): About MalaCardssjogren's syndrome systemic lupus erythematosus lupus erythematosus hepatitis c
hepatitis mixed connective tissue disease connective tissue disease dry eye syndrome
heart block congenital heart block japanese encephalitis cutaneous lupus erythematosus
conjunctival disease parotitis sialadenitis hypergammaglobulinemia
hepatitis a encephalitis keratoconjunctivitis polymyositis
9 diseases from the University of Copenhagen DISEASES database for SSB:Congenital heart block Systemic lupus erythematosus Sjogren's syndrome Dry eye syndrome
Cutaneous lupus erythematosus Keratoconjunctivitis Von Willebrand's disease Mixed connective tissue disease
Conjunctival disease 8 Novoseek disease relationships for SSB gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| sjogrens syndrome primary |
74.7 |
2 |
16178869 (1), 12528117 (1) |
| sjogrens syndrome |
67 |
5 |
1688881 (1), 1718461 (1), 8454877 (1), 20380108 (1) |
| lupus erythematosus systemic |
59.1 |
4 |
9650095 (1), 12691262 (1), 1688881 (1), 16014550 (1) |
| autoimmune response |
51.1 |
1 |
8454877 (1) |
| autoimmunity |
48.7 |
5 |
8920873 (1), 7542577 (1), 7846070 (1), 8454877 (1) |
| sclerosis systemic |
41.2 |
2 |
12691262 (1), 16014550 (1) |
| autoimmune diseases |
33.8 |
2 |
1718461 (1), 20380108 (1) |
| inflammation |
0 |
1 |
12528117 (1) |
Human Genome Epidemiology (HuGE) Navigator: SSB (18 documents)
Export disorders for SSB gene to outside databases
|
Publications
for SSB gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SSB gene, integrated from 9 sources (see all 157):
(articles sorted by number of sources associating them with SSB) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Structural analysis reveals conformational plasticity in the recognition of RNA 3' ends by the human La protein. (PubMed id 18547518)1, 2 Kotik-Kogan O....Curry S. (2008)
- Structural basis for recognition and sequestration of UUU(OH) 3' temini of nascent RNA polymerase III transcripts by La, a rheumatic disease autoantigen. (PubMed id 16387655)1, 2 Teplova M....Patel D.J. (2006)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- Structural analysis of cooperative RNA binding by the La motif and central RRM domain of human La protein. (PubMed id 15004549)1, 2 Alfano C....Conte M.R. (2004)
- Rabip4' is an effector of rab5 and rab4 and regulates transport through early endosomes. (PubMed id 14617813)1, 2 Fouraux M.A.... Pruijn G.J.M. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The human La (SS-B) autoantigen interacts with DDX15/hPrp43, a putative DEAH-box RNA helicase. (PubMed id 12458796)1, 2 Fouraux M.A.... Pruijn G.J.M. (2002)
- Phosphorylation of the human La antigen on serine 366 can regulate recycling of RNA polymerase III transcription complexes. (PubMed id 9054510)1, 2 Fan H.... Maraie R.J. (1997)
- Function of the mammalian La protein: evidence for its action in transcription termination by RNA polymerase III. (PubMed id 2470590)1, 2 Gottlieb E. and Steitz J.A. (1989)
- Ribonucleoprotein SS-B/La belongs to a protein family with consensus sequences for RNA-binding. (PubMed id 2468131)1, 2 Chan E.K.L.... Tan E.M. (1989)
|
External Searches for SSB gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SSB gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SSB gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SSB gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SSB | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SSB gene:
Search GeneIP for patents involving SSB
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SSB gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for SSB | | OriGene shRNA RFP for SSB | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SSB | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SSB | | | OriGene Protein Over-expression Lysate for SSB | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SSB | | OriGene 3'-UTR Clone for SSB | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SSB | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SSB | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for SSB | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SSB | | OriGene Custom Protein Services for SSB | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SSB | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SSB | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SSB | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SSB | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SSB | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SSB |
| |
 |  |  |  | |
| | Antibodies & Assays for SSB |
| | | | Search Tocris compounds for SSB |
| |  |  |  |  | | | | | | Recombinant Protein for SSB |
|
 |
 |
 |
 | | | SSB Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SSB |
|  |  |  | | | | ThermoFisher Antibodies for SSB |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SSB |
|
|
|
|
