Aliases for SSB Gene
Aliases for SSB Gene
External Ids for SSB Gene
- HGNC: 11316
- Entrez Gene: 6741
- Ensembl: ENSG00000138385
- OMIM: 109090
- UniProtKB: P05455
Previous GeneCards Identifiers for SSB Gene
- GC02P168707
- GC02P169196
- GC02P170619
- GC02P170857
- GC02P170480
- GC02P170363
- GC02P162543
- GC02P170649
Summaries for SSB Gene
-
The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein. [provided by RefSeq, Jun 2014]
GeneCards Summary for SSB Gene
SSB (Sjogren Syndrome Antigen B) is a Protein Coding gene. Diseases associated with SSB include Sjogren's Syndrome and Lupus Erythematosus. Among its related pathways are Gene Expression and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. GO annotations related to this gene include nucleic acid binding and RNA binding.
UniProtKB/Swiss-Prot for SSB Gene
-
Binds to the 3 poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation (PubMed:3192525, PubMed:2470590). In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:12384597).
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SSB Gene
Genomics for SSB Gene
Regulatory Elements for SSB Gene
Enhancers for SSB Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH02G169732 | 1 | ENCODE | 16.2 | -58.0 | -58034 | 2.0 | ATF1 FOXA2 CREB3L1 SIN3A ZNF48 GLIS2 ELK1 ZNF143 KLF13 KDM4B | SSB CYB5AP2 CCDC173 PHOSPHO2 GC02M169725 GC02P169749 |
| GH02G169709 | 1 | ENCODE | 16.1 | -80.4 | -80385 | 4.1 | ATF1 ZNF766 GATA2 ELK1 FOS KLF13 CAVIN1 ZNF592 MEF2D CREB3 | PHOSPHO2 SSB CCDC173 CYB5AP2 METTL5 UBR3 GC02P169728 KLHL23 |
| GH02G169528 | 1.1 | ENCODE dbSUPER | 11.4 | -263.5 | -263518 | 0.2 | HDAC1 CTCF SAP130 ARNT WRNIP1 ARID4B ZNF2 RAD21 CHAMP1 ZKSCAN1 | CYB5AP2 SSB METTL5 UBR3 FASTKD1 GC02M169527 |
| GH02G169682 | 1 | ENCODE | 11.1 | -108.6 | -108561 | 1.7 | FOXA2 MLX ARID4B DMAP1 YY1 SLC30A9 CBX5 MXD4 PPARG KAT8 | FASTKD1 PHOSPHO2 SSB CYB5AP2 GC02M169688 LOC100421474 |
| GH02G169703 | 0.6 | ENCODE | 15.6 | -86.8 | -86834 | 3.2 | JUND ZSCAN4 CEBPB HNF4A ZNF558 ZNF18 GABPA | PHOSPHO2 CCDC173 SSB CYB5AP2 KLHL23 GC02P169728 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around SSB on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for SSB Gene
- Chromosome:
- 2
- Start:
- 169,791,933 bp from pter
- End:
- 169,812,064 bp from pter
- Size:
- 20,132 bases
- Orientation:
- Plus strand
Genomic View for SSB Gene
Genes around SSB on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q31.1 by Ensembl
- 2q31.1 by Entrez Gene
- 2q31.1 by HGNC
SSB Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SSB Gene
Proteins for SSB Gene
-
Protein details for SSB Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P05455-LA_HUMAN
- Recommended name:
- Lupus La protein
- Protein Accession:
- P05455
- Q15367
- Q53XJ4
Protein attributes for SSB Gene
- Size:
- 408 amino acids
- Molecular mass:
- 46837 Da
- Quaternary structure:
-
- Interacts with DDX15. May interact with RUFY1.
- Miscellaneous:
-
- Sera from patients with systemic lupus erythematosus (SLE) often contain antibodies that react with the normal cellular La protein as if this antigen was foreign.
Protein Expression for SSB Gene
Post-translational modifications for SSB Gene
- Phosphorylated. The phosphorylation sites are at the C-terminal part of the protein.
- The N-terminus is blocked.
- Ubiquitination at posLast=99, posLast=7676, Lys95, Lys116, Lys176, isoforms=224, Lys229, isoforms=287, isoforms=312, and posLast=328328
- Modification sites at PhosphoSitePlus
Other Protein References for SSB Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Cell Signaling Technology (CST) Antibodies for SSB (SSB)
- Novus Biologicals Antibodies for SSB
- Invitrogen Antibodies for SSB
- GeneTex SSB antibody for SSB
-
Santa Cruz Biotechnology (SCBT) Antibodies for SSB
Protein Products
-
OriGene Purified Proteins for SSB
- Search Origene for MassSpec and Protein Over-expression Lysates for SSB
- Origene Custom Protein Services for SSB
- Search GeneTex for Proteins for SSB
Assay Products
-
Custom Assay ServicesOriGene ELISA Kits for SSB
No data available for DME Specific Peptides for SSB Gene
Domains & Families for SSB Gene
Gene Families for SSB Gene
Protein Domains for SSB Gene
Suggested Antigen Peptide Sequences for SSB Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for SSB Gene
Function for SSB Gene
Molecular function for SSB Gene
- UniProtKB/Swiss-Prot Function:
- Binds to the 3 poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation (PubMed:3192525, PubMed:2470590). In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:12384597).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000049 | tRNA binding | IMP | 10983981 |
| GO:0000166 | nucleotide binding | IEA | -- |
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0003723 | RNA binding | IDA,IMP | 3192525 |
| GO:0003729 | mRNA binding | TAS | 9154801 |
Phenotypes for SSB Gene
- MGI mutant phenotypes for SSB:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for SSB:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for SSB
-
-
ViGene Biosciences lentiviral particle packaged cDNA for SSB gene
-
ViGene Biosciences ready-to-package AAV shRNAs for SSB gene
- Search ViGene Biosciences for SSB
CRISPR Products
-
OriGene CRISPR knockouts for SSB
-
Santa Cruz Biotechnology (SCBT) CRISPR for SSB
- GenScript: Design CRISPR guide RNA sequences for SSB
miRNA for SSB Gene
- miRTarBase miRNAs that target SSB
miRNA Products
- Search ViGene Biosciences for SSB
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for SSB
- Browse OriGene Inhibitory RNA Products For SSB
-
ViGene Biosciences ready-to-package AAV shRNAs for SSB gene
Clone Products
- Sino Biological Human cDNA Clone for SSB
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for SSB
- VectorBuilder custom plasmid, inducible vectors for SSB
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SSB
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for SSB gene
-
ViGene Biosciences lentiviral particle packaged cDNA for SSB gene
-
ViGene Biosciences ready-to-package AAV shRNAs for SSB gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SSB Gene
Localization for SSB Gene
Subcellular locations from UniProtKB/Swiss-Prot for SSB Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000784 | nuclear chromosome, telomeric region | IDA | 19135898 |
| GO:0005634 | nucleus | IDA | 17308035 |
| GO:0005737 | cytoplasm | IDA | 17308035 |
| GO:0030529 | intracellular ribonucleoprotein complex | IEA,TAS | -- |
Pathways & Interactions for SSB Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | RNA Polymerase III Transcription Initiation | ||
| 2 | Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | ||
| 3 | Translational Control | ||
| 4 | Gene Expression |
.48
|
|
Pathways by source for SSB Gene
1 Cell Signaling Technology pathway for SSB Gene
1 KEGG pathway for SSB Gene
Interacting Proteins for SSB Gene
Selected Interacting proteins:
P05455-LA_HUMAN
ENSP00000260956
for SSB Gene via
MINT
STRING
UniProtKB
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001682 | tRNA 5-leader removal | IGI | 10983981 |
| GO:0006396 | RNA processing | IEA | -- |
| GO:0006400 | tRNA modification | TAS | 10983981 |
| GO:0006409 | tRNA export from nucleus | IMP | 17308035 |
| GO:0008033 | tRNA processing | IMP | 17308035 |
Transcripts for SSB Gene
mRNA/cDNA for SSB Gene
- (2) REFSEQ mRNAs :
- (13) Additional mRNA sequences :
- (308) Selected AceView cDNA sequences:
- (12) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for SSB Gene
CRISPR Products
-
OriGene CRISPR knockouts for SSB
-
Santa Cruz Biotechnology (SCBT) CRISPR for SSB
- GenScript: Design CRISPR guide RNA sequences for SSB
miRNA Products
- Search ViGene Biosciences for SSB
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for SSB
- Browse OriGene Inhibitory RNA Products For SSB
-
ViGene Biosciences ready-to-package AAV shRNAs for SSB gene
Clone Products
- Sino Biological Human cDNA Clone for SSB
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for SSB
- VectorBuilder custom plasmid, inducible vectors for SSB
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SSB
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for SSB Gene
This gene is overexpressed in Peripheral blood mononuclear cells (6.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for SSB Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of SSB Gene:
SSBSOURCE GeneReport for Unigene cluster for SSB Gene:
Hs.632535Evidence on tissue expression from TISSUES for SSB Gene
- Liver(4.5)
- Muscle(4.5)
- Nervous system(3.9)
- Heart(2.7)
- Spleen(2.5)
- Kidney(2.4)
- Blood(2.3)
- Eye(2.3)
- Skin(2.3)
- Lung(2.2)
Primer Products
-
OriGene qPCR primer pairs and template standards for SSB
-
OriGene qPCR primer pairs for SSB
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for SSB Gene
Orthologs for SSB Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | SSB 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | SSB 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | SSB 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Ssb 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Ssb 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | SSB 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
OneToMany | |
| -- 35 |
|
OneToMany | |||
| -- 35 |
|
OneToMany | |||
| chicken (Gallus gallus) |
Aves | SSB 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | SSB 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | ssb 34 |
|
||
| Str.2099 34 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | MGC52876 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | ssb 34 35 |
|
||
| wufb17f11 34 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | La 36 34 35 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP008952 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | C44E4.4 36 34 35 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | LHP1 35 37 |
|
OneToMany |
- Species where no ortholog for SSB was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for SSB Gene
(3) SIMAP similar genes for SSB Gene using alignment to 5 proteins:
Pseudogenes.org Pseudogenes for SSB Gene
No data available for Paralogs for SSB Gene
Variants for SSB Gene
| SNP ID | Clin | Chr 02 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000062870 | -- | 169,812,221(+) | AATAA(C/T)TACTT | intron-variant, downstream-variant-500B | |
| rs1000367676 | -- | 169,805,228(+) | CATAT(A/G)ATCTT | intron-variant | |
| rs1000399055 | -- | 169,812,515(+) | TAAAA(C/T)AAAAG | intron-variant, downstream-variant-500B | |
| rs1000745872 | -- | 169,809,125(+) | CCTGT(A/G)ATCCC | intron-variant | |
| rs1000749513 | -- | 169,801,955(+) | TGCAG(A/G)AGGAT | intron-variant |
Residual Variation Intolerance Score:
34.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.69;
32.20% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for SSB Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SSB
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SSB Gene
Disorders for SSB Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| sjogren's syndrome |
|
|
| lupus erythematosus |
|
|
| systemic lupus erythematosus |
|
|
| undifferentiated connective tissue disease |
|
|
| hepatitis c virus |
|
|
Search SSB in MalaCards
View complete list of genes associated with diseases
Relevant External Links for SSB
No data available for UniProtKB/Swiss-Prot and Genatlas for SSB Gene
Publications for SSB Gene
- Fine epitope mapping of the human SS-B/La protein. Identification of a distinct autoepitope homologous to a viral gag polyprotein. (PMID: 1692037) Kohsaka H. … Miyamoto T. (J. Clin. Invest. 1990) 2 3 22 64
- Ribonucleoprotein SS-B/La belongs to a protein family with consensus sequences for RNA-binding. (PMID: 2468131) Chan E.K.L. … Tan E.M. (Nucleic Acids Res. 1989) 2 3 4 64
- Structural analysis reveals conformational plasticity in the recognition of RNA 3' ends by the human La protein. (PMID: 18547518) Kotik-Kogan O. … Curry S. (Structure 2008) 3 4 64
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4 64
- Structural basis for recognition and sequestration of UUU(OH) 3' termini of nascent RNA polymerase III transcripts by La, a rheumatic disease autoantigen. (PMID: 16387655) Teplova M. … Patel D.J. (Mol. Cell 2006) 3 4 64
Products for SSB Gene
- Browse R&D Systems for Antibodies
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- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
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- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for SSB
- Custom Assay ServicesOriGene ELISA Kits for SSB
- OriGene Purified Proteins for SSB
- Search Origene for MassSpec and Protein Over-expression Lysates for SSB
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- OriGene qPCR primer pairs and template standards for SSB
- OriGene qPCR primer pairs for SSB
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- GenScript: Next-day shipping cDNA ORF clone for SSB in any vector
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- GenScript: Design CRISPR guide RNA sequences for SSB
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- CloneReady with Over 120,000 Genes
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- Cell Signaling Technology (CST) Antibodies for SSB (SSB)
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for SSB
- Novus Biologicals proteins and lysates for SSB
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ViGene Biosciences adenoviral particle packaged cDNA for SSB gene
- ViGene Biosciences lentiviral particle packaged cDNA for SSB gene
- ViGene Biosciences ready-to-package AAV shRNAs for SSB gene
- Search ViGene Biosciences for SSB
- Santa Cruz Biotechnology (SCBT) Antibodies for SSB
- Search Santa Cruz Biotechnology (SCBT) for SSB siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for SSB
- Cyagen custom Knockout/knockin (KOKI) mouse models for SSB
- VectorBuilder custom plasmid, inducible vectors for SSB
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SSB
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for SSB Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer