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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SS18L1 Gene

protein-coding   GIFtS: 52
GCID: GC20P060718

synovial sarcoma translocation gene on chromosome 18-like...

 Explore 4 diseases affiliated with
SS18L1 via our new
 Human Malady Compendium 
Biological research products
for SS18L1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Synovial Sarcoma Translocation Gene On Chromosome 18-Like 11 2     SYT Homolog 12 3
KIAA06931 3 5     LP22612
CREST2 3 5     Calcium-Responsive Transactivator2
SS18-Like Protein 12 3     

External Ids:    HGNC: 155921   Entrez Gene: 260392   Ensembl: ENSG000001844027   OMIM: 6064725   UniProtKB: O751773   

Export aliases for SS18L1 gene to outside databases

Previous GC identifers: GC20P060482 GC20P061357 GC20P061404 GC20P060152 GC20P057510


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SS18L1:
Synovial sarcomas occur most frequently in the extremities around large joints. More than 90% of cases have a recurrent
and specific chromosomal translocation, t(X;18)(p11.2;q11.2), in which the 5-prime end of the SS18 gene (MIM 600192)
is fused in-frame to the 3-prime end of the SSX1 (MIM 312820), SSX2 (MIM 300192), or SSX4 (MIM 300326) gene. The
SS18L1 gene is homologous to SS18.(supplied by OMIM, Jul 2002)

UniProtKB/Swiss-Prot: CREST_HUMAN, O75177
Function: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical
neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein
complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a
recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by
BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by
calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of
CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1
complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of
HDAC1 and recruitment of CREBBP (By similarity)

Gene Wiki entry for SS18L1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NC_018931.1  NT_011362.10  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SS18L1 gene promoter:
         AP-2alpha isoform 3   AP-2alpha isoform 2   AP-2alpha   AP-2alphaA   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for SS18L1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SS18L1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.3   Ensembl cytogenetic band:  20q13.33   HGNC cytogenetic band: 20q13.3

SS18L1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SS18L1 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P060718:  view genomic region     (about GC identifiers)

Start:
60,718,822 bp from pter      End:
60,757,566 bp from pter
Size:
38,745 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CREST_HUMAN, O75177 (See protein sequence)
Recommended Name: Calcium-responsive transactivator  
Size: 396 amino acids; 42990 Da
Subunit: Homodimer. Dimerization may be necessary for its function in neuronal dendritic development. Interacts (via
C-terminus) with CREBBP (via N-terminus), EP300 and SMARCA4/BRG1. Interacts with the nBAF complex. Association with
CREBBP facilitates transcription while the association with SMARCA4/BRG1 suppresses CREST-mediated transcription in
resting neurons (By similarity)
Subcellular location: Nucleus (By similarity). Chromosome, centromere, kinetochore (By similarity). Note=Localizes to
nuclear bodies. Co-localizes with SGOL1 at kinetochore (By similarity)
Sequence caution: Sequence=BAA31668.1; Type=Erroneous initiation;
Secondary accessions: A6NNE3 A8K620 B3KWR8 E1P5H7 Q5JXJ3 Q6MZV9 Q6NTH3 Q6XYD9 Q8NE69 Q9BR55 Q9H4K6
Alternative splicing: 5 isoforms:  O75177-1   O75177-2   O75177-3   O75177-4   O75177-5   

Explore the universe of human proteins at neXtProt for SS18L1: NX_O75177

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O75177

  • SS18L1 Protein expression data from MOPED and PaxDb:    About this image 
    SS18L1 Protein Expression
    REFSEQ proteins: NP_945173.1  
    ENSEMBL proteins: 
     ENSP00000333012   ENSP00000398634   ENSP00000434451   ENSP00000393999   ENSP00000359885  

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    Uscn Proteins for SS18L1

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000777condensed chromosome kinetochore IEA--
    GO:0000780condensed nuclear chromosome, centromeric region IEA--
    GO:0005634nucleus ISS--
    GO:0016604nuclear body IEA--

    SS18L1 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    SS18L1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR007726 SSXT

    Graphical View of Domain Structure for InterPro Entry O75177

    ProtoNet protein and cluster: O75177

    2 Blocks protein families:
    IPB000532 Glucagon/GIP/secretin/VIP
    IPB007726 SSXT


    UniProtKB/Swiss-Prot: CREST_HUMAN, O75177
    Domain: The MFD (multi-functional domain) domain is involved in transcription transactivation, nuclear body targeting
    and dimerization (By similarity)
    Similarity: Belongs to the SS18 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CREST_HUMAN, O75177
    Function: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical
    neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein
    complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a
    recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by
    BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by
    calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of
    CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1
    complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of
    HDAC1 and recruitment of CREBBP (By similarity)

    Phenotypes:
         1 GenomeRNAi human phenotype for SS18L1:

     Decreased Wnt reporter activit 

         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ss18l1):
     behavior/neurological  growth/size  mortality/aging  nervous system  reproductive system 

    SS18L1 for phenotypes           About GeneDecksing

    Animal Models:
         Mouse knock-out Ss18l1tm1Ghsh for SS18L1
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for SS18L1 

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    hsa-miR-520e hsa-miR-520f hsa-miR-3938 hsa-miR-106a hsa-miR-128 hsa-miR-938 hsa-miR-10b* hsa-miR-93
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SS18L1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SS18L1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/30 Interacting proteins for SS18L1 (O751773 ENSP000003330124) via UniProtKB, MINT, STRING, and/or I2D (see all 30)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMARCA4P515323, ENSP000003507204I2D: score=2 STRING: ENSP00000350720
    AATFQ9NY613, ENSP000002254024I2D: score=1 STRING: ENSP00000225402
    ELF5Q9UKW63, ENSP000003110104I2D: score=1 STRING: ENSP00000311010
    HDAC4P565243, ENSP000002646064I2D: score=1 STRING: ENSP00000264606
    MED30Q96HR33, ENSP000002973474I2D: score=1 STRING: ENSP00000297347
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0016358dendrite development IEA--
    GO:0016568chromatin modification IEA--
    GO:0045893positive regulation of transcription, DNA-dependent ISS--
    GO:0050773regulation of dendrite development IEA--

    SS18L1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SS18L1
    Search CenterWatch for drugs/clinical trials and news about SS18L1 / CREST 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SS18L1 gene (2 alternative transcripts): 
    NM_015558.3  NM_198935.1  

    Unigene Cluster for SS18L1:

    Synovial sarcoma translocation gene on chromosome 18-like 1
    Hs.154429  [show with all ESTs]
    Unigene Representative Sequence: NM_198935
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000331758(uc002ycb.3) ENST00000450482 ENST00000491916 ENST00000492466
    ENST00000421564(uc011aaa.1 uc002ybz.1 uc002yca.1) ENST00000370848(uc002ycc.1)


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    hsa-miR-520e hsa-miR-520f hsa-miR-3938 hsa-miR-106a hsa-miR-128 hsa-miR-938 hsa-miR-10b* hsa-miR-93
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    Additional cDNA sequence: 

    AB014593.1 AK125656.1 AK291485.1 AK299881.1 AK308765.1 

    7 DOTS entries:

    DT.100639850  DT.102836174  DT.91997047  DT.101981474  DT.91650539  DT.120813157  DT.120813153 

    24/73 AceView cDNA sequences (see all 73):

    AA488223 AW952446 BC034494 H01063 BU676187 BM452970 T52987 BU176753 
    AB014593 AA488199 AY203931 NM_198935 NM_015558 BC068993 BX483299 AW152517 
    BQ025990 AA488169 BG150091 BQ722557 BE221720 AI206618 BX501113 AA345510 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for SS18L1 (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9 ^ 10 ^ 11
    SP1:              -     -           -           -                                                               
    SP2:                                                                                                            
    SP3:                    -           -           -                                                               
    SP4:              -                 -           -                                                               
    SP5:                    -                                                                                       


    ECgene alternative splicing isoforms for SS18L1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SS18L1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --
    SS18L1 Expression
    About this image
    See SS18L1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SS18L1

    SOURCE GeneReport for Unigene cluster: Hs.154429

    UniProtKB/Swiss-Prot: CREST_HUMAN, O75177
    Tissue specificity: Ubiquitous; with lowest levels in spleen

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SS18L1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SS18L1 gene from 5/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ss18l11 , 5 synovial sarcoma translocation gene on chromosome 18-like more1, 5 88.22(n)1
    91.16(a)1
      2 (102.56 cM)5
    2693971  NM_178750.51  NP_848865.41 
     1800425095 
    chicken
    (Gallus gallus)
    Aves SS18L11 synovial sarcoma translocation gene on chromosome 18-like more 77.02(n)
    87.37(a)
      419225  XM_417402.3  XP_417402.3 
    lizard
    (Anolis carolinensis)
    Reptilia SS18L16
    --
    83(a)
    1 ↔ 1
    4(150639597-150668520)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AN36
    GIF36
    (see all 3)
    GRF1-interacting factor 3
    (see all 3)
    23(a)
    20(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    5(10647570-10649892)
    4(357551-359194)
    rice
    (Oryza sativa)
    Liliopsida --
    --
    (see all 3)
    GRF-interacting factor 2, putative, expressed
    (see all 3)
    24(a)
    23(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    12(18827072-18832082)
    11(23447472-23451072)


    ENSEMBL Gene Tree for SS18L1 (if available)
    TreeFam Gene Tree for SS18L1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SS18L1 gene
    SS182  SS18L22  
    5 SIMAP similar genes for SS18L1 using alignment to 3 protein entries:     CREST_HUMAN (see all proteins):
    SS18L2    SYT    SS18    SYT-SSX1    SYT-SSX2

    SS18L1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SS18L1
    PGOHUM00000248341


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/983 NCBI SNPs in SS18L1 are shown (see all 983    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1879586721,2
    --60720526(+) ACCCAG/TAGCAT 1 -- int10--------
    rs1912003651,2
    --60720619(+) CACTTC/TGCACA 1 -- int10--------
    rs37612231,2
    C,F,A--60720646(+) CCCCAA/GATTCT 1 -- int112Minor allele frequency- N:0.01EA NA WA 576
    rs37612241,2
    C,F--60720668(+) TGTGTA/GTTGAG 1 -- int12Minor allele frequency- G:0.07WA EA 238
    rs37612251,2
    C,F,A--60720682(+) CTGCCG/CCGAAC 1 -- int18Minor allele frequency- C:0.41NA WA EA 368
    rs1478648451,2
    --60720815(+) GTCTGC/TGTATT 1 -- int10--------
    rs1398929691,2
    --60720830(+) TTGGTA/GTTTTG 1 -- int10--------
    rs1156072621,2
    --60720848(+) ATATAT/CGTACC 1 -- int11Minor allele frequency- C:0.01WA 118
    rs72715051,2
    C,F,H--60720964(+) ATGCCG/AAGAGC 1 -- int18Minor allele frequency- A:0.01NS EA NA WA 822
    rs1825260831,2
    --60721036(+) AACTTA/GTCCTT 1 -- int10--------

    HapMap Linkage Disequilibrium report for SS18L1 (60718822 - 60757566 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for SS18L1
         1 CNV: 73562

    SABiosciences Cancer Mutation PCR Assays
    1 SABiosciences qBiomarker Copy Number PCR Array containing SS18L1:
    Ovarian Cancer
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SS18L1
    DNA2.0 Custom Variant and Variant Library Synthesis for SS18L1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    SS18L1 for disorders           About GeneDecksing

    OMIM gene information: 606472    OMIM disorders: --

    4 diseases for SS18L1:    About MalaCards
    synovial sarcoma    sarcoma    kidney disease    neuronitis

    1 disease from the University of Copenhagen DISEASES database for SS18L1:
    Synovial sarcoma
    Human Genome Epidemiology (HuGE) Navigator: SS18L1 (3 documents)

    Export disorders for SS18L1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SS18L1 gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with SS18L1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    3. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)1, 2 Ishikawa K.... Ohara O. (1998)
    4. Common origin of the human synovial sarcoma associated SS18 and SS18L1 gene loci. (PubMed id 16484776)1, 9 de Bruijn D.R. and Geurts van Kessel A. (2006)
    5. A novel fusion gene, SS18L1/SSX1, in synovial sarcoma. (PubMed id 12696068)1, 9 Storlazzi C.T....Panagopoulos I. (2003)
    6. Mapping and characterization of the mouse and human SS18 genes, two human SS18-like genes and a mouse Ss18 pseudogene. (PubMed id 11435705)1, 9 de Bruijn D.R....Geurts Van Kessel A. (2001)
    7. Aurora B controls kinetochore-microtubule attachments by inhibiting Ska complex-KMN network interaction. (PubMed id 22371557)1 Chan Y.W....Santamaria A. (2012)
    8. The Brd4 extraterminal domain confers transcription a ctivation independent of pTEFb by recruiting multiple proteins, including NSD3. (PubMed id 21555454)1 Rahman S....Howley P.M. (2011)
    9. Assessment of a polymorphism of SDK1 with hypertensio n in Japanese Individuals. (PubMed id 19851296)1 Oguri M....Yamada Y. (2010)
    10. An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26039 HGNC: 15592 AceView: SS18L1 Ensembl:ENSG00000184402 euGenes: HUgn26039
    ECgene: SS18L1 H-InvDB: SS18L1

    (According to HUGE)
    About This Section
    HUGE: KIAA0693

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SS18L1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for SS18L1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SS18L1 gene:
    Search GeneIP for patents involving SS18L1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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