SS18 Gene
protein-coding GIFtS: 51
GCID: GC18M023596
|
|
synovial sarcoma translocation, chromosome 18 (Previous symbol: SSXT)
| |
Aliases for SS18 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Synovial Sarcoma Translocation, Chromosome 181 2 | | Protein SSXT2 | | SSXT1 2 3 5 | | Synovial Sarcoma, Translocated To X Chromosome2 | | SYT1 2 3 5 | | Protein SYT3 | | Synovial Sarcoma Translocated To X Chromosome Protein2 3 | | |
Export aliases for SS18 gene to outside databasesPrevious GC identifers: GC18M023570 GC18M023308 GC18M021848 GC18M021850 GC18M020454 |
Summaries for SS18 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: SSXT_HUMAN, Q15532Function: Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation Gene Wiki entry for SS18
|
Genomic Views for SS18 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000018.9 NC_018929.1 NT_010966.14
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the SS18 gene promoter: C/EBPbeta AML1a Sp1 FOXJ2 (long isoform) HNF-1 FOXJ2 HNF-1A Other transcription factors
Search SABiosciences Chromatin IP Primers for SS18
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SS18 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 18q11.2 Ensembl cytogenetic band: 18q11.2 HGNC cytogenetic band: 18q11.2SS18 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 18 GeneLoc Exon Structure GeneLoc location for GC18M023596: view genomic region
(about GC identifiers)
Start:
|
23,596,217 bp from pter |
End:
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23,671,181 bp from pter |
Size:
|
74,965 bases |
Orientation:
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minus strand |
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Proteins for SS18 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: SSXT_HUMAN, Q15532 (See
protein sequence)Recommended Name: Protein SSXT Size: 418 amino acids; 45929 Da
Subunit: Interacts with MLLT10. Isoform 1 interacts with RBM14 isoform 1. Isoform 2 interacts with RBM14 isoform 1
Subcellular location: Nucleus (Probable)
Sequence caution: Sequence=AAK21314.1; Type=Erroneous initiation; Sequence=CAA55792.1; Type=Erroneous initiation;
Secondary accessions: B0YJ95 Q16404 Q4VAX1 Q9BXC6Alternative splicing: 2 isoforms: Q15532-1 Q15532-2 Explore the universe of human proteins at neXtProt for SS18: NX_Q15532
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q15532 SS18 Protein expression data from MOPED and PaxDb: About this image 
 REFSEQ proteins (2 alternative transcripts):
NP_001007560.1 NP_005628.2 ENSEMBL proteins: ENSP00000414516 ENSP00000438066 ENSP00000462363 ENSP00000269138 ENSP00000269137 ENSP00000462838 ENSP00000441760 ENSP00000464664 ENSP00000462766 ENSP00000463933 ENSP00000463943 ENSP00000464673 ENSP00000463928 ENSP00000463586 ENSP00000463802 ENSP00000464609 ENSP00000464556 ENSP00000464049 ENSP00000462104 ENSP00000444551 ENSP00000443097 ENSP00000444647 Human Recombinant Protein Products for SS18:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- | | GO:0005881 | cytoplasmic microtubule |
IEA | -- |
SS18 for ontologies About GeneDecksing
SS18 Antibody Products: Assay Products for SS18: |
Protein
Domains / Families for SS18 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SS18 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q15532ProtoNet protein and cluster: Q15532 1 Blocks protein family: IPB007726 SSXT
UniProtKB/Swiss-Prot: SSXT_HUMAN, Q15532Similarity: Belongs to the SS18 family |
Function for SS18 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: UniProtKB/Swiss-Prot Summary: SSXT_HUMAN, Q15532Function: Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
IPI | -- | | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity |
IDA | 15919756 |
SS18 for ontologies About GeneDecksing
Phenotypes: 6 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Ss18):
SS18 for phenotypes About GeneDecksing
Animal Models: Mouse knock-out Ss18tm1Adg for SS18
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SS18 (see all 8) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SS18 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): SS18 (NM_001007559) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SS18 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SS18  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SS18 |
|
Pathways & Interactions for SS18 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SS18
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/61 Interacting proteins for SS18 (Q155321, 3 ENSP000002691384) via UniProtKB, MINT, STRING, and/or I2D (see all 61)About this table
Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000226 | microtubule cytoskeleton organization |
IEA | -- | | GO:0000902 | cell morphogenesis |
IEA | -- | | GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0007010 | cytoskeleton organization |
-- | -- | | GO:0007243 | intracellular protein kinase cascade |
IEA | -- |
SS18 for ontologies About GeneDecksing
|
Drugs & Compounds for SS18 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SS18 for compounds About GeneDecksing
Browse Tocris compounds for SS18 3 Novoseek chemical compound relationships for SS18 gene About this table
Search CenterWatch for drugs/clinical trials and news about SS18 / SSXT 
|
Transcripts for SS18 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for SS18 gene (2 alternative transcripts): NM_001007559.1 NM_005637.2 Unigene Cluster for SS18: Synovial sarcoma translocation, chromosome 18 Hs.129261 [show with all ESTs]Unigene Representative Sequence: NM_00100755918/29 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 29): ENST00000415083(uc002kvm.3 uc002kvn.3 uc010xbf.2 uc010xbg.2 uc010xbh.2 uc010xbi.2 uc010dlz.1) ENST00000542420 ENST00000579640 ENST00000269138 ENST00000269137 ENST00000585121 ENST00000580958 ENST00000582092 ENST00000539244 ENST00000585241 ENST00000578954 ENST00000579061 ENST00000577636 ENST00000584083 ENST00000578700 ENST00000582792 ENST00000581021 ENST00000577572
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SS18 (see all 8) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SS18 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): SS18 (NM_001007559) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SS18 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SS18  |
Additional cDNA sequence: AF244972.1 AF343880.1 AF402618.1 AK289510.1 AK296949.1 AK299082.1 AK301504.1 AK304305.1 AK307923.1 AK316302.1 AK316338.1 BC096221.1 BC096222.1 BC096223.1 BC096224.1 CR542088.1 CR542103.1 X79201.1 20 DOTS entries: DT.113857 DT.121097311 DT.100745105 DT.105718 DT.121097290 DT.100798265 DT.121097277 DT.75145663 DT.95276193 DT.100714045 DT.100798264 DT.101962724 DT.121097281 DT.121097284 DT.121097299 DT.121097302 DT.97843921 DT.100798261 DT.75107159 DT.91657720 24/248 AceView cDNA sequences (see all 248): CK823193 BX645814 AA375833 BX486685 BU521546 BF330745 CB068575 BM992802 BQ100914 AL599336 BP360387 CF529036 AI458444 BU687887 CA442904 AA376490 CB148207 BM472976 BX327397 BE301610 BP364367 AA715136 N59206 BM475931 GeneLoc Exon Structure
5/14 Alternative Splicing Database (ASD) splice patterns (SP) for SS18 (see all 14) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | · | 11c | · | 11d | · | 11e | ^ | 12a | · | 12b | ^ | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | |   | - |   | - |   | - |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | |   | - |   | - |   | - |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | |   | - |   | - |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | |   | - |   | |   | - |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | - |   | - |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16a | · | 16b | ^ | 17 | |
| SP1: | |   | |   | - |   | |   | |   | |   | |   | |
| SP2: | |   | - |   | - |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for SS18
|
Expression for SS18 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SS18 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: GACAGCCTTA
 About this image See SS18 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for SS18
SOURCE GeneReport for Unigene cluster: Hs.129261
UniProtKB/Swiss-Prot: SSXT_HUMAN, Q15532Tissue specificity: Fairly ubiquitously expressed. Expressed in synovial sarcomas and in other human cell lines. Thefusion genes SSXT-SSX1 and SSXT-SSX2 are expressed only in synovial sarcomas SABiosciences Custom PCR Arrays for SS18
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SS18 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SS18 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SS18 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SS18 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SS18 |
Orthologs for SS18 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SS18 gene from 6/18 species (see all 18) About this table
ENSEMBL Gene Tree for SS18 (if available) TreeFam Gene Tree for SS18 (if available)  |
Paralogs for SS18 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for SS18 gene
- SS18L12 SS18L22
10 SIMAP similar genes for SS18 using alignment to 19 protein entries: SSXT_HUMAN (see all proteins):SYT SYT-SSX1 SYT-SSX2 TARDBP FLJ10385 unknown SS18L2 SS18L1 HSH2D NARF
SS18 for paralogs About GeneDecksing
|
Genomic Variants for SS18 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 18 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for SS18 (23596217 - 23671181 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for SS18: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SS18 |
|
Disorders
/ Diseases for SS18 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SS18 for disorders About GeneDecksing
OMIM gene information: 600192
OMIM disorders: --
UniProtKB/Swiss-Prot: SSXT_HUMAN, Q15532
Note=A chromosomal aberration involving SS18 may be a cause of synovial sarcoma. Translocationt(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusionproducts SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position ofthe breakpoint can occur (low frequency) 14 diseases for SS18: About MalaCardssynovial sarcoma sarcoma colorado tick fever peroneal nerve paralysis monophasic synovial sarcoma biphasic synovial sarcoma spindle cell synovial sarcoma primitive neuroectodermal tumor neuroectodermal tumors epithelioid sarcoma paralysis acute leukemia leukemia melanoma 3 diseases from the University of Copenhagen DISEASES database for SS18:Synovial sarcoma Colorado tick fever Sarcoma 5 Novoseek disease relationships for SS18 gene About this table
Export disorders for SS18 gene to outside databases
|
Publications for SS18 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SS18 gene, integrated from 9 sources (see all 99): (articles sorted by number of sources associating them with SS18) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma. (PubMed id 7951320)1, 2, 3, 9 Clark J.... Cooper C.S. (1994)
- Cloning and characterization of spliced fusion transcript variants of synovial sarcoma: SYT/SSX4, SYT/SSX4v, and SYT/SSX2v. Possible regulatory role of the fusion gene product in wild type SYT expression. (PubMed id 11368913)1, 2, 9 Brodin B.... Larsson O. (2001)
- The synovial sarcoma associated protein SYT interacts with the acute leukemia associated protein AF10. (PubMed id 11423977)1, 2, 9 de Bruijn D.R....Geurts van Kessel A. (2001)
- Common origin of the human synovial sarcoma associated SS18 and SS18L1 gene loci. (PubMed id 16484776)1, 3, 9 de Bruijn D.R. and Geurts van Kessel A. (2006)
- Molecular diagnosis of synovial sarcoma and characterization of a variant SYT-SSX2 fusion transcript. (PubMed id 7495284)1, 2, 9 Fligman I....Ladanyi M. (1995)
- Synovial sarcoma translocation (SYT) encodes a nuclear receptor coactivator. (PubMed id 15919756)1, 2 Iwasaki T.... Chin W.W. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The t(X;18)(p11.2;q11.2) translocation found in human synovial sarcomas involves two distinct loci on the X chromosome. (PubMed id 8152806)1, 3 Shipley J.M....Gusterson B.A. (1994)
- Functional domains of the SYT and SYT-SSX synovial sarcoma translocation proteins and co-localization with the SNF protein BRM in the nucleus. (PubMed id 10072425)1, 9 Thaete C....Goodwin G. (1999)
- Cytosolic SYT/SS18 isoforms are actin-associated prot eins that function in matrix-specific adhesion. (PubMed id 19649286)1, 9 Kim J....Parks W.C. (2009)
|
External Searches for SS18 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing SS18 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SS18 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SS18 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
|
About This Section
| Patent Information for SS18 gene: Search GeneIP for patents involving SS18
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for SS18 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for SS18 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SS18 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SS18 | | OriGene Protein Over-expression Lysate for SS18 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for SS18 | | OriGene 3'-UTR Clone for SS18 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SS18 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SS18 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for SS18 | | OriGene Custom Protein Services for SS18 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SS18 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SS18 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SS18 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SS18 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SS18 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SS18 |
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| | | Search Tocris compounds for SS18 |
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 | | SS18 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SS18 |
|  |  |  |  | | | Search ThermoFisher Antibodies for SS18 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SS18 |
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