Aliases for SRXN1 Gene
External Ids for SRXN1 Gene
Previous HGNC Symbols for SRXN1 Gene
Previous GeneCards Identifiers for SRXN1 Gene
GeneCards Summary for SRXN1 Gene
SRXN1 (Sulfiredoxin 1) is a Protein Coding gene. Among its related pathways are Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling. GO annotations related to this gene include oxidoreductase activity, acting on a sulfur group of donors and sulfiredoxin activity.
UniProtKB/Swiss-Prot for SRXN1 Gene
Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase.