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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SRSF9 Gene

protein-coding   GIFtS: 59
GCID: GC12M120900

Serine/Arginine-Rich Splicing Factor 9

(Previous names: splicing factor, arginine/serine-rich 9)
(Previous symbol: SFRS9)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Serine/Arginine-Rich Splicing Factor 91 2     Pre-MRNA-Splicing Factor SRp30C2 3
Splicing Factor, Arginine/Serine-Rich 91 2 3     SRp30c2
SFRS91 2 3     SRP30C3
SR Splicing Factor 91 2     

External Ids:    HGNC: 107911   Entrez Gene: 86832   Ensembl: ENSG000001117867   OMIM: 6019435   UniProtKB: Q132423   

Export aliases for SRSF9 gene to outside databases

Previous GC identifer: GC12M117908


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SRSF9 Gene:
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors,
which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for
binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues
and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA
splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation.
Two pseudogenes, one on chromosome 15 and the other on chromosome 21, have been found for this gene. (provided by
RefSeq, Sep 2010)

GeneCards Summary for SRSF9 Gene: 
SRSF9 (serine/arginine-rich splicing factor 9) is a protein-coding gene. Diseases associated with SRSF9 include distal hereditary motor neuropathy, and primary open angle glaucoma, and among its related super-pathways are mRNA Processing and Post-Elongation Processing of Intron-Containing pre-mRNA. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is SRSF5.

UniProtKB/Swiss-Prot: SRSF9_HUMAN, Q13242
Function: Plays a role in constitutive splicing and can modulate the selection of alternative splice sites.
Represses the splicing of MAPT/Tau exon 10

Gene Wiki entry for SRSF9 (SFRS9) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.2  NT_009775.17  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for SRSF9
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSRSF9 promoter sequence
   Search SABiosciences Chromatin IP Primers for SRSF9

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SRSF9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24.31   Ensembl cytogenetic band:  12q24.31   HGNC cytogenetic band: 12q24.31

SRSF9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SRSF9 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M120900:  view genomic region     (about GC identifiers)

Start:
120,899,471 bp from pter      End:
120,907,596 bp from pter
Size:
8,126 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SRSF9_HUMAN, Q13242 (See protein sequence)
Recommended Name: Serine/arginine-rich splicing factor 9  
Size: 221 amino acids; 25542 Da
Subunit: Interacts with KHDRBS3 (By similarity). Interacts with NOL3/ARC/NOP30, NSEP1/YB-1/YB1, SAFB/SAFB1,
SRSF6/SFRS6, TRA2B/SFRS10 and C1QBP. May also interact with DUSP11/PIR1
Subcellular location: Nucleus. Note=Cellular stresses such as heat shock may induce localization to discrete
nuclear bodies termed SAM68 nuclear bodies (SNBs), HAP bodies, or stress bodies. Numerous splicing factors
including SRSF1/SFRS1/SF2, SRSF7/SFRS7, SAFB and KHDRBS1/SAM68 accumulate at these structures, which may
participate in the post-transcriptional regulation of mRNAs in stressed cells
Secondary accessions: Q52LD1

Explore the universe of human proteins at neXtProt for SRSF9: NX_Q13242

Explore proteomics data for SRSF9 at MOPED 

Post-translational modifications:

  • UniProtKB: Extensively phosphorylated on serine residues in the RS domain (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q13242

  • SRSF9 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SRSF9 Protein Expression
    REFSEQ proteins: NP_003760.1  
    ENSEMBL proteins: 
     ENSP00000229390   ENSP00000474283   ENSP00000449030  
    Reactome Protein details: Q13242
    Human Recombinant Protein Products for SRSF9: 
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    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005654nucleoplasm TAS--
    GO:0005730NOT nucleolus IDA--

    SRSF9 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    RBM: RNA binding motif (RRM) containing
    SRSF: Serine/arginine-rich splicing factors

    2 InterPro protein domains:
     IPR000504 RRM_dom
     IPR012677 Nucleotide-bd_a/b_plait

    Graphical View of Domain Structure for InterPro Entry Q13242

    ProtoNet protein and cluster: Q13242

    1 Blocks protein domain: IPB000504 RNA-binding region RNP-1 (RNA recognition motif)

    UniProtKB/Swiss-Prot: SRSF9_HUMAN, Q13242
    Similarity: Belongs to the splicing factor SR family
    Similarity: Contains 2 RRM (RNA recognition motif) domains


    SRSF9 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SRSF9_HUMAN, Q13242
    Function: Plays a role in constitutive splicing and can modulate the selection of alternative splice sites.
    Represses the splicing of MAPT/Tau exon 10

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding IEA--
    GO:0005515protein binding IPI19523114
         
    SRSF9 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SRSF9:
     Synthetic lethal with Ras 

    Animal Models:
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SRSF9 About   (see all 6)                                                                                              See pathways by source

    SuperPathContained pathways About
    1mRNA Splicing - Major Pathway
    Processing of Capped Intron-Containing Pre-mRNA0.85
    mRNA Splicing0.82
    mRNA Processing0.85
    mRNA processing0.46
    mRNA Splicing - Major Pathway0.82
    Spliceosome0.31
    2RNA Polymerase II Transcription Termination
    RNA Polymerase II Transcription Termination0.79
    Post-Elongation Processing of the Transcript0.79
    Post-Elongation Processing of Intron-Containing pre-mRNA0.79
    mRNA 3'-end processing0.79
    Cleavage of Growing Transcript in the Termination Region 0.79
    3Transport of Mature Transcript to Cytoplasm
    Transport of Mature Transcript to Cytoplasm0.85
    Transport of Mature mRNA derived from an Intron-Containing Transcript0.85
    4Transcription
    Transcription0.69
    RNA Polymerase II Transcription0.69
    5Generic Transcription Pathway
    Gene Expression0.47

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for SRSF9
        mRNA processing

    5/14        Reactome Pathways for SRSF9 (see all 14)
        Transport of Mature mRNA derived from an Intron-Containing Transcript
    mRNA Splicing - Major Pathway
    Transport of Mature Transcript to Cytoplasm
    mRNA Splicing
    RNA Polymerase II Transcription


    2         Kegg Pathways  (Kegg details for SRSF9):
        Spliceosome
    Herpes simplex infection


    SRSF9 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SRSF9

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/137 Interacting proteins for SRSF9 (Q132422, 3 ENSP000002293904) via UniProtKB, MINT, STRING, and/or I2D (see all 137)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HABP4Q5JVS02, 3, ENSP000003643984MINT-7041232 MINT-7041065 I2D: score=1 STRING: ENSP00000364398
    SF3A2Q154282, 3, ENSP000002214944MINT-5205728 I2D: score=1 STRING: ENSP00000221494
    C1QBPQ070213, ENSP000002256984I2D: score=3 STRING: ENSP00000225698
    TRA2BP629953, ENSP000004169594I2D: score=3 STRING: ENSP00000416959
    MAP1LC3AQ9H4923, ENSP000003639704I2D: score=2 STRING: ENSP00000363970
    About this table

    Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000398mRNA splicing, via spliceosome TAS--
    GO:0006366transcription from RNA polymerase II promoter TAS--
    GO:0006369termination of RNA polymerase II transcription TAS--
    GO:0006376mRNA splice site selection TAS7556075
    GO:0006397mRNA processing TAS7556075

    SRSF9 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SRSF9

    Search CenterWatch for drugs/clinical trials and news about SRSF9

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SRSF9 gene: 
    NM_003769.2  

    Unigene Cluster for SRSF9:

    Serine/arginine-rich splicing factor 9
    Hs.744094  [show with all ESTs]
    Unigene Representative Sequence: BG107695
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000229390(uc001tyi.3) ENST00000548326 ENST00000548792 ENST00000603963
    ENST00000550458 ENST00000546942(uc009zwy.2)

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    SwitchGear 3'UTR luciferase reporter plasmidSRSF9 3' UTR sequence
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    Additional mRNA sequence: 

    AK290644.1 AK294254.1 AK309778.1 BC093971.1 BC093973.1 U30825.1 

    11 DOTS entries:

    DT.99965724  DT.443296  DT.97855918  DT.419056  DT.121180209  DT.100645995  DT.100883530  DT.92448987 
    DT.95168853  DT.101954829  DT.102838255 

    24/413 AceView cDNA sequences (see all 413):

    BU173336 BM554930 CF127473 BQ957723 BQ774015 AW163065 CR617389 CK903352 
    AI990128 BQ955022 CR603096 BG741344 BF002679 AI685114 CR591670 W69647 
    AA010791 BE785705 BQ026457 CR598070 BF981478 BM987023 BQ227510 AI554406 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for SRSF9    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b · 4c
    SP1:                    -     -                           
    SP2:              -     -     -                           
    SP3:                                                      
    SP4:                                                      


    ECgene alternative splicing isoforms for SRSF9

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SRSF9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGGGTGAAAC
    SRSF9 Expression
    About this image


    See SRSF9 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SRSF9

    SOURCE GeneReport for Unigene cluster: Hs.744094

    UniProtKB/Swiss-Prot: SRSF9_HUMAN, Q13242
    Tissue specificity: Expressed at high levels in the heart, kidney, pancreas and placenta, and at lower levels in
    the brain, liver, lung and skeletal muscle

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SRSF9 gene from 7/18 species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Srsf91 , 5 serine/arginine-rich splicing factor 91, 5 93.48(n)1
    98.64(a)1
      5 (56.05 cM)5
    1080141  NM_025573.31  NP_079849.11 
     1153271775 
    lizard
    (Anolis carolinensis)
    Reptilia SRSF96
    Uncharacterized protein
    78(a)
    1 ↔ 1
    GL343338.1(73961-86753)
    African clawed frog
    (Xenopus laevis)
    Amphibia CA789729.12   -- 75.54(n)    CA789729.1 
    zebrafish
    (Danio rerio)
    Actinopterygii srsf91 serine/arginine-rich splicing factor 9 69.09(n)
    75.73(a)
      405835  NM_212899.1  NP_998064.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta SF26
    SF2
    45(a)
    1 → many
    3R(12164665-12167706)
    worm
    (Caenorhabditis elegans)
    Secernentea rsp-36
    Probable splicing factor, arginine/serine-rich 3
    46(a)
    1 → many
    III(12686461-12687922)
    rice
    (Oryza sativa)
    Liliopsida AK071503.12   -- 76.61(n)    AK071503.1 


    ENSEMBL Gene Tree for SRSF9 (if available)
    TreeFam Gene Tree for SRSF9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SRSF9 gene
    SRSF52  SRSF72  SRSF12  SRSF62  SRSF42  SRSF32  
    11 SIMAP similar genes for SRSF9 using alignment to 2 protein entries:     SRSF9_HUMAN (see all proteins):
    SRSF1    SFRS5    SRSF5    SFRS6    SRSF4    CIRBP
    RBMX    ELAVL1    SFRS3    SRSF7    SRSF6

    SRSF9 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for SRSF9
    PGOHUM00000246895 PGOHUM00000239077


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/95 SNPs in SRSF9 are shown (see all 95)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1881219361,2
    --117919397(+) TGCCTC/GCCACC 1 -- us2k10--------
    rs10501871,2
    C,F,A,H--120902111(-) CTCAAG/AGTGGT 1 -- int127Minor allele frequency- A:0.34EA MN NS NA CSA WA 4378
    rs1857393371,2
    --120902148(+) AGACCA/CGGCCT 1 -- int10--------
    rs5598381,2
    C,F--120902167(-) ACTTCT/CTGCTC 1 -- int12Minor allele frequency- C:0.06WA NA 238
    rs1900570661,2
    --120902210(+) TTCATA/GGCCTC 1 -- int10--------
    rs1460309811,2
    C--120902212(+) CATAG-/CCTCTT 1 -- int10--------
    rs5661241,2
    C,F,A,H--120902279(-) ATTTCA/GTAATG 1 -- int122Minor allele frequency- G:0.46NS EA NA WA CSA 2346
    rs1824682511,2
    C--120902317(+) ACAGGG/TTTTCA 1 -- int10--------
    rs791922631,2
    C,F--120902356(+) TGAAAT/AAACCA 1 -- int11Minor allele frequency- A:0.03WA 118
    rs110651311,2
    C--120902516(+) CTAGTC/TGGGAG 1 -- int10--------

    HapMap Linkage Disequilibrium report for SRSF9 (120899471 - 120907596 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for SRSF9:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2579823CNV Insertion19546169
    nsv509482CNV Insertion20534489

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 601943    OMIM disorders: --

    11 diseases for SRSF9:    About MalaCards
    distal hereditary motor neuropathy    primary open angle glaucoma    open-angle glaucoma    frontotemporal dementia
    glaucoma    dementia    bipolar disorder    neuropathy
    prostate cancer    prostatitis    neuronitis


    SRSF9 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Human Genome Epidemiology (HuGE) Navigator: SRSF9 (0 documents)

    Export disorders for SRSF9 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SRSF9 gene, integrated from 9 sources (see all 67):
    (articles sorted by number of sources associating them with SRSF9)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of three members of the human SR family of pre-mRNA splicing factors. (PubMed id 7556075)1, 2, 3, 9 Screaton G.R.... Krainer A.R. (1995)
    2. SRp30c is a repressor of 3' splice site utilization. (PubMed id 12024014)1, 2, 9 Simard M.J. and Chabot B. (2002)
    3. Splicing factor SRp30c interaction with Y-box protein-1 confers nuclear YB-1 shuttling and alternative splice site selection. (PubMed id 12604611)1, 2, 9 Raffetseder U.... Mertens P.R. (2003)
    4. Alternative splicing determines the intracellular localization of the novel nuclear protein Nop30 and its interaction with the splicing factor SRp30c. (PubMed id 10196175)1, 2, 9 Stoss O.... Stamm S. (1999)
    5. A rational nomenclature for serine/arginine-rich prot ein splicing factors (SR proteins). (PubMed id 20516191)1, 3 Manley J.L. and Krainer A.R. (2010)
    6. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
    7. The finished DNA sequence of human chromosome 12. (PubMed id 16541075)1, 2 Scherer S.E.... Gibbs R.A. (2006)
    8. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    9. Tau exons 2 and 10, which are misregulated in neurodegenerative diseases, are partly regulated by silencers which bind a SRp30c SRp55 complex that either recruits or antagonizes htra2beta1. (PubMed id 15695522)1, 2 Wang Y.... Andreadis A. (2005)
    10. Tra2 beta, SF2/ASF and SRp30c modulate the function of an exonic splicing enhancer in exon 10 of tau pre-mRNA. (PubMed id 15009090)1, 2 Kondo S....Imaizumi K. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8683 HGNC: 10791 AceView: SFRS9 Ensembl:ENSG00000111786 euGenes: HUgn8683
    ECgene: SRSF9 Kegg: 8683 H-InvDB: SRSF9

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SRSF9 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SRSF9 gene:
    Search GeneIP for patents involving SRSF9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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