SRSF7 Gene
protein-coding GIFtS: 52
GCID: GC02M038971
|
|
serine/arginine-rich splicing factor 7(Previous names: splicing factor, arginine/serine-rich 7 (35kD), splicing...)
(Previous symbol: SFRS7)
| |
Aliases
for SRSF7 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Serine/Arginine-Rich Splicing Factor 71 2 | | RBM371 | | SFRS71 2 3 5 | | ZCCHC201 | | 9G81 2 | | ZCRB21 | | AAG31 2 | | Splicing Factor, Arginine/Serine-Rich 7 (35kD)1 | | Splicing Factor, Arginine/Serine-Rich 7, 35kDa1 2 | | Aging-Associated Protein 32 | | Splicing Factor 9G82 3 | | SR Splicing Factor 72 | | HSSG11 | | Splicing Factor, Arginine/Serine-Rich 73 |
Export aliases for SRSF7 gene to outside databasesPrevious GC identifer: GC02M038709 |
Summaries
for SRSF7 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SRSF7:
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors,which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for bindingRNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitatesinteraction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteinshave also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variantsencoding different isoforms have been found for this gene. (provided by RefSeq, Sep 2010)
UniProtKB/Swiss-Prot: SRSF7_HUMAN, Q16629Function: Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing ofMAPT/Tau exon 10
Gene Wiki entry for SRSF7 (SFRS7)
|
Genomic Views
for SRSF7 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022184.15
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for SRSF7
Other transcription factors
Search SABiosciences Chromatin IP Primers for SRSF7
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SRSF7 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p22.1 Ensembl cytogenetic band: 2p22.1 HGNC cytogenetic band: 2p22.1SRSF7 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M038971: view genomic region
(about GC identifiers)
Start:
|
38,970,741 bp from pter |
End:
|
38,978,636 bp from pter |
Size:
|
7,896 bases |
Orientation:
|
minus strand |
|
Proteins
for SRSF7 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SRSF7_HUMAN, Q16629 (See
protein sequence)Recommended Name: Serine/arginine-rich splicing factor 7 Size: 238 amino acids; 27367 Da
Subunit: Found in large molecular weight complexes containing CCNL1 and the p110 isoforms of either CDC2L1 or CDC2L2.Interacts with CCNL2 and CPSF6
Subcellular location: Nucleus
1 PDB 3D structure from  and Proteopedia  for SRSF7:2HVZ (3D)
Secondary accessions: B4DLU6 G5E9M3 Q564D3Alternative splicing: 4 isoforms: Q16629-1 Q16629-2 Q16629-3 Q16629-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SRSF7: NX_Q16629
Post-translational modifications:
Extensively phosphorylated on serine residues in the RS domain1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q16629
SRSF7 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001026854.1 NP_001182375.1
ENSEMBL proteins: ENSP00000325905 ENSP00000400246 ENSP00000416516 ENSP00000392300 ENSP00000401202 ENSP00000386806 ENSP00000398159 ENSP00000402544 ENSP00000408868 ENSP00000402264 Reactome Protein details: Q16629
Human Recombinant Protein Products for SRSF7:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
SRSF7 for ontologies About GeneDecksing
SRSF7 Antibody Products:
Assay Products for SRSF7: |
Protein
Domains /
Families
for SRSF7 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SRSF7 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q16629ProtoNet protein and cluster: Q16629 2 Blocks protein families: IPB000504 RNA-binding region RNP-1 (RNA recognition motif) IPB001878 C2HC-type zinc-finger signature
UniProtKB/Swiss-Prot: SRSF7_HUMAN, Q16629Similarity: Belongs to the splicing factor SR familySimilarity: Contains 1 CCHC-type zinc fingerSimilarity: Contains 1 RRM (RNA recognition motif) domain |
Function
for SRSF7 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: SRSF7_HUMAN, Q16629Function: Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing ofMAPT/Tau exon 10 Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
SRSF7 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SRSF7 (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SRSF7
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): SRSF7 (NM_001031684) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SRSF7 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SRSF7 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SRSF7 |
|
Pathways & Interactions
for SRSF7 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | mRNA Splicing - Major Pathway | | | 2 | RNA Polymerase II Transcription Termination | | | 3 | Transcription | | | 4 | Transport of Mature Transcript to Cytoplasm | | | 5 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for SRSF7
5/15 
Reactome Pathways for SRSF7 (see all 15)
1 
Kegg Pathway (Kegg details for SRSF7):
SRSF7 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SRSF7
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/851 Interacting proteins for SRSF7 (Q166291, 2, 3 ENSP000003259054) via UniProtKB, MINT, STRING, and/or I2D (see all 851)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| NXF1 | Q9UBU92, 3, ENSP000002941724 | MINT-3380010 MINT-3380040 MINT-3380069 I2D:
score=4 STRING: ENSP00000294172 | | HNRNPK | P619782, 3, ENSP000003654394 | MINT-7945693 MINT-7947479 I2D:
score=1 STRING: ENSP00000365439 | | RBM39 | Q144982, 3, ENSP000002533634 | MINT-7945693 MINT-7947479 I2D:
score=1 STRING: ENSP00000253363 | | SF3A2 | Q154282, 3, ENSP000002214944 | MINT-5205710 MINT-7947479 I2D:
score=1 STRING: ENSP00000221494 | | SRRM1 | Q8IYB32, 3, ENSP000003262614 | MINT-7945693 MINT-7947479 I2D:
score=1 STRING: ENSP00000326261 |
About this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000398 | mRNA splicing, via spliceosome |
TAS | -- | | GO:0006366 | transcription from RNA polymerase II promoter |
TAS | -- | | GO:0006369 | termination of RNA polymerase II transcription |
TAS | -- | | GO:0006397 | mRNA processing |
TAS | 8013463 | | GO:0006406 | mRNA export from nucleus |
TAS | -- |
SRSF7 for ontologies About GeneDecksing
|
Drugs & Compounds
for SRSF7 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SRSF7 for compounds About GeneDecksing
 Browse Tocris compounds for SRSF7
3 Novoseek chemical compound relationships for SRSF7 gene About this table
Search CenterWatch for drugs/clinical trials and news about SRSF7
|
Transcripts
for SRSF7 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SRSF7 gene (3 alternative transcripts): NM_001031684.2 NM_001195446.1 NM_006276.36 Unigene Cluster for SRSF7: Serine/arginine-rich splicing factor 7 Hs.309090 [show with all ESTs]Unigene Representative Sequence: AK09142512 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000313117(uc002rqz.3 uc010ynp.2) ENST00000425778(uc002rra.3)
ENST00000425941 ENST00000452806 ENST00000432873 ENST00000409276 ENST00000477635
ENST00000431066 ENST00000443213 ENST00000487773 ENST00000415527 ENST00000446327
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SRSF7 (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SRSF7
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): SRSF7 (NM_001031684) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SRSF7 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SRSF7 |
Additional cDNA sequence: AB445102.1 AK091425.1 AK225141.1 AK293667.1 AK297161.1 AY166860.1 AY513287.1 BC000997.2 BC017369.2 BC017908.1 BC022328.1 BT006745.1 L22253.1 24/30 DOTS entries (see all 30): DT.100665423 DT.100665415 DT.100665412 DT.448709 DT.100665414 DT.92454680 DT.95372973 DT.100665422 DT.95372971 DT.95372974 DT.120947170 DT.92454691 DT.95372977 DT.95372978 DT.100038528 DT.100832829 DT.119441 DT.120947181 DT.95372983 DT.120947165 DT.100661989 DT.100665416 DT.100665418 DT.100665424 24/573 AceView cDNA sequences (see all 573): BP378046 AU137271 AA319848 AW195381 BM788206 BU166783 BU678024 CB529764 BM711343 AW338776 BM829487 CB529379 BQ673856 BU179158 AA430316 BM817651 BQ720304 AA649847 BU189028 AW513136 AW611553 AA425156 BM013604 BE908069
GeneLoc Exon Structure
5/15 Alternative Splicing Database (ASD) splice patterns (SP) for SRSF7 (see all 15) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | · | 7c | · | 7d | · | 7e | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | · |
|---|
|
| SP1: | | | | | | | | | - | | - | | | | | | | | | | - | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | - | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | - | | | | | | |
| SP4: | | | | | | | | | - | | - | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | - | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | - | | | | | | | | | |
| ExUns: | 11c |
|---|
|
| SP1: | | | |
| SP2: | | | |
| SP3: | | | |
| SP4: | | | |
| SP5: | | |
ECgene alternative splicing isoforms for SRSF7
|
Expression
for SRSF7 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SRSF7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCTCGGAGAT
About this image
See SRSF7 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SRSF7
SOURCE GeneReport for Unigene cluster: Hs.309090
UniProtKB/Swiss-Prot: SRSF7_HUMAN, Q16629Tissue specificity: Brain, liver, kidney and lung
SABiosciences Expression via Pathway-Focused PCR Array including SRSF7:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SRSF7
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SRSF7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SRSF7 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SRSF7 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SRSF7 |
Orthologs
for SRSF7 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SRSF7 gene from 8/28 species (see all 28) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
LOC1008596091 |
uncharacterized LOC100859609 |
75.32(n)
93.62(a) |
|
100859609 XM_003640934.1 XP_003640982.1 |
lizard
(Anolis carolinensis) |
Reptilia |
SRSF76 |
-- |
94(a) |
1 ↔ 1 |
1(254028910-254037996) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.248062 |
Xenopus laevis transcribed sequence with moderate similarity more |
83.27(n) |
|
CA987868.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufb39b022 |
Transcribed sequence with weak similarity to protein more |
74.39(n) |
|
CD759186.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
x161 |
CG10203-PA |
44.8(n)
50.23(a) |
|
33967 NM_164718.1 NP_723226.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
rsp-61 |
Protein RSP-6 |
48.08(n)
57.47(a) |
|
177566 NM_171383.2 NP_741446.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT2G245901 |
RNA recognition motif and CCHC-type zinc finger domain-containing more |
50.69(n)
49.11(a) |
|
816995 NM_128020.4 NP_180035.1 |
rice
(Oryza sativa) |
Liliopsida |
Os02g06106001 |
hypothetical protein |
47.24(n)
53.48(a) |
|
4329951 NM_001053935.1 NP_001047400.1 |
ENSEMBL Gene Tree for SRSF7 (if available)
TreeFam Gene Tree for SRSF7 (if available) |
Paralogs
for SRSF7 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SRSF7 gene
- LOC1009966572 SRSF42 SRSF122 SRSF102 SRSF92 SRSF52 SRSF22 SRSF12
- SRSF62 SRSF32
11 SIMAP similar genes for SRSF7 using alignment to 5 protein entries: SRSF7_HUMAN (see all proteins):SFRS3 SRSF3 SFRS6 RALY SFRS5 SRSF9
SRSF12 SRSF5 SFRS2 ZCRB1 SRSF10
SRSF7 for paralogs About GeneDecksing
|
Genomic Variants
for SRSF7 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SRSF7 (38970741 - 38978636 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SRSF7: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SRSF7 |
|
Disorders
/ Diseases
for SRSF7 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SRSF7 for disorders About GeneDecksing
OMIM gene information: 600572
OMIM disorders: --
13  diseases for SRSF7: About MalaCardsallergic bronchopulmonary aspergillosis frontotemporal dementia aspergillosis hypobetalipoproteinemia
herpes simplex bipolar disorder dementia parkinson's disease
hepatocellular carcinoma schizophrenia carcinoma malaria
hiv type 1
1 Novoseek disease relationship for SRSF7 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| shock |
15 |
5 |
15458974 (1), 9523846 (1), 17623484 (1) |
Export disorders for SRSF7 gene to outside databases
|
Publications
for SRSF7 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SRSF7 gene, integrated from 9 sources (see all 77):
(articles sorted by number of sources associating them with SRSF7) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization and cloning of the human splicing factor 9G8: a novel 35 kDa factor of the serine/arginine protein family. (PubMed id 8013463)1, 2, 3, 9 Cavaloc Y.... Stevenin J. (1994)
- The gene encoding human splicing factor 9G8. Structure, chromosomal localization, and expression of alternatively processed transcripts. (PubMed id 7629084)1, 2, 9 Popielarz M.... Stevenin J. (1995)
- Cyclin L2, a novel RNA polymerase II-associated cyclin, is involved in pre-mRNA splicing and induces apoptosis of human hepatocellular carcinoma cells. (PubMed id 14684736)1, 2, 9 Yang L.... Cao X. (2004)
- Novel cis-active structures in the coding region medi ate CRM1-dependent nuclear export of IFN-I+ 1 mRNA. (PubMed id 20857263)1, 2 Kimura T....Yamada H. (2010)
- A rational nomenclature for serine/arginine-rich prot ein splicing factors (SR proteins). (PubMed id 20516191)1, 3 Manley J.L. and Krainer A.R. (2010)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Distinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localization. (PubMed id 15169763)1, 2 Dettwiler S.... Barabino S.M. (2004)
- Tau exon 10, whose missplicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors. (PubMed id 15009664)1, 2 Wang J....Andreadis A. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
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External Searches for SRSF7 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing SRSF7 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing SRSF7 gene
(According to HUGE)
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Specialized Databases showing SRSF7 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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|
| Name | Description |
| PharmGKB entry for SRSF7 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for SRSF7 gene:
Search GeneIP for patents involving SRSF7
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for SRSF7 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SRSF7 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SRSF7 | | | OriGene Protein Over-expression Lysate for SRSF7 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SRSF7 | | OriGene 3'-UTR Clone for SRSF7 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SRSF7 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SRSF7 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SRSF7 | | OriGene Custom Protein Services for SRSF7 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SRSF7 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SRSF7 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SRSF7 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SRSF7 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SRSF7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SRSF7 |
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| | | | Search Tocris compounds for SRSF7 |
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 | | | SRSF7 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SRSF7 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for SRSF7 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SRSF7 |
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